Rh(iii)-catalyzed redox-neutral C–H alkenylation of benzamides with gem-difluorohomoallylic silyl ethers via β-H elimination

Xueli Cui, Jing Qu, Jianfeng Yi, Weiqiang Sun, Jinhui Hu, Suqin Guo, Jing-Wei Jin, Wen-Hua Chen, Wing-Leung Wong and Jia-Qiang Wu

Chem. Commun., 2023, 59, 3747
DOI: 10.1039/D3CC00529A

Csp3–H monofluoroalkenylation via stereoselective C–F bond cleavage

Ying Hu, Xingchen Liu, Zhouyang Ren, Binjing Hu and Jie Li

Chem. Commun., 2022, 58, 2734
DOI: 10.1039/D1CC06247F

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

Carlo Sambiagio, David Schönbauer, Remi Blieck, Toan Dao-Huy, Gerit Pototschnig, Patricia Schaaf, Thomas Wiesinger, Muhammad Farooq Zia, Joanna Wencel-Delord, Tatiana Besset, Bert U. W. Maes and Michael Schnürch

Chem. Soc. Rev., 2018, 47, 6603
DOI: 10.1039/C8CS00201K

Nickel-catalyzed defluorinative alkylation of C(sp2)–F bonds

Xue Tong, Si-Si Luo, Hua Shen, Shu Zhang, Tian Cao, Yi-Peng Luo, Long-Ling Huang, Xi-Tao Ma and Xiang-Wei Liu

Org. Chem. Front., 2021, 8, 4533
DOI: 10.1039/D1QO00549A

Synthesis of fluorinated allylic alcoholsviaphotoinduced decarboxylative cross-coupling of α-fluoroacrylic acids and alcohols

Xiao-Yu Lu, Meng-Ting Gao, Li-Juan Yu, Hong-Ye Pan, Xiang Zhang, Rui Huang, Kang Yang, Fu-Yi Shui, Yi-Wei Song and Gui-Xian Yang

Org. Chem. Front., 2023, 10, 1788
DOI: 10.1039/D3QO00068K

Rh-Catalyzed C–H bond alkylation of indoles with α,α-difluorovinyl tosylate via indolyl group migration

Lu Zhou, Chuan Zhu, Teck-Peng Loh and Chao Feng

Chem. Commun., 2018, 54, 5618
DOI: 10.1039/C8CC02183J

Rhodium(iii)-catalyzed C–H/C–F activation sequence: expedient and divergent synthesis of 2-benzylated indoles and 2,2′-bis(indolyl)methanes

Bing Shu, Shao-Yong Chen, Nan-Xiang Deng, Tao Zheng, Hui Xie, Xiao-Ling Xie, Jia-Qiang Wu, Hua Cao and Shang-Shi Zhang

Org. Chem. Front., 2021, 8, 4445
DOI: 10.1039/D1QO00462J

Copper-catalyzed enantioselective fluoroalkenylation of cyclic imino esters

Zhiwei Chen, Xiang Huang, Jian Liao and Min Wang

Org. Chem. Front., 2023, 10, 163
DOI: 10.1039/D2QO01141G

Photoinduced C–H monofluoroalkenylation with gem-difluoroalkenes through hydrogen atom transfer under batch and flow conditions

Chen-Lin Cao, Guang-Xu Zhang, Fei Xue and Hong-Ping Deng

Org. Chem. Front., 2022, 9, 959
DOI: 10.1039/D1QO01689J

Synthesis of α-CF3and α-CF2H aminesviathe aminofluorination of fluorinated alkenes

Ling Yang, Wen-Xin Fan, E. Lin, Dong-Hang Tan, Qingjiang Li and Honggen Wang

Chem. Commun., 2018, 54, 5907
DOI: 10.1039/C8CC03364A

Copper-catalyzed direct monofluoroalkenylation of C(sp3)–H bondsviadecarboxylation of α-fluoroacrylic acids

