Tungsten-catalyzed continuous-flow oxidation of sulfides to sulfones with hydrogen peroxide

Yasushi Okamoto, Kazuhiro Matsumoto, Jun-Chul Choi, Yoshihiro Kon and Ken-ichi Fujita

Org. Biomol. Chem., 2026, 24, 2439
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A miniaturized ozonolysis flow platform for expeditious sulfur mustard warfare simulant neutralization

Maxime Boddaert, Pauline Bianchi, Diana V. Silva-Brenes, Ancuta Musina, Marc Winter, Philippe M. C. Roth, Pierre-Yves Renard, Julien Legros and Jean-Christophe M. Monbaliu

Green Chem., 2024, 26, 1281
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An integrated five-step continuous flow synthesis of 2-(1-cyclohexenyl)ethylamine: a key intermediate for morphinans

Zhining Li, Shiqi Huang, Yuan Tao, Meifen Jiang, Dang Cheng, Li Wan and Fener Chen

React. Chem. Eng., 2023, 8, 1882
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Telescoped continuous flow synthesis of benzimidazoles from o-phenylenediamines and carboxylic acids

Qilin Xu, Zhihao Ma, Fucheng Zhu, Guosi Li, Yidong Zhong, Dong Liu and Yongjun Zang

Org. Chem. Front., 2026, 13, 917
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Rapid preparation of waterborne polyurethane dispersions using continuous-flow microreaction technology

Wenjun Huang, Xuanyu Chen, Qianjiang Lv, Xiaolan Cai, Wei Tan and Yanxiong Fang

React. Chem. Eng., 2025, 10, 1326
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Enzyme immobilization on a 3D-printed reactor for aldehyde oxidation to carboxylic acid under mild conditions

Kou Nakahara, Kotchakorn T.sriwong, Muhammad Arisyi Hawari, Akira Tanaka and Tomoko Matsuda

React. Chem. Eng., 2023, 8, 543
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Continuous flow oxidation of HMF using a supported AuPd-alloy

Dominik Neukum, Ajai R. Lakshmi Nilayam, Maya E. Ludwig, Athanasios A. Vadarlis, Jan-Dierk Grunwaldt and Erisa Saraçi

Catal. Sci. Technol., 2024, 14, 2130
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Wood-inspired dual-scale directional channel cellulose bioreactors with high mass transfer efficiency for continuous flow catalytic green conversion

En-Jiang Liu, Yu-Shi Shen, Mei-Yan Ling, Chen-Xi He, Xing Zhou, Jun Wang, Shuai You, Wei-Guo Zhao, Xiao-Hui Yao and Dong-Yang Zhang

Green Chem., 2024, 26, 8256
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Will the next generation of chemical plants be in miniaturized flow reactors?

Jean-Christophe M. Monbaliu and Julien Legros

Lab Chip, 2023, 23, 1349
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Systematic study of FFF materials for digitalizing chemical reactors with 3D printing: superior performance of carbon-filled polyamide

Victoria A. Korabelnikova, Evgeniy G. Gordeev and Valentine P. Ananikov

React. Chem. Eng., 2023, 8, 1613
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A green and efficient monoacylation strategy for symmetrical diamines in microreactors

Qilin Xu, Hui Liu, Zhenxin Li, Yongjun Zang, Guosi Li, Fucheng Zhu, Shitang Ma, Yunfeng Ma and Maoliang Liao

React. Chem. Eng., 2024, 9, 2411
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Diverse continuous photooxygenation reactions of (+) and (−)-α-pinenes to the corresponding pinocarvones or trans-pinocarveols

Gabriel H. S. Rosa, Thiago I. S. Santos, Timothy J. Brocksom and Kleber T. de Oliveira

React. Chem. Eng., 2023, 8, 790
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Selective aerobic oxidation of aliphatic aldehydes: the critical role of percarboxylate anion on the selectivity

Laurent Vanoye and Alain Favre-Réguillon

React. Chem. Eng., 2023, 8, 1043
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Controlling explosive and highly energetic reactions: scaling up the liquid-phase aerobic oxidation of alcohols and aldehydes in flow

Boris Guicheret, Marco Antonio Dos-Santos, Claude de Bellefon, Laurent Vanoye, Régis Philippe and Alain Favre-Réguillon

React. Chem. Eng., 2026
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Continuous-flow synthesis of N,N′-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexanediamine (DTMPA) in a Micro fixed-bed reactor

Liang Gao, Liangchuan Lai, Baijun Ye, Minjie Liu, Dang Cheng, Meifen Jiang and Fener Chen

J Flow Chem, 2022, 12, 419
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Flow chemistry based catalytic hydrogenation for improving the synthesis of 1-deoxynojirimycin (DNJ) from an l-sorbose derived precursor

Jack J. Bennett and Paul V. Murphy

Carbohydrate Research, 2023, 529, 108845
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Efficient “One-Column” grignard generation and reaction in continuous flow

Maolin Sun, Hong Li, Hualiang Chen, Rixin Shao, Fanghua Chen, Xiangmin Sang, Weixia Lin, Yueyue Ma, Ruihua Cheng and Jinxing Ye

J Flow Chem, 2024, 14, 623
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Boron in My Mind: A Comprehensive Review of the Evolution of the Diverse Syntheses of 4‐Borono‐l‐Phenylalanine, the Leading Agent for Boron Neutron Capture Therapy

Sarfraz Ahmad, Ming Pan, John J. Hayward, Massimo Sementilli, Lisa A. Porter and John F. Trant

ChemMedChem, 2025, 20
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Bimetallic TiO2 Nanoparticles for Lignin-Based Model Compounds Valorization by Integrating an Optocatalytic Flow-Microreactor

Swaraj Rashmi Pradhan, Marta Paszkiewicz-Gawron, Dariusz Łomot, Dmytro Lisovytskiy and Juan Carlos Colmenares

Molecules, 2022, 27, 8731
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Efficient synthesis and reaction kinetic study of gem-Dibromoenones in continuous-flow microreactor

Hui Yang, Daofan Ma, Chunying Zhu, Taotao Fu, Guangwei Wang and Youguang Ma

Chemical Engineering Journal, 2025, 524, 168957
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Oxidative Neutralisation of Sulfur‐Based Chemical Warfare Agents Mediated by a Lipase: From Batch to Flow Reactor

Maxime Boddaert, Valmir Baptista da Silva, Sergui Mansour, Daniela Vuluga, Pierre‐Yves Renard, Jean‐Christophe M. Monbaliu and Julien Legros

Chemistry A European J, 2025, 31
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Continuous Flow Epoxidation of Alkenes Using a Homogeneous Manganese Catalyst with Peracetic Acid

Ailbhe A. Ryan, Seán D. Dempsey, Megan Smyth, Karen Fahey, Thomas S. Moody, Scott Wharry, Paul Dingwall, David W. Rooney, Jillian M. Thompson, Peter C. Knipe and Mark J. Muldoon

Org. Process Res. Dev., 2023, 27, 262
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Characterization of liquid-liquid two-phase flow patterns and mass transfer coefficients in Human-shaped microchannels

Haibo Zhu, Zhaoyang Shen, Lei Ni, Zhiquan Chen, Feng Xu and Juncheng Jiang

Chemical Engineering and Processing - Process Intensification, 2024, 201, 109820
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Ultrasound‐Assisted Microcontinuous Process Facilitates the Selective Deuteration of Steroid Hormones

Dan Wang, Xin Lv and Fang Wei

Labelled Comp Radiopharmac, 2025, 68
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Continuous-Flow Electrochemical Oxidation of Alkylarenes and Diarylmethanes to Aromatic Ketones Using Water under Catalyst-, Mediator-, and Additive-Free Conditions

Liu Yang, Lu-Yu Zou, Jing-Heng Zhu, Ai-Hua Yin, Sheng-Geng Fu, Chun-Ling Zheng, Guowei Wang, Zheng Fang, Chang-Sheng Wang and Qiao Sun

J. Org. Chem., 2025, 90, 17433
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Modelling approaches to predict light absorption in gas-liquid flow photosensitized oxidations

Anca Roibu, Keiran Mc Carogher, Rishi Bharadwaj Morthala, Roy Eyckens and Simon Kuhn

Chemical Engineering Journal, 2023, 452, 139272
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Scalable and sustainable synthesis of functionalized terpene acrylates in continuous flow: application of a multiphase, ultrasound-assisted mini-flow reactor

Franziska Obermeier, Martin Gostner and Oliver I. Strube

J Coat Technol Res, 2025, 22, 1251
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An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia and Fen-Er Chen

Engineering, 2024, 32, 226
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Flow photochemistry — from microreactors to large-scale processing

Mengxue Zhang and Philippe Roth

Current Opinion in Chemical Engineering, 2023, 39, 100897
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Continuous Flow Oxidation of Alcohols Using TEMPO/NaOCl for the Selective and Scalable Synthesis of Aldehydes

Parth Naik, Jorge García-Lacuna, Patrick O’Neill and Marcus Baumann

Org. Process Res. Dev., 2024, 28, 1587
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On-Demand Production of Two Commercial Plant Activators, Tiadinil and Methiadinil, under an Integrated Continuous Flow System

Zhengqi Fang, Jian Zhou, Dong Xing, Haibing He and Shuanhu Gao

Org. Process Res. Dev., 2024, 28, 3143
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Macro-Microdevice-Based Process Intensification of Gas–Liquid Chemical Processes

Hongyu Huang, Chao Li, Hanyu Jiang, Xin Hu, Shuangfei Zhao, Wei He, Kai Guo and Ning Zhu

Ind. Eng. Chem. Res., 2025, 64, 21933
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High-temperature S–S, S–O, and S–C bond transfer hydrogenolysis by lower alcohols in continuous flow mode

Andrey M. Chibiryaev, Ivan V. Kozhevnikov and Oleg N. Martyanov

J Flow Chem, 2025, 15, 131
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Continuous Processing for Manufacturing of Antibody–Drug Conjugates (ADCs)

Subhankar Metya, Pragya Prakash and Anurag S. Rathore

Bioconjugate Chem., 2026, 37, 395
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Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes

Annechien A. H. Laporte, Tom M. Masson, Stefan D. A. Zondag and Timothy Noël

Angewandte Chemie, 2024, 136
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Oxidative Cleavage of β-Substituted Primary Alcohols in Flow

Michael Tapera, Athanasios Savvidis, Cedric Meysing, Adrián Gómez-Suárez and Stefan F. Kirsch

Org. Lett., 2026, 28, 681
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Hydrodynamics and mass transfer of liquid-liquid two-phase flow in circular milli-channels: Sizing-up effect

Gang Fu, Feifei Chen, Dan Wei, Lei Ni, Juncheng Jiang and Yong Pan

Journal of the Taiwan Institute of Chemical Engineers, 2022, 141, 104602
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Electrophilic cyclization of reticuline-type alkaloids in flow via o-quinol intermediates

Bi Bali Judicaël Tra, Abollé Abollé, Killian Lucas and François-Xavier Felpin

J Flow Chem, 2023, 13, 257
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Elucidating molecular characteristics of organic compounds during ozone micro-bubbles treatment based on GC × GC-QTOF-MS and non-targeted analysis

Hang Xu, Weihang Chen, Qian Zhang, Ninghui Song and Mingmei Ding

Journal of Environmental Management, 2025, 375, 124196
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Continuous Stripping with Dense Carbon Dioxide

Márton Kőrösi, Petra Kántor, Péter Bana and Edit Székely

ACS Omega, 2023, 8, 46757
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Toward sustainable and scalable synthesis of ibuprofen: Integrative insights into batch and continuous flow strategies

Weichen Yang, Yuxin Liu, Runzi Li, Jie Lv, Youli Zhang, Yanrong Ren, Ziliang Yuan and Zehui Zhang

AIChE Journal, 2026, 72
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Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes

Annechien A. H. Laporte, Tom M. Masson, Stefan D. A. Zondag and Timothy Noël

Angew Chem Int Ed, 2024, 63
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Light-Driven Photobiocatalytic Oxyfunctionalization in a Continuous Reactor System without External Oxygen Supply

Lenny Malihan-Yap, Qian Liang, Alessia Valotta, Véronique Alphand, Heidrun Gruber-Woelfler and Robert Kourist

ACS Sustainable Chem. Eng., 2025, 13, 3939
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Two-Step Continuous Synthesis of Cabozantinib in a Microreactor: Mechanism and Kinetics Research of EDCI/HOBt-Mediated Amidation

Qilin Xu, Jingli Dai, Fucheng Zhu, Yongjun Zang, Guosi Li, Chaoyue Sun, Fengxia An, Dong Liu, Yidong Zhong and Maoliang Liao

Ind. Eng. Chem. Res., 2025, 64, 322
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Oxidation of Alcohols and Aldehydes with Peracetic Acid and a Mn(II)/Pyridin‐2‐Carboxylato Catalyst: Substrate and Continuous Flow Studies

Ailbhe A. Ryan, Seán D. Dempsey, Megan Smyth, Karen Fahey, Thomas S. Moody, Scott Wharry, Paul Dingwall, David W. Rooney, Jillian M. Thompson, Peter C. Knipe and Mark J. Muldoon

ChemCatChem, 2024, 16
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Selective and scalable oxygenation of heteroatoms using the elements of nature: air, water, and light

Damiano Diprima, Hannes Gemoets, Stefano Bonciolini and Koen Van Aken

Beilstein J. Org. Chem., 2023, 19, 1146
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Molecular Engineering and Utilization of Cyclohexanone Monooxygenase in the Cascade Biocatalytic Synthesis of ε-Caprolactone

Yingjiao Zhang, Jialong Zhang, Shengliang Cai, Tao Wu, Dongying Chen, Hao Yu and Shuang Li

ACS Sustainable Chem. Eng., 2025, 13, 6090
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Visible-Light-Driven α-Hydroxymethylation of Ketones in a Continuous-Flow Microreactor

Huinan Sun, Jianing Li, Lei Yun, Cunfei Ma, Zongyi Yu, Hongfei Zhu, Qingwei Meng and Jingnan Zhao

Synlett, 2023, 34, 86
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Novel one-step flow chemistry procedure for synthesizing isochromane derivatives

Anders E. Tønder, Jonas N.N. Eildal, Anders Bach and Johan E. Bajtner

Tetrahedron Letters, 2026, 179, 156030
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