Construction of thiazines and oxathianes via [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: application towards the synthesis of bioactive molecules

Rohit Kumar Varshnaya; Prabal Banerjee

doi:10.1039/C7OB00941K

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Construction of thiazines and oxathianes via [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: application towards the synthesis of bioactive molecules†

Rohit Kumar Varshnaya^a and Prabal Banerjee

*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, Indian Institute of Technology Ropar, Nangal Road, Rupnagar, Punjab-140001, India
E-mail: prabal@iitrpr.ac.in
Web: http://www.iitrpr.ac.in/chemistry/prabal
Fax: +911881223395

Abstract

Lewis acid catalyzed [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with in situ generated mercaptoaldehyde for the synthesis of functionalized thiazine and oxathiane derivatives has been developed. Additionally, this method facilitates the derivatization of thiazines by detosylation and Krapcho monodecarboxylation.

This article is part of the themed collection: Celebrating the RAOBC symposium

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/C7OB00941K
Article type: Paper
Submitted: 17 اپریل 2017
Accepted: 30 میٔ 2017
First published: 31 میٔ 2017

Download Citation

Org. Biomol. Chem., 2017,15, 5182-5190

Permissions

Request permissions

Construction of thiazines and oxathianes via [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: application towards the synthesis of bioactive molecules

R. K. Varshnaya and P. Banerjee, Org. Biomol. Chem., 2017, 15, 5182 DOI: 10.1039/C7OB00941K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Organic & Biomolecular Chemistry

Construction of thiazines and oxathianes via [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: application towards the synthesis of bioactive molecules†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Construction of thiazines and oxathianes via [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: application towards the synthesis of bioactive molecules

Social activity

Search articles by author

Spotlight

Advertisements