Issue 4, 2015

CO-enabled rhenium hydride catalyst for directed C(sp2)–H bond alkylation with olefins

Abstract

We report the first example of CO-enabled rhenium hydride complex-catalyzed inter- and intra-molecular hydroarylation of activated alkenes, with a broad reaction scope. α,β-Unsaturated ketones, esters and amides are all suitable for this transformation. It affords a novel and convenient protocol to construct 3-methylindolones. In addition, mechanistic investigations suggest that a rhenium carbonyl hydride species may act as a key intermediate.

Graphical abstract: CO-enabled rhenium hydride catalyst for directed C(sp2)–H bond alkylation with olefins

Supplementary files

Article information

Article type
Research Article
Submitted
15 دسمبر 2014
Accepted
31 جنؤری 2015
First published
03 فرؤری 2015

Org. Chem. Front., 2015,2, 378-382

Author version available

CO-enabled rhenium hydride catalyst for directed C(sp2)–H bond alkylation with olefins

H. Jin, Z. Zhu, N. Jin, J. Xie, Y. Cheng and C. Zhu, Org. Chem. Front., 2015, 2, 378 DOI: 10.1039/C4QO00329B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements