Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet

Juan Li, Jing Deng, Xuan Deng, Lianlian Liu and Xingfu Zha

Insects, 2023, 14, 347
DOI: 10.3390/insects14040347

Effects of Microbial Transfer during Food-Gut-Feces Circulation on the Health of Bombyx mori

Lijun Qin, Junpeng Qi, Guanwang Shen, Daoyuan Qin, Jinxin Wu, Yuwei Song, Yang Cao, Ping Zhao, Qingyou Xia, Chengshu Wang and Guanhong Wang

Microbiol Spectr, 2022, 10
DOI: 10.1128/spectrum.02357-22

Prolonging mulberry leaf longevity with silver-doped copper oxide nanoparticles: a postharvest approach

Dipayan Das, Payel Paul and Palash Mandal

Discov. Plants, 2025, 2
DOI: 10.1007/s44372-025-00130-6

Study of gut bacterial diversity of Bombyx mandarina and Bombyx mori through 16S rRNA gene sequencing

Dhiraj Kumar, Zhenli Sun, Guangli Cao, Renyu Xue, Xiaolong Hu and Chengliang Gong

Journal of Asia-Pacific Entomology, 2019, 22, 522
DOI: 10.1016/j.aspen.2019.03.005

Pediococcus pentosaceus ZZ61 enhances growth performance and pathogenic resistance of silkworm Bombyx mori by regulating gut microbiota and metabolites

Zhu Zeng, Xiaoling Tong, Yi Yang, Yuli Zhang, Shuwen Deng, Guizheng Zhang and Fangyin Dai

Bioresource Technology, 2024, 402, 130821
DOI: 10.1016/j.biortech.2024.130821

Dynamic Alterations of the Intestinal Microbiota of Fifth-Instar Silkworms (Bombyx mori) Fed an Artificial Diet or Mulberry Leaves

Chuanjie Chen, Meng Li, Feng Li, Xiaoyan Liang, Haiyang Zhang, Yinyu Gu and Guang Guo

Insects, 2024, 15, 970
DOI: 10.3390/insects15120970

The physiological and toxicological effects of antibiotics on an interspecies insect model

Guannan Li, Xuejuan Xia, Shan Zhao, Min Shi, Fengdan Liu and Yong Zhu

Chemosphere, 2020, 248, 126019
DOI: 10.1016/j.chemosphere.2020.126019

Effects of Agro-Industrial Byproduct-Based Diets on the Growth Performance, Digestibility, Nutritional and Microbiota Composition of Mealworm (Tenebrio molitor L.)

Ana Montalbán, Cristian Sánchez, Fuensanta Hernández, Achille Schiavone, Josefa Madrid and Silvia Martínez-Miró

Insects, 2022, 13, 323
DOI: 10.3390/insects13040323

Characterization of tasar silkworm Antheraea mylitta drury (Saturniidae: Lepidoptera) midgut bacterial symbionts through metagenomic analysis

Mohammed Muzeruddin Baig, Gajendrapal Singh, Devdoss Immanual Gilwax Prabhu, Manjappa, Alok Sahay and Sathyanarayana Kutala

Int J Trop Insect Sci, 2023, 43, 999
DOI: 10.1007/s42690-023-01006-6

From phyllosphere to insect cuticles: silkworms gather antifungal bacteria from mulberry leaves to battle fungal parasite attacks

Pengfei Zhao, Song Hong, Yuekun Li, Haimin Chen, Hanchun Gao and Chengshu Wang

Microbiome, 2024, 12
DOI: 10.1186/s40168-024-01764-6

The Ability to Digest Cellulose Can Significantly Improve the Growth and Development of Silkworms

Jinxin Wu, Yungui Zhang, Han Chen, Qingyou Xia, Ping Zhao, Ying Lin and Guanwang Shen

Insects, 2024, 15, 997
DOI: 10.3390/insects15120997

Multi-tissue metabolomic profiling reveals potential mechanisms of cocoon yield in silkworms (Bombyx mori) fed formula feed versus mulberry leaves

Xuehui Wu, Xuedong Chen, Aihong Ye, Jinru Cao, Ruimin He, Meiliang Pan, Feng Jin, Huanyan Ma and Wenlin Zhou

Front. Mol. Biosci., 2022, 9
DOI: 10.3389/fmolb.2022.977047

Purified fibers in chemically defined synthetic diets destabilize the gut microbiome of an omnivorous insect model

Rachel Louise Dockman and Elizabeth A. Ottesen

Front. Microbiomes, 2024, 3
DOI: 10.3389/frmbi.2024.1477521

Disentangling the Role of Microbiota: A Special Emphasis on Lepidoptera

S. R. Subhasree, N. Balakrishnan, R. Anandham, M. Murugan, T. Srinivasan, R. Raghu and S. K. Manoranjitham

Curr Microbiol, 2026, 83
DOI: 10.1007/s00284-026-04810-8

A comparative study of the effects of all-instar mulberry leaf and artificial diet on structure and properties of silkworm silk

Jie Huang, Yu Wang, Yuhang Ling, Doston Samandarov, Yubin Dong and Yaqin Fu

Materials & Design, 2026, 264, 115794
DOI: 10.1016/j.matdes.2026.115794

Impact of Artificial Diet Versus Mulberry Leaves on Silkworm Growth, Nutrient Composition, and Gut Microbiota

Jong Woo Park, Jeong Sun Park, Pu Reun Kook, Yeong Hee Cho, Seul Ki Park, Ji Hae Lee, Sang Kuk Kang, Seong‐Wan Kim and Seong‐Ryul Kim

Arch Insect Biochem Physiol, 2025, 120
DOI: 10.1002/arch.70113

A Silkworm Infection Model for In Vivo Study of Glycopeptide Antibiotics

Aurora Montali, Francesca Berini, Maurizio Francesco Brivio, Maristella Mastore, Alessio Saviane, Silvia Cappellozza, Flavia Marinelli and Gianluca Tettamanti

Antibiotics, 2020, 9, 300
DOI: 10.3390/antibiotics9060300

Effects of baculovirus infection on intestinal microflora of BmNPV resistant and susceptible strain silkworm

Shi-Huo Liu, Ying Zhang, Zhe-Xiao Guo, Sadaf Ayaz, Yan-Xiang Wang, Zhi-Hao Huang, Hui-Hua Cao, Jia-Ping Xu and Scott Geib

Journal of Economic Entomology, 2024, 117, 1141
DOI: 10.1093/jee/toae088

Combined analysis of silk synthesis and hemolymph amino acid metabolism reveal key roles for glycine in increasing silkworm silk yields

Xuedong Chen, Aihong Ye, Xuehui Wu, Zhigang Qu, Shiqing Xu, Yanghu Sima, Yujun Wang, Ruimin He, Fen Jin, Pengfei Zhan, Jinru Cao and Wenlin Zhou

International Journal of Biological Macromolecules, 2022, 209, 1760
DOI: 10.1016/j.ijbiomac.2022.04.143

Comparative Fecal Metabolomes of Silkworms Being Fed Mulberry Leaf and Artificial Diet

DaoYuan Qin, GenHong Wang, ZhaoMing Dong, QingYou Xia and Ping Zhao

Insects, 2020, 11, 851
DOI: 10.3390/insects11120851

Dietary calcium carbonate supplementation prolonged larval development by increasing the moltinism of the lepidopteran model Bombyx mori

Xiaoning Sun, Guang Wang, Zhitian Xiao, Ruihong Zhu, Yumei Tan, Shiqiang Liu, Zhonghua Pan, Shiqing Xu and Yanghu Sima

Food Bioscience, 2025, 64, 105905
DOI: 10.1016/j.fbio.2025.105905

Comparative Analysis of the Gut Bacterial Community in Laboratory-Reared and Seasonally Field-Released Larvae of the Antheraea pernyi

Peng Hou, Li Liu, Ding Yang, Chuntian Zhang and Jianfeng Wang

Insects, 2026, 17, 79
DOI: 10.3390/insects17010079

Analysis of gut microbiota of ladybug beetle (Harmonia axyridis) after feeding on different artificial diets

Bing-Hua Xie, Lei Chao, Si-Jing Wan, Hui-Ru Si, Wei-Dong Yu, Zhen Huang, Shi-Gui Wang, Nicolas Desneux, Bin Tang and Si-Si Sun

BMC Microbiol, 2024, 24
DOI: 10.1186/s12866-023-03155-7

Sugarcane Wax Metabolites and Their Toxicity to Silkworms

Li Ma, Mingzheng Duan, Ziwei He, Yu Zhang, Yiting Chen, Bo Li, Muhammad Junaid Rao, Lihua Hu and Lingqiang Wang

Life, 2023, 13, 286
DOI: 10.3390/life13020286

İpekböceği (Bombyx mori L.) Yetiştiriciliğinde Yapay Yem Karışımlarının Kullanımı

Fehmi GÜREL

EJOSAT, 2023
DOI: 10.31590/ejosat.1274467

Beneficial efficacy and mode of action of probiotic Bacillus subtilis SWL−19 on the silkworm (Bombyx mori L.)

Guannan Li, Yi Xiao, Jia Leng, Qinian Lou and Tianfu Zhao

Symbiosis, 2024, 93, 17
DOI: 10.1007/s13199-024-00986-4

A simple artificial diet available for research of silkworm disease models

Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto and Kazuhisa Sekimizu

DD&T, 2020, 14, 177
DOI: 10.5582/ddt.2020.03061

Gut microbiota assemblages of generalist predators are driven by local- and landscape-scale factors

Hafiz Sohaib Ahmed Saqib, Linyang Sun, Gabor Pozsgai, Pingping Liang, Mohsan Ullah Goraya, Komivi Senyo Akutse, Minsheng You, Geoff M. Gurr and Shijun You

Front. Microbiol., 2023, 14
DOI: 10.3389/fmicb.2023.1172184

Gut Microbiota Analysis in Silkworms (Bombyx mori) Provides Insights into Identifying Key Bacterials for Inclusion in Artificial Diet Formulations

Lei Xin, Yazhen Chen, Wantao Rong, Yingcan Qin, Xiaodong Li and Delong Guan

Animals, 2024, 14, 1261
DOI: 10.3390/ani14091261

Microbial community formation during dietary exposure to Fe3O4-urease nanoconjugates in silkworm (Bombyx mori): Principal fungi groups facilitate functional flux

Richard Ansah Herman, Zhan-Peng Zhang, Marriam Khurshid, Ellen Ayepa, Cheng-Hai Yan, Jacob Paarechuga Anankware and Jun Wang

International Journal of Biological Macromolecules, 2025, 306, 141367
DOI: 10.1016/j.ijbiomac.2025.141367

Effects of artificial diet breeding on intestinal microbial populations at the young stage of silkworm (Bombyx mori)

Qilong Shu, Yuanfei Wang, Haoyi Gu, Qingyu Zhu, Wei Liu, Yan Dai, Fanchi Li and Bing Li

Arch Insect Biochem Physiol, 2023, 113
DOI: 10.1002/arch.22019

Comparative analysis of gut bacteria of silkworm Bombyx mori L. on exposure to temperature through 16S rRNA high throughput metagenomic sequencing

K.I. Shahila Ismail, C.V. Sreeranjit Kumar, U. Aneesha, P.S. Syama and K.P. Sajini

Journal of Invertebrate Pathology, 2023, 201, 107992
DOI: 10.1016/j.jip.2023.107992

Bacillus symbiont drives alterations in intestinal microbiota and circulating metabolites of lepidopteran host

Guannan Li, Xi Zheng, Yong Zhu, Yaohang Long and Xuejuan Xia

Environmental Microbiology, 2022, 24, 4049
DOI: 10.1111/1462-2920.15934

Different Gut Microbiomes of Developmental Stages of Field-Collected Native and Invasive Western Bean Cutworm, Striacosta albicosta, in Western Nebraska

Paul A. Ayayee, Austin Currie and Julie A. Peterson

Microorganisms, 2022, 10, 1828
DOI: 10.3390/microorganisms10091828

Influence of Tobiko-Mixed Artificial Diet on Textile Properties of Bombyx mori Silkworm Cocoons

Masaki Yamamoto, Junichi Machida, Masato Shinohara, Akira Igarashi and Yutaka Kawahara

Journal of Natural Fibers, 2022, 19, 5851
DOI: 10.1080/15440478.2021.1901829

The Influence of Gut Microbiota on the Fecundity of Henosepilachna vigintioctopunctata (Coleoptera: Coccinellidae)

Hanwen Li, Changwei Zhao, Yang Yang, Zhixiong Zhou, Jingwei Qi, Chuanren Li and Julie Urban

Journal of Insect Science, 2021, 21
DOI: 10.1093/jisesa/ieab061

Ecological and functional dynamics of gut microbiota in the model insect, silkworm Bombyx mori

Abrar Muhammad, Chao Sun and Yongqi Shao

World J Microbiol Biotechnol, 2026, 42
DOI: 10.1007/s11274-026-04784-6

The silkworm (Bombyx mori) gut microbiota is involved in metabolic detoxification by glucosylation of plant toxins

Shuangzhi Yuan, Yong Sun, Wenqiang Chang, Jiaozhen Zhang, Jifa Sang, Jiachun Zhao, Minghui Song, Yanan Qiao, Chunyang Zhang, Mingzhu Zhu, Yajie Tang and Hongxiang Lou

Commun Biol, 2023, 6
DOI: 10.1038/s42003-023-05150-0

Differential Profiles of Gut Microbiota and Metabolites Associated with Host Shift of Plutella xylostella

Fei-Ying Yang, Hafiz Sohaib Ahmed Saqib, Jun-Hui Chen, Qian-Qian Ruan, Liette Vasseur, Wei-Yi He and Min-Sheng You

IJMS, 2020, 21, 6283
DOI: 10.3390/ijms21176283

Evaluation of tolerance to λ-cyhalothrin and response of detoxification enzymes in silkworms reared on artificial diet

Dandan Bian, Yuying Ren, Wentao Ye, Minli Dai, Fanchi Li, Jing Wei, Haina Sun and Bing Li

Ecotoxicology and Environmental Safety, 2022, 232, 113232
DOI: 10.1016/j.ecoenv.2022.113232

Genomic Analysis Reveals Novel Genes and Adaptive Mechanisms for Artificial Diet Utilization in the Silkworm Strain Guican No.5

Lei Xin, Delong Guan, Nan Wei, Xiaoyan Zhang, Weian Deng, Xiaodong Li and Jing Song

Insects, 2024, 15, 1010
DOI: 10.3390/insects15121010

Lactic Acid Bacteria from Bombyx mori Frass: Probiotic Properties and Antagonistic Activities

Siripuk Suraporn, Sopa Cansee, Sebastian Hupfauf and Thomas Klammsteiner

Agriculture, 2024, 14, 924
DOI: 10.3390/agriculture14060924

Probiotic Bacillus subtilis enhances silkworm (Bombyx mori) growth performance and silk production via modulating gut microbiota and amino acid metabolism

Chunjiu Ren, Yingchen Meng, Yangyang Liu, Yi Wang, Huizhen Wang, Yating Liu, Changjun Liu, Xin Fan and Shengxiang Zhang

anim microbiome, 2025, 7
DOI: 10.1186/s42523-025-00473-1

Silkworm (Bombyx mori) gut bacteria respond positively to exposure of magnetic Fe3O4@urease-doped nanoconjugates: potential reconstruction for nutritional efficiency

Richard Ansah Herman, Marriam Khurshid, Zhan-Peng Zhang, Cheng-Hai Yan, Ellen Ayepa, Yi-Jiang-Cheng Li, Shuai You, Sheng Sheng and Jun Wang

anim microbiome, 2025, 8
DOI: 10.1186/s42523-025-00500-1

Characterization of Spodoptera litura Gut Bacteria and Their Role in Feeding and Growth of the Host

Xiaofeng Xia, Bomiao Lan, Xinping Tao, Junhan Lin and Minsheng You

Front. Microbiol., 2020, 11
DOI: 10.3389/fmicb.2020.01492

Effects of Habitual Dietary Change on the Gut Microbiota and Health of Silkworms

Guang Wang, Xueyan Ding, Jiameng Yang, Lu Ma, Xiaoning Sun, Ruihong Zhu, Riming Lu, Zhitian Xiao, Zhiyi Xing, Jingbin Liu, Zhonghua Pan, Shiqing Xu and Yanghu Sima

IJMS, 2024, 25, 1722
DOI: 10.3390/ijms25031722

Metabonomic analysis of the haemolymph reveals the dual effects of dietary selenium supplementations on growth of silkwormBombyx mori

R. Zhang, L.L. Peng, H.T. Zhu, L. Jiang, K. Thakur, S.M. Tang, F. Hu and Z.J. Wei

JIFF, 2023, 9, 475
DOI: 10.3920/JIFF2022.0092

Bugs in Bugs: The Role of Probiotics and Prebiotics in Maintenance of Health in Mass-Reared Insects

Carlotta Savio, Loretta Mugo-Kamiri and Jennifer K. Upfold

Insects, 2022, 13, 376
DOI: 10.3390/insects13040376

Effects of different rearing methods on cocoon silk strength in silkworm Bombyx mori (Lepidoptera: Bombycidae)

Shengxiang Zhang, Ran Liu, Fengjie Lan, Yi Wang, Huizhen Wang, Yangyang Liu, Chunjiu Ren, Huiju Gao and Yan-Qun Liu

Journal of Economic Entomology, 2024, 117, 2292
DOI: 10.1093/jee/toae242

Bombyx mori bidensovirus infection alters the intestinal microflora of fifth instar silkworm (Bombyx mori) larvae

Dhiraj Kumar, Zhenli Sun, Guangli Cao, Renyu Xue, Xiaolong Hu and Chengliang Gong

Journal of Invertebrate Pathology, 2019, 163, 48
DOI: 10.1016/j.jip.2019.03.004

Microbiota-responsive BmMBF2-11 limits dysbiosis and promotes intestinal immune homeostasis in the silkworm

Qingxiu He, Rui Yang, Huawei Liu, Huanan Zhu, Yu Zhang, Hao Chen, Qingsong Liu, Guangcheng Huang, Qingyou Xia and Ping Zhao

Insect Biochemistry and Molecular Biology, 2026, 190, 104516
DOI: 10.1016/j.ibmb.2026.104516