Nanoparticles incorporated hydrogels for delivery of antimicrobial agents: developments and trends

Naveed Ahmad, Syed Nasir Abbas Bukhari, Muhammad Ajaz Hussain, Hasan Ejaz, Muhammad Usman Munir and Muhammad Wahab Amjad

RSC Adv., 2024, 14, 13535
DOI: 10.1039/D4RA00631C

Silver incorporated SeTe nanoparticles with enhanced photothermal and photodynamic properties for synergistic effects on anti-bacterial activity and wound healing

Irfan Ullah, Shahin Shah Khan, Waqar Ahmad, Luo Liu, Ahmed Rady, Badr Aldahmash, Changyuan Yu and Yushu Wang

RSC Adv., 2024, 14, 18871
DOI: 10.1039/D4RA01343C

One pot synthesis of SeTe–ZnO nanoparticles for antibacterial and wound healing applications

Yushu Wang, Shahin Shah Khan, Irfan Ullah, Ahmed Rady, Badr Aldahmash, Yingjie Yu, Luo Liu and Xiulong Zhu

RSC Adv., 2025, 15, 3439
DOI: 10.1039/D4RA06594H

Multifunctional silver nanoparticle embedded eri silk cocoon scaffolds against burn wounds-associated infection

Paulami Dam, Shubhajit Shaw, Rittick Mondal, Joydeep Chakraborty, Trinankur Bhattacharjee, Ipsita Kumar Sen, Sanjeet Manna, Abdul Sadat, Supratim Suin, Hironmoy Sarkar, Yavuz Nuri Ertas and Amit Kumar Mandal

RSC Adv., 2024, 14, 26723
DOI: 10.1039/D4RA05029K

Beyond bone regeneration: Hydroxyapatite's emerging potential in advanced wound management

Li-Li Cao, Zhong-Feng Zhang, Jie Min, Dan Yuan, Jun-Yang Yu and Pei Yu

Materials Today Communications, 2025, 48, 113426
DOI: 10.1016/j.mtcomm.2025.113426

Nanomaterials in the Wound Healing Process: New Insights and Advancements

Tanikan Sangnim, Vivek Puri, Divya Dheer, D. Nagasamy Venkatesh, Kampanart Huanbutta and Ameya Sharma

Pharmaceutics, 2024, 16, 300
DOI: 10.3390/pharmaceutics16030300

Bioinspired xanthan gum hydrogel patch embedded with green synthesized CuO nanoparticles: A novel approach for antimicrobial, anticancer and in-vivo wound healing studies

D. Aashiba and A. Jepa Malar

Journal of the Indian Chemical Society, 2025, 102, 101824
DOI: 10.1016/j.jics.2025.101824

Calcium Hydroxyapatite in Its Different Forms in Skin Tissue Repair: A Literature Review

Paola Tatiana Espinosa Cruel, Camila Pascoal Correia dos Santos, Thalia Malave Cueto, Lisbeth Patricia Vasquez Avila, Daniela Vieira Buchaim and Rogerio Leone Buchaim

Surgeries, 2024, 5, 640
DOI: 10.3390/surgeries5030051

Biomedical prospects and challenges of metal dichalcogenides nanomaterials

Preeti Goswami, Videsh Kumar and Govind Gupta

Prog. Biomed. Eng., 2024, 6, 033001
DOI: 10.1088/2516-1091/ad6abb

A Comprehensive Review on Stimuli-Responsive Nanomaterials: Advancements in Wound Healing and Tissue Regeneration

M. Bellarmin, J. Nandhini, E. Karthikeyan, D. Mahalakshmi and K. K. Karthik

Biomedical Materials & Devices, 2025
DOI: 10.1007/s44174-025-00323-3

Prospects of Application of Silicon-Based Inorganic Hydrogels in Medicine and Cosmetology. A Review

E. V. Parfenyuk and E. S. Dolinina

Silicon, 2025, 17, 1503
DOI: 10.1007/s12633-025-03307-6

Antimicrobial hybrid coatings: A review on applications of nano ZnO based materials for biomedical applications

