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Recent Advances in Synthetic Isoquinoline-Based Derivatives in Drug Design

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Molecules, 2025, 30, 4760
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An updated review on the role of small molecules in mediating protein degradation

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European Journal of Medicinal Chemistry, 2025, 287, 117370
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Li Zhang, Yulong Li, Yufeng Qian, Ruliang Xie, Wei Peng and Wen Zhou

Archiv der Pharmazie, 2025, 358
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ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation

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European Journal of Medicinal Chemistry, 2024, 270, 116387
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Highly Potent and Intestine Specific P‐Glycoprotein Inhibitor to Enable Oral Delivery of Taxol

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Angewandte Chemie, 2024, 136
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Di Gu, Jianhua Wang, Yuna Fu, Ruifeng Hao, Qiuyue Xie and Letian Zhang

European Journal of Pharmacology, 2026, 1015, 178546
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Synthesis and evaluation of novel tetrahydroisoquinoline-benzo[h]chromen-4-one conjugates as dual ABCB1/CYP1B1 inhibitors for overcoming MDR in cancer

Jinyun Dong, YuLong Li, Zhiyuan Jin, Zumei Wu, Maohua Cai, Guangzhao Pan, Wenchong Ye, Wen Zhou, Zheshen Li, Sichao Tian, Zhe-Sheng Chen and Jiang-Jiang Qin

Bioorganic & Medicinal Chemistry, 2024, 114, 117944
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Small molecule inhibitors targeting heat shock protein 90: An updated review

Yulong Li, Jinyun Dong and Jiang-Jiang Qin

European Journal of Medicinal Chemistry, 2024, 275, 116562
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Spiroindoline quinazolinedione derivatives as inhibitors of P-glycoprotein: potential agents for overcoming multidrug resistance in cancer therapy

Fatemeh Moosavi, Masoumeh Divar, Soghra Khabnadideh, Marjan Tavakkoli, Maryam Mohabbati, Luciano Saso, Alireza Poustforoosh and Omidreza Firuzi

Mol Divers, 2025, 29, 6519
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Ferroptosis Inducers Erastin and RSL3 Enhance Adriamycin and Topotecan Sensitivity in ABCB1/ABCG2-Expressing Tumor Cells

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IJMS, 2025, 26, 635
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European Journal of Medicinal Chemistry, 2025, 291, 117542
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Tumour-Derived Extracellular Vesicles in Chemotherapy Resistance: Molecular Pathways, Clinical Implications and Therapeutic Opportunities

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AJPS, 2025, 371
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Highly Potent and Intestine Specific P‐Glycoprotein Inhibitor to Enable Oral Delivery of Taxol

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Angew Chem Int Ed, 2024, 63
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