Novel scandium-MOF nanocrystals as peroxidase-mimicking nanozymes for highly sensitive colorimetric detection of ascorbic acid in human serum

Yiqian Su, Hongjiao Wu, Jiaqi Chen, Huiqin Li, Pengcheng Lin, Wei Xiao and Donglin Cao

CrystEngComm, 2023, 25, 3472
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Advances in nanozymes with peroxidase-like activity for biosensing and disease therapy applications

Xiaohua Yuan, Xun He, Jiwen Fan, Yunze Tai, Yongchao Yao, Yao Luo, Jie Chen, Han Luo, Xingli Zhou, Fengming Luo, Qian Niu, Wenchuang (Walter) Hu, Xuping Sun and Binwu Ying

J. Mater. Chem. B, 2025, 13, 1599
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MXene-based nanomaterials with enzyme-like properties for biomedical applications

Rong Yang, Shiqi Wen, Shuangfei Cai, Wei Zhang, Ting Wu and Youlin Xiong

Nanoscale Horiz., 2023, 8, 1333
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Smartphone-based colorimetric detection systems for glucose monitoring in the diagnosis and management of diabetes

Özlem Kap, Volkan Kılıç, John G. Hardy and Nesrin Horzum

Analyst, 2021, 146, 2784
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Recent advances in MXene nanozymes: synthesis, surface modifications, catalytic properties, and their emerging roles in biosensing and therapeutic applications

Hatem A. Al-Aoh, Chellasamy Panneerselvam, Asim. M. Alghamdi, Abdulrahman Alasmari and Zuhair M. Mohammedsaleh

Analyst, 2026, 151, 991
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Stimuli-responsive one-dimensional photonic crystals: design, fabrication and sensing

Marie Däntl, Alberto Jiménez-Solano and Bettina V. Lotsch

Mater. Adv., 2022, 3, 7406
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Emerging 2D MXene-conjugated nanoarchitectures for nanozymes: current advances and future frontiers in biochemical sensing technologies

Ramar Rajamanikandan, Kandasamy Sasikumar and Heongkyu Ju

Environ. Sci.: Nano, 2025, 12, 4796
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DNA controllable peroxidase-like activity of Ti3C2 nanosheets for colorimetric detection of microcystin-LR

Jingfang Guo, Guodong Wang, Jing Zou and Zhen Lei

Anal Bioanal Chem, 2023, 415, 3559
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2D Ti3C2Tx MXene nanozymes based electrochemical MicroRNA biosensor and application to early diagnosis of sepsis-associated acute kidney injury

Xiangyu Deng, Xia Zheng, Anyi Chen, Yuqing Li, Siling Chen, Jiangling Wu, Jianjiang Xue, Rongjun Yu, Min Zhao and Jingfu Qiu

Microchim Acta, 2025, 192
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MXenes and their applications in electrochemical sensors for pharmaceutical analysis

Amir M. Ashrafi, Milan Sýs, Tong Liu, Michaela Bártová and Jiří Homola

Electrochimica Acta, 2026, 558, 148522
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Fast colorimetric sensing of H2O2 and glutathione based on Pt deposited on NiCo layered double hydroxide with double peroxidase-/oxidase-like activity

Xiaoyan Cao, Hui Yang, Qiulian Wei, Yanting Yang, Mei Liu, Qingyun Liu and Xianxi Zhang

Inorganic Chemistry Communications, 2021, 123, 108331
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Tunable Structured Metal Oxides for Biocatalytic Therapeutics

Minjia Yuan, Qian Li, Yang Gao, Chao He, Mohsen Adli, Changzhu Wu, Hongju Zhou, Xianglin Luo, Lang Ma and Chong Cheng

Adv Funct Materials, 2023, 33
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Ti3C2Tx MXene as Electrocatalyst for Designing Robust Glucose Biosensors

Rajesh Kumar and Lakhveer Singh

Adv Materials Technologies, 2022, 7
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Nanozymes for nanohealthcare

Yihong Zhang, Gen Wei, Wanling Liu, Tong Li, Yuting Wang, Min Zhou, Yufeng Liu, Xiaoyu Wang and Hui Wei

Nat Rev Methods Primers, 2024, 4
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Enzyme-like nanomaterials-integrated microfluidic technology for bioanalysis

Fengyang Zhao, Wenli Wu, Mei Zhao, Shichao Ding, Yuehe Lin, Qiongzheng Hu and Li Yu

TrAC Trends in Analytical Chemistry, 2023, 158, 116833
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Nanozymes: Activity origin, catalytic mechanism, and biological application

Wenping Yang, Xin Yang, Longjiao Zhu, Huashuo Chu, Xiangyang Li and Wentao Xu

Coordination Chemistry Reviews, 2021, 448, 214170
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Selective oxidation of p-phenylenediamine for blood glucose detection enabled by Se-vacancy-rich TiSe2-x@Au nanozyme

Caixia Sun, Xue Zhang, Hao Huang, Ya Liu, Xianwei Mo, Yufei Feng, Jiahong Wang, Wenhua Zhou, Paul K. Chu, Xue-Feng Yu and Wenxin Liu

