Pyrazolopyridines have gained increasing attention in kinase-targeting anti-cancer drug discovery. This review analyzes the success stories wherein this bicycle was employed to address various challenges.
A general and convenient approach for the synthesis of biologically important pyrazolo[4,3-c]pyridines has been developed via amination of 5-acyl-4-pyridones with hydrazines.
The synthesis of fused N-heterocycles under microwave irradiation using HKUST-1 and evaluation of their in vitro biological activities.
In this study, two pyrazolo[3,4-b]pyridine derivatives (4a and 4b) were grown using a slow evaporation solution growth technique and characterized by FT-IR, HRMS, 1H/13C NMR spectroscopy, and X-ray crystallography.
Super fine Fe2O3 nanoparticles are confined inside the carbon shell and S-doping enables MOF-derived S0.15–Fe2O3@C nano-spindles to exhibit high-rate capability and low volume.