ZIF-8-coated ZnO with pH-responsive natamycin release boosting the antifungal and anti-inflammation activity to treat fungal keratitis

Ziyi Wang, Jing Lin, Qian Wang, Lina Zhang, Bing Yu, Menghui Chi, Xueyun Fu, Daohao Li, Guiqiu Zhao and Cui Li

J. Mater. Chem. B, 2025, 13, 8406
DOI: 10.1039/D5TB00802F

Self-healing and shape-adaptive nanocomposite hydrogels with anti-inflammatory, antioxidant, antibacterial activities and hemostasis for real-time visual regeneration of diabetic wounds

Nuoya Zhao and Weizhong Yuan

Composites Part B: Engineering, 2023, 262, 110819
DOI: 10.1016/j.compositesb.2023.110819

Injectable and pH-Responsive Metformin-Loaded Hydrogel for Active Inhibition of Posterior Capsular Opacification

Chao Yin, Yue Zhang, Cong Fan, Jun Zheng, Yu Yang, Yi Zhang and Jian Jiang

ACS Appl. Mater. Interfaces, 2024, 16, 59880
DOI: 10.1021/acsami.4c13318

Shikonin treats Aspergillus fumigatus keratitis by activating autophagy and reducing fungal load

Xuguang Yang, Fan Cong, Lingwen Gu, Qian Wang, Lina Zhang, Jing Lin, Weichen Liu, Xiaofeng Yao, Cui Li and Guiqiu Zhao

Experimental Eye Research, 2025, 259, 110569
DOI: 10.1016/j.exer.2025.110569

The preparation and therapeutic effects of β-glucan-specific nanobodies and nanobody-natamycin conjugates in fungal keratitis

Xing Liu, Jianxin Sui, Cui Li, Qian Wang, Xudong Peng, Fanyue Meng, Qiang Xu, Nan Jiang, Guiqiu Zhao and Jing Lin

Acta Biomaterialia, 2023, 169, 398
DOI: 10.1016/j.actbio.2023.08.019

Simultaneous Rosiglitazone Release and Low-Density Lipoprotein Removal by Chondroitin Sodium Sulfate/Cyclodextrin/Poly(acrylic acid) Composite Adsorbents for Atherosclerosis Therapy

Yujie Xiao, Yinghui Xu, Xianda Liu, Shengjun Cheng, Ran Wei, Weifeng Zhao and Changsheng Zhao

Biomacromolecules, 2024, 25, 3141
DOI: 10.1021/acs.biomac.4c00241

Identification and Characterization of Marine Bacteria-Derived Chondroitinase CHa3 in the PL35 Family

Wenwen Wang, Zeting Ning, Yameng Zhu, Bohan Zeng, Xiaoyun Li, Chunni Wu, Yanzi Dong, Yuqing Li, Mengda Zhang, Jinhua Zheng, Bo Lian, Hongyan Qiu, Huanhuan Wang, Danrong Lu and Qingdong Zhang

J. Agric. Food Chem., 2025, 73, 12887
DOI: 10.1021/acs.jafc.5c01795

Targeted Delivery of Celastrol via Chondroitin Sulfate Derived Hybrid Micelles for Alleviating Symptoms in Nonalcoholic Fatty Liver Disease

Yi Pan, Yunxiao Zhang, Hongling Ouyang, Tao Gong, Zhirong Zhang, Xi Cao and Yao Fu

ACS Appl. Bio Mater., 2023, 6, 4877
DOI: 10.1021/acsabm.3c00612

Multifunctional natamycin modified chondroitin sulfate eye drops with anti-inflammatory, antifungal and tissue repair functions possess therapeutic effects on fungal keratitis in mice.

Xue Tian, Lu Zhan, Xiaojing Long, Jing Lin, Yingxue Zhang, Junjie Luan, Xudong Peng and Guiqiu Zhao

International Journal of Biological Macromolecules, 2024, 279, 135290
DOI: 10.1016/j.ijbiomac.2024.135290

Oxymatrine mitigates Aspergillus fumigatus keratitis by suppressing fungal activity and restricting pyroptosis

Weichen Liu, Xue Tian, Lingwen Gu, Bing Yu, Ziyi Wang, Menghui Chi, Jing Lin, Qian Wang, Guibo Liu, Guiqiu Zhao and Cui Li

Experimental Eye Research, 2024, 240, 109830
DOI: 10.1016/j.exer.2024.109830

Thermo and LDL-responsive acrylated β-cyclodextrin based microspheres enable targeted oleanolic acid release and LDL removal for atherosclerosis therapy

Yujie Xiao, Xianda Liu, Ziyue Ling, Shifan Chen, Ran Wei, Weifeng Zhao and Changsheng Zhao

Chemical Engineering Journal, 2026, 530, 173689
DOI: 10.1016/j.cej.2026.173689

Pentoxifylline treats Aspergillus fumigatus keratitis by reducing fungal burden and suppressing corneal inflammation

Menghui Chi, Lingwen Gu, Lina Zhang, Jing Lin, Qiang Xu, Nan Jiang, Yuwei Wang, Yinghe Qi, Weilin Diao, Wendan Yi, Guiqiu Zhao and Cui Li

European Journal of Pharmacology, 2023, 945, 175607
DOI: 10.1016/j.ejphar.2023.175607

Plumbagin inhibits fungal growth, HMGB1/LOX-1 pathway and inflammatory factors in A. fumigatus keratitis

Fan Cong, Lingwen Gu, Jing Lin, Guibo Liu, Qian Wang, Lina Zhang, Menghui Chi, Qiang Xu, Guiqiu Zhao and Cui Li

Front. Microbiol., 2024, 15
DOI: 10.3389/fmicb.2024.1383509