Structure-based virtual screening of unbiased and RNA-focused libraries to identify new ligands for the HCV IRES model system

Elisabeth Kallert, Laura Almena Rodriguez, Jan-Åke Husmann, Kathrin Blatt and Christian Kersten

RSC Med. Chem., 2024, 15, 1527
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NMR 1H,19F-based screening of the four stem-looped structure 5_SL1–SL4 located in the 5′-untranslated region of SARS-CoV 2 RNA

Daniel Hymon, Jason Martins, Christian Richter, Sridhar Sreeramulu, Anna Wacker, Jan Ferner, Neeraj N. Patwardhan, Amanda E. Hargrove and Harald Schwalbe

RSC Med. Chem., 2024, 15, 165
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Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry

Aline Umuhire Juru, Zhengguo Cai, Adina Jan and Amanda E. Hargrove

Chem. Commun., 2020, 56, 3555
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Small molecule–RNA targeting: starting with the fundamentals

Amanda E. Hargrove

Chem. Commun., 2020, 56, 14744
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Forced intercalation-induced light-up peptides as fluorogenic indicators for the HIV-1 TAR RNA-ligand assay

En Ting Tabitha Lee, Yusuke Sato, Akunna F. Ujuagu and Seiichi Nishizawa

Analyst, 2024, 149, 4179
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Frameworks for targeting RNA with small molecules

Aline Umuhire Juru and Amanda E. Hargrove

Journal of Biological Chemistry, 2021, 296, 100191
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Recent applications of artificial intelligence in RNA-targeted small molecule drug discovery

Ella Czarina Morishita and Shingo Nakamura

Expert Opinion on Drug Discovery, 2024, 19, 415
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Small Molecules Targeting Viral RNA

Gregory Mathez and Valeria Cagno

IJMS, 2023, 24, 13500
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Reliable method for predicting the binding affinity of RNA-small molecule interactions using machine learning

Sowmya R Krishnan, Arijit Roy and M Michael Gromiha

Briefings in Bioinformatics, 2024, 25
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Quantitative Structure–Activity Relationship (QSAR) Study Predicts Small-Molecule Binding to RNA Structure

Zhengguo Cai, Martina Zafferani, Olanrewaju M. Akande and Amanda E. Hargrove

J. Med. Chem., 2022, 65, 7262
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IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex

Jesse Davila-Calderon, Neeraj N. Patwardhan, Liang-Yuan Chiu, Andrew Sugarman, Zhengguo Cai, Srinivasa R. Penutmutchu, Mei-Ling Li, Gary Brewer, Amanda E. Hargrove and Blanton S. Tolbert

Nat Commun, 2020, 11
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Versatile Target-Guided Screen for Discovering Bidirectional Transcription Inhibitors of a Trinucleotide Repeat Disease

Lauren D. Hagler, Sarah B. Krueger, Long M. Luu, Amie N. Lanzendorf, Niya L. Mitchell, J. Ignacio Vergara, L. Daniel Curet and Steven C. Zimmerman

ACS Med. Chem. Lett., 2021, 12, 935
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Structural and computational studies of HIV-1 RNA

Lev Levintov and Harish Vashisth

RNA Biology, 2024, 21, 167
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Design of deep-red emissive forced intercalation-induced light-up peptide as an indicator for the HIV-1 TAR RNA-ligand assay: integration of benzo[c,d]indole-quinoline (BIQ) cyanine dye into Tat peptide

Akunna Francess Ujuagu, Yusuke Sato, En Ting Tabitha Lee and Seiichi Nishizawa

ANAL. SCI., 2024, 40, 2089
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Ligand Recognition in Viral RNA Necessitates Rare Conformational Transitions

Lev Levintov and Harish Vashisth

J. Phys. Chem. Lett., 2020, 11, 5426
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R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures

Anita Donlic, Emily G. Swanson, Liang-Yuan Chiu, Sarah L. Wicks, Aline Umuhire Juru, Zhengguo Cai, Kamillah Kassam, Chris Laudeman, Bilva G. Sanaba, Andrew Sugarman, Eunseong Han, Blanton S. Tolbert and Amanda E. Hargrove

ACS Chem. Biol., 2022, 17, 1556
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Recognizing the power of machine learning and other computational methods to accelerate progress in small molecule targeting of RNA

Greta Bagnolini, TinTin B. Luu and Amanda E. Hargrove

RNA, 2023, 29, 473
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Designing small molecules targeting a cryptic RNA binding site through base displacement

Lukasz T. Olenginski, Aleksandra J. Wierzba, Shawn P. Laursen and Robert T. Batey

Nat Chem Biol, 2025
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Noncoding RNAs: biology and applications—a Keystone Symposia report

Jennifer Cable, Edith Heard, Tetsuro Hirose, Kannanganattu V. Prasanth, Ling‐Ling Chen, Jonathan E. Henninger, Sofia A. Quinodoz, David L. Spector, Sarah D. Diermeier, Allison M. Porman, Dhiraj Kumar, Mark W. Feinberg, Xiaohua Shen, Juan Pablo Unfried, Rory Johnson, Chun‐Kan Chen, Jeremy E. Wilusz, Adelheid Lempradl, Sean E. McGeary, Lamia Wahba, Anna Marie Pyle, Amanda E. Hargrove, Matthew D. Simon, Marco Marcia, Róża K. Przanowska, Howard Y. Chang, Samie R. Jaffrey, Lydia M. Contreras, Qi Chen, Junchao Shi, Joshua T. Mendell, Lin He, Erwei Song, John L. Rinn, Mukesh Kumar Lalwani, Murat Can Kalem, Edward B. Chuong, Lynne E. Maquat and Xuhang Liu

Annals of the New York Academy of Sciences, 2021, 1506, 118
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Recognition of Factors of Postoperative Complications of Knee Osteoarthritis Patients and Comprehensive Nursing Intervention

Ying Dong, Pei Zhang, Lidan Fan and Osamah Ibrahim Khalaf

Computational and Mathematical Methods in Medicine, 2021, 2021, 1
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