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Valence state engineering in multi-heteroatom-doped PAHs: a strategy for tunable photophysical properties and phototheranostic potentials

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Plasmon enhanced catalysis-driven nanomotors with autonomous navigation for deep cancer imaging and enhanced radiotherapy

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Suppressing ACQ of molecular photosensitizers by distorting the conjugated-plane for enhanced tumor photodynamic therapy

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Tumor microenvironment and Fe3+-triggered croconium nanoplatform for precise tumor location and combined type I photodynamic and photothermal amplified therapy

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Small‐Molecule Phototheranostic Agent with Extended π‐Conjugation for Efficient NIR‐II Photoacoustic‐Imaging‐Guided Photothermal Therapy

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Microenvironment-Triggered Signal Amplification for Dual-Modal Fluorescence/MRI of Hepatocellular Carcinoma

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Multimodal phototherapy agents target lipid droplets for near-infrared imaging-guided type I photodynamic/photothermal therapy

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Embedding linear rotors into cyanine scaffolds for photostable, viscosity-responsive AIE probes toward pathology-relevant biological imaging

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Recent advances in NIR-II fluorescence/photoacoustic dual-modality imaging probes

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Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

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Well-tailored Photosensitizers with Boosted Type-I ROS Generation by Fluorination Strategy for Precise Near-infrared Fluorescence-guided Photodynamic Therapy

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Journal of Photochemistry and Photobiology B: Biology, 2023, 245, 112748
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Controllable Self‐Assembly of V═O Metalloradical Complex with Intramolecular Charge Transfer for Enhanced NIR‐II Fluorescence Imaging‐Guided Photothermal Therapy

Jianshuai Bao, Zengyin Li, Deliang Wang, Jiefei Wang, Guan Huang, Jianlei Qian, Xiaoyan Yang, Peng‐Cheng Duan, Sheng Zhang, Feng Bai and Yong Zhong

Adv Healthcare Materials, 2025, 14
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Electrostatic Co‐Assembly of Cyanine Pair for Augmented Photoacoustic Imaging and Photothermal Therapy

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Intratumor delivery of amino-modified graphene oxide as a multifunctional photothermal agent for efficient antitumor phototherapy

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Efficient radical generator with NIR emission by donor modulation for mitochondria-targeted photodynamic therapy

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(E)-8-(4-(4-(Diphenylamino)styryl)phenoxy)-N,N,N-trimethyloctan-1-aminium Bromide

Saiya Yang, Ya-Na Wang, Yuyang Ma, Ruirui Li, Maxwell Ampomah-Wireko, Cedric Dzidzor Kodjo Amengor, En Zhang and Yi-Hong Zhao

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Donor-engineered and H-aggregated squaraine-nanoprobe triggering tumor NIR-II fluorescence imaging with larger Stokes shift and type I photodynamic/photothermal synergistic therapy

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Charge-Reversal Near-Infrared II Polymeric Amphiphiles Enable Efficient Combinatorial Gene and Mild Photothermal Therapy for Osteosarcoma

Fang Tang, Xiaoyu Zhang, Zhenqi Liu, Aojie Liu, Hairui Liu, Shi Ding, Yajie Lu, Hua Bai, Aixiang Ding, Jing Li and Lin Li

ACS Nano, 2026, 20, 4648
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Engineering Simple Type I AIE Photosensitizer via Donor and π‐Bridge Modulations for NIR‐II Imaging‐Guided Photodynamic and Photothermal Therapy

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Dual‐Pronged Attack: pH‐Driven Membrane‐Anchored NIR Dual‐Type Nano‐Photosensitizer Excites Immunogenic Pyroptosis and Sequester Immune Checkpoint for Enhanced Prostate Cancer Photo‐Immunotherapy

He Wang, Zhangxin He, Yijian Gao, Dexiang Feng, Xuedong Wei, Yuhua Huang, Jianquan Hou, Shengliang Li and Weijie Zhang

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NIR-II AIEgens for Phototheranostics: Design, Applications and Perspectives

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Acidic Lysosome-Anchoring Croconium-Based Nanoplatform for Enhanced Triple-Mode Bioimaging and Fe3+-Triggered Tumor Synergistic Therapy

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An Asymmetric NIR-II Organic Fluorophore with an Ultra-Large Stokes Shift for Imaging-Guided and Targeted Phototherapy

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Remote Control of Energy Transformation‐Based Cancer Imaging and Therapy

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Dual Key‐Activated Nir‐I/II Fluorescence Probe for Monitoring Photodynamic and Photothermal Synergistic Therapy Efficacy

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Recent Advances in Strategies to Enhance Photodynamic and Photothermal Therapy Performance of Single‐Component Organic Phototherapeutic Agents

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Long wavelength AIE enzyme prodrug-photosensitizer with dual cationic structure for fluorescence imaging of tumor cells and synergistic photodynamic therapy

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Image‐Guided Photothermal and Immune Therapy of Tumors via Melanin‐Producing Genetically Engineered Bacteria

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Reversible Chemistry for Cancer Therapy and Diagnosis

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Dual/Multi-Modal Image-Guided Diagnosis and Therapy Based on Luminogens with Aggregation-Induced Emission

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Conjugated Polymer for NIR-II Phototheranostics toward Tumor

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Simultaneously Enhancing NIR‐II Emission, Type‐I, and Type‐II Photosensitization Through Acceleration of Charge‐Separated‐State Formation for Tumor Phototheranostics

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Quantitative Near-Infrared Photoacoustic Imaging of Gamma-Glutamyl Transpeptidase Activity in Tumors

Yueyan Yang, Rui Wang, Xinrun Jin, Wenying Zhong and Lei Zhou

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Molecular and nanoparticulate agents for photodynamic therapy guided by near infrared imaging

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Metabolic Regulation of Biosynthesis of Melanin Nanoparticles for Enhancing Photothermal Therapy of Breast Tumor

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Recent advances in the design and applications of near-infrared II responsive small molecule phototherapeutic agents

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Progress and trends in PET/NIRF-based dual-modality imaging probes

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A D-π-A-π-D-architectured cell membrane-targeted Type I photosensitizer for cervical cancer photodynamic therapy

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A Dual‐Function Hemicyanine Material with Highly Efficient Photothermal and Photodynamic Effect Used for Tumor Therapy

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Aggregation‐Enhanced Asymmetric Heptamethine Cyanine Nanoplatform for Imaging‐Guided Synergistic Phototherapy and Ferroptosis

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High‐Performance NIR‐II Fluorescent Type I/II Photosensitizer Enabling Augmented Mild Photothermal Therapy of Tumors by Disrupting Heat Shock Proteins

Quanheng Jiang, Jingyu Li, Zhong Du, Mengyuan Li, Liying Chen, Xunwen Zhang, Xialian Tang, Yaowei Shen, Dalong Ma, Wen Li, Lin Li, Nuernisha Alifu, Qinglian Hu and Jie Liu

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Tuning Photophysical Conflict Into Synergy: Stereoelectronic Planarity Disruption Unlocks Concurrent Aggregation‐Enhanced ROS and NIR‐II Fluorescence

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Precise Preparation of Supramolecular Spherical Nucleic Acids for Nucleolin‐Targeted Gene Delivery

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Crucial Role of Trigonal Pyramidal and Rigid Planar Donors in Croconaine Nanoprobe for Tumor NIR-II Fluorescence Imaging and High-Efficiency Phototherapy

Chengren Ouyang, Haixin Teng, Guanrong Ou, Jielin Yu, Qiuke Huang and Chun-Qiong Zhou

ACS Appl. Mater. Interfaces, 2026
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AIEgens: An Exemplary Template for “One‐for‐All” Multimodal Phototheranostics

Miaomiao Kang, Xue Li, Shuaiyin Zhang, Hao Yang, Caifa You, Yuxun Ding, Chunying Fu, Zhijun Zhang, Dong Wang and Ben Zhong Tang

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Uniting Dual‐Modal MRI/Chemiluminescence Nanotheranostics: Spatially and Sensitively Self‐Reporting Photodynamic Therapy in Oral Cancer

Yining Tao, Chenxu Yan, Yue Wu, Dan Li, Juan Li, Yuchen Xie, Yingsheng Cheng, Yisheng Xu, Kai Yang, Wei‐Hong Zhu and Zhiqian Guo

Adv Funct Materials, 2023, 33
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Water‐Soluble Fe(II) Complexes for Theranostic Application: Synthesis, Photoacoustic Imaging, and Photothermal Conversion

Maeva Delcroix, Anil Reddy Marri, Stéphane Parant, Philippe C. Gros and Mathilde Bouché

Eur J Inorg Chem, 2023, 26
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Side-Chain Sulfonation to Modulate Hydroxyl Radical Generators for Efficient Suppression of Hepatoma Cells under Hypoxia

Shouchi Ji, Junjun Wang, Lixin Ma, Guiyan Xu, Ting Wang, Xuan Zhao, Yingyong Ni, Shengyu Shi and Hongping Zhou