Prakash Monika, R. Hari Krishna, Zayaan Hussain, Krithika Nandhini, Samhitha J. Pandurangi, Tausif Malek and S. Girish Kumar

Biomaterials Advances, 2025, 172, 214246
DOI: 10.1016/j.bioadv.2025.214246

Mini Review: Challenges and Promising Advances in Hydrogel‐Based Scaffolds for Breast Tissue Regeneration

Jéssica de Lima Dias Boaventura Muniz, Anne Caroline da Silva Rocha and Lívia Rodrigues de Menezes

Polymers for Advanced Techs, 2024, 35
DOI: 10.1002/pat.6613

Innovative hydrogels in cutaneous wound healing: current status and future perspectives

Prasad Sawadkar, Ferdinand Lali, Elena Garcia-Gareta, Beatriz Gil Garrido, Abdullah Chaudhry, Priya Matharu, Christos Kyriakidis and Karin Greco

Front. Bioeng. Biotechnol., 2025, 13
DOI: 10.3389/fbioe.2025.1454903

Bletilla striata Polysaccharide-/Chitosan-Based Self-Healing Hydrogel with Enhanced Photothermal Effect for Rapid Healing of Diabetic Infected Wounds via the Regulation of Microenvironment

Kai Zhao, Zhengbo Hu, Xingcan Chen, Yuchi Chen, Mingyuan Zhou, Xiaoqing Ye, Fangmei Zhou, Bingqi Zhu and Zhishan Ding

Biomacromolecules, 2024, 25, 3345
DOI: 10.1021/acs.biomac.4c00013

Addressing the silent killer: Nanotechnology for preventing oral bacteria-induced cardiovascular risks

Santosh Mallikarjun Bhavi, Akshata Choudhari Padti, Bothe Thokchom, Sapam Riches Singh, Megha B. Abbigeri, Sudheendra Rao Kulkarni, Pooja Joshi, Shivanand S. Bhat, B. P. Harini and Ramesh Babu Yarajarla

Periodontal and Implant Res., 2025, 9
DOI: 10.1007/s41894-025-00145-y

Nanomaterial interventions for wound healing: Current status of preclinical and clinical studies

Garima Agarwal, Samir Bhargava and Shweta Dumoga

Wound Repair Regeneration, 2025, 33
DOI: 10.1111/wrr.70031

Guanosine and Deoxyinosine Structural Analogs Extracted from Chick Early Amniotic Fluid Promote Cutaneous Wound Healing

Mashaal Ahmad, Jia Yu, Sha Cheng, Zara Ahmad Khan, Yan Luo and Heng Luo

IJMS, 2023, 24, 12817
DOI: 10.3390/ijms241612817

Effect of Silica Nanoparticle Treatment on Adhesion between Tissue-like Substrates and In Vivo Skin Wound Sealing

Yeji Jeon, Tae Ryeol Kim, Eun Seo Park, Jae Hyun Park, Han Sung Youn, Dae Youn Hwang and Sungbaek Seo

JFB, 2024, 15, 259
DOI: 10.3390/jfb15090259

The role of light emitting diode in wound healing: A systematic review of experimental studies

Rebeca Barbosa da Rocha, Dakson Douglas Araújo, Fabrício dos Santos Machado, Vinicius Saura Cardoso, Ana Jérsia Araújo and José Delano Barreto Marinho‐Filho

Cell Biochemistry & Function, 2024, 42
DOI: 10.1002/cbf.4086

A critical overview of challenging roles of medicinal plants in improvement of wound healing technology

Deepika Pathak and Avijit Mazumder

DARU J Pharm Sci, 2024, 32, 379
DOI: 10.1007/s40199-023-00502-x

Efficacy of silver nanoparticle-modified bullfrog skin as an antimicrobial wound dressing

Carlos Augusto Zanoni Souto, Fernando Gomes de Souza, Kaushik Pal, José Teixeira de Seixas Filho, Helena Keiko Toma, Nidhi Asthana, Azmat Ali Khan and Sabiha Fatima

Journal of Molecular Structure, 2025, 1321, 139961
DOI: 10.1016/j.molstruc.2024.139961

Recent advances in mesoporous silica nanoparticles formulations and drug delivery for wound healing

Razieh Heidari, Vahideh Assadollahi, Mohammad Hossein Shakib Manesh, Seyed Abbas Mirzaei and Fatemeh Elahian

International Journal of Pharmaceutics, 2024, 665, 124654
DOI: 10.1016/j.ijpharm.2024.124654

Biodegradable multifunctional fabrication of silver-doped zinc oxide nanoparticle on chitosan/polyvinyl alcohol flexible film for effective antibacterial potential and attenuation of human liver carcinoma cells

Gowri Rengasamy, Dhilip Kumar Chinnalagu, Krithikapriya Chinniah and Sundrarajan Mahalingam

International Journal of Biological Macromolecules, 2025, 321, 146309
DOI: 10.1016/j.ijbiomac.2025.146309

Functionalization of gelatin films dressings with silver-doped zinc oxide nanoparticles for prevention of bacterial infection and promoting wound repair

Bahaa A. Hemdan, Samar A. El-Kholy, E. S. Shalaby, A. H. Abd-Al-Aleem, Tarek S. Aysha and Mehrez E. El-Naggar

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-13382-9

Hyaluronic acid and ZIF-8 nanocomposites for wound care

Chou-Yi Hsu, Saade Abdalkareem Jasim, Ebraheem Abdu Musad Saleh, Kakul Hussin Firoz, S. Renuka Jyothi, Debasish Shit, Priya Priyadarshini Nayak, Ashish Singh Chauhan, Dalya S. Obaida and Alireza Hashemzadeh

International Journal of Biological Macromolecules, 2025, 315, 144475
DOI: 10.1016/j.ijbiomac.2025.144475

Design a Coordinated Nano-Platform for Coumarin-Regulated Delivery in Line with the Biological Systems’ Growth Phases

Rojan Akhbarati, Rahebeh Amiri Dehkharghani and Soheila Zamanlui Benisi

J Polym Environ, 2025, 33, 990
DOI: 10.1007/s10924-024-03458-4

Bioactive hydrogels for wound Healing: Anti-Inflammatory mechanisms and nanomaterial Integration: A review

Ehsan Rahimpour, Atoosa Haghighizadeh, Mohammad Bagheri tabar, Delaram Molazemhoseini, Parisa Heydari, Armita Banimahdidehkordi and Roya Jahani

Journal of Drug Delivery Science and Technology, 2025, 113, 107385
DOI: 10.1016/j.jddst.2025.107385

Effective wound healing on diabetic mice by adhesive antibacterial GNPs-lysine composited hydrogel

Sureerat Khunmanee, Anseo Choi, Il Young Ahn, Woo Ju Kim, Tae Hui Bae, Shin Hyuk Kang and Hansoo Park

iScience, 2024, 27, 108860
DOI: 10.1016/j.isci.2024.108860

Injectable self-healing alginate/PEG hydrogels cross-linked via thiol-Michael addition bonds for hemostasis and wound healing

Yuxuan Xie, Guichen Li, Jun Wu, Jiachen Zhu, Xuemei Cai, Peizuo Zhao, Dan Zhang and Yuan Zhong

Carbohydrate Polymers, 2025, 348, 122864
DOI: 10.1016/j.carbpol.2024.122864

Nanosilver-loaded and polysaccharide-based biomaterial for antibacterial activity - in combination with photobiomodulation for effective wound healing applications

Sathish Sundar Dhilip Kumar, Nicolette Nadene Houreld and Heidi Abrahamse

Materials Letters, 2024, 363, 136293
DOI: 10.1016/j.matlet.2024.136293

Cellulose nanocrystal-based intelligent hydrogels: Innovations, challenges, and prospective application in advanced wound healing

Saah Siaffa Martin, Lu Gan, Lingli Zhang, Xurui Yang, Zhongbiao Tan, Hao Shi, Lingfeng Long and Hongliang Li

International Journal of Biological Macromolecules, 2025, 316, 144752
DOI: 10.1016/j.ijbiomac.2025.144752

An adhesive and self-healing ROS-scavenging hydrogel loading with hMSC-derived exosomes for diabetic wound healing

Yunting Zhang, Yihua Xu, Weitong Hu, Xiaolu Ma, Jingyi Hu, Yuxian Ye, Shengfei Yang, Yawei Yu, Ni Li, Dawei Zheng, Tianyuan Zhang, Hangjuan Lin and Jianqing Gao

International Journal of Pharmaceutics, 2025, 672, 125315
DOI: 10.1016/j.ijpharm.2025.125315

Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration

Amal George Kurian, Rajendra K. Singh, Varsha Sagar, Jung-Hwan Lee and Hae-Won Kim

Nano-Micro Lett., 2024, 16
DOI: 10.1007/s40820-024-01323-6

Synthesis of bimetallic oxides (SrO-CoO) nanoparticles decorated polyacrylamide hydrogels for controlled drug release and wound healing applications

Arfaa Sajid, Muniba Amjad, Qaisar Manzoor, Saba Wazir, Anam Sajid, Norah Alwadai, Munawar Iqbal and Nissren Tamam

International Journal of Biological Macromolecules, 2024, 274, 133194
DOI: 10.1016/j.ijbiomac.2024.133194

Advancement in nanotechnology-based formulations for cell repairment in burns

Dhiraj P. Sonje, Pravin S. Chinchole and Pravin Shende

Journal of Drug Delivery Science and Technology, 2025, 111, 107175
DOI: 10.1016/j.jddst.2025.107175

Green nanoscience for healthcare: Advancing biomedical innovation through eco-synthesized nanoparticle

Anjuman Ayub, Atif Khurshid Wani, Suhaib Mohd Malik, Mehvish Ayub, Reena Singh, Chirag Chopra and Tabarak Malik

Biotechnology Reports, 2025, e00913
DOI: 10.1016/j.btre.2025.e00913

Fabrication and evaluation of Dillenia indica-carrageenan blend hybrid superporous hydrogel reinforced with green synthesized MgO nanoparticles as an effective wound dressing material

Fahaduddin and Trishna Bal

International Journal of Biological Macromolecules, 2024, 265, 130835
DOI: 10.1016/j.ijbiomac.2024.130835

Advancements in nanocomposite hydrogels: a comprehensive review of biomedical applications

Gargee Baishya, Bandita Parasar, Manisha Limboo, Rupesh Kumar, Anindita Dutta, Anowar Hussain, Mayur Mausoom Phukan and Devabrata Saikia

Discov Mater, 2024, 4
DOI: 10.1007/s43939-024-00111-8

Polymer-Based Functional Materials Loaded with Metal-Based Nanoparticles as Potential Scaffolds for the Management of Infected Wounds

Xhamla Nqoro and Raymond Taziwa

Pharmaceutics, 2024, 16, 155
DOI: 10.3390/pharmaceutics16020155

Bioactive Curcuma aromatica-stabilized silver nanoparticles embedded chitosan dressing with improved antibacterial, anti-inflammatory, and wound healing properties

M.S. Tawre, A. Padhye, S. Chakraborty, N. Kulkarni, G. Bose, S. Mittal, U. Jadhav, S. Jadhav, J.M. Rajwade and K. Pardesi

Carbohydrate Polymer Technologies and Applications, 2024, 8, 100570
DOI: 10.1016/j.carpta.2024.100570

Nanostructure-assisted wound dressing materials: a literature review

P. S. Sharon Sofini, Kunal Biswas, Devadass Jessy Mercy, Agnishwar Girigoswami and Koyeli Girigoswami

Macromol. Res., 2024, 32, 1065
DOI: 10.1007/s13233-024-00291-5

Chitosan Nanoparticles: A Promising Candidate in Wound Healing

Masoumeh Askari, Amirhesam Keshavarz Zarjani, Ali Sayyahi, Raziye Badpa and Ali Naghizadeh

