The recent advances of the visible-light-mediated photocatalytic cleavage of C–C and C–N bonds associated with amines and their derivatives, which featuring mild conditions, unique selectivity, broad substrate scope and green manner, are reviewed.
Photocatalytic ring opening of aminocyclopropanes enables the selective installation of N-acyl-N,O-acetal linkers on pyridines, thereby facilitating diverse downstream functionalizations and efficient late-stage molecular editing.
Donor–acceptor aminocyclopropanes bearing both amino and carboxyl groups underwent catalytic asymmetric ring-opening reactions with diverse oxygen nucleophiles to afford chiral γ-oxygen-substituted γ-aminobutyric acid derivatives with good results.
A mild and efficient method for photoredox-catalyzed bromonitroalkylation of alkenes is described herein.
Organoborons have emerged as a class of privileged building blocks in modern organic synthesis, enabling unparalleled molecular diversity and serving as versatile carboxylic acid bioisosteres with profound implications in drug discovery.