In this study, a series of 13 new D-ring fused steroidal N(2)-substituted-1,2,3-triazoles were synthesized, characterized and evaluated for their biological activities.
Design, synthesis, photoswitching and computational studies of N-methyl arylazo-3,5-(di-2-pyridyl)pyrazoles and their N-alkyl pyridinium derivatives as probes for pH modulation.
Structures and enol–enol tautomerism of glutinosasins A–D, four novel 8,14-seco-ent-kaurane diterpenoids from Isodon glutinosus, were elucidated via quantum chemical calculations. Notably, glutinosasin D selectively inhibited SW480 tumor cells.
Base-mediated intermolecular macrocyclization and Rh- or Ni-catalyzed intramolecular double [2 + 2 + 2] cycloadditions allow enantio- and diastereoselective synthesis of planar chiral [2.2]triphenylenophanes.
The investigation of the excited state intramolecular double proton transfer process of 2,2′-(benzo[1,2-d:4,5-d′]bis(thiazole)-2,6-diyl)diphenol in DCM proposes a stepwise ESIDPT mechanism.