Nanozymes as next-generation ROS scavengers: design strategies, catalytic mechanisms, and therapeutic frontiers

Junxue Shen, Yalong Pan, Lijun Han, Li Luo, Taolei Sun and Yao Yu

J. Mater. Chem. B, 2025, 13, 8286
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Advances in oxygenation nanozymes for overcoming diabetic ulcers

Sumi Choi, Minjeong Kim, Minjin Kim and Su-Hwan Kim

Biomater. Sci., 2025, 13, 3498
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New facets of nanozyme activity of ceria: lipo- and phospholipoperoxidase-like behaviour of CeO2 nanoparticles

Madina M. Sozarukova, Elena V. Proskurnina, Anton L. Popov, Alexander L. Kalinkin and Vladimir K. Ivanov

RSC Adv., 2021, 11, 35351
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How the surface chemical properties of nanoceria are related to its enzyme-like, antiviral and degradation activity

Jiří Henych, Martin Šťastný, Jakub Ederer, Zuzana Němečková, Aleksandra Pogorzelska, Jakub Tolasz, Martin Kormunda, Petr Ryšánek, Barbara Bażanów, Dominika Stygar, Karel Mazanec and Pavel Janoš

Environ. Sci.: Nano, 2022, 9, 3485
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Recent advances in nanozymes for organophosphorus pesticide detection in food

Xueer Lin, Yanyan Huang, Jiahui Zou, Guancheng Zhu, Linfeng Pang and Yuqi Chen

Chem. Commun., 2025
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Modelling hydrogen peroxide adsorption on cerium dioxide: the effect of surface strain

Sidra Munir, Thomas Smith, Khoa Minh Ta, Lisa J. Gillie, David J. Cooke and Marco Molinari

Catal. Sci. Technol., 2025, 15, 5150
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Cholesterol oxidase-immobilized MXene/sodium alginate/silica@n-docosane hierarchical microcapsules for ultrasensitive electrochemical biosensing detection of cholesterol

Meng Zhang, Huan Liu and Xiaodong Wang

J. Mater. Chem. B, 2023, 11, 1506
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An antioxidant nanodrug protects against hepatic ischemia–reperfusion injury by attenuating oxidative stress and inflammation

Shuai Zhang, Yue Cao, Bo Xu, Hao Zhang, Songtao Zhang, Jian Sun, Ying Tang and Yinghui Wang

J. Mater. Chem. B, 2022, 10, 7563
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Ceria Nanoparticle Systems Alleviate Degenerative Changes in Mouse Postovulatory Aging Oocytes by Reducing Oxidative Stress and Improving Mitochondrial Functions

Danmei Zhang, Lingcun Ji, Yiran Yang, Jing Weng, Yanmin Ma, Lingyan Liu and Wei Ma

ACS Nano, 2024, 18, 13618
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Hybrid Se/melanin-like nanoparticles as ROS quenchers and inhibitors of amyloid aggregation

Giulio Pota, Concetta Di Natale, Antonia Puzone, Antonella Cascone, Sara La Manna, Federica Licciardi, Giuseppe Vitiello, Valeria Panzetta, Paolo Antonio Netti, Giuseppina Luciani and Daniela Marasco

International Journal of Biological Macromolecules, 2025, 312, 144175
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Constructing epigallocatechin gallate/nano-ceria coating to enhance osteogenesis of titanium implants via alleviating oxidative stress

Shuoqi Wang, Shuang Wu, Senxiong Meng, Yuchen Lin, Lei Wang, Mei Tu and Rong Zeng

J Mater Sci, 2024, 59, 16207
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Hyperbranched polymer dots enhance hair follicle regeneration via Wnt/β-catenin activation: A drug-free nanozyme-based approach to hair growth therapy

Chang-Cheng Chang, Siao-Cian Fan, Yen-Jen Wang, Wen-Ping Jiang, Yi-Hsuan Su, Jing-Chun Yang, Audry-Yun-Xuan Chan, Yu-Xuan Yang, Yu-Hsuan Lee, Ching-Chang Cheng, Ching-Hsuan Lin and Tzong-Yuan Juang

