A rhodium(III)-catalyzed indole C4-selective cyanation is described using the bench-stable, user-friendly electrophilic cyanation agent N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) as a coupling partner.
A catalytic protocol for the RhIII-promoted N-heteroarylation of 2-pyridones with N-heterocyclic boronates containing pyridines, pyrazoles, pyrimidine, quinoline, thiophene and furan has been disclosed via a removable pyridine auxiliary.
Nitrone-directed, transition metal-catalysed C–H activation reactions enable the design of cascade processes for the efficient assembly of complex, nitrogen-containing molecules.
This review covers sulfur-directed TM-catalyzed cascade C–H activations/cyclizations with alkynes and encompasses the literature mainly from 2012 to 2024.
Reported herein is a Rh(III)-catalyzed C–H cross-coupling of benzoxazinones and unactivated styrenes to furnish vinylarene scaffolds. Mechanistic studies, gram-scale experiment and further transformations of this method were also demonstrated.