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Yujie Tan, Jing Feng, Yu Xiao and Chongyun Bao

J. Mater. Chem. B, 2022, 10, 4840
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Nanomaterials: innovative approaches for addressing key objectives in periodontitis treatment

Ruijianghan Shi, Yujie Zhu, Weitong Lu, Ruohan Zhai, Mi Zhou, Sirong Shi and Yang Chen

RSC Adv., 2024, 14, 27904
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Sustained release of chlorogenic acid-loaded nanomicelles alleviates bone loss in mouse periodontitis

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Buteinylated-hafnium oxide bionanoparticles for electrochemical sensing of wogonin

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Nanoscale, 2023, 15, 18727
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The implication of the PD-1/PD-L1 checkpoint in chronic periodontitis suggests novel therapeutic opportunities with natural products

Christian Bailly

Japanese Dental Science Review, 2020, 56, 90
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Baicalein Alleviates Arsenic-induced Oxidative Stress through Activation of the Keap1/Nrf2 Signalling Pathway in Normal Human Liver Cells

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Local Delivery and Controlled Release Drugs Systems: A New Approach for the Clinical Treatment of Periodontitis Therapy

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Liposome-Encapsulated Baicalein Suppressed Lipogenesis and Extracellular Matrix Formation in Hs68 Human Dermal Fibroblasts

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Metronidazole-Treated Porphyromonas gingivalis Persisters Invade Human Gingival Epithelial Cells and Perturb Innate Responses

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ROS-responsive hollow mesoporous silica nanoparticles loaded with Glabridin for anti-pigmentation properties

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Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health

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Some Nanocarrier’s Properties and Chemical Interaction Mechanisms with Flavones

Cecilia Espíndola

Molecules, 2023, 28, 2864
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Molecular targets and therapeutic potential of baicalein: a review

Kavita Munjal, Yash Goel, Vinod Kumar Gauttam, Hitesh Chopra, Madhav Singla, Smriti, Saurabh Gupta and Rohit Sharma

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Baicalein Treatment Promotes Osteoblast Proliferation and Osteogenic Differentiation through Activation of Immediate Early Response 3

Sang-Im Lee

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Physicochemical and biological properties of dental materials and formulations with silica nanoparticles: A narrative review

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Dental Materials, 2024, 40, 1729
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A glutathione-responsive silica-based nanosystem capped with in-situ polymerized cell-penetrating poly(disulfide)s for precisely modulating immuno-inflammatory responses

Xuan Li, Chuan Wang, Leilei Wang, Regina Huang, Wai-Chung Li, Xinna Wang, Sarah Sze Wah Wong, Zongwei Cai, Ken Cham-Fai Leung and Lijian Jin

Journal of Colloid and Interface Science, 2022, 614, 322
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Enhanced topical permeability of natural flavonoid baicalein through nano liposomal gel: In vitro and in vivo investigation

Subhabrota Majumdar, Sanjay Dey, Debgopal Ganguly and Rana Mazumder

Journal of Drug Delivery Science and Technology, 2020, 57, 101666
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Anti-Ageing Protein β-Klotho Rejuvenates Diabetic Stem Cells for Improved Gene-Activated Scaffold Based Wound Healing

Meenakshi Suku, Ashang Luwang Laiva, Fergal J. O’Brien and Michael B. Keogh

JPM, 2020, 11, 4
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Protective role of flavonoid baicalin from Scutellaria baicalensis in periodontal disease pathogenesis: A literature review

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Pre-clinical evaluation of an innovative oral nano-formulation of baicalein for modulation of radiation responses

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International Journal of Pharmaceutics, 2021, 595, 120181
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The anti-inflammatory and autophagy-induced effects of baicalin in ankylosing spondylitis hip ligament fibroblasts

Ran Wu, Chen Wang, Xinzhe Feng, Wenjie Lu, Yibo Fei, Ling Xu, Fang Huang and Weidong Xu

Journal of Herbal Medicine, 2023, 42, 100780
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Natural products with anti-tumorigenesis potential targeting macrophage

Hao Liu, Manru Huang, Dandan Xin, Hong Wang, Haiyang Yu and Weiling Pu

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A baicalin-loaded coaxial nanofiber scaffold regulated inflammation and osteoclast differentiation for vascularized bone regeneration

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Bioactive Materials, 2022, 8, 559
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A potent protective effect of baicalein on liver injury by regulating mitochondria-related apoptosis

Zhongjie Yu, Qi Li, Yin Wang and Peifeng Li

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One-Pot Preparation of Cetylpyridinium Chloride-Containing Nanoparticles for Biofilm Eradication

Alexander Brezhnev, Fung-Kit Tang, Chak-Shing Kwan, Mohammed S. Basabrain, James Kit Hon Tsoi, Jukka P. Matinlinna, Prasanna Neelakantan and Ken Cham-Fai Leung

ACS Appl. Bio Mater., 2023, 6, 1221
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Preparation and characterization of antioxidant packaging by chitosan, D-α-tocopheryl polyethylene glycol 1000 succinate and baicalein

Huimin Yong, Fengyu Bi, Jing Liu, Yan Qin, Ruyu Bai and Jun Liu

International Journal of Biological Macromolecules, 2020, 153, 836
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Baicalein—A review on its molecular mechanism against breast cancer and delivery strategies

Shraddha Srivastava, Jose Mathew and Avinash chandra Pandey

Med Chem Res, 2023, 32, 643
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New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration

Jiaxin Li, Yuxiao Wang, Maomao Tang, Chengdong Zhang, Yachen Fei, Meng Li, Mengjie Li, Shuangying Gui and Jian Guo

J Nanobiotechnol, 2024, 22
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Baicalein inhibits inflammatory response and promotes osteogenic activity in periodontal ligament cells challenged with lipopolysaccharides

Manman Ren, Ya Zhao, Zhiqi He, Jian Lin, Chuchu Xu, Fen Liu, Rongdang Hu, Hui Deng and Yi Wang

BMC Complement Med Ther, 2021, 21
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Nanomedicine and Periodontal Regenerative Treatment

Olivier Huck, Céline Stutz, Pierre-Yves Gegout, Hayriye Özçelik, Nadia Benkirane-Jessel, Catherine Petit and Fareeha Batool

Dental Clinics of North America, 2022, 66, 131
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Inflammation Affects the Osteogenic Differentiation of Aged Periodontal Ligament Cells via NF‐κB/FOXO3a/c‐JUN Signalling

Luying Zhu, Zhongyuan Tang, Renjie Hu, Yaxin Li, Xuan Li, Min Gu and Yanqi Yang

J of Periodontal Research, 2025
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Baicalein: A metabolite with promising antineoplastic activity

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Life Sciences, 2020, 259, 118183
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How Will Nanomedicine Revolutionize Future Dentistry and Periodontal Therapy?

Emira D’Amico, Gitana Maria Aceto, Morena Petrini, Chiara Cinquini, Simonetta D’Ercole, Giovanna Iezzi and Tania Vanessa Pierfelice

IJMS, 2025, 26, 592
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Hierarchy of hybrid materials. Part-II: The place of organics-on-inorganics in it, their composition and applications

Junnan Song, Anna S. Vikulina, Bogdan V. Parakhonskiy and Andre G. Skirtach

Front. Chem., 2023, 11
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Therapeutic Efficacy of Baicalein Green Biomolecule in Methicillin-Resistant Staphylococcus aureus Murine Mastitis Model

Srishti Soni, Reena Mukherjee, Ujjwal Kumar De, Deeksha Bharti, Mamta Singh, Babul Rudra Paul, Varun Kumar Sarkar, Khan Sharun, N. Barkathullah and M. Saminathan

J. Pure Appl. Microbiol., 2024, 18, 1546
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Eradication of Porphyromonas gingivalis Persisters Through Colloidal Bismuth Subcitrate Synergistically Combined With Metronidazole

Chuan Wang, Xuan Li, Tianfan Cheng, Hongzhe Sun and Lijian Jin

Front. Microbiol., 2021, 12
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Baicalein Inhibits Streptococcus mutans Biofilms and Dental Caries-Related Virulence Phenotypes

Aparna Vijayakumar, Hema Bhagavathi Sarveswari, Sahana Vasudevan, Karthi Shanmugam, Adline Princy Solomon and Prasanna Neelakantan

Antibiotics, 2021, 10, 215
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Flavonoids exert multiple periodontic benefits including anti-inflammatory, periodontal ligament-supporting, and alveolar bone-preserving effects

Berenice Fernández-Rojas and Gloria Gutiérrez-Venegas

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Baicalein ameliorates SEB-induced acute respiratory distress syndrome in a microbiota-dependent manner

Tingting Hu, Ying Zhu, Xiang Zhou, Miaoyun Ye, Xuecheng Wang, Chen Lu and Yaqi Wang

Phytomedicine, 2024, 135, 156049
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7,8-Dihydroxyflavone-Functionalized Gold Nanoparticles Target The Arginase Enzyme of Leishmania Donovani

Pragya Prasanna, Prakash Kumar, Saptarshi Mandal, Tanvi Payal, Saurabh Kumar, Sk Ugir Hossain, Prolay Das, V Ravichandiran and Debabrata Mandal

Nanomedicine (Lond.), 2021, 16, 1887
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Engineering baicalin-encapsulated PCL-PEG nanoparticles for enhanced anti-colorectal cancer applications

Huayi Feng, Yinzi Yue, Lianlin Su, Shuai Yan and Zhengjun Li

Arab J Chem, 2025, 18, 4412025
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Effects of Nanomaterials on Synthesis and Degradation of the Extracellular Matrix

Zhiyan Zhou, Yanli Zhang, Yuting Zeng, Dehong Yang, Jiayao Mo, Ziting Zheng, Yuxin Zhang, Ping Xiao, Xincen Zhong and Wenjuan Yan

ACS Nano, 2024, 18, 7688
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Recent advances in nanomaterials for integrated phototherapy and immunotherapy

Zhuqing Sun, Nannan Wang, Yelin Wu, Shihui Wen and Dayong Jin

Coordination Chemistry Reviews, 2025, 535, 216608
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Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants

Aurelia Magdalena Pisoschi, Florin Iordache, Loredana Stanca, Carmen Cimpeanu, Florin Furnaris, Ovidiu Ionut Geicu, Liviu Bilteanu and Andreea Iren Serban

European Journal of Medicinal Chemistry, 2024, 265, 116075
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Infiltration and Profiles of Mesoporous Silica Nanoparticles in Dentinal Tubules

Xin Li, Xuan Li, Shuai Wang, Ken Cham-Fai Leung, Chengfei Zhang and Lijian Jin

ACS Biomater. Sci. Eng., 2018, 4, 1428
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An updated review of Chinese skullcap (Scutellaria baicalensis): Emphasis on phytochemical constituents and pharmacological attributes

Dilip Kumar Chanchal, Kuldeep Singh, Bharat Bhushan, Jitendra Singh Chaudhary, Shivendra Kumar, Ajit Kumar Varma, Neha Agnihotri and Akash Garg

Pharmacological Research - Modern Chinese Medicine, 2023, 9, 100326
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Revolutionizing oral care: Reactive oxygen species (ROS)-Regulating biomaterials for combating infection and inflammation

Wei Zhao, Yu Zhang, Jing Chen and Danrong Hu

Redox Biology, 2025, 79, 103451
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Photothermal therapy with regulated Nrf2/NF-κB signaling pathway for treating bacteria-induced periodontitis

Yujuan Tian, Ying Li, Jialin Liu, Yi Lin, Jian Jiao, Bo Chen, Wanmeng Wang, Shuilin Wu and Changyi Li

Bioactive Materials, 2022, 9, 428
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Metal-organic framework-based nanoplatform enhance fibroblast activity to treat periodontitis

Jian JIAO, Yujuan TIAN, Ying LI, Yunkai LIANG, Shu DENG, Wanmeng WANG, Yuwei WANG, Yi LIN, Yuan TIAN and Changyi LI

Dent. Mater. J., 2023, 42, 19
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The therapeutic role of baicalein in combating experimental periodontitis with diabetes via Nrf2 antioxidant signaling pathway

Chunhui Zhu, Ying Zhao, Xiaoyan Wu, Cui Qiang, Jin Liu, Jianfeng Shi, Jianzhong Gou, Dandan Pei and Ang Li

J of Periodontal Research, 2020, 55, 381
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Local drug delivery systems as therapeutic strategies against periodontitis: A systematic review

Ying Wei, Yaxin Deng, Shuting Ma, Meixin Ran, Yannan Jia, Jia Meng, Fei Han, Jingxin Gou, Tian Yin, Haibing He, Yanjiao Wang, Yu Zhang and Xing Tang

Journal of Controlled Release, 2021, 333, 269
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Enhancement of bioavailability and bioactivity of diet-derived flavonoids by application of nanotechnology: a review

Hui Teng, Yimei Zheng, Hui Cao, Qun Huang, Jianbo Xiao and Lei Chen

Critical Reviews in Food Science and Nutrition, 2023, 63, 378
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