Biomedicine & Pharmacotherapy, 2025, 188, 118196
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Advances in preparation and modification strategies of CeO2 nanozymes and potential clinical applications

Zhixuan Li, Xinying Wang, Han Wu and Qingxiang Guan

Chinese Chemical Letters, 2025, 111671
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CART and Ceria nanozyme co-loaded ROS-responsive nanogel for synergistic treatment of Alzheimer's disease

Yuxuan Dai, Shenghan Gao, Zhi Zhang, Wan-Jie Du, Xinyu Bao and Yun Xu

Chemical Engineering Journal, 2025, 522, 168038
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NOS-like activity of CeO2 nanozymes contributes to diminishing the vascular plaques

Yuxiang Sun, Tianze Xu, Yike Qian, Qiaoyun Chen, Fei Xiong, Wenxian Du and Li Xu

J Nanobiotechnol, 2024, 22
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Potentiality of Nanoenzymes for Cancer Treatment and Other Diseases: Current Status and Future Challenges

Rakesh K. Sindhu, Agnieszka Najda, Prabhjot Kaur, Muddaser Shah, Harmanpreet Singh, Parneet Kaur, Simona Cavalu, Monika Jaroszuk-Sierocińska and Md. Habibur Rahman

Materials, 2021, 14, 5965
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Nanoceria: an innovative strategy for cancer treatment

Joyce L. Y. Tang, Shehzahdi S. Moonshi and Hang T. Ta

Cell. Mol. Life Sci., 2023, 80
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One stone, two birds: A Cu-S cluster as a laccase-mimicking nanozyme and sulfite activator for phenol remediation in marine environments

Wei Xu, Yifei Zhang, Xia Zhang, Xinxin Xu and Qiang Wang

Journal of Hazardous Materials, 2023, 457, 131776
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PB/CeO2 Nanoparticles Regulating Reactive Oxygen Species for the Control of Enterococcus faecalis Infection in Root Canals

Huiwen Wang, Yuting Wu, Mingrui Dai, Tingting Zhu, Daming Wu and Diya Leng

J Biomed Mater Res, 2025, 113
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Transition-Metal-Based Nanozymes: Synthesis, Mechanisms of Therapeutic Action, and Applications in Cancer Treatment

Qinrui Fu, Chuang Wei and Mengzhen Wang

ACS Nano, 2024, 18, 12049
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Porous, Oxygen Vacancy Enhanced CeO2–x Microspheres with Efficient Enzyme-Mimetic and Photothermal Properties

Cagil Zeynep Sungu Akdogan, Burcu Gokcal, Mustafa Polat, Kadriye Ozlem Hamaloglu, Cigdem Kip and Ali Tuncel

ACS Sustainable Chem. Eng., 2022, 10, 9492
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ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy

Wenjing Mo, Shujie Liu, Xiaozhi Zhao, Fayun Wei, Yuhang Li, Xinan Sheng, Wenmin Cao, Meng Ding, Wenlong Zhang, Xiaoqing Chen, Longxiyu Meng, Sheng Yao, Wenli Diao, Hui Wei and Hongqian Guo

Adv Healthcare Materials, 2023, 12
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ChatGPT Combining Machine Learning for the Prediction of Nanozyme Catalytic Types and Activities

Liping Sun, Jili Hu, Yinfeng Yang, Yongkang Wang, Zijian Wang, Yong Gao, Yiqi Nie, Can Liu and Hongxing Kan

J. Chem. Inf. Model., 2024, 64, 6736
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Signal “Off–On Model’’ for Colorimetric Sensing Proanthocyanidin B2 Achieved by the Organic Solvent-Processed Amorphous BiVO4 Nanozyme

Fu-Long Lu, Yun-Yun Wu, Shu-Jie Feng, Xiu-Shuang Yang, Xin Tian, Hao-Yu Ma, Wei Wang, Wen-Sheng Zhang, Dong-Xue Han, Dong-Dong Qin, Dong-Fang Han and Li Niu

