Classification of chemically modified red blood cells in microflow using machine learning video analysis

R. K. Rajaram Baskaran, A. Link, B. Porr and T. Franke

Soft Matter, 2024, 20, 952
DOI: 10.1039/D3SM01337E

On-chip characterization of cell mechanics assisted by external physical fields and artificial intelligence

Jingjin Ge, Chenhao Bai, Zhuo Chen, Toshio Fukuda, Tatsuo Arai and Xiaoming Liu

Lab Chip, 2026, 26, 1528
DOI: 10.1039/D5LC00855G

Impact of sequential bifurcations on the cell-free layer of healthy and rigid red blood cells

Yazdan Rashidi, Christian Wagner and Steffen M. Recktenwald

Lab Chip, 2025, 25, 5055
DOI: 10.1039/D4LC00865K

Evaluating anti-sickling therapies for sickle cell disease: a microfluidic assay for red blood cell-mediated microvascular occlusion under hypoxia

Zoe Sekyonda, Yuxuan Du, Solomon Oshabaheebwa, Payam Fadaei, Yusang B. Ley, Calvin Abonga, Michael A. Suster, Pedram Mohseni and Umut A. Gurkan

Lab Chip, 2025, 25, 6256
DOI: 10.1039/D5LC00264H

Morphology, repulsion, and ordering of red blood cells in viscoelastic flows under confinement

Steffen M. Recktenwald, Yazdan Rashidi, Ian Graham, Paulo E. Arratia, Francesco Del Giudice and Christian Wagner

Soft Matter, 2024, 20, 4950
DOI: 10.1039/D4SM00446A

High-throughput biomimetic cycling of red blood cells: elucidating the morpho-mechanical determinants of fatigue and clearance

Yahui Du, Wenjiao Wu, Yuexiu Chen, Lihang Zhu, Shuhao Ma, Fengjiang Zhang and Xuejin Li

Lab Chip, 2026, 26, 551
DOI: 10.1039/D5LC01022E

Structural and mechanical properties of the red blood cell’s cytoplasmic membrane seen through the lens of biophysics

Sebastian Himbert and Maikel C. Rheinstädter

Front. Physiol., 2022, 13
DOI: 10.3389/fphys.2022.953257

Big Data in Transfusion Medicine and Artificial Intelligence Analysis for Red Blood Cell Quality Control

Marcelle G.M. Lopes, Steffen M. Recktenwald, Greta Simionato, Hermann Eichler, Christian Wagner, Stephan Quint and Lars Kaestner

Transfus Med Hemother, 2023, 50, 163
DOI: 10.1159/000530458

Evaluating the viscoelastic properties and folding dynamics of red blood cells maintained at 4 °C using optical tweezers

Theodoros Giannakis, Sotirios P. Fortis, Sergey V. Starinskiy, Anastasios G. Kriebardis and Maria Kandyla

Appl. Phys. B, 2026, 132
DOI: 10.1007/s00340-026-08646-9

Extensional-Flow Impedance Cytometer for Contactless and Optics-Free Erythrocyte Deformability Analysis

Riccardo Reale, Adele De Ninno, Tiziana Nepi, Paolo Bisegna and Federica Caselli

IEEE Trans. Biomed. Eng., 2023, 70, 565
DOI: 10.1109/TBME.2022.3197214

Investigation of Anemia and Pure Blood through Surface Plasmon Polaritons using COMSOL and Statistical Analysis

Aqsa Ashraf, Muhammad Asad Javed, Abdullah Almohammedi, Tahir Iqbal and Sumera Afsheen

BioNanoSci., 2025, 15
DOI: 10.1007/s12668-025-01851-4

Effect of Cell Age and Membrane Rigidity on Red Blood Cell Shape in Capillary Flow

Mohammed Nouaman, Alexis Darras, Thomas John, Greta Simionato, Minke A. E. Rab, Richard van Wijk, Matthias W. Laschke, Lars Kaestner, Christian Wagner and Steffen M. Recktenwald

Cells, 2023, 12, 1529
DOI: 10.3390/cells12111529

Quantifying the deformability of malaria-infected red blood cells using deep learning trained on synthetic cells

Daniel T. Rademaker, Joshua J. Koopmans, Gwendolyn M.S.M. Thyen, Aigars Piruska, Wilhelm T.S. Huck, Gert Vriend, Peter A.C. ‘t Hoen, Taco W.A. Kooij, Martijn A. Huynen and Nicholas I. Proellochs

iScience, 2023, 26, 108542
DOI: 10.1016/j.isci.2023.108542

Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies

Dmitry S. Prudinnik, Aigul Kussanova, Ivan A. Vorobjev, Alexander Tikhonov, Fazly I. Ataullakhanov and Natasha S. Barteneva

Aging and disease, 2024, 0
DOI: 10.14336/AD.2024.0526

Hypothesized molecular mechanism of formation of membrano-cystic lesions

Toshitsugu Nakamura

Medical Hypotheses, 2025, 195, 111561
DOI: 10.1016/j.mehy.2024.111561

Actin instability alters red blood cell mechanics and Piezo1 channel activity

Nicoletta Braidotti, Davide Rizzo, Catalin D. Ciubotaru, Giuseppina Sacco, Annalisa Bernareggi and Dan Cojoc

Biomech Model Mechanobiol, 2025, 24, 507
DOI: 10.1007/s10237-024-01921-8

Blood Mechanical Intelligence: From Force Sensing to Precision Mechanomedicine

Shichun Wang, Ting Pan, Qi Liu, Zedong Li, Ting Wen, Bo Cheng, Feng Xu and Chunyan Yao

Research, 2026, 9
DOI: 10.34133/research.1157

PM2.5 induces a senescent state in mouse AT2 cells

Peiyong Cheng, Yongqi Chen, Jianhai Wang, Ziyu Han, De Hao, Yu Li, Feifei Feng, Xuexin Duan and Huaiyong Chen

Environmental Pollution, 2024, 347, 123686
DOI: 10.1016/j.envpol.2024.123686

Label-Free and Noninvasive Single-Cell Characterization for the Viscoelastic Properties of Cryopreserved Human Red Blood Cells Using a Dielectrophoresis-On-a-Chip Approach

Qianqian Hu, Zirui Wang, Lingxiao Shen and Gang Zhao

Anal. Chem., 2022, 94, 10245
DOI: 10.1021/acs.analchem.2c01858

Confinement effect on the microcapillary flow and shape of red blood cells

Mohammed Nouaman, Alexis Darras, Christian Wagner and Steffen M. Recktenwald

Biomicrofluidics, 2024, 18
DOI: 10.1063/5.0197208

A novel red blood cell deformability biomarker is associated with hemolysis and vaso-occlusive crises in sickle cell disease

Maxime Sahun, Emmanuelle Bernit, Scott Atwell, Alexander Hornung, Anne M. Charrier, Imane Agouti, Nathalie Bonello-Palot, Mathieu Cerino, Emmanuèle Helfer, Catherine Badens and Annie Viallat

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-00152-w

Energy spectrum analysis on a red blood cell model

Tetsuya Yamamoto and Hiroshi Watanabe

The Journal of Chemical Physics, 2023, 159
DOI: 10.1063/5.0169467

Cells in the polyaneuploid cancer cell (PACC) state have increased metastatic potential

Mikaela M. Mallin, Nicholas Kim, Mohammad Ikbal Choudhury, Se Jong Lee, Steven S. An, Sean X. Sun, Konstantinos Konstantopoulos, Kenneth J. Pienta and Sarah R. Amend

Clin Exp Metastasis, 2023, 40, 321
DOI: 10.1007/s10585-023-10216-8

Recent advances in microscale techniques for red blood cells manipulation

Huihui Xu, Huijing Zhang, Tiechuan Li and Xuexin Duan

Biomicrofluidics, 2025, 19
DOI: 10.1063/5.0267049

Diffusiophoretic Trapping and Assembly of Nanoparticles Enhanced by Multilayer MXene Nanosheet

Fengya Lu, Jiankang Wang, Peipei Wei, Xinyu Fan, Jifu Lyu, Hao Wu, Changxu Li, Haoqi Luo, Zhensheng Zhong, Yu‐Xuan Ren and Jinhua Zhou

Advanced Optical Materials, 2025, 13
DOI: 10.1002/adom.202501240

In vivo optical trapping of erythrocytes in mouse liver imaged with oblique back-illumination microscopy

Meng Shao, Rui Liu, Changxu Li, Zhe Chai, Zhensheng Zhong, Fengya Lu, Xunbin Wei, Jinhua Zhou and Min-Cheng Zhong

Applied Physics Letters, 2023, 123
DOI: 10.1063/5.0153442

Comparison of stress-induced hemolysis in neonatal intravenous catheters: Theoretical and experimental analysis of shear stress, exposure time, and index of hemolysis

Gordon Y Chang, Cynthia A Cox, Ellen A Kane, Giovanna Palermo Tye, Paul Fawcett and Thomas H Shaffer

Journal of Neonatal-Perinatal Medicine, 2025, 18, 255
DOI: 10.1177/19345798251326071

Pathophysiological Associations and Measurement Techniques of Red Blood Cell Deformability

Minhui Liang, Dawei Ming, Jianwei Zhong, Choo Sheriel Shannon, William Rojas-Carabali, Kajal Agrawal, Ye Ai and Rupesh Agrawal

Biosensors, 2025, 15, 566
DOI: 10.3390/bios15090566

Evaluation of the Pharmaceutical Activities of Chuanxiong, a Key Medicinal Material in Traditional Chinese Medicine

Shiwei Huang, Jiamei Chen, Xiaohua Liu, Chunxin Xing, Lu Zhao, Kelvin Chan and Guanghua Lu

Pharmaceuticals, 2024, 17, 1157
DOI: 10.3390/ph17091157

Brain endothelial cells as phagocytes: mechanisms and implications

Rudy T. Chang, Mark J. Fisher and Rachita K. Sumbria

Fluids Barriers CNS, 2025, 22
DOI: 10.1186/s12987-025-00637-w

Low-cost optical sensors in electrified lab-on-a-disc platforms: liquid-phase boundary detection and automated diagnostics

Vahid Kordzadeh-Kermani, Maryam Vahid, Seyed Nezameddin Ashrafizadeh, Sergio O. Martinez-Chapa, Marc J. Madou and Masoud Madadelahi

Microsyst Nanoeng, 2025, 11
DOI: 10.1038/s41378-025-00896-5

RBC deformability and clinical relevance in transfusion recipients

Mahsa Yazdanbakhsh, Celina Phan, Pratham Patel, Ethan Simpson, Kaitlyn Wingnean and Jason P. Acker

Transfusion and Apheresis Science, 2025, 64, 104278
DOI: 10.1016/j.transci.2025.104278

Measuring Asymmetric Ionic Current Waveform Through Micropores for Detecting Reduced Red Blood Cell Deformability Due to Plasmodium falciparum Infection

Kazumichi Yokota, Ken Hirano, Kazuaki Kajimoto and Muneaki Hashimoto

Sensors, 2025, 25, 4722
DOI: 10.3390/s25154722

Intelligent image-based deformability assessment of red blood cells via dynamic shape classification

Minhui Liang, Jianwei Zhong, Choo Sheriel Shannon, Rupesh Agrawal and Ye Ai

Sensors and Actuators B: Chemical, 2024, 401, 135056
DOI: 10.1016/j.snb.2023.135056

Direct insights into synthesis, protein integrity, and blood microrheology of albumin microbubbles

Tatiana M. Estifeeva, Denis A. Borozdenko, Arina V. Papugaeva, Galina L. Kalinichenko, Irina P. Vlasova, Leonid I. Gudzerov, Timur Aliev, Nikita A. Krotkov, Alexey V. Boltenko, Anna O. Orlova, Anna M. Nechaeva, Yaroslav O. Mezhuev, Irina M. Le-Deygen, Dmitry A. Bunin, Vladislav S. Petrovskii, Gennady B. Khomutov, Matvei K. Maksimov, Andrei E. Lugovtsov, Alexander V. Priezzhev, Igor I. Potemkin, Dmitry A. Gorin, Yulia G. Gorbunova, Ekaterina V. Skorb, Sviatlana A. Ulasevich, Roman A. Barmin and Polina G. Rudakovskaya

Acta Biomaterialia, 2025, 206, 267
DOI: 10.1016/j.actbio.2025.09.026

A miniaturized wash-free microfluidic assay for electrical impedance-based assessment of red blood cell-mediated microvascular occlusion

Solomon Oshabaheebwa, Christopher A. Delianides, Akshay A. Patwardhan, Erica N. Evans, Zoe Sekyonda, Allison Bode, Faith M. Apio, Cissy K. Mutuluuza, Vivien A. Sheehan, Michael A. Suster, Umut A. Gurkan and Pedram Mohseni

Biosensors and Bioelectronics, 2024, 258, 116352
DOI: 10.1016/j.bios.2024.116352

Dose-dependent effects of diamide and glutaraldehyde on red blood cell deformability, viscosity, and morphology

Tatiana Turcitu, Kyle Champagne, Andy Vinh Le and Marianne Fenech

Microvascular Research, 2026, 165, 104917
DOI: 10.1016/j.mvr.2026.104917

Direct observation of deformation of individual red blood cells in oscillatory fluid flow produced using a generator of precise sinusoidal shear flow

Kriengsak Masnok, Masataka Inoue and Nobuo Watanabe

AIP Advances, 2022, 12
DOI: 10.1063/5.0113873

Ultrasensitive microfluidic detection of red blood cell deformability: Age-related decline in deformability

Jihee You, Chae-A Park, Ae-Kyeong Kim, Hye Ran Jeon, Dong-Ik Kim and Sehyun Shin

Physics of Fluids, 2025, 37
DOI: 10.1063/5.0281533

High Performance Antibacterial Structure‐Tuned Hemofiltration Membrane for Facile Permeability of Blood Plasma During Plasmapheresis

Rahim Dehghan, Jalal Barzin and Zahra Kordkatooli

Polymers for Advanced Techs, 2024, 35
DOI: 10.1002/pat.6644

Efficient characterization of red blood cell rheological properties using a multichannel microfluidic chip and optical tweezers

Ying Liu, Hongtao Rao, Hongliang Zhang, Meng Wang, Yinglian Wu, Ying Wu, Caiqin Han, Changchun Yan, Le Zhang, Wei Chen and JingJing Wang

Materials Today Advances, 2024, 24, 100545
DOI: 10.1016/j.mtadv.2024.100545

RBC aggregation, deformation and adhesion to endothelium: Role of nitric oxide derived from L-Arginine and sodium nitroprusside

M. K. Maksimov, P. B. Ermolinskiy, O. N. Scheglovitova, N. N. Sklyankina, A. V. Muravyov, A. E. Lugovtsov and A. V. Priezzhev

J. Innov. Opt. Health Sci., 2024, 17
DOI: 10.1142/S1793545824400017

Fluid Mechanics of Blood Cells and Vesicles Squeezing Through Narrow Constrictions

Zhangli Peng, Annie Viallat and Yuan-Nan Young

Annual Review of Fluid Mechanics, 2026, 58, 331
DOI: 10.1146/annurev-fluid-112723-052727

Computational Simulation of the Hemodynamics in an Anatomic Carotid Artery Model: A Biphasic Blood Model

Mariana Ferreira, Violeta Carvalho, Diana Pinho, Rui Lima, Senhorinha Teixeira and Armando A. Soares

Journal of Engineering and Science in Medical Diagnostics and Therapy, 2025, 8
DOI: 10.1115/1.4067516

Iron Overload-Related Oxidative Stress Leads to Hyperphosphorylation and Altered Anion Exchanger 1 (Band 3) Function in Erythrocytes from Subjects with β-Thalassemia Minor

Sara Spinelli, Elisabetta Straface, Lucrezia Gambardella, Daniele Caruso, Silvia Dossena, Angela Marino, Rossana Morabito and Alessia Remigante

IJMS, 2025, 26, 1593
DOI: 10.3390/ijms26041593

A Microfluidic Device for Detecting the Deformability of Red Blood Cells

Wenyan Liu, Liqiang Xie, Jiangcun Yang, Xiaobo Gong, Dan Sun and Ce Zhang

Biosensors, 2025, 15, 758
DOI: 10.3390/bios15110758

Tools and metrics for the assessment of post‐storage performance of red blood cells: no one is left over

Marianna H. Antonelou

Transfusion, 2023, 63, 1
DOI: 10.1111/trf.17228

Imaging transzonal projections in the cumulus–oocyte complexes: challenges and solutions

Mathilde Marchais, Alexandre Bastien, Elolo Karen Nenonene, Edouard W Khandjian, Isabelle Gilbert and Claude Robert

Biology of Reproduction, 2025, 113, 1414
DOI: 10.1093/biolre/ioaf204

Clinical Outcomes of CRISPR-Cas9 Mediated Gene Editing in Patients with Sickle Cell Disease: A Biotechnology-Based Therapeutic Approach

Hashim Raza, Mahwish Riaz, Umm E Habiba and Zahid Mehboob

IRABCS, 2025, 3, 15
DOI: 10.62497/IRABCS.126

Biophysical profiling of red blood cells from thin-film blood smears using deep learning

Erik S. Lamoureux, You Cheng, Emel Islamzada, Kerryn Matthews, Simon P. Duffy and Hongshen Ma

Heliyon, 2024, 10, e35276
DOI: 10.1016/j.heliyon.2024.e35276

Machine learning microfluidic based platform: Integration of Lab-on-Chip devices and data analysis algorithms for red blood cell plasticity evaluation in Pyruvate Kinase Disease monitoring

A. Mencattini, V. Rizzuto, G. Antonelli, D. Di Giuseppe, M. D’Orazio, J. Filippi, M.C. Comes, P. Casti, J.L. Vives Corrons, M. Garcia-Bravo, J.C. Segovia, Maria del Mar Mañú-Pereira, M.J. Lopez-Martinez, J. Samitier and E. Martinelli

Sensors and Actuators A: Physical, 2023, 351, 114187
DOI: 10.1016/j.sna.2023.114187