Yao Zhang, Fule Wu, Muneeb Ur Rehman and Sihui Long
RSC Med. Chem., 2026,17, 2197-2269
Abstract
This review comprehensively explores the design, synthesis, and pharmacological activities of carboline isomers reported between 2000 and 2025, with a particular emphasis on their key bioactivities, encompassing anticancer, neuroprotective, antiparasitic, and antimicrobial.
Sarat Chatterjee and Chinmay Chowdhury
Org. Biomol. Chem., 2025,23, 8841-8861
Abstract
In this review, we provide a brief yet comprehensive account of the metal-catalysed syntheses of four isomeric carbolines (α/β/γ/δ) along with the mechanistic pathways involved in the aforesaid strategies.
Rajni Lodhi, S Banuprakash Goud and Sampak Samanta
New J. Chem., 2024,48, 14163-14169
Abstract
Efficient access to α-carbolines was achieved via a domino reaction between iminoindoles and arylidene malononitriles using DABCO/NaHCO3 as a cooperative basic system. The synthesized scaffolds display blue emissions with good quantum yields.
Amisha Punmiya, Alka Raj Pandey and Amisha Vora
RSC Med. Chem., 2025,16, 4676-4697
Abstract
This review presents a detailed analysis of β-carbolines as promising multi-target antimalarial agents.
Wei Feng, Chao Zhang, Xinlin Zhou, Kuiyi You, Guo-Jun Deng and Shanping Chen
Org. Chem. Front., 2023,10, 5457-5462
Abstract
An I2O5-promoted chemoselective three-component tandem reaction of indole-3-carboxaldehydes, ammonium acetate, and alkynes for the construction of α-carbolines under metal-free conditions has been described.