Biosensors and Bioelectronics, 2023, 241, 115665
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Integrating of analytical techniques with enzyme-mimicking nanomaterials for the fabrication of microfluidic systems for biomedical analysis

Sherzod Shukhratovich Abdullaev, Raed H Althomali, Ahmad Raza Khan, Hijran Sanaan Jabbar, Munther abosoda, Ali ihsan, Saurabh Aggarwal, Yasser Fakri Mustafa, Ibrahim Hammoud Khlewee and Abeer mhussan jabbar

Talanta, 2024, 273, 125896
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Cu nanoclusters decorated Ti3C2 nanosheets composite with tetraenzyme mimic activities and the application for smartphone-assisted detection of hypoxanthine

Qinqin Yang, Xipeng Cui, Ying Qin, Tiantian Lei, Yu He and Gongwu Song

Analytica Chimica Acta, 2022, 1232, 340494
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Advances in bimetallic materials and bimetallic oxide nanozymes: Synthesis, classification, catalytic mechanism and application in analytical chemistry

Yun-Yun Wu, Xin Tian, Yuan Jiang, Hao-Yu Ma, Wei Wang, Wen-Sheng Zhang, Jovan San Martin, Yong Yan, Dong-Dong Qin, Dong-Xue Han and Li Niu

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A Titanium Nitride Nanozyme for pH‐Responsive and Irradiation‐Enhanced Cascade‐Catalytic Tumor Therapy

Jiaming Liu, Aizhu Wang, Shihui Liu, Ruiqi Yang, Longwei Wang, Fene Gao, Huige Zhou, Xin Yu, Jing Liu and Chunying Chen

Angewandte Chemie, 2021, 133, 25532
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Tunable Structured 2D Nanobiocatalysts: Synthesis, Catalytic Properties and New Horizons in Biomedical Applications

Qiqi Cui, Yang Gao, Qinlong Wen, Ting Wang, Xiancheng Ren, Liang Cheng, Mingru Bai and Chong Cheng

Small, 2024, 20
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Co(OH)2/MXene-Ti3C2 nanocomposites with triple-enzyme mimic activities as hydrogel sensing platform for on-site detection of hypoxanthine

Qinqin Yang, Ying Qin, Tiantian Lei, Yaping Zhong, Xipeng Cui, Yu He and Gongwu Song

Microchim Acta, 2022, 189
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MXene‐Based Nanozymes: Current Challenges and Future Prospects

Eleonora Pargoletti and Yury Gogotsi

ChemCatChem, 2025, 17
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Facile Synthesis of MXene-Ti3C2/Co Nanosheet Hydrogel Sensor with the Assistance of a Smartphone for On-Site Monitoring of Glucose in Beverages

Ziling Li, Tiantian Lei, Ting Pei, Keyan Chen, Zhidong Zhao, Manman Wang and Yu He

Molecules, 2023, 28, 5075
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Two-dimensional derivatives obtained by oxidation of MXene for simulating the oxidative properties of natural enzymes

Qiang Peng, Nian Jiang, Ling Qian and Wanqing Yue

2D Mater., 2023, 10, 045013
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Smartphone-Enabled Fluorescence and Colorimetric Platform for the On-Site Detection of Hg2+ and Cl− Based on the Au/Cu/Ti3C2 Nanosheets

Keyan Chen, Shiqi Fu, Chenyu Jin, Fan Guo, Yu He, Qi Ren and Xuesheng Wang

Molecules, 2023, 28, 5355
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Nitrogen and sulfur co-doping strategy to trigger the peroxidase-like and electrochemical activity of Ti3C2 nanosheets for sensitive uric acid detection

Da Chen, Shuaibin Shao, Wei Zhang, Jingbo Zhao and Meiling Lian

Analytica Chimica Acta, 2022, 1197, 339520
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Recent Advances in the Immunoassays Based on Nanozymes

Lu Zhou, Yifan Liu, Yang Lu, Peirong Zhou, Lianqin Lu, Han Lv and Xin Hai

Biosensors, 2022, 12, 1119
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Rapid and ultrasensitive activity detection of β-amylase based on cross-linked metal-organic framework nanozyme

Wanqiu Huang, Mengdi Hao, Liangqiang Chen, Hao Shen, Shaoning Yu, Ying Han and Fan Yang

International Journal of Biological Macromolecules, 2025, 310, 143150
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Colorimetric and photothermal dual-mode immunosensor based on Ti3C2Tx/AuNPs nanocomposite with enhanced peroxidase-like activity for ultrasensitive detection of zearalenone in cereals

Na Huang, Wei Sheng, Zixin Jin, Dongmei Bai, Meiyi Sun, Lishuai Ren, Shuo Wang, Ziwuzhen Wang, Xinshuang Tang and Tingting Ya

Microchim Acta, 2023, 190
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Nanozymes in Oral Medicine: From Catalytic Design to Advanced Dental Therapies

Zheng Li, Kai Mao, Muxin Yue, Yunsong Liu and Kelong Fan

Small, 2025, 21
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Potential Biosafety of Mxenes: Stability, Biodegradability, Toxicity and Biocompatibility

Tetiana R. Dmytriv and Volodymyr I. Lushchak

The Chemical Record, 2024, 24
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Two-dimensional nanozyme nanoarchitectonics customized electrochemical bio diagnostics and lab-on-chip devices for biomarker detection

Thenmozhi Rajarathinam, Sivaguru Jayaraman, Chang-Seok Kim, Jang-Hee Yoon and Seung-Cheol Chang

Advances in Colloid and Interface Science, 2025, 341, 103474
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Construction of a dual-signal readout platform for effective glutathione S-transferase sensing based on polyethyleneimine-capped silver nanoclusters and cobalt-manganese oxide nanosheets with oxidase-mimicking activity

Zejiao Huo, Yuntai Lv, Nan Wang, Chenyu Zhou and Xingguang Su

Microchim Acta, 2024, 191
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A Titanium Nitride Nanozyme for pH‐Responsive and Irradiation‐Enhanced Cascade‐Catalytic Tumor Therapy

Jiaming Liu, Aizhu Wang, Shihui Liu, Ruiqi Yang, Longwei Wang, Fene Gao, Huige Zhou, Xin Yu, Jing Liu and Chunying Chen

Angew Chem Int Ed, 2021, 60, 25328
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A smartphone-assisted ultrasensitive colorimetric aptasensor based on DNA-encoded porous MXene nanozyme for visual detection of okadaic acid

Jingtian Chi, Peng Ju, Fan Bi, Siyu Wen, Zhenbo Xiang, Juna Chen and Meng Qiu

Food Chemistry, 2025, 464, 141776
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Fluorine-free synthesis of Ti3C2 MQDs for smartphone-based fluorescent and colorimetric determination of acetylcholinesterase and organophosphorus pesticides

Ting Pei, Yu He, Yaping Wang and Gongwu Song

Microchim Acta, 2022, 189
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Copper Nanoparticle/N-Doped Ti3C2Tx MXene Hybrids with Enhanced Peroxidase-like Activity for Colorimetric Glucose Sensing

Juan Huang, Hongfei Gu, Xiaowei Feng, Guo Wang and Zhengbo Chen

ACS Appl. Nano Mater., 2022, 5, 15531
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CeO2/Co3O4@N-doped hollow carbon microspheres with improved peroxidase-like activity for the determination of quercetin

Xiaoyan Cao, Shuang Zhao, Xiangwei Liu, Xixi Zhu, Yan Gao and Qingyun Liu

Anal Bioanal Chem, 2022, 414, 4767
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A review on recent advances in hydrogen peroxide electrochemical sensors for applications in cell detection

Yan Yu, Meng Pan, Jinrong Peng, Danrong Hu, Ying Hao and Zhiyong Qian

Chinese Chemical Letters, 2022, 33, 4133
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Spatiotemporal Immunomodulation of Macrophages via NLRP3/IL‐1β Pathway by Core‐Shell Microneedles to Promote Healing of Biofilm‐Infected Diabetic Ulcers

Yushan Yang, Nana Chen, Jian Fan, Limin Fan, Yanni Cai, Liangyi Xue, Shiyu Chen, Zichen Yang, Lulu An, Jianwei Cheng, Tianbin Ren and Yongyong Li

Small, 2025, 21
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An enzyme free self-cascade catalytic system with Au deposited bimetallic organic framework as a dual active nanozyme for glucose detection with a smartphone readout platform

Zhao Mu, Jianshuai Mu, Min Zhao and Yan Wang

Sensors and Actuators B: Chemical, 2023, 394, 134422
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Asymmetrically coordinated single-atom iron nanozymes with Fe-N1C2 structure: A peroxidase mimetic for melatonin detection

Lihong Lin, Heng Li, Hongfei Gu, Zhiyi Sun, Juan Huang, Zhenni Qian, Hang Li, Juzhe Liu, Hongyan Xi, Pengfei Wu, Qingqing Liu, Shuhu Liu, Lirong Zheng, Zhuo Chen, Zhengbo Chen and Juanjuan Qi

Nano Res., 2023, 16, 4751
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Dual Mechanism Enhanced Peroxidase-like Activity of Iron–Nickel Bimetal–Organic Framework Nanozyme and Its Application for Biosensing

Zhao Mu, Shu Wu, Jingjing Guo, Min Zhao and Yan Wang

ACS Sustainable Chem. Eng., 2022, 10, 2984
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A sensitive fluorescence detection strategy for H2O2 and glucose by using aminated Fe–Ni bimetallic MOF as fluorescent nanozyme

Zhao Mu, Jingjing Guo, Mengyuan Li, Shu Wu, Xiao Zhang and Yan Wang

Microchim Acta, 2023, 190
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Mechanism and Application of Surface-Charged Ferrite Nanozyme-Based Biosensor toward Colorimetric Detection of l-Cysteine

Hongjiao Wu, Jun Liu, Zhuoyu Chen, Pengcheng Lin, Wentao Ou, Zian Wang, Wei Xiao, Ying Chen and Donglin Cao

Langmuir, 2022, 38, 8266
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