The International Journal of Lower Extremity Wounds, 2025
DOI: 10.1177/15347346251325057

Anti-infection and healing promotion of skin ECM hydrogel

Jinfeng Zhang

Cutaneous and Ocular Toxicology, 2025, 1
DOI: 10.1080/15569527.2025.2531039

Comparative In Vitro and In Silico Analyses of Phytochemicals From Butea monosperma for Wound-Healing Potential in Human Cells

Suraneni Venkata Dhruv Sudhakar Rao, Iadalin Ryntathiang, Archana Behera, Saantosh Saravanan, Monisha Prasad and Mukesh Kumar Dharmalingam Jothinathan

Cureus, 2024
DOI: 10.7759/cureus.62078

Polycaprolactone nanocapsule-loaded carbopol hydrogel enhances fusidic acid efficacy against Gram-negative bacteria and promotes wound healing

Amirah S. Alanazi, Rahaf M. Alanazi, Ayman Salama, Mona Qushawy, Mona F. Arafa, Nehal Elsherbiny, Huda M. Atif, Helal F. Hetta, Mohamed A. Safwat and Ghareb M. Soliman

International Journal of Pharmaceutics, 2025, 678, 125735
DOI: 10.1016/j.ijpharm.2025.125735

Lupeol: ethnopharmacological insights and therapeutic potential in human health

Achinta Singha, Anirban Chakraborty and Samir Kumar Sil

3 Biotech, 2025, 15
DOI: 10.1007/s13205-025-04325-2

Biopolymer based nanoparticles and their therapeutic potential in wound healing – A review

Mohit Kumar, Syed Mahmood, Shruti Chopra and Amit Bhatia

International Journal of Biological Macromolecules, 2024, 267, 131335
DOI: 10.1016/j.ijbiomac.2024.131335

Insights into electrospun polymeric nanofiber mats: an innovative dressing for wound healing applications

Bimal Rajchal, Yub Narayan Thapa, Deepshikha Karki, Prabha Prajapati and Rameshwar Adhikari

Polymer International, 2025, 74, 391
DOI: 10.1002/pi.6736

Chitosan-based composite scaffolds for accelerated epidermal-dermal wound healing

Athira S. Dev, Neethu Mohan and Renu Mohan

Explor BioMat-X, 2025, 2
DOI: 10.37349/ebmx.2025.101336

Silk fibroin-based scaffolds for wound healing applications with metal oxide nanoparticles

Denisa-Maria Radulescu, Ecaterina Andronescu, Otilia Ruxandra Vasile, Anton Ficai and Bodgan Stefan Vasile

Journal of Drug Delivery Science and Technology, 2024, 96, 105689
DOI: 10.1016/j.jddst.2024.105689

Antibacterial properties of photo-crosslinked chitosan/methacrylated hyaluronic acid nanoparticles loaded with bacitracin

Raquel R. Gonçalves, Daniela Peixoto, Rui R. Costa, Albina R. Franco, Vânia I.B. Castro, Ricardo A. Pires, Rui L. Reis, Iva Pashkuleva, Devid Maniglio, Annalisa Tirella, Antonella Motta and Natália M. Alves

International Journal of Biological Macromolecules, 2024, 277, 134250
DOI: 10.1016/j.ijbiomac.2024.134250

Wound Dressing Materials: Bridging Material Science and Clinical Practice

Maria Pia Ferraz

Applied Sciences, 2025, 15, 1725
DOI: 10.3390/app15041725

Nanotechnology at the Crossroads: Advancements and Ethical Dilemmas in Healthcare, Environment and Agriculture

Sumaira Anjum, Amna Komal Khan, Iqra Attique and Zahra Tariq

NANO, 2024, 19
DOI: 10.1142/S1793292024300111