Background free in vivo29Si MR imaging with hyperpolarized PEGylated silicon nanoparticles

Abstract

This study demonstrated the potential of 50 nm PEGylated Si NPs for high-resolution in vivo²⁹Si MR imaging, emphasizing their biocompatibility and water dispersibility. The acquisition of in vivo Si MR images using the lowest reported dose after subcutaneous and intraperitoneal administration opens new avenues for future ²⁹Si MR studies.