Issue 63, 2018

Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagents

Abstract

A copper-mediated intramolecular aminofluorination of 1,3-dienes is disclosed, in which both AgF and Et3N·3HF can be used as the fluorine source. This protocol provides a variety of pyrrolidines bearing allylic fluorides with excellent regioselectivities and good diastereoselectivities.

Graphical abstract: Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagents

Supplementary files

Article information

Article type
Communication
Submitted
20 جوٗن 2018
Accepted
11 جوٗلایی 2018
First published
11 جوٗلایی 2018

Chem. Commun., 2018,54, 8709-8712

Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagents

Z. Zhang, P. Chen and G. Liu, Chem. Commun., 2018, 54, 8709 DOI: 10.1039/C8CC04909B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements