An S-selective and meta-regioselective arylation of sulfenamides with cyclic diaryl λ3-bromanes and λ3-chloranes under mild conditions has been exploited. It delivers S-aryl sulfilimines in good to excellent yields with high regioselectivity.
In this article, recent advances in catalytic asymmetric synthesis of chiral sulfilimines from sulfenamides via S–C bond formation are highlighted.
An efficient Cu-catalyzed sulfilimine synthesis via aryl-, alkyl- and alkenylation of sulfenamides using readily accessible TT salts was developed. Mechanistic studies demonstrate the importance of EDA intermediates and bifunctional Cu catalyst.
The collagen IV network plays a crucial role in providing structural support and mechanical integrity to the basement membrane and surrounding tissues.
Sulfilimines were exploited as valuable moieties in organic synthesis and medicinal chemistry, however, efficient methods for constructing such scaffolds remain limited. Herein, we disclosed a convenient method for modular synthesis...