Xiao-Yu Lu, Xing-Ke Chen, Meng-Ting Gao, Xiao-Mei Sun, Run-Chuang Jiang, Jun-Chao Wang, Li-Juan Yu, Meng-Yuan Ge, Zheng-Huan Wei and Zi Liu

Org. Chem. Front., 2022, 9, 4712
DOI: 10.1039/D2QO00977C

Recent trends in catalytic sp3 C–H functionalization of heterocycles

Milanpreet Kaur and Jeffrey F. Van Humbeck

Org. Biomol. Chem., 2020, 18, 606
DOI: 10.1039/C9OB01559K

Rhodium(iii)-catalyzed unreactive C(sp3)–H alkenylation of N-alkyl-1H-pyrazoles with alkynes

Tongyu Li, Chang Liu, Shaonan Wu, Chen Chen and Bolin Zhu

Org. Biomol. Chem., 2019, 17, 7679
DOI: 10.1039/C9OB01531K

Rh(iii)-Catalyzed α-fluoroalkenylation of N-nitrosoanilines with 2,2-difluorovinyl tosylates via C–H bond activation

Miaomiao Tian, Xifa Yang, Bo Zhang, Bingxian Liu and Xingwei Li

Org. Chem. Front., 2018, 5, 3406
DOI: 10.1039/C8QO00947C

Transition metal-catalyzed C(sp2/sp3)–H α-fluoroalkenylation from gem-(bromo/di)fluoroalkenes to monofluoroalkenes: scope, mechanisms, and synthetic applications

Essam M. Eliwa, Ahmed H. Bedair and Jean-Pierre Djukic

Org. Biomol. Chem., 2024, 22, 6860
DOI: 10.1039/D4OB01044B

Recent advances in transition-metal catalyzed directed C–H functionalization with fluorinated building blocks

Haritha Sindhe, Bharatkumar Chaudhary, Neelanjan Chowdhury, Akshay Kamble, Vivek Kumar, Aishwarya Lad and Satyasheel Sharma

Org. Chem. Front., 2022, 9, 1742
DOI: 10.1039/D1QO01544C

Synthesis of 2-aminobenzofurans via base-mediated [3 + 2] annulation of N-phenoxy amides with gem-difluoroalkenes

Kaifeng Chen, Weijie Chen, Fangyuan Chen, Haiman Zhang, Huiying Xu, Zhi Zhou and Wei Yi

Org. Chem. Front., 2021, 8, 4452
DOI: 10.1039/D1QO00709B

Rhodium-catalyzed coupling of arenes and fluorinated α-diazo diketones: synthesis of chromones

Jiayi Yao, Lingheng Kong and Xingwei Li

Chem. Commun., 2020, 56, 13169
DOI: 10.1039/D0CC05664B

Rh(iii)-Catalyzed straightforward arylation of 8-methyl/formylquinolines using diazo compounds

Bidhan Ghosh and Rajarshi Samanta

Chem. Commun., 2019, 55, 6886
DOI: 10.1039/C9CC02391G

Recent advances in three-component difunctionalization ofgem-difluoroalkenes

Chi Liu, Hao Zeng, Chuanle Zhu and Huanfeng Jiang

Chem. Commun., 2020, 56, 10442
DOI: 10.1039/D0CC04318D

Photocatalytic C−F Bond Activation of Fluoroarenes, gem‐Difluoroalkenes and Trifluoromethylarenes

Wengang Xu, Qiao Zhang, Qi Shao, Congjian Xia and Mingbo Wu

Asian J Org Chem, 2021, 10, 2454
DOI: 10.1002/ajoc.202100426

Rh(III)‐Catalyzed Diverse C—H Functionalization of Iminopyridinium Ylides

Zhenzhen Dong, Pengfei Li, Xingwei Li and Bingxian Liu

Chin. J. Chem., 2021, 39, 2489
DOI: 10.1002/cjoc.202100203

Palladium-Catalyzed [4+1] Cycloaddition of 3,3-Difluoropent-4-en-2-ones with Amines: A Modular Approach to 3-Fluoropyrroles