Anal. Chem., 2025, 97, 7165
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Nanoceria-decorated Graphene Nanosheets Enhance Mechanical Properties and Bioactivity of a Degradable Polyurethane for Biomedical Applications

Sagar Nilawar, Mohankumar BS and Kaushik Chatterjee

J Polym Environ, 2023, 31, 2941
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Artificial intelligence driven platform for rapid catalytic performance assessment of nanozymes

Wenjie Xuan, Xiaofo Li, Honglei Gao, Luyao Zhang, Jili Hu, Liping Sun and Hongxing Kan

Sci Rep, 2025, 15
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Artificial Intelligence for Nanostructured Materials

Z. M. Gadzhimagomedova, D. M. Pashkov, D. Yu. Kirsanova, S. A. Soldatov, M. A. Butakova, A. V. Chernov and A. V. Soldatov

Nanotechnol Russia, 2022, 17, 1
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The engineering design of single-site nanozyme based on metal-organic layers for the detection of antioxidant substances

Z. Wu, J. Wen, J. Li, L. Chen, W. Li and K. Yang

Materials Today Chemistry, 2023, 30, 101598
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Peroxidase-like Activity of CeO2 Nanozymes: Particle Size and Chemical Environment Matter

Arina D. Filippova, Madina M. Sozarukova, Alexander E. Baranchikov, Sergey Yu. Kottsov, Kirill A. Cherednichenko and Vladimir K. Ivanov

Molecules, 2023, 28, 3811
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Nanostructured Ceria: Biomolecular Templates and (Bio)applications

Petr Rozhin, Michele Melchionna, Paolo Fornasiero and Silvia Marchesan

Nanomaterials, 2021, 11, 2259
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A nanozyme with switchable enzyme-like activity for the logic gates detection of thymol and hydrogen peroxide in honey

Jie Li, Luwei Wang, Donghui Song, Yongxin Li and Hui Huang

Talanta, 2024, 274, 125951
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Towards nanostructured red-ox active bio-interfaces: Bioinspired antibacterial hybrid melanin-CeO2 nanoparticles for radical homeostasis

Giulio Pota, Brigida Silvestri, Giuseppe Vitiello, Noemi Gallucci, Rocco Di Girolamo, Stefania Scialla, Maria Grazia Raucci, Luigi Ambrosio, Michela Di Napoli, Anna Zanfardino, Mario Varcamonti, Alessandro Pezzella and Giuseppina Luciani

Biomaterials Advances, 2023, 153, 213558
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Matrix redox interference-free nanozyme-amplified detection of Hg2+ using thiol-modified phosphatase-mimetic nanoceria

Panwang Hu, Jinjin Liu, Changkun Xia, Bangxiang Liu, Hengjia Zhu and Xiangheng Niu

Sensors and Actuators B: Chemical, 2024, 401, 135030
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Modular configurations of living biomaterials incorporating nano-based artificial mediators and synthetic biology to improve bioelectrocatalytic performance: A review

Zheng Chen, Jing Zhang, Qingyang Lyu, Honghui Wang, Xiaoliang Ji, Zhiying Yan, Fang Chen, Randy A. Dahlgren and Minghua Zhang

Science of The Total Environment, 2022, 824, 153857
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Antibacterial properties of cerium oxide nanoparticles: Recent progresses and future challenges

Heishu Zheng, Jiajing Tang, Yanhua Wei, Xi Deng, Yingjuan Zhang, Xiangyu Ma, Xudong Jiang, Zhi Ping Xu and Hongbing Liao

Particuology, 2024, 93, 264
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Self-Cascade of the Cu/Ce-MOF-808 Nanozyme for One-Step Colorimetric Sensing

Yuan Qin, Huimei Liang, Jia Wu, Zheyang Chi, Shulin Zhao and Fanggui Ye

Anal. Chem., 2025, 97, 8468
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Nanozymes for biomedical applications in orthopaedics

Anqi Lin, Shujie Liu and Hui Wei

Particuology, 2023, 76, 32
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Nanozymes with Multiple Activities: Prospects in Analytical Sensing

