We investigated the reaction mechanisms for BBr3 induced dibenzosilole-to-dibenzoborole transformation by DFT calculations and NMR analysis.
The direct mechanocatalytic Suzuki–Miyaura coupling reaction, utilizing palladium milling balls as active catalysts, was investigated regarding the physical state of the reagents and the reaction phase.
Highly regioselective and efficient synthesis of trisubstituted allenes with palladium catalysts via deaminative coupling reaction among tertiary propargylamines and arylsiloxanes which were activated in situ using Et3N·3HF has been developed.
A library of (teraryl, quateraryl, hexaryl) polyaryl unnatural amino acid motifs is generated via successive stereoselective C(sp3)–H arylation and Suzuki coupling. These molecules may be useful for future proteomimetic design (α-helix mimetics).
This study reports a Pd/NBE-catalyzed dehydrobicyclization of heteroaryl iodides using N-protected aryl carbamoyl chloride for acylation, enabling efficient synthesis of nitrogen-containing polycycles via direct C–H triple functionalization.