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Smart polymers represent a class of advanced materials that undergo reversible changes in their physical or chemical form and are known as responsive polymers. These polymers show transitions when external stimuli, such as temperature and pH, come into play. Smart polymers are being increasingly applied in various fields, such as drug delivery to a targeted site and gene therapy. They also play a pivotal role in tissue engineering, environmental sensors, and the development of shape memory polymers. Despite their major challenges, they remain effective in overcoming significant barriers. It can be said that these polymers have the potential to revolutionize various fields. This review highlights the underlying types and applications of smart polymers, emphasizing their roles in the future.

Graphical abstract: Smart polymers: key to targeted therapeutic interventions

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