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Self‐Aggregated Carbon Dots Enable High‐Contrast NIR‐II In Vivo Bioimaging

Shengli Guo, Wenkai Liu, Chengyuan Lv, Jianwei Li, Mingwang Yang, Jianjun Du, Jiangli Fan and Xiaojun Peng

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Synthesis of heavy-atom-free thienoisoindigo dye as near-infrared photosensitizer for type I photodynamic therapy and photoacoustic imaging

Feng Zhang, Hao Cai, Leichen Wang and Jinjun Shao

Journal of Photochemistry and Photobiology B: Biology, 2024, 261, 113052
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2, 1, 3‐Benzothiadiazole Derivative Small Molecule Fluorophores for NIR‐II Bioimaging

Zhen Hu, Lili Feng and Piaoping Yang

Adv Funct Materials, 2024, 34
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Triphenylamine-AIEgens photoactive materials for cancer theranostics

Junjie Wang, Yan Wang, Zhengdong Li, Changqiang Xie, Musammir Khan, Xingzhou Peng and Fabiao Yu

Chinese Chemical Letters, 2024, 35, 108934
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Theoretical Study on Spectrum and Luminescence Mechanism of Cy5.5 and Cy7.5 Dye Based on Density Functional Theory (DFT)

Zhao Liu, Xv Meng, Zhengze Zhang, Runzhang Liu, Shutao Wang and Jun-Qiang Lei

J Fluoresc, 2023, 35, 335
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Synthesis and photo-induced anticancer activity of new 2-phenylethenyl-1H-benzo[e]indole dyes

Gabrielė Varvuolytė, Eva Řezníčková, Sonata Krikštolė, Rasa Tamulienė, Aurimas Bieliauskas, Lukáš Malina, Veronika Vojáčková, Zdenko Duben, Hana Kolářová, Neringa Kleizienė, Eglė Arbačiauskienė, Asta Žukauskaitė, Vladimír Kryštof and Algirdas Šačkus

European Journal of Medicinal Chemistry, 2024, 277, 116777
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HSA shrinkage optimizes the photostability of embedded dyes fundamentally to amplify their efficiency as photothermal materials

Yongkang Yue, Zhou Xu, Kaiqing Ma, Fangjun Huo, Xuemei Qin, Kuanshou Zhang and Caixia Yin

Chinese Chemical Letters, 2024, 35, 109223
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Precise Preparation of Supramolecular Spherical Nucleic Acids for Nucleolin‐Targeted Gene Delivery

Ming Chen, Siyuan Miao, Yaqi Zhang, Xueman Chang, Jun Dai, Chuxin Chen, Shaoguang Li, Hui Li and Fan Xia

Angew Chem Int Ed, 2024, 63
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Water-Soluble Small Organic Fluorophores for Oncological Theragnostic Applications: Progress and Development

Ashanul Haque, Khalaf M. Alenezi, Abdulmohsen Khalaf Dhahi Alsukaibi, Ahmed A. Al-Otaibi and Wai-Yeung Wong

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Dual‐acceptor engineering of donor‐acceptor type molecules for all‐round boosting anti‐tumor phototherapy

Hua Gu, Wen Sun, Jianjun Du, Jiangli Fan and Xiaojun Peng

Smart Molecules, 2024, 2
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Simultaneously Enhancing NIR‐II Emission, Type‐I, and Type‐II Photosensitization Through Acceleration of Charge‐Separated‐State Formation for Tumor Phototheranostics

Yaru Lu, Yuchen Song, Yajing Jiang, Min Li, Zhengyumeng Zhu, Jucai Gao, Leilei Shi, Yu Tian, Dugang Chen, Duo Mao, Fang Hu and Wenbo Wu

Angew Chem Int Ed, 2026, 65
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Development of small-molecule NIR-II photothermal agents for image-guided tumor therapy

Long He, Yi Li, Chonghua Zhang, Xingxing Zhang, Benhua Wang, Tianbing Ren and Lin Yuan

Coordination Chemistry Reviews, 2025, 533, 216549
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Conjugated di-Cy5.5 derivative achieving strong light-harvesting ability beyond 808 nm for high-efficient antitumor photodynamic therapy

Hua Gu, Juan Zhang, Puan Yuan, Zhongyue Zheng, Wenkai Liu, Xiang Xia, Wen Sun, Jianjun Du, Jiangli Fan and Xiaojun Peng

Chinese Chemical Letters, 2026, 37, 111119
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