Xiangheng Niu, Bangxiang Liu, Panwang Hu, Hengjia Zhu and Mengzhu Wang

Biosensors, 2022, 12, 251
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In Situ Fabrication of Nanoceria with Oxidase-like Activity at Neutral pH: Mechanism and Boosted Bio-Nanozyme Cascades

Jinyi Zhang, Jie Wang, Jing Liao, Yao Lin, Chengbin Zheng and Juewen Liu

ACS Appl. Mater. Interfaces, 2021, 13, 50236
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Vanadium Carbide Nanosheets with Broad-Spectrum Antioxidant Activity for Pulmonary Fibrosis Therapy

Quan Liu, Yaping Ren, Huimin Jia, Hao Yuan, Yuping Tong, Sumasri Kotha, Xiaobo Mao, Yongwei Huang, Chunying Chen, Zhi Zheng, Liming Wang and Weiwei He

ACS Nano, 2023, 17, 22527
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Stable detection of diazinon residues in vegetables by an electrochemiluminescent aptasensor based on the in-situ production of H2O2 from dual-catalytic glucose

Jingcheng Huang, Mei Zhang, Xue Huang, He Li, Jie Han, Shancang Zhao, Mohamed Bedair Mohamed Ahmed, Xia Sun and Yemin Guo

Talanta, 2024, 277, 126443
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Multi-enzyme activity nanozymes for biosensing and disease treatment

Li Su, Sainan Qin, Zhongjian Xie, Liang Wang, Karim Khan, Ayesha Khan Tareen, Defa Li and Han Zhang

Coordination Chemistry Reviews, 2022, 473, 214784
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A novel strategy for identification of pesticides in different categories by concentration-independent model based on a nanozyme with multienzyme-like activities

Donghui Song, Lulu Lei, Tian Tian, Xiaoyu Yang, Luwei Wang, Yongxin Li and Hui Huang

Biosensors and Bioelectronics, 2023, 237, 115458
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Laccase and peroxidase mimetic CuxO-ZnO microstructures for optical biosensing applications

Surbhi Singh, Anju Jangir, Siddarth Jain, Nisha Verma and Bhagwati Sharma

Journal of Materials Research, 2023, 38, 3638
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Low-Temperature Inactivation of Enzyme-like Activity of Nanocrystalline CeO2 Sols

A. D. Filippova, M. M. Sozarukova, A. E. Baranchikov, A. A. Egorova, K. A. Cherednichenko and V. K. Ivanov

Russ. J. Inorg. Chem., 2022, 67, 1948
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Multifunctional Nanoplatform for Mild Microwave-Enhanced Thermal, Antioxidative, and Chemotherapeutic Treatment of Rheumatoid Arthritis

Lianying Zhang, Wei Meng, Xiaotong Chen, Libo Wu, Mingwa Chen, Zhaoxi Zhou, Yongjian Chen, Lixia Yuan, Ming Chen, Jinxiang Chen and Pixian Shui

ACS Appl. Mater. Interfaces, 2023, 15, 10341
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Gold-Cerium bimetallic Star-Shaped nanoplatform for synergistic tumor therapy with nanozyme Catalytic/Photothermal/Chemotherapy

Chao Li, Zichao Guo, Wenqing Jia, Yan Kang, Meiling Zeng, Tingting Gu, Chaohui Zhou, Ren Zhao, Xi Cheng and Nengqin Jia

Journal of Colloid and Interface Science, 2025, 685, 753
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Impact of bridging the gap between Artificial Intelligence and nanomedicine in healthcare

Divyam Mishra, Bhavishya Chaturvedi, Vishal Soni, Dhairya Valecha, Megha Goel and Jamilur R. Ansari

Next Nanotechnology, 2025, 8, 100203
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hCeO2@ Cu5.4O nanoparticle alleviates inflammatory responses by regulating the CTSB–NLRP3 signaling pathway

Ying Li, Xiaomin Xia, Zhaojun Niu, Ke Wang, Jie Liu and Xue Li

Front. Immunol., 2024, 15
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