1000 fold Ultra‐Photosensitized Fluorescent Protein Mimics Toward Photocatalytic Proximity Labeling and Proteomic Profiling Functions

Rui Sun, Yanan Huang, Huan Feng, Nan Zhao, Wang Wan, Di Shen, Bowen Zhong, Yukui Zhang, Xin Zhang, Qun Zhao, Lihua Zhang and Yu Liu

Advanced Science, 2025, 12
DOI: 10.1002/advs.202413063

A hydrophobic photouncaging reaction to profile the lipid droplet interactome in tissues

Di Shen, Qun Zhao, Huaiyue Zhang, Ci Wu, Hao Jin, Kun Guo, Rui Sun, Hengke Guo, Qi Zhao, Huan Feng, Xuepeng Dong, Zhenming Gao, Lihua Zhang and Yu Liu

Proc. Natl. Acad. Sci. U.S.A., 2025, 122
DOI: 10.1073/pnas.2420861122

Photocatalytic proximity labeling coupled with cross-linking for deciphering of the lysosome proteome in living cells

He Wang, Zichun Qiao, Lihua Zhang, Bo Jiang and Yukui Zhang

Analytica Chimica Acta, 2025, 1379, 344737
DOI: 10.1016/j.aca.2025.344737

Catalysis in Chemical Modification of Proteins

Seiya Ishizawa, Koki Fujimura, Kounosuke Oisaki, Shinichi Sato and Jun Ohata

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202402125

Mitochondria-Associated Transcriptome Profiling via Localizable Aggregation-Induced Emission Photosensitizers in Live Cells

Jiying Liang, Jinghua Han, Yuan Zhuang, GuanHua Chen and Ying Li

ACS Chem. Biol., 2024, 19, 419
DOI: 10.1021/acschembio.3c00617

Deep Bottom-up Proteomics Enabled by the Integration of Liquid-Phase Ion Trap

Xinyan Fu, Jie Hong, Yanbing Zhai, Kefu Liu and Wei Xu

Anal. Chem., 2023, 95, 10137
DOI: 10.1021/acs.analchem.3c00532

Profiling of the Golgi Apparatus Proteome in Living Cells Using Nanophotosensitizer-Mediated Photocatalytic Proximity Labeling

Shuxian Wei, He Wang, Zichun Qiao, Qianqian Jiang, Jianbo Qu and Bo Jiang

Anal. Chem., 2026, 98, 9531
DOI: 10.1021/acs.analchem.5c02400

A Cell‐Permeable Photosensitizer for Selective Proximity Labeling and Crosslinking of Aggregated Proteome

Huan Feng, Qun Zhao, Nan Zhao, Zhen Liang, Yanan Huang, Xin Zhang, Lihua Zhang and Yu Liu

Advanced Science, 2024, 11
DOI: 10.1002/advs.202306950

Near-Infrared Light-Mediated Living Cells Mitochondrial Proteome Proximity Labeling

Yuqi Zeng, Zichun Qiao, He Wang, Bo Gao, Qianqian Jiang, Yukui Zhang, Lihua Zhang and Bo Jiang

Anal. Chem., 2025, 97, 4287
DOI: 10.1021/acs.analchem.4c06453

Energy-transfer photoproximity labelling in live cells using an organic cofactor

Leander B. Crocker, Jan Vincent V. Arafiles, Judith M. Müchler, Max Ruwolt, Kristin Kemnitz-Hassanin, Kilian Roßmann, Christian E. Stieger, Fan Liu, Nataliya Archipowa, Roger Jan Kutta and Christian P. R. Hackenberger

Nat. Chem., 2025, 17, 1928
DOI: 10.1038/s41557-025-01931-8

Photocatalytic Structures for Protein Modifications

Zhengyi Liu, Yasunori Okamoto and Shinichi Sato

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202301424

Ionic‐Fence Effect in Au Nanoparticle‐Loaded UiO‐66 Metal–Organic Frameworks for Highly Chemoselective Hydrogenation

Yicheng Zhong, Peisen Liao, Pingping Jiang, Yuhao Zhang, Jiawei Kang, Sizhuo Xie, Rongyu Feng, Yanan Fan, Qinghua Liu and Guangqin Li

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202501821

Small‐Molecule Benzo‐Phenoselenazine Derivatives for Multi‐Subcellular Biomolecule Profiling

Han Jia, Jinghua Han, Yajing Qi, Jie Liu, Yuen Ting Leung, Yau Hei Tung, Yuanyuan Chu, Tong Wang, Yi‐Man Eva Fung, Yi Wang and Ying Li

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202419904

Dexter Energy Transfer Photocatalytic Microdissection of Amyloid Plaques in Alzheimer’s Disease

Rui Sun, Jintai Deng, Di Shen, Jing Yan, Yanan Huang, Huan Feng, Man Li, Yusong Ge, Xin Zhang and Yu Liu