Mei Xie, Zhenli Luo, Chunming Chen, Zhuang Xiong, Jinhui Hu and Jia-Qiang Wu

Org. Lett., 2025, 27, 9920
DOI: 10.1021/acs.orglett.5c02884

Synthesis of Dialkyl-Substituted Monofluoroalkenes via Palladium-Catalyzed Cross-Coupling of Alkyl Carbagermatranes

Chao Wang, Yu-Chao Liu, Meng-Yu Xu and Bin Xiao

Org. Lett., 2021, 23, 4593
DOI: 10.1021/acs.orglett.1c01289

Formation of Fluorovinyl Spiro-[imidazole-indene] and α-Amino-β-naphthalenones via Rh(III)-Catalyzed Cascade C–H Functionalization

Yi Luo, Han-Yi Zhou, Yi-Chi Gang and Lin Dong

Org. Lett., 2022, 24, 6940
DOI: 10.1021/acs.orglett.2c02711

Bi(OTf)3 Enabled C‐F Bond Cleavage in HFIP: Electrophilic Aromatic Formylation with Difluoro(phenylsulfanyl)methane

Nolan M. Betterley, Sutthichat Kerdphon, Suppisak Chaturonrutsamee, Sopanat Kongsriprapan, Panida Surawatanawong, Darunee Soorukram, Manat Pohmakotr, Pher G. Andersson, Vichai Reutrakul and Chutima Kuhakarn

Asian J Org Chem, 2018, 7, 1642
DOI: 10.1002/ajoc.201800313

Synthesis of Fluorine-Containing 6-Arylpurine Derivatives via Cp*Co(III)-Catalyzed C–H Bond Activation

Nanami Murakami, Misaki Yoshida, Tatsuhiko Yoshino and Shigeki Matsunaga

Chem. Pharm. Bull., 2018, 66, 51
DOI: 10.1248/cpb.c17-00797

Stereoselective Palladium‐Catalyzed C−F Bond Alkynylation of Tetrasubstituted gem‐Difluoroalkenes

Qiao Ma, Yanhui Wang and Gavin Chit Tsui

Angewandte Chemie, 2020, 132, 11389
DOI: 10.1002/ange.202002219

Stereoselective Palladium‐Catalyzed C−F Bond Alkynylation of Tetrasubstituted gem‐Difluoroalkenes

Qiao Ma, Yanhui Wang and Gavin Chit Tsui

Angew Chem Int Ed, 2020, 59, 11293
DOI: 10.1002/anie.202002219

Nondirected C–H/C–F Coupling for the Synthesis of α-Fluoro Olefinated Arenes

Sandip Porey, Yogesh Bairagi, Srimanta Guin, Xinglong Zhang and Debabrata Maiti

ACS Catal., 2023, 13, 14000
DOI: 10.1021/acscatal.3c02975

Organocatalytic strategy for hydrophenolation of gem-difluoroalkenes

Douglas L. Orsi, M. Ramu Yadav and Ryan A. Altman

Tetrahedron, 2019, 75, 4325
DOI: 10.1016/j.tet.2019.04.016

Trisubstituted alkenes featuring aryl groups: stereoselective synthetic strategies and applications

Meng-Yao Li, Shuyang Zhai, Xiao-Mei Nong, Ao Gu, Jiatong Li, Guo-Qiang Lin and Yingbin Liu

Sci. China Chem., 2023, 66, 1261
DOI: 10.1007/s11426-022-1515-5

Cp*Rh(III)-Catalyzed Regioselective C(sp3)–H Methylation of 8-Methylquinolines with Organoborons

Rakesh Kumar, Ritika Sharma, Rohit Kumar and Upendra Sharma

Org. Lett., 2020, 22, 305
DOI: 10.1021/acs.orglett.9b04331

Rh(III)-Catalyzed Redox-Neutral C–H Activation/[3 + 2] Annulation of N-Phenoxy Amides with Propargylic Monofluoroalkynes

Xiuhua Zhong, Shuang Lin, Hui Gao, Fu-Xiaomin Liu, Zhi Zhou and Wei Yi

Org. Lett., 2021, 23, 2285
DOI: 10.1021/acs.orglett.1c00418

Two-in-One Role of Benzophenone in Photoinduced C(sp3)–H Monofluoralkenylation: Hydrogen-Atom Transfer and Single-Electron Transfer

Renqin Zhan and Huiying Zeng

J. Org. Chem., 2024, 89, 8272
DOI: 10.1021/acs.joc.4c00650

A highly efficient approach to Z-monofluoroolefin-dehydroamino acid derivatives from gem-difluoroalkenes

Chuangchuang Liu, Yilian Song, Wenjie Ju, Xin Liu, Min Liang and Yingsheng Zhao

Chinese Chemical Letters, 2025, 111167
DOI: 10.1016/j.cclet.2025.111167

Ru(II)/Rh(III)-Catalyzed C(sp3)–C(sp3) Bond Formation through C(sp3)–H Activation: Selective Linear Alkylation of 8-Methylquinolines and Ketoximes with Olefins

Rohit Kumar, Rakesh Kumar, Diksha Parmar, Shiv Shankar Gupta and Upendra Sharma

J. Org. Chem., 2020, 85, 1181
DOI: 10.1021/acs.joc.9b03257

Rh(III)-Catalyzed, Redox-Neutral, C–H Multifluoroalkenylation of Benzamides

Wei Lin, Yifei Qu, Huixuan Zhu, Mei Xie, Jinhui Hu, Zhuang Xiong, Wen-Hua Chen, Jun Xu and Jia-Qiang Wu

Synthesis, 2024, 56, 3045
DOI: 10.1055/a-2343-0676

Cobalt(III)/Rhodium(III)‐Catalyzed Regio‐ and Stereoselective Allylation of 8‐Methylquinoline via sp3 C−H Activation

Na Li, Yahui Wang, Lingheng Kong, Junbiao Chang and Xingwei Li

Adv Synth Catal, 2019, 361, 3880
DOI: 10.1002/adsc.201900220

Rhodium‐Catalyzed Selective C−H Bond Functionalization of Quinolines

Ankit K. Dhiman, Ankita Thakur, Rakesh Kumar and Upendra Sharma

Asian J Org Chem, 2020, 9, 1502
DOI: 10.1002/ajoc.202000341

Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C–H Activation of Nitrones and Coupling with Perfluoroalkylolefins

Yunyun Li, Fang Xie, Yuan Liu, Xifa Yang and Xingwei Li

Org. Lett., 2018, 20, 437
DOI: 10.1021/acs.orglett.7b03775

C–H/C–F functionalization by E-selective ruthenium (II) catalysis

Uttam Dhawa, Daniel Zell, Rongxin Yin, Shintaro Okumura, Masahiro Murakami and Lutz Ackermann

Journal of Catalysis, 2018, 364, 14
DOI: 10.1016/j.jcat.2018.04.019

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation ofgem‐Difluoroalkenes

Tao‐Yan Lin, Zhangjin Pan, Youshao Tu, Shuai Zhu, Hai‐Hong Wu, Yu Liu, Zhiming Li and Junliang Zhang

Angew Chem Int Ed, 2020, 59, 22957
DOI: 10.1002/anie.202008262

Regiocontrolled Rh(III)-catalyzed C C coupling/C N cyclization mediated by distinctive 1,2-migratory insertion of gem‑difluoromethylene allenes: Reaction development and mechanistic insight

Zhi Zhou, Kaifeng Chen, Yi Wang, Xiuhua Zhong, Shuang Lin, Hui Gao and Wei Yi

Chinese Chemical Letters, 2023, 34, 107849
DOI: 10.1016/j.cclet.2022.107849

Transition‐Metal‐Mediated and ‐Catalyzed C−F Bond Activation by Fluorine Elimination

