Issue 30, 2023

Supramolecular recognition enhanced electrochemical sensing: β-cyclodextrin and Pd nanoparticle co-decorated 3D reduced graphene oxide nanocomposite-modified glassy carbon electrode for the quantification of ractopamine

Abstract

Ractopamine (RAC) is universally known for improving lean meat percentage in livestock and thus is widely introduced as a feed additive. However, it is difficult to eliminate the RAC residue in animal tissues from the biological system and will inevitably harm human health. Hence, detecting RAC molecules in biological samples is extremely significant. Herein, a novel strategy of supramolecular recognition-enhanced electrochemical sensing is presented. This platform was constructed by coupling β-cyclodextrin (β-CD) with palladium nanoparticles (Pd NPs)-functionalized three-dimensional reduced graphene oxide (3D-rGO) to form a nanocomposite (3D-rGO/Pd/β-CD), which was further used to modify a glassy carbon electrode (GCE) for RAC detection. Benefiting from the attractive electrical conductivity and catalytic activity of 3D-rGO/Pd, as well as the unique small-molecule-recognition ability of β-CD demonstrated by 1H NMR spectrum, which revealed the 1 : 2 binding mode of RAC with β-CD, increased peak current signals of RAC were observed in the cyclic voltammetry (CV) test. Under optimized conditions, the wide linear concentration range spanned 1–95 μM, along with a relatively low detection limit of 0.12 μM (S/N = 3), as evidenced by the differential pulse voltammetry (DPV) approach. The platform also exhibited satisfactory stability and fine reproducibility, as well as high selectivity and good anti-interference capability. Moreover, this as-obtained sensor was efficiently applied in pork samples with a high recovery rate (96.44–103.99%), which provides a promising view of its electrochemical biosensing ability in practical applications.

Graphical abstract: Supramolecular recognition enhanced electrochemical sensing: β-cyclodextrin and Pd nanoparticle co-decorated 3D reduced graphene oxide nanocomposite-modified glassy carbon electrode for the quantification of ractopamine

Supplementary files

Article information

Article type
Paper
Submitted
29 میٔ 2023
Accepted
07 جوٗلایی 2023
First published
07 جوٗلایی 2023

Anal. Methods, 2023,15, 3642-3649

Supramolecular recognition enhanced electrochemical sensing: β-cyclodextrin and Pd nanoparticle co-decorated 3D reduced graphene oxide nanocomposite-modified glassy carbon electrode for the quantification of ractopamine

K. Zhang, X. Zhang, Y. Rong, Q. Niu, P. Jin, X. Ma, C. Yang and W. Liang, Anal. Methods, 2023, 15, 3642 DOI: 10.1039/D3AY00872J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements