Bifidobacterium longum-Derived Extracellular Vesicles Prevent Hepatocellular Carcinoma by Modulating the TGF-β1/Smad Signaling in Mice

Bin Li, Xiaochen Chi, Ying Huang, Weitong Wang and Zhuo Liu

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Pharmacological actions and applications of safflower flavonoids

Fajian Ren, Zhen Tan, Sheng Hu, Chaolong Rao, Qiwen Xiang, Jiayu Wen, Yan Chen and Cheng Peng

Front. Nutr., 2025, 12
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Advances in the role of gut microbiota in the regulation of the tumor microenvironment (Review)

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The effects of traditional Chinese medicine and dietary compounds on digestive cancer immunotherapy and gut microbiota modulation: A review

Xiaoli Feng, Zhenhao Li, Weihong Guo and Yanfeng Hu

Front. Immunol., 2023, 14
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Natural flavonoids from herbs and nutraceuticals as ferroptosis inhibitors in central nervous system diseases: current preclinical evidence and future perspectives

Qiuhe Li, Xiaohang Yang and Tiegang Li

Front. Pharmacol., 2025, 16
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The role of Traditional Chinese Medicine in the management of liver disease: targeting gut microbiome

Yifan Zhang, Hongkun Li, Fei Yu, Mengmeng Gao, Yang Wang, Siyu Xin, Jiating Yang, Zhiwei Wang, Lujie Xiang, Qingjing Ru and Na Jiang

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Targeted modulation of gut microbiota by traditional Chinese medicine and natural products for liver disease therapy

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Inhibitory Effects of Mongolian Medicine Yihe-Tang on Continuous Darkness Induced Liver Steatosis in Zebrafish

Rigaiqiqige Sa, Chi Feng, Hongxia Bai, Xiaoyu Yin, Lei Song, Xiaodong Hu, Rui Xu, Xinshan Li, Wu Dong, Jingfeng Yang and Jelena Zivkovic

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Mitigation strategies for gastrointestinal (GI) immune-related adverse events for patients with solid tumors receiving immunotherapy

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Total glucosides of paeony inhibit breast cancer growth by inhibiting TAMs infiltration through NF-κB/CCL2 signaling

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Luteolin Alleviates Liver Fibrosis in Rat Hepatic Stellate Cell HSC-T6: A Proteomic Analysis

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Gut microbiota-metabolism-immunity axis: a novel perspective of traditional Chinese medicine in hepatocellular carcinoma treatment

Xuemei Zhang, Liming Zheng, Jia Shi, Shihan Yu, Wenlan Zheng, Hao Liu, Zhengzheng Wu, Hai Feng, Yueqiu Gao and Zhuo Yu

Chin Med, 2026, 21
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Pro-Health Potential of Selected Uncommon Oilseed Plants

Karolina Dereń, Joanna Kapusta-Duch, Teresa Leszczyńska, Barbara Borczak and Marta Kotuła

Applied Sciences, 2024, 14, 8843
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Saprophytic fungus (Ganoderma sessile) restrained Treg recruitment in the tumor microenvironment by down-regulating CCL28/CCR10 pathway

Lu Jin, Jianhui Fu, Xiaochen Lin, Lushuai Jin, Yingxue Guo, Xia Liu, Shaden A.M. Khalifa, Hesham R. El-Seedi, Huiying Fu and Qiyang Shou

Journal of Functional Foods, 2024, 123, 106573
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The landscape of gut microbiota in hepatocarcinogenesis: a comprehensive review of pathogenesis and therapeutic interventions

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Quantitative comparison on the similarities and differences of Mongolian medicines in the treatment of liver diseases between China and Mongolia based on data mining

Congying Huang, Baochang Zhou, Aruhan Chen, Budanbaila La, Yu Ye, Yibo Liu, Xinyu Zhang, Yanhong Sun, Agula Bo and Minhui Li

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Exploring the anti-fibrotic effects of safflower in systemic sclerosis based on metabolomics and gut microbiota analyses

Yu Zhang, Xingfeng Ping, Chao Wang, Xueyan Zhou, Yi Huang, Kai Li and Junying Lv

Front. Pharmacol., 2026, 17
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Safflower yellow alleviates cognitive impairment in mice by modulating cholinergic system function, oxidative stress, and CREB/BDNF/TrkB signaling pathway

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Potential of Compounds Originating from the Nature to Act in Hepatocellular Carcinoma Therapy by Targeting the Tumor Immunosuppressive Microenvironment: A Review

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Gut Microbiota and Hepatocellular Carcinoma: Metabolic Products and Immunotherapy Modulation

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Cancer Medicine, 2025, 14
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Safflower Yellow Pigment Alleviates Cerebral Ischemia‐Reperfusion Injury via Protein Nitration and Oxidative Modulation

Kun Wang, Xi Zhang, Yang Zhao, Lifeng Li and Ruijie Zhao

Brain and Behavior, 2025, 15
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Uncovering the pharmacological foundation of NLXT through an ischemic stroke rat model combined with UHPLC-QTOF/MS techniques

Xiao Shi, Xuefeng Jia, Yu Bi, Jiaqi Wang, Zhongwen Xie, Jianpeng Hu and Lina Wang

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Efficacy and safety of safflower yellow combined with low molecular weight heparin in preventing deep vein thrombosis after orthopedic surgery: a systematic review and meta-analysis

Qiuyu Li

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Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine

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Acta Pharmaceutica Sinica B, 2023, 13, 3598
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Applications of traditional Chinese medicine in cancer immunotherapy via gut microbiota modulation: Current status, mechanisms, challenges and perspectives

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Pharmacological Research, 2025, 222, 108020
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Effects of Saffron Yellow A as an Extract of Saffron on the Recovery Treatment and Organ Function of Patients with Sepsis

Ziwei Wang, Liqin Yao, Xiaoyu Cheng, Lei Xu and Yao Song

sci adv mater, 2023, 15, 1629
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A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways

Md. Rezaul Islam, Abdur Rauf, Shopnil Alash, Md Naeem Hossain Fakir, Gazi Kaifeara Thufa, Mahbuba Sharmin Sowa, Dattatreya Mukherjee, Harendra Kumar, Md Sadique Hussain, Abdullah S. M. Aljohani, Muhammad Imran, Waleed Al Abdulmonem, Rekha Thiruvengadam and Muthu Thiruvengadam

Med Oncol, 2024, 41
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Therapeutic Effects of Natural Products on Liver Cancer and Their Potential Mechanisms

Jinhong Guo, Wenjie Yan, Hao Duan, Diandian Wang, Yaxi Zhou, Duo Feng, Yue Zheng, Shiqi Zhou, Gaigai Liu and Xia Qin

Nutrients, 2024, 16, 1642
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Comprehensive review of two groups of flavonoids in Carthamus tinctorius L.

Bin Xian, Rui Wang, Huajuan Jiang, Yongfeng Zhou, Jie Yan, Xulong Huang, Jiang Chen, Qinghua Wu, Chao Chen, Ziqing Xi, Chaoxiang Ren and Jin Pei

Biomedicine & Pharmacotherapy, 2022, 153, 113462
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Safflower Yellow Inhibits Progression of Hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway

Hua-feng Ji, Zi-qiang Yang, Jun-jun Han, He-fang Li, Zhao-qing Jin, Wei-qing Chen, Fei-hua Chen and Mou-chun Gong

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Potential of natural products and gut microbiome in tumor immunotherapy

Luchang Cao, Xinmiao Wang, Xinyi Ma, Manman Xu and Jie Li

Chin Med, 2024, 19
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