A candidate reference LC-MS/MS method was developed and validated for quantifying aldosterone in serum and 24 h urine. The method shows high accuracy and traceability, supporting the standardization of aldosterone measurements.
This review emphasizes the importance of integrating structural insights of current therapeutics with pharmacological tactics to accelerate development of new therapeutics targeting RAAS for improved and efficacious cardiovascular outcomes.
An accurate and precise analytical method (DSPE-LC-ID4-MS/MS) was proposed for the determination of selected hormones at trace levels.
Mass spectrometry imaging (MSI) has advanced from a niche technique to a widely applied spatial biology tool. This review highlights state-of-the-art MSI application in emerging and the six largest biomedical fields according to a set of criteria.
Boron supplementation in diets with varying calcium levels modulates bone development and bone parameters in mice by regulating calcium signaling, lipid metabolism, and neural signaling and inflammatory signaling.