JACS Au, 2026, 6, 1129
DOI: 10.1021/jacsau.5c01509

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

Shinichi Sato, Kazuki Miura, Juki Nakao and Hiroyuki Nakamura

The Chemical Record, 2026
DOI: 10.1002/tcr.70180

Intracellular Photocatalytic Proximity Labeling (iPPL) for Dynamic Analysis of Chromatin-Binding Proteins Targeting Histone H3

Kazuki Miura, Hikaru Niimi, Tatsuya Niwa, Hideki Taguchi and Hiroyuki Nakamura

ACS Chem. Biol., 2024, 19, 2412
DOI: 10.1021/acschembio.4c00680

Intracellular Catalytic Photooxygenation of α‐Synuclein Amyloid

Atsushi Iwai, Youhi Hwang, Hiroki Umeda, Taka Sawazaki, Ikumi Tomizawa, Maiko Ono, Makoto Higuchi, Youhei Sohma, Yukiko Hori, Taisuke Tomita, Harunobu Mitsunuma and Motomu Kanai

ChemistryEurope, 2026, 4
DOI: 10.1002/ceur.202500192

Small‐Molecule Benzo‐Phenoselenazine Derivatives for Multi‐Subcellular Biomolecule Profiling

Han Jia, Jinghua Han, Yajing Qi, Jie Liu, Yuen Ting Leung, Yau Hei Tung, Yuanyuan Chu, Tong Wang, Yi‐Man Eva Fung, Yi Wang and Ying Li

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202419904

Exosomal miR-27a-5p inhibits indoxyl sulfate-induced cardiac dysfunction by targeting the USF2/FUT8 axis

Kun Xiao, Jiaojiao Hao, Nan Wang, Nan Shen, Bo Jiang, Longkai Li, Xu Zhang, Weidong Wang, Hui He, Ziran Wang, Huiyi Song, Qingzhu Tang, Biaojie Qin, Xiangning Du, Fan Yang, Shuni Chen, Xianan Guo, Shuang Meng and Hongli Lin

Free Radical Biology and Medicine, 2025, 241, 268
DOI: 10.1016/j.freeradbiomed.2025.09.040

Chemical and Biological Strategies for Profiling Protein‐Protein Interactions in Living Cells

You‐Yu Wang, Wenyi Li, Bang‐Ce Ye and Xiao‐Bao Bi

Chemistry An Asian Journal, 2023, 18
DOI: 10.1002/asia.202300226

Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins

Hiroki Umeda, Taka Sawazaki, Masahiro Furuta, Takanobu Suzuki, Shigehiro A. Kawashima, Harunobu Mitsunuma, Yukiko Hori, Taisuke Tomita, Youhei Sohma and Motomu Kanai

ACS Chem. Neurosci., 2023, 14, 2710
DOI: 10.1021/acschemneuro.3c00264

Silicon-rhodamine-enabled identification for near-infrared light controlled proximity labeling in vitro and in vivo

Wenjing Wang, Hongyang Guo, Xiaosa Yan, Xuanzhen Pan, Xiaofei Wang, Yiming Rong, Zexiao Bai, Liwan Zhang, Zhaofa Wu, Xinyu Zhao, Weiren Huang, Wei Qin and Ling Chu

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-63496-x

Recent advances in spatial proteomics by super-resolution proximity labeling

Dong-Gi Jang and Jong-Seo Kim

Current Opinion in Chemical Biology, 2026, 93, 102689
DOI: 10.1016/j.cbpa.2026.102689

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen and Kun Qian

VIEW, 2026, 7
DOI: 10.1002/VIW.20250171

Multiprobe Photoproximity Labeling of the EGFR Interactome in Glioblastoma Using Red-Light

Feifei Tong, Wuyue Zhou, Michalina Janiszewska and Ciaran P. Seath

J. Am. Chem. Soc., 2025, 147, 9316
DOI: 10.1021/jacs.4c15537

Revealing protein trafficking by proximity labeling-based proteomics

Yankun Wang and Wei Qin

Bioorganic Chemistry, 2024, 143, 107041
DOI: 10.1016/j.bioorg.2023.107041

Proximity labeling in neuroscience: decoding molecular landscapes for precision neurology

Xia Gao, Jianjun Lu, Peipei Chen, Xinna Wang, Longlong Zheng, Yuyin Shao, Huali Shen and Qian Yang

Transl Neurodegener, 2026, 15
DOI: 10.1186/s40035-026-00534-8

Ionic‐Fence Effect in Au Nanoparticle‐Loaded UiO‐66 Metal–Organic Frameworks for Highly Chemoselective Hydrogenation

Yicheng Zhong, Peisen Liao, Pingping Jiang, Yuhao Zhang, Jiawei Kang, Sizhuo Xie, Rongyu Feng, Yanan Fan, Qinghua Liu and Guangqin Li

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202501821