Takeshi Fujita, Kohei Fuchibe and Junji Ichikawa

Angew Chem Int Ed, 2019, 58, 390
DOI: 10.1002/anie.201805292

Rhodium-Catalyzed Merging of 2-Arylquinazolinone and 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Monofluoroolefin Quinazolinone Derivatives

Ning Wang, Qin Yang, Zhihong Deng, Xuechun Mao and Yiyuan Peng

ACS Omega, 2020, 5, 14635
DOI: 10.1021/acsomega.0c01344

Rapid Microwave‐Assisted, Solvent‐Free Approach to Functionalization of 8‐Methylquinolines via Rh‐Catalyzed C(sp3)‐H Activation

You‐Quan Zhu, Jing‐Li He, Yun‐Xia Niu, Ting‐Feng Han and Kun Zhu

ChemistrySelect, 2019, 4, 576
DOI: 10.1002/slct.201803833

Stereoselective β–F Elimination Enabled Redox-Neutral [4 + 1] Annulation via Rh(III)-Catalyzed C–H Activation: Access to Z-Monofluoroalkenyl Dihydrobenzo[d]isoxazole Framework

Hui Gao, Ming Sun, Haiman Zhang, Mengyao Bian, Min Wu, Guoxun Zhu, Zhi Zhou and Wei Yi

Org. Lett., 2019, 21, 5229
DOI: 10.1021/acs.orglett.9b01831

Silver-Catalyzed (Z)-β-Fluoro-vinyl Iodonium Salts from Alkynes: Efficient and Selective Syntheses of Z-Monofluoroalkenes

Alexi T. Sedikides and Alastair J. J. Lennox

J. Am. Chem. Soc., 2024, 146, 15672
DOI: 10.1021/jacs.4c03826

Synthesis of 2,2-diaryl-1,1-difluoroethenes via Pd-catalyzed dehydrosulfonylative cross-coupling of α-[difluoro(phenylsulfonyl)methyl]benzyl tosylates with arylboronic acids

Rui Zhang, Chuanfa Ni, Yanchuan Zhao and Jinbo Hu

Tetrahedron, 2018, 74, 5295
DOI: 10.1016/j.tet.2018.04.054

Rhodium-catalyzed formal [4 + 3] annulation reaction of N-methoxybenzamides with gem‑difluorocyclopropenes: A combination of experimental and theoretical studies

Yimiao He, Limei Tian, Xuexue Chang, Zeming Qu, Yanmin Huang, Chusheng Huang, Qing Sun and Honggen Wang

Chinese Chemical Letters, 2022, 33, 2987
DOI: 10.1016/j.cclet.2022.01.068

Stereoselective Synthesis of Monofluoroalkenes via Photoinduced Direct Monofluoroalkenylation of C(sp³)–H Bonds

Xiao-Yu Lu, Xiang Li, Xin-Ru Hu, Wen-Jing Li and Hao-Yu Dong

Synlett, 2025, 36, 1759
DOI: 10.1055/a-2596-9863

gem‐Difluoromethylene Alkyne‐Enabled Diverse C−H Functionalization and Application to the on‐DNA Synthesis of Difluorinated Isocoumarins

Hui Gao, Shuang Lin, Shuning Zhang, Weijie Chen, Xiawen Liu, Guang Yang, Richard A. Lerner, Hongtao Xu, Zhi Zhou and Wei Yi

Angewandte Chemie, 2021, 133, 1987
DOI: 10.1002/ange.202013052

Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds

Bin Liu, Andrew M. Romine, Camille Z. Rubel, Keary M. Engle and Bing-Feng Shi

Chem. Rev., 2021, 121, 14957
DOI: 10.1021/acs.chemrev.1c00519

Visible-Light-Induced Monofluoroalkenylation and gem-Difluoroallylation of Inactivated C(sp3)–H Bonds via 1,5-Hydrogen Atom Transfer (HAT)

Yanyang Bao, Meifang Tang, Qing Wang, Zhong-