Electrochemical-induced solvent-tuned selective C(sp3)–H bond activation towards the synthesis of C3-functionalized chromone derivatives

Ying Gao, Mingxu Wang, Jingxian Sun, Xiao-Jing Zhao and Yonghui He

Chem. Commun., 2024, 60, 5050
DOI: 10.1039/D4CC00919C

Rapid screening of unprecedented sesquiterpenes with distinctive ring skeletons from Daphne aurantiaca employing an integrated strategy

Shu-Hui Dong, Jin-Ling Han, Xin-Yu Chang, Mei-Ya Lian, Xin Zhang, Xiao-Ling Liu, Ming Bai, Xiao-Xiao Huang and Shao-Jiang Song

Org. Chem. Front., 2023, 10, 4740
DOI: 10.1039/D3QO00902E

Spiroaquilarenes A–E: unprecedented anti-inflammatory sesquiterpene polymers from agarwood of Aquilaria sinensis

Xiao-Ling Huang, Yong-Ming Yan, Dai-Wei Wang and Yong-Xian Cheng

Org. Chem. Front., 2022, 9, 2070
DOI: 10.1039/D2QO00066K

In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease 

Phaniendra Alugoju, Vishwambar Vishnu Bhandare, Vishal S. Patil, Krishna Swamy V. K. D, Prem Kumar Borugadda and Tewin Tencomnao

F1000Res, 2023, 12, 230
DOI: 10.12688/f1000research.130618.1

Five new sesquiterpenoids from agarwood of Aquilaria sinensis

Hong Zhou, Xu-Yang Li, Hong-Bin Fang, He-Zhong Jiang and Yong-Xian Cheng

Beilstein J. Org. Chem., 2023, 19, 998
DOI: 10.3762/bjoc.19.75

Aquilaria Species (Thymelaeaceae) Distribution, Volatile and Non-Volatile Phytochemicals, Pharmacological Uses, Agarwood Grading System, and Induction Methods

Yichen Wang, Mubasher Hussain, Zhenbin Jiang, Zhaohong Wang, Jing Gao, Fengxian Ye, Runqian Mao and He Li

Molecules, 2021, 26, 7708
DOI: 10.3390/molecules26247708

Protective role of agarwood essential oil and compounds thereof in crop‐associated fungal pathogens

Jing Liu, Nuojin Cheng, Yuan Li, Xingtao Jiang, Qi Luo and Zehong Wu

Journal of Phytopathology, 2024, 172
DOI: 10.1111/jph.13251

Genome-wide investigation and expression analysis of the AP2/ERF family for selection of agarwood-related genes in Aquilaria sinensis (Lour.) Gilg

Meng-Jun Xiao, Ya-Nan Feng, Pei-Wen Sun, Yan-Hong Xu, Mei Rong, Yang Liu, Jie-Mei Jiang, Cui-Cui Yu, Zhi-Hui Gao and Jian-He Wei

Genome, 2022, 65, 443
DOI: 10.1139/gen-2022-0003

The First Report on Agarwood Formation of Aquilaria sinensis (Lour.) Spreng Induced by Fusarium equiseti

Libao Zhang, Jianglongze Yang, Ruiling Yuan, Dan Feng and Peng Chen

Plants, 2025, 14, 2272
DOI: 10.3390/plants14152272

Molecular evolution and characterization of type III polyketide synthase gene family in Aquilaria sinensis

Xupo Ding, Hao Wang, Shengzhuo Huang, Hao Zhang, Huiqin Chen, Pengwei Chen, Yuguang Wang, Zhuo Yang, Yali Wang, Shiqing Peng, Haofu Dai and Wenli Mei

Plant Physiology and Biochemistry, 2024, 210, 108571
DOI: 10.1016/j.plaphy.2024.108571

Rapid Discrimination of Aroma Components in Natural and Artificial Agarwood Incense by Static Headspace Sampling – Gas Chromatography – Mass Spectrometry (SHS-GC-MS) with Principal Component Analysis (PCA) and Partial Least Squares – Discrimination Analysis (PLS-DA)

Wenxia Sun, Shenghong Wu, Pengjian Zhu, Shimin Deng, Xin Zhou, Xiaohua Liu, Jing Zhao, Weimin Zhang, Xiaoxia Gao and Xiaoying Chen

Analytical Letters, 2022, 55, 2829
DOI: 10.1080/00032719.2022.2075006

Effects of ferrous sulfate and methyl jasmonate treatment on the content of 2-(2-phenethyl)chromones in Aquilaria sinensis

Wenli Wu, Xiaochen Sun, Iain Wilson, Luyuan Jiang, Xiaoyang Jiang, Fenjuan Shao and Deyou Qiu

Plant Cell Tiss Organ Cult, 2024, 156
DOI: 10.1007/s11240-024-02683-y

Comparative Analysis of Metabolome and Transcriptome in Different Tissue Sites of Aquilaria sinensis (Lour.) Gilg

Anjun Wang, Juan Liu and Luqi Huang

Molecules, 2024, 29, 1075
DOI: 10.3390/molecules29051075

Dimeric 2-(2-phenethyl)chromones from agarwood of Aquilaria filaria

Hong-run Yang, Pei Wang, Fang-Zheng Liu, Jing-Zhe Yuan, Cai-Hong Cai, Fei Wu, Bei Jiang, Wen-Li Mei and Hao-Fu Dai

Fitoterapia, 2023, 165, 105422
DOI: 10.1016/j.fitote.2022.105422

Chi-Nan agarwood germplasms constitute a new chemotype of Aquilaria sinensis (Lour.) Spreng

Wencheng Hou, Peiwei Liu, Yangyang Liu, Yong Kang, Yun Yang, Yuxiu Zhang, Zhihui Gao, Meng Yu, Jian Feng, Feifei Lv and Jianhe Wei

Industrial Crops and Products, 2022, 187, 115494
DOI: 10.1016/j.indcrop.2022.115494

DFT, FMO, ESP, Molecular Docking and Molecular Dynamics Simulations of Bis-2-(2-Phenethyl)Chromone as a Potential PPAR Agonist

Yingqi Qiu, Wuji Lai, Yu Feng, Qinghua Zhu, Yuanmeng Wang, Lihe Jiang, Fuhou Lei, Liqun Shen and Aiqun Wu

LOC, 2023, 20, 678
DOI: 10.2174/1570178620666230131143403

Three new dimeric 2-(2-phenethyl)chromones from the agarwood of Aquilaria malaccensis

Xian-Yun Yan, Wei Li, Hao Wang, Wen-Hua Dong, Jun Zeng, Fei Wu, Wen-Li Mei, Lin-Fu Liang and Hao-Fu Dai

Phytochemistry Letters, 2025, 66, 81
DOI: 10.1016/j.phytol.2025.02.003

Rediscovering the Therapeutic Potential of Agarwood in the Management of Chronic Inflammatory Diseases

Juman Mohammed Rasmi Alamil, Keshav Raj Paudel, Yinghan Chan, Dikaia Xenaki, Jithendra Panneerselvam, Sachin Kumar Singh, Monica Gulati, Niraj Kumar Jha, Deepak Kumar, Parteek Prasher, Gaurav Gupta, Raniya Malik, Brian George Oliver, Philip Michael Hansbro, Kamal Dua and Dinesh Kumar Chellappan

Molecules, 2022, 27, 3038
DOI: 10.3390/molecules27093038

Agarwood as a neuroprotective agent: a comprehensive review of existing evidence and potential avenues for future research

Ankur Das, Khaleda Begum, Raja Ahmed, Suraiya Akhtar, Tanisha Neog, Abhijit Sarma, Amartya Chakraborty and Sofia Banu

Phytochem Rev, 2025
DOI: 10.1007/s11101-025-10117-6

Towards sustainable agarwood production: integrating microbial interactions, anatomical changes, and metabolite biosynthesis

Yashirdisai Sampasivam, Khalisah Khairina Razman, Nor Syakila Mohd Mazlan, Kamalrul Azlan Azizan, Yogesh K Ahlawat and Roohaida Othman

Journal of Industrial Microbiology and Biotechnology, 2024, 52
DOI: 10.1093/jimb/kuaf025

Chemical Constituents and Antimicrobial Properties of the Nonresinous Heartwood of Aquilaria sinensis

Xiao-Yan Duan, Dong-Bao Hu, Hataichanok Pandith, Terd Disayathanoowat, Xue Bai, Jun Yang, Ji-Feng Luo, Angkhana Inta and Yue-Hu Wang

Chem Nat Compd, 2025, 61, 42
DOI: 10.1007/s10600-025-04571-z

Xanthone Biosynthetic Pathway in Plants: A Review

Juwairiah Remali, Idin Sahidin and Wan Mohd Aizat

Front. Plant Sci., 2022, 13
DOI: 10.3389/fpls.2022.809497

From sequences to sustainability: Exploring dipterocarp genomes for oleoresin production, timber quality, and conservation

Liuming Luo, Peng Ye, Qiongqiong Lin, Min Liu, Gang Hao, Tong Wei and Sunil Kumar Sahu

Plant Science, 2024, 346, 112139
DOI: 10.1016/j.plantsci.2024.112139

Characterization and Analysis of 2-(2-Phenylethyl)chromone Derivatives and Sesquiterpenoids from Agarwood of Four “Qi-Nan” Clones (Aquilaria sinensis) with Different Induction Times

Ming Li, Zhou Hong, Shengjie Wang, Daping Xu, Zinong Yang, Zhihui Li, Houzhen Hu and Suxin Li

Molecules, 2025, 30, 352
DOI: 10.3390/molecules30020352

Unified Approach to ent-Eudesmane-Type Terpenoid Synthesis: Total Synthesis of Sinupol and Eutyscoparin A

Koichiro Ota, Kazuo Kamaike and Hiroaki Miyaoka

Synthesis, 2022, 54, 689
DOI: 10.1055/a-1643-5729

Anti-Cancer Effect of Sesquiterpene and Triterpenoids from Agarwood of Aquilaria sinensis

Lili Chen, Yunyun Liu, Yifei Li, Wu Yin and Yongxian Cheng

Molecules, 2022, 27, 5350
DOI: 10.3390/molecules27165350

Comparative Analysis of Biological Activity of Artificial and Wild Agarwood

Sheng Ma, Mengji Qiao, Yunlin Fu, Penglian Wei, Yingjian Li and Zhigao Liu

Forests, 2021, 12, 1532
DOI: 10.3390/f12111532

Gastroprotective 2-(2-phenylethyl)chromone-sesquiterpene hybrids from the resinous wood of Aquilaria sinensis (Lour.) Gilg

Hang Zhang, Jia-Le Ma, Chuang Chang, He Ta, Yun-Fang Zhao, She-Po Shi, Yue-Lin Song, Peng-Fei Tu, Hui-Xia Huo, Jiao Zheng and Jun Li

Bioorganic Chemistry, 2023, 133, 106396
DOI: 10.1016/j.bioorg.2023.106396

Comparison of the Blood–Brain Barrier Penetration Ability and Anti-Neuroinflammatory Activity of Chromones in Two Types of Agarwood

Mengyuan Yang, Yanan Yuan, Jingfan Wei, Yifei Pei, Yuanfei Niu, Yifan Zhao, Xiangying Kong and Zhijie Zhang

Pharmaceuticals, 2025, 18, 510
DOI: 10.3390/ph18040510

Salty treatment increased bioactive compounds accumulation during agarwood development in Aquilaria sinensis trees

Tingting Yan, Ningnan Zhang, Zhou Hong, Yuan Chen and Gaiyun Li

Fitoterapia, 2024, 175, 105901
DOI: 10.1016/j.fitote.2024.105901

Seven new 2-(2-phenylethyl) chromone derivatives from agarwood of Aquilaria agallocha with inhibitory effects on nitric oxide production

Siyu Zhang, Yanqiao Xie, Leixin Song, Yu Wang, Hao Qiu, Yingbo Yang, Chunge Li, Zhengtao Wang, Zhuzhen Han and Li Yang

Fitoterapia, 2022, 159, 105177
DOI: 10.1016/j.fitote.2022.105177

Systematic investigation of the R2R3-MYB gene family in Aquilaria sinensis reveals a transcriptional repressor AsMYB054 involved in 2-(2-phenylethyl)chromone biosynthesis

Yan Yang, Jiahong Zhu, Hao Wang, Dong Guo, Ying Wang, Wenli Mei, Shiqing Peng and Haofu Dai

International Journal of Biological Macromolecules, 2023, 244, 125302
DOI: 10.1016/j.ijbiomac.2023.125302

Zizaane-Type Sesquiterpenoids and Their Rearranged Derivatives from Agarwood of an Aquilaria Plant

Jing-Zhe Yuan, Yi-Ling Yang, Wei Li, Li Yang, Hao-Fu Dai, Attila Mándi, Cai-Hong Cai, Hui-Qin Chen, Wen-Hua Dong, Tibor Kurtán, Wen-Li Mei and Hao Wang

Molecules, 2021, 27, 198
DOI: 10.3390/molecules27010198

Eight new 2-(2-phenylethyl)chromone derivatives from agarwood of Aquilaria sinensis with anti-inflammatory activity

Zhong-Hui Yang, Hong-Bin Fang, Cheng-Tian Tao, Ya-Bin Jiao and Yong-Xian Cheng

Fitoterapia, 2023, 169, 105564
DOI: 10.1016/j.fitote.2023.105564

Pharmacology and therapeutic potential of agarwood and agarwood tree leaves in periodontitis

Chen Xie, Jing-Zhe Dong, Bing-Shuai Lu, Peng-Yao Yan, Yun-Shan Zhao, Xin-Yue Ding, Cheng-En Lv and Xu Zheng

Front. Pharmacol., 2024, 15
DOI: 10.3389/fphar.2024.1468393

Effective Components and Molecular Mechanism of Agarwood Essential Oil Inhalation and the Sedative and Hypnotic Effects Based on GC-MS-Qtof and Molecular Docking

Canhong Wang, Yunyun Wang, Bao Gong, Yulan Wu, Xiqin Chen, Yangyang Liu and Jianhe Wei

Molecules, 2022, 27, 3483
DOI: 10.3390/molecules27113483

Investigating the potential anti-inflammatory mechanism of benzophenone compounds from the leaves of Aquilaria sinensi s (Lour.) Gilg based on network pharmacology and molecular docking strategies

Weihua Zhang, Baosen Yue, Feng Zhao, Yuan Zhi, Xiayin Wang, Shuai Yang, Dan Sun, Nan Lv and Xiaojing Wu

Toxicology Mechanisms and Methods, 2023, 33, 656
DOI: 10.1080/15376516.2023.2223291

Eremophilane sesquiterpenes from agarwood of Aquilaria agallocha with neuroprotective effect

Yanqiao Xie, Siyu Zhang, Tianqi Chen, Chunge Li, Ruonan Tong, Hong Xu, Yingbo Yang, Zhuzhen Han, Zhengtao Wang and Li Yang

Phytochemistry, 2025, 237, 114527
DOI: 10.1016/j.phytochem.2025.114527

Characterization of an α‐ketoglutarate‐dependent oxygenase involved in converting 2‐(2‐phenylethyl)chromones into 2‐styrylchromones in agarwood

Mingliang Zhang, Jiangping Fan, Zekun Zhang, Mengrong Niu, Xinyu Mi, Hailing Qiu, Jun Li, Xiao Liu, Juan Wang, Xiaohui Wang, Pengfei Tu and She‐Po Shi

The Plant Journal, 2025, 121
DOI: 10.1111/tpj.70068

Comprehensive Analysis of NAC Transcription Factors Reveals Their Evolution in Malvales and Functional Characterization of AsNAC019 and AsNAC098 in Aquilaria sinensis

Zhuo Yang, Wenli Mei, Hao Wang, Jun Zeng, Haofu Dai and Xupo Ding

IJMS, 2023, 24, 17384
DOI: 10.3390/ijms242417384

Extraction of secondary metabolites from endophytic fungus Colletotrichum sp. A885: Spectroscopic characterization, anti-inflammatory properties and molecular docking studies

Jianpeng Zhang, Yuchan Chen, Xuan Ma, Ziling Tan, Saini Li, Hongxin Liu and Weimin Zhang

Journal of Molecular Structure, 2025, 1345, 143064
DOI: 10.1016/j.molstruc.2025.143064

On-Site Analysis and Rapid Authentication of Valuable Agarwood Samples by Paper Capillary Spray Miniature Mass Spectrometry

Yanqiao Xie, Shengqi Huang, Qian Zhang, Siyu Zhang, Zhuzhen Han, Jinliang Yu, Xingyu Wang, Kaixian Chen, Zhengtao Wang, Linnan Li and Li Yang

J. Anal. Test., 2025, 9, 61
DOI: 10.1007/s41664-024-00331-0

Nerolidol reduces depression-like behavior in mice and suppresses microglia activation by down-regulating DNA methyltransferase 1

Guangcai Zhang, Xiaohui Zhou, Qifan Feng, Weihua Ke, Jiahui Pan, Haiying Zhang, Yixian Luan and Beibei Lei

NeuroReport, 2024, 35, 457
DOI: 10.1097/WNR.0000000000002029

Two unprecedented 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones with anti-Helicobacter pylori activity from agarwood of Aquilaria sinensis 'Reke 1'

Ke-Xin Qin, Hao Wang, Li Yang, Yan-Mei Wei, Cai-Hong Cai, Hui-Qin Chen, Wen-Hua Dong, Wei Li, Xian-Yun Yan, Jun Zeng, Wen-Li Mei, Jie Jian and Haofu Dai

Phytochemistry Letters, 2025, 66, 77
DOI: 10.1016/j.phytol.2025.01.1002

Seven New 2-(2-Phenylethyl) Chromone Derivatives from Agarwood of Aquilaria Agallocha with Inhibitory Effects on Nitric Oxide Production

Siyu Zhang, Yanqiao Xie, Leixin Song, Yu Wang, Hao Qiu, Yingbo Yang, Chunge Li, Zhengtao Wang, Zhuzhen Han and Li Yang

SSRN Journal, 2022
DOI: 10.2139/ssrn.4007110

Aquilariperoxide A, a Sesquiterpene Dimer from Agarwood of Aquilaria sinensis with Dual Antitumor and Antimalarial Effects

Xiao-Ling Huang, Dan Cai, Peng Gao, Ji-Gang Wang and Yong-Xian Cheng

J. Org. Chem., 2023, 88, 8352
DOI: 10.1021/acs.joc.3c00372

CYP82G1 Enzyme Functions as Chromone Hydroxylase in the Biosynthesis of 6‐Hydroxy‐2‐(2‐Phenylethyl)chromone in Aquilaria sinensis

Wenli Wu, Tingting Yan, Yuanyuan Zhao, Xuan Zhang, Iain Wilson, Gaiyun Li, Hao Wang, Wenli Mei, Ruibo Wu, Xiaochen Sun, Luyuan Jiang, Xiaoyang Jiang, Fenjuan Shao and Deyou Qiu

Plant Biotechnology Journal, 2025
DOI: 10.1111/pbi.70327

The chromosome‐scale genomes of Dipterocarpus turbinatus and Hopea hainanensis (Dipterocarpaceae) provide insights into fragrant oleoresin biosynthesis and hardwood formation

Sibo Wang, Hongping Liang, Hongli Wang, Linzhou Li, Yan Xu, Yang Liu, Min Liu, Jinpu Wei, Tao Ma, Cheng Le, Jinlong Yang, Chengzhong He, Jie Liu, Jianming Zhao, Yuxian Zhao, Michael Lisby, Sunil Kumar Sahu and Huan Liu

Plant Biotechnology Journal, 2022, 20, 538
DOI: 10.1111/pbi.13735

Characterization of Cinnamomum kanehirae Extract-Stimulated Triterpenoids Synthesis in Submerged Fermentation of Antrodia camphorata via Untargeted Metabolomics

Zhi-Shan Luo, Zhen-Ming Lu, Miao-Miao Hu, Xin-Yang Li, Guo-Qiang Xu, Jin-Song Gong, Jin-Song Shi and Zheng-Hong Xu

J. Agric. Food Chem., 2023, 71, 9175
DOI: 10.1021/acs.jafc.3c01508

A BIBLIOMETRIC ANALYSIS OF AGARWOOD RESEARCH AND THE IMPACT OF CITES LISTING

J.R. Chen, M.S. Hishamuddin, B.M. Hung, R Mohammed and S.Y. Lee

THE JAPS, 2024, 34, 817
DOI: 10.36899/JAPS.2024.4.0768

Sesquiterpene-enriched extract of Chinese agarwood (Aquilaria sinensis) alleviates bile reflux gastritis through suppression of gastric mucosal cell apoptosis via the Wnt/β-catenin signaling pathway

Jiale Ma, Xueping Pang, Weigang Xue, Junjiao Wang, Huixia Huo, Maoyuan Zhao, Yangli Huang, Ziyu Yin, Yun Gao, Yunfang Zhao, Jun Li and Jiao Zheng

Journal of Ethnopharmacology, 2025, 338, 119037
DOI: 10.1016/j.jep.2024.119037

Synthesis and pharmacological activity evaluation of 2-(2-Phenylethyl)chromone analogues: The principal components in agarwood

Mingliang Zhang, Mengrong Niu, Jiangping Fan, Zihan Lu, Zhixiang Zhu, Bowen Gao and She-Po Shi

Fitoterapia, 2025, 180, 106296
DOI: 10.1016/j.fitote.2024.106296

In-depth characterization of minor 2-(2-phenylethyl)chromone oligomers from Chinese agarwood by integrating offline two-dimensional liquid chromatography and hybrid ion trap time-of-flight mass spectrometry

Huixia Huo, Hang Zhang, Huiting Liu, Jiale Ma, Qian Zhang, Yunfang Zhao, Jiao Zheng, Pengfei Tu, Yuelin Song and Jun Li

Chin Med, 2025, 20
DOI: 10.1186/s13020-025-01073-6

Three new 2-(2-phenylethyl)chromones from ‘Chong-lou’ agarwood of Aquilaria sinensis

Xin Su, Cai-Hong Cai, Wen-Hua Dong, Cui-Juan Gai, Ya-Li Wang, Wen-Li Mei, Xing-Lian Xu, Hao-Fu Dai and Hui-Qin Chen

Phytochemistry Letters, 2022, 51, 86
DOI: 10.1016/j.phytol.2022.07.009

Identification of O-Methyltransferases Potentially Contributing to the Structural Diversity of 2-(2-Phenylethyl)chromones in Agarwood

Bingbing Wang, Yan Hai, Le Zhang, Mingliang Zhang, Ning Ding, Jiangping Fan, Beibei Zhang, Zekun Zhang, Juan Wang, Xiaohui Wang, Jun Li, Pengfei Tu, Xiao Liu and She-Po Shi

J. Agric. Food Chem., 2024, 72, 13297
DOI: 10.1021/acs.jafc.4c02440

Agarwood—The Fragrant Molecules of a Wounded Tree

Pooja Shivanand, Nurul Fadhila Arbie, Sarayu Krishnamoorthy and Norhayati Ahmad

Molecules, 2022, 27, 3386
DOI: 10.3390/molecules27113386

Anatomical and histochemical characterization of some highly medicinal plants as a tool for quality control

Ghulam Dastagir, Farrukh Hussain and Noor Ul Uza

Microscopy Res & Technique, 2023, 86, 966
DOI: 10.1002/jemt.24369

Physiological and Endophytic Fungi Changes in Grafting Seedlings of Qi-Nan Clones (Aquilaria sinensis)

Xiaoying Fang, Xiaofei Li, Qilei Zhang, Houzhen Hu, Zhou Hong, Xiaojin Liu, Zhiyi Cui and Daping Xu

Forests, 2024, 15, 106
DOI: 10.3390/f15010106

Effects of different clones and inducing time on agarwood quality in grafted Qi-Nan Aquilaria sinensis (Lour.) spreng

Ming Li, Zinong Yang, Zhou Hong, Daping Xu, ZhiHui Li, Shengjie Wang and Pankaj Bhardwaj

PLoS One, 2025, 20, e0327514
DOI: 10.1371/journal.pone.0327514

Comparative Morphological, Anatomical and Physiological Analyses Explain the Difference of Wounding-Induced Agarwood Formation between Ordinary Agarwood Nongrafted Plants and Five Grafted Qi-Nan Clones (Aquilaria sinensis)

Xiaofei Li, Zhiyi Cui, Xiaojin Liu, Zhou Hong, Peng Zhang and Daping Xu

Forests, 2022, 13, 1618
DOI: 10.3390/f13101618

Multispectral Image Determination of Water Content in Aquilaria sinensis Based on Machine Learning

Peng Wang, Yi Wu, Xuefeng Wang, Mengmeng Shi, Xingjing Chen and Ying Yuan

Forests, 2023, 14, 1144
DOI: 10.3390/f14061144

Saprophytic Bacillus Accelerates the Release of Effective Components in Agarwood by Degrading Cellulose

Huizhen Yang, Runying He, Yao Cui, Ying Li and Xizhen Ge

Molecules, 2022, 27, 1428
DOI: 10.3390/molecules27041428

Discovery of Biomarkers and Potential Mechanisms of Agarwood Incense Smoke Intervention by Untargeted Metabolomics and Network Pharmacology

Meiyue Dong, Haitao Du, Xueling Li, Ling Zhang, Xiaoming Wang, Zhenguo Wang and Haiqiang Jiang

DDDT, 2022, Volume 16, 265
DOI: 10.2147/DDDT.S348028

Filarones A and B, new anti-inflammatory dimeric 2-(2-phenethyl)chromones from agarwood of Aquilaria filaria

Fang-Zheng Liu, Hao Wang, Wei Li, Li Yang, Jin-Ling Yang, Jing-Zhe Yuan, Yan-Mei Wei, Bei Jiang, Wen-Li Mei and Hao-Fu Dai

Phytochemistry Letters, 2021, 46, 11
DOI: 10.1016/j.phytol.2021.09.008

The Effect of Chinese Agarwood Essential Oil with Cyclodextrin Inclusion against PCPA-Induced Insomnia Rats

Yinfang Lai, Liping Hua, Jiali Yang, Juewen Xu, Junduo Chen, Shuangshuang Zhang, Shunyao Zhu, Jingjing Li and Senlin Shi

Molecules, 2023, 28, 635
DOI: 10.3390/molecules28020635

2-(2-Phenylethyl)chromone dimers as melanin production inhibitors from agarwood of Gyrinops walla Gaertn

Le-Yao Chen, Wen-Li Mei, Li Yang, Fei Wu, Cai-Hong Cai, Jing-Zhe Yuan, Hui-Qin Chen and Hao-Fu Dai

Industrial Crops and Products, 2024, 222, 120147
DOI: 10.1016/j.indcrop.2024.120147

Optimization and induction effect evaluation of complex inducer of Aquilaria sinensis based on factorial design

Qiuyue Ding, Baoyi Qin, Shimin Deng, Jie Chen, Ziwei Liu, Weiping Zhou, Xiaoying Chen, Weimin Zhang, Xin Zhou and Xiaoxia Gao

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-04230-x

Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality control, conservation status and future prospective

Anmol, Gaurav Aggarwal, Mehak Sharma, Raman Singh, Shivani and Upendra Sharma

Journal of Ethnopharmacology, 2024, 320, 117385
DOI: 10.1016/j.jep.2023.117385

Characteristic quality analysis for biologically induced agarwood columns in Aquilaria sinensis

Zeqing Wu and Liangwen Yu

Environmental Research, 2023, 235, 116633
DOI: 10.1016/j.envres.2023.116633

Essential oil from Aquilaria spp. (agarwood): a comprehensive review on the impact of extraction methods on yield, chemical composition, and biological activities

Xin Wang, Sook Wah Chan, Nallammai Singaram, Ming-Li Teoh, Siau Hui Mah and Chung Yeng Looi

Journal of Essential Oil Research, 2025, 37, 110
DOI: 10.1080/10412905.2024.2447706

Three candidate 2-(2-phenylethyl)chromone-producing type III polyketide synthases from Aquilaria sinensis (Lour.) Gilg have multifunctions synthesizing benzalacetones, quinolones and pyrones

Mengjun Xiao, Binbin Wang, Yanan Feng, Peiwen Sun, Mei Rong, Yangyang Liu, Deli Chen, Feifei Lv, Zhihui Gao and Jianhe Wei

Industrial Crops and Products, 2022, 186, 115263
DOI: 10.1016/j.indcrop.2022.115263

Mitigating fatigue in long COVID patients with MYPplus: a clinical observation

Yu-Jin Choi, Jin-Seok Lee, Jin-Yong Joung, Seung-Ju Hwang, Young-Yil Kim and Chang-Gue Son

BMC Infect Dis, 2025, 25
DOI: 10.1186/s12879-025-10984-6

Biosynthesis and Its Regulatory Mechanisms of 2-(2-Phenylethyl)chromones in Agarwood

Wenli Wu, Xiaoyang Jiang, Luyuan Jiang, Iain Wilson, Fenjuan Shao and Deyou Qiu

Plants, 2025, 14, 1012
DOI: 10.3390/plants14071012

Development and Application of SSR Markers for Aquilaria sinensis on the Basis of Whole-Genome Resequencing Data

Yu Chen, Kunlin Wu, Jieru Xu, Shenghe Zhao, Zhihua Tu, Dandan Rao, Beibei Chen, Nanbo Jiao, Jinhui Chen and Xiaona Dong

Plants, 2025, 14, 1323
DOI: 10.3390/plants14091323

Comprehensive Comparisons between Grafted Kynam Agarwood and Normal Agarwood on Traits, Composition, and In Vitro Activation of AMPK

Fengming Chen, Yu Huang, Lu Luo, Qiaochu Wang, Nanxi Huang, Zhijie Zhang and Zhen Li

Molecules, 2023, 28, 1667
DOI: 10.3390/molecules28041667

Bioassay-guided isolation of cytotoxic constituents from the flowers of Aquilaria sinensis

Jun Yang, Dong-Bao Hu, Meng-Yuan Xia, Ji-Feng Luo, Xing-Yu Li and Yue-Hu Wang

Nat. Prod. Bioprospect., 2022, 12
DOI: 10.1007/s13659-022-00334-3

Resequencing insights into the genetic characteristic and development of molecular markers for Chi-Nan germplasm (Aquilaria sinensis)

Feifei Lv, Peiwen Sun, Yun Yang, Xiaohong Fan, Yong Kang, Peiwei Liu, Yanhong Xu and Jianhe Wei

Industrial Crops and Products, 2025, 230, 121055
DOI: 10.1016/j.indcrop.2025.121055

Agarwood oil nanoemulsion counteracts LPS-induced inflammation and oxidative stress in RAW264.7 mouse macrophages

Raniya Malik, Keshav Raj Paudel, Bikash Manandhar, Gabriele De Rubis, Jessie Shen, Somdutt Mujwar, Thakur Gurjeet Singh, Sachin Kumar Singh, Gaurav Gupta, Jon Adams, Ronan MacLoughlin, Brian Gregory George Oliver, Philip Michael Hansbro, Dinesh Kumar Chellappan and Kamal Dua

Pathology - Research and Practice, 2023, 251, 154895
DOI: 10.1016/j.prp.2023.154895

Secondary Metabolites from the Endophytic Fungus Letendraea helminthicola A820 with Anti‐Inflammatory Activity

Jianpeng Zhang, Ziling Tan, Yuchan Chen, Chunan Li, Saini Li, Hongxin Liu, Weimin Zhang and Hanjing Yan

Chemistry & Biodiversity, 2025, 22
DOI: 10.1002/cbdv.202402114

2-(2-Phenylethyl)chromones increase in Aquilaria sinensis with the formation of agarwood

Yuanyuan Sun, Meiran Wang, Meng Yu, Jian Feng, Jianhe Wei and Yangyang Liu

Front. Plant Sci., 2024, 15
DOI: 10.3389/fpls.2024.1437105

Identification of aroma‐active components from cultivated agarwood ‘Qi‐Nan’ based on GC‐O‐MS combined with aroma extract dilution analysis

Zhen Yu, Wenhua Dong, Yali Wang, Wei Li, Zhiyong Guo, Wenli Mei and Haofu Dai

Flavour & Fragrance J, 2023, 38, 392
DOI: 10.1002/ffj.3754

Chemical composition and bioactivity variability of two-step extracts derived from traditional and “QiNan” agarwood (Aquilaria spp.)

Sheng Ma, Tingting Yan, Yuan Chen and Gaiyun Li

Fitoterapia, 2024, 176, 106012
DOI: 10.1016/j.fitote.2024.106012

Sesquiterpenoids in Agarwood: Biosynthesis, Microbial Induction, and Pharmacological Activities

Xinghao Zhang, Lan Xiang Wang, Ruirui Hao, Jing jing Huang, Meisam Zargar, Mo-Xian Chen, Fu-Yuan Zhu and Hao-fu Dai

J. Agric. Food Chem., 2024, 72, 23039
DOI: 10.1021/acs.jafc.4c06383

New Aquilariomyces and Mangifericomes species (Pleosporales, Ascomycota) from Aquilaria spp. in China

Tian-Ye Du, Samantha C. Karunarathna, Kevin D. Hyde, Somrudee Nilthong, Ausana Mapook, Dong-Qin Dai, Kunhiraman C. Rajeshkumar, Abdallah M. Elgorban, Li-Su Han, Hao-Han Wang and Saowaluck Tibpromma

MC, 2025, 112, 103
DOI: 10.3897/mycokeys.112.139831

Sesquiterpenoid-Chromone Heterohybrids from Agarwood of Aquilaria sinensis as Potent Specific Smad3 Phosphorylation Inhibitors

Xiao-Ling Huang, Ye-Ting Zhou, Yong-Ming Yan and Yong-Xian Cheng

J. Org. Chem., 2022, 87, 7643
DOI: 10.1021/acs.joc.2c00145

Anti-inflammatory 5,6,7,8-tetrahydro-2-(2-phenylethyl) chromone derivatives from the stems of Aquilaria sinensis

Xia Liu, Min Yu, Jie Chen, Bin Hu, Jia-Bo Huang, Wei-Qun Yang and Zhong-Xiang Zhao

Fitoterapia, 2025, 180, 106312
DOI: 10.1016/j.fitote.2024.106312

The key odor-active components differed in cultured agarwood from two germplasms of Aquilaria. sinensis trees

Tingting Yan, Zekun Hu, Yuan Chen, Sheng Yang, Peng Zhang, Zhou Hong and Gaiyun Li

Industrial Crops and Products, 2023, 194, 116185
DOI: 10.1016/j.indcrop.2022.116185

Chemical Composition and Potential Properties in Mental Illness (Anxiety, Depression and Insomnia) of Agarwood Essential Oil: A Review

Xiqin Chen, Canhong Wang, Qingqin He, Jian Feng, Deli Chen, Jianhe Wei and Yangyang Liu

Molecules, 2022, 27, 4528
DOI: 10.3390/molecules27144528

Chemical Investigation on the Volatile Part of the CO2 Supercritical Fluid Extract of Infected Aquilaria sinensis (Chinese Agarwood)

Marko Z. Mladenović, Ou Huang, Bo Wang, Alexandre Ginestet, Didier Desbiaux and Nicolas Baldovini

Molecules, 2024, 29, 2297
DOI: 10.3390/molecules29102297

Chios Mastic Gum: A Promising Phytotherapeutic for Cardiometabolic Health

Sarah A. Blomquist and Maria Luz Fernandez

Nutrients, 2024, 16, 2941
DOI: 10.3390/nu16172941

Genome-wide detection and classification of terpene synthase genes in Aquilaria agallochum

Ankur Das, Khaleda Begum, Suraiya Akhtar, Raja Ahmed, Ram Kulkarni and Sofia Banu

Physiol Mol Biol Plants, 2021, 27, 1711
DOI: 10.1007/s12298-021-01040-z

Expression analysis of sesquiterpenes biosynthesis-related genes in Aquilaria sinensis during bark regeneration

Mengyao Yan, Zhongliang Lu, Panjing Li, Minggen Xie, Guangzhen Zhou and Yinglang Wan

T, 2025, 4, 0
DOI: 10.48130/tp-0024-0048

Two unprecedented 2-(2-phenethyl)chromone dimers from red soil agarwood of Aquilaria crassna

Hong-Xing Chai, Hao Wang, Jun Zeng, Wen-Hua Dong, Wen-Li Mei, Bei Jiang, Wei Li and Hao-Fu Dai

Phytochemistry Letters, 2024, 59, 87
DOI: 10.1016/j.phytol.2023.12.006

Eudesmane-type and agarospirane-type sesquiterpenes from agarwood of Aquilaria agallocha

Yanqiao Xie, Leixin Song, Chunge Li, Yingbo Yang, Siyu Zhang, Hong Xu, Zhengtao Wang, Zhuzhen Han and Li Yang

Phytochemistry, 2021, 192, 112920
DOI: 10.1016/j.phytochem.2021.112920

Manqin Huang, Sheng Ma, Mengji Qiao, Yunlin Fu and Yingjian Li

J. Agric. Food Chem., 2023, 71, 15620
DOI: 10.1021/acs.jafc.3c04322

Chemical analysis of different parts from agarwood columns by artificially agarwood-inducing method based on GC–MS and UPLC-TOF-MS

Jiao Li, Liangwen Yu, Youcheng Liang, Baoheng Lan, Yingting Chen, Qianqian Wang and Zeqing Wu

Fitoterapia, 2024, 178, 106156
DOI: 10.1016/j.fitote.2024.106156

The Characteristic Fragrant Sesquiterpenes and 2-(2-Phenylethyl)chromones in Wild and Cultivated “Qi-Nan” Agarwood

Li Yang, Jin-Ling Yang, Wen-Hua Dong, Ya-Li Wang, Jun Zeng, Jing-Zhe Yuan, Hao Wang, Wen-Li Mei and Hao-Fu Dai

Molecules, 2021, 26, 436
DOI: 10.3390/molecules26020436

Chemical and Bioactivity Diversity of 2‐(2‐Phenylethyl)chromones in Agarwood: A Review

Meng Yu, Qing‐Qin He, Xi‐Qin Chen, Jian Feng, Jian‐He Wie and Yang‐Yang Liu

Chemistry & Biodiversity, 2022, 19
DOI: 10.1002/cbdv.202200490

Comprehensive investigation of the C2H2-type zinc finger protein transcription factor family in Aquilaria sinensis reveals the involvement of AsZFP9 in sesquiterpene biosynthesis

Yuji Li, Dong Guo, Hao Wang, Ying Wang, Shiqing Peng, Haofu Dai, Wenli Mei and Jiahong Zhu

International Journal of Biological Macromolecules, 2025, 318, 145119
DOI: 10.1016/j.ijbiomac.2025.145119

Cloning and functional analysis of novel terpene synthase genes from Aquilaria sinensis and insights into the biosynthesis of sesquiterpene

Guoqiong Li, Yi Chen, Xin Wen, Xin Geng, Sai Zhang, Yimian Ma, Chengmin Yang, Liping Zhang, Yuan Li and Zheng Zhang

Industrial Crops and Products, 2024, 217, 118835
DOI: 10.1016/j.indcrop.2024.118835

Anatomical, chemical and endophytic fungal diversity of a Qi-Nan clone of Aquilaria sinensis (Lour.) Spreng with different induction times

Xiaofei Li, Xiaoying Fang, Zhiyi Cui, Zhou Hong, Xiaojin Liu, Gaiyun Li, Houzhen Hu and Daping Xu

Front. Plant Sci., 2024, 15
DOI: 10.3389/fpls.2024.1320226

Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy

Yanan Wang, Qing Liu, Helong Quan, Seong-Gook Kang, Kunlun Huang and Tao Tong

Nutrients, 2021, 13, 1914
DOI: 10.3390/nu13061914

Optimized green extraction of agarwood essential oil using custom natural deep eutectic solvents: Chemical analysis and bioactivity evaluation

Zixiao Jiang, Wencheng Hou, Jian Feng, Shunan Zhang, Meiran Wang and Yangyang Liu

LWT, 2024, 214, 117125
DOI: 10.1016/j.lwt.2024.117125

Feeding Aquilaria sinensis Leaves Modulates Lipid Metabolism and Improves the Meat Quality of Goats

Li Min, Gang Wang, Xiong Tong, Huaigu Yang, Hao Sun, Zhifei Zhang, Bin Xu, Dagang Li, Sheng Zhang and Guanghong Li

Foods, 2023, 12, 560
DOI: 10.3390/foods12030560

Identification of a diarylpentanoid-producing polyketide synthase in the biosynthesis of 2-(2-phenylethyl)chromones in agarwood

Hiroyuki Morita, Yuan-E Lee and She-Po Shi

J Nat Med, 2023, 77, 667
DOI: 10.1007/s11418-023-01743-5

Cytotoxicities of cucurbitacins from the stem bark of Aquilaria sinensis

Xiao-Yu Chen, Jun Yang, Xing-Zhi Yang, Ji-Feng Luo, Xiao-Yan Duan, Dong-Bao Hu and Yue-Hu Wang

Phytochemistry Letters, 2024, 60, 190
DOI: 10.1016/j.phytol.2024.02.011

Utilizing metabolomics and network analysis to explore the effects of artificial production methods on the chemical composition and activity of agarwood

Wencheng Hou, Jian Feng, Yuanyuan Sun, Xiqin Chen, Yangyang Liu and Jianhe Wei

Front. Pharmacol., 2024, 15
DOI: 10.3389/fphar.2024.1357381

In vitro Antioxidant and Antibacterial Activities, Bioactive Compounds, Organic Acids, Sugars, Micro- and Macro-elements of Aquilaria agallocha Root Organic Extracts

Hatice Feyza Akbulut

J. Oleo Sci., 2025, 74, 79
DOI: 10.5650/jos.ess24228

2-(2-Phenylethyl)chromone-Sesquiterpene Hybrids from Agarwood of Aquilaria sinensis: Characterization and Biological Activity Evaluation

Guan-Hua Xu, Ya-Li Wang, Hao Wang, Hui-Qin Chen, Wen-Hua Dong, Sheng-Zhuo Huang, Cai-Hong Cai, Jing-Zhe Yuan, Wen-Li Mei, Shou-Bai Liu and Hao-Fu Dai

Molecules, 2025, 30, 1984
DOI: 10.3390/molecules30091984

Evaluation of biotic and abiotic stressors to artificially induce agarwood production in Gyrinops versteegii (Gilg.) Domke seedlings

Ahmad Faizal, Dina Hermawaty, Eliana Junita, Andira Rahmawati, Alda Wydia Prihartini Azar, Maria Masitho Makajanma and Maman Turjaman

Symbiosis, 2022, 86, 229
DOI: 10.1007/s13199-022-00835-2

Two unprecedented neuroprotective 2-(2-phenylethyl)chromone derivatives from cultivated “Qi-Nan” agarwood of Aquilaria sinensis

Lin Zhang, Hao Wang, Wen-Hua Dong, Jun Zeng, Li Yang, Wei Li, Hui-Qin Chen, Jing-Zhe Yuan, Cai-Hong Cai, Zhen-Yu Li, Wen-Li Mei and Hao-Fu Dai

Phytochemistry Letters, 2024, 60, 207
DOI: 10.1016/j.phytol.2024.02.015

Screening and Site Adaptability Evaluation of Qi-Nan Clones (Aquilaria sinensis) in Southern China

Houzhen Hu, Daping Xu, Xiaofei Li, Xiaoying Fang, Zhiyi Cui, Xiaojin Liu, Jian Hao, Yu Su and Zhou Hong

Forests, 2024, 15, 1753
DOI: 10.3390/f15101753

Combining Enzyme and Photoredox Catalysis for the Construction of 3-Aminoalkyl Chromones

Jia-Yu Hu, Zong-Bo Xie, Juan Tang, Zhang-Gao Le and Zhi-Qiang Zhu

J. Org. Chem., 2022, 87, 14965
DOI: 10.1021/acs.joc.2c01977

Ethnobotanical study of traditional medicinal plants used by the Miao people in Hainan, China

Tian-Liang, Shengzhuo Huang, Jun Zeng, Shoubai Liu, Honglei Jin, Yijun Chen, Battseren Tsambaa, Urtnasan Mandakh, Xilong Zheng, Wenli Mei, Almaz Borjigidai and Haofu Dai

J Ethnobiology Ethnomedicine, 2025, 21
DOI: 10.1186/s13002-025-00795-z

Phytochemistry and Cytotoxic Activity of Aquilaria crassna Pericarp on MDA-MB-468 Cell Lines

Thao Thi Thu Nguyen, Thu Nguyen Minh Pham, Chi Thi Ngoc Nguyen, Tuyen N. Truong, Cleo Bishop, Nam Q. H. Doan and Thi Hong Van Le

ACS Omega, 2023, 8, 42356
DOI: 10.1021/acsomega.3c04656

Six unprecedented 2-(2-phenethyl)chromone dimers from agarwood of Aquilaria filaria

Yuan Wei, Wen-Hua Dong, Wei Li, Jun Zeng, Hui-Qin Chen, Sheng-Zhuo Huang, Li Yang, Wen-Li Mei, Ya-Li Wang, Zhi-Yong Guo, Hao-Fu Dai and Hao Wang

Fitoterapia, 2024, 175, 105905
DOI: 10.1016/j.fitote.2024.105905

The odorants profiles and bioactivities of agarwood essential oils from two germplasm of Aquilaria sinensis trees by different extraction methods

Tingting Yan, Sheng Ma, Yuan Chen and Gaiyun Li

Industrial Crops and Products, 2024, 216, 118719
DOI: 10.1016/j.indcrop.2024.118719

Structural, defense enzyme activity and chemical composition changes in the xylem of Aquilaria sinensis during fungus induction

Tianfeng Liu, Yuxin Liu, Yunlin Fu, Mengji Qiao, Penglian Wei, Zhigao Liu and Yingjian Li

Industrial Crops and Products, 2024, 208, 117804
DOI: 10.1016/j.indcrop.2023.117804

An Enantiospecific Synthesis of 5-epi-α-Bulnesene

Jiarui Zong and Jeremy Robertson

Molecules, 2023, 28, 3900
DOI: 10.3390/molecules28093900

Antioxidant aromatic compounds from Amomum villosum and target prediction of active ingredients

Junming Liang, Yang Xu, Jinxia Chen, Zhiruo Zhang, Hui Wang, Kexin Liu, Dejuan Sun, Hua Li and Lixia Chen

Bioorganic Chemistry, 2024, 147, 107375
DOI: 10.1016/j.bioorg.2024.107375

Biosynthesis and Medicinal Value of Flavonoids and Chromones in Agarwood

Chen-Chen Fu, Bao-Xing Huang, Xinghao Zhang, Jian-Li Zhou, Shu-Yi Mao, Tai-Ping Fan, Jian-Hua Zhang, Shan-Shan Wang, Mo-Xian Chen and Fu-Yuan Zhu

J. Agric. Food Chem., 2025, 73, 16049
DOI: 10.1021/acs.jafc.5c02632

An Updated Review of Aquilaria Species: Distribution, Chemical Constituents and Authentication Methods

Yen Van Thi, Thuy Duong Thanh, Tuan Doan Quoc, Dien Dinh, Thang Tran Nam, Trung Nguyen Quoc and Chu Ha Duc

Asian J. of Plant Sciences, 2024, 23, 146
DOI: 10.3923/ajps.2024.146.167

Advancements in agarwood germplasm resources, quality evaluation, and formation mechanism

Hao WANG, XuPo DING, Jun ZENG, JiaHong ZHU, WenHua DONG, HuiQin CHEN, ShengZhuo HUANG, Wei LI, WenLi MEI and HaoFu DAI

Sci. Sin.-Vitae, 2024, 54, 1885
DOI: 10.1360/SSV-2023-0291

Aquilaria sinensis leaf tea affects the immune system and increases sleep in zebrafish

Xiaohui Tan, Liping Wang, William Kojo Smith, Huayan Sun, Lingyun Long, Liyan Mao, Qiuwei Huang, Huifang Huang and Zhaomin Zhong

Front. Pharmacol., 2023, 14
DOI: 10.3389/fphar.2023.1246761

Effects of Different Levels of Physical Damage Combined with Fungal Induction on Agarwood Formation

Weiwei Zhao, Xiaochen Song, Zaizhi Zhou, Gaofeng Liu, Qingqing Zhang and Shengjiang Pang

Forests, 2024, 15, 168
DOI: 10.3390/f15010168

An integrated chemical characterization based on FT-NIR, GC–MS and LC-MS for the comparative metabolite profiling of wild and cultivated agarwood

Cheng Yao, Luming Qi, Furong Zhong, Na Li and Yuntong Ma

Journal of Chromatography B, 2022, 1188, 123056
DOI: 10.1016/j.jchromb.2021.123056

Bi-2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria filaria in the Philippines

Hong-Run Yang, Hao Wang, Pei Wang, Fang-Zheng Liu, Hong-Xing Chai, Cai-Hong Cai, Li Yang, Jing-Zhe Yuan, Bei Jiang, Wen-Li Mei and Hao-Fu Dai

Phytochemistry, 2024, 222, 114108
DOI: 10.1016/j.phytochem.2024.114108

Rapid screening and characterization of 2-(2-phenylethyl)chromones in agarwood by UHPLC-Q-Exactive Orbitrap-MS

Zhen Du, Huanjun Wang, Xueling Li, Meiyue Dong, Bingqing Chi, Zhenhua Tian, Zhenguo Wang and Haiqiang Jiang

Food Chemistry, 2023, 424, 136400
DOI: 10.1016/j.foodchem.2023.136400

Identification of sesquiterpene synthase genes in the genome of Aquilaria sinensis and characterization of an α-humulene synthase

Jiadong Ran, Yuan Li, Xin Wen, Xin Geng, Xupeng Si, Liping Zhang, Yimian Ma and Zheng Zhang

J. For. Res., 2023, 34, 1117
DOI: 10.1007/s11676-022-01542-w

LC-MS-guided isolation of 2-(2-phenylethyl)chromone dimers from red soil agarwood of Aquilaria crassna

Di He, Wen-Hua Dong, Wei Li, Li Yang, Jing-Zhe Yuan, Cui-Juan Gai, Cai-Hong Cai, Hao-Fu Dai, Hao Wang and Wen-Li Mei

Fitoterapia, 2022, 158, 105162
DOI: 10.1016/j.fitote.2022.105162

Identification and characterization of two O-methyltransferases involved in biosynthesis of methylated 2-(2-phenethyl)chromones in agarwood

Wenli Wu, Tingting Yan, Xiaochen Sun, Iain Wilson, Gaiyun Li, Zhou Hong, Fenjuan Shao, Deyou Qiu and Karl-Josef Dietz

Journal of Experimental Botany, 2024, 75, 3452
DOI: 10.1093/jxb/erae130

Systematic evolution of bZIP transcription factors in Malvales and functional exploration of AsbZIP14 and AsbZIP41 in Aquilaria sinensis

Hao Zhang, Xupo Ding, Hao Wang, Huiqin Chen, Wenhua Dong, Jiahong Zhu, Jian Wang, Shiqing Peng, Haofu Dai and Wenli Mei

Front. Plant Sci., 2023, 14
DOI: 10.3389/fpls.2023.1243323

Agarperoxinols A and B: Two Unprecedented Tricyclic 6/6/7 Rearranged Humulene-Type Sesquiterpenoids That Attenuated the Neuroinflammation in LPS-Stimulated Microglial Models

Chi Thanh Ma, Sang Bin Lee, In Ho Cho, Jae Sik Yu, Tianqi Huang, Tae Min Lee, Tu Loan Ly, Sung Won Kwon, Jeong Hill Park and Hyun Ok Yang

ACS Omega, 2023, 8, 43873
DOI: 10.1021/acsomega.3c05783

Seven new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla

Leyao Chen, Huiqin Chen, Caihong Cai, Jingzhe Yuan, Cuijuan Gai, Shoubai Liu, Wenli Mei and Haofu Dai

Fitoterapia, 2023, 165, 105421
DOI: 10.1016/j.fitote.2022.105421

Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery

Kouharu Otsuki and Wei Li

J Nat Med, 2023, 77, 625
DOI: 10.1007/s11418-023-01713-x

Inducing Aquilaria sinensis (Lour.) Spreng “Qinan” Agarwood Formation with Chemical Reagents

Qilei Zhang, Xiaojin Liu, Xiaofei Li, Xiaoying Fang, Yongmei Xiong and Daping Xu

Agronomy, 2024, 14, 1727
DOI: 10.3390/agronomy14081727

Editorial: Plant natural resins: from formation mechanism to ecological significance

Xupo Ding, Jinhui Chen and Petr Maděra

Front. Plant Sci., 2024, 15
DOI: 10.3389/fpls.2024.1412805

Genome-wide investigation of Cytochrome P450 superfamily of Aquilaria agallocha: Association with terpenoids and phenylpropanoids biosynthesis

Ankur Das, Khaleda Begum, Suraiya Akhtar, Raja Ahmed, Phatik Tamuli, Ram Kulkarni and Sofia Banu

International Journal of Biological Macromolecules, 2023, 234, 123758
DOI: 10.1016/j.ijbiomac.2023.123758

Analysis of the quality and characteristic chemical components of agarwood based on the drilling method for Qi-Nan agarwood

Deqiang Man, Yunlin Fu, Yingjian Li and Mengji Qiao

Industrial Crops and Products, 2024, 222, 119841
DOI: 10.1016/j.indcrop.2024.119841

In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease 

Phaniendra Alugoju, Vishwambar Vishnu Bhandare, Vishal S. Patil, Krishna Swamy V. K. D, Prem Kumar Borugadda and Tewin Tencomnao

F1000Res, 2024, 12, 230
DOI: 10.12688/f1000research.130618.2

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood

Xiao-Hui Wang, Bo-Wen Gao, Yu Nakashima, Takahiro Mori, Zhong-Xiu Zhang, Takeshi Kodama, Yuan-E Lee, Ze-Kun Zhang, Chin-Piow Wong, Qian-Qian Liu, Bo-Wen Qi, Juan Wang, Jun Li, Xiao Liu, Ikuro Abe, Hiroyuki Morita, Peng-Fei Tu and She-Po Shi

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-27971-z

Morphological, physiological, biochemical and molecular analyses reveal wounding-induced agarwood formation mechanism in two types of Aquilaria sinensis (Lour.) Spreng

Peng Zhang, Xiaofei Li, Zhiyi Cui and Daping Xu

Industrial Crops and Products, 2022, 178, 114603
DOI: 10.1016/j.indcrop.2022.114603

Agarwood Pill Enhances Immune Function in Cyclophosphamide-induced Immunosuppressed Mice

Seon Yeong Ji, Hyesook Lee, Hyun Hwangbo, Min Yeong Kim, Da Hye Kim, Beom Su Park, Young Tae Koo, Jin Soo Kim, Ki Won Lee, Jong Cheul Ko, Gi-Young Kim, EunJin Bang and Yung Hyun Choi

Biotechnol Bioproc E, 2023, 28, 63
DOI: 10.1007/s12257-022-0345-9

Agarwood as a potential therapeutic for Alzheimer's disease: Mechanistic insights and target identification

Ya-nan Ma, Xiqi Hu, Kenji Karako, Peipei Song, Wei Tang and Ying Xia

DD&T, 2024, 18, 375
DOI: 10.5582/ddt.2024.01085

Pivotal enzyme that involved in the biosynthesis of agarwood fragrances leading to development of artificial agarwood

Hiroyuki MORITA and She-Po SHI

Journal of Japan Association on Odor Environment, 2022, 53, 242
DOI: 10.2171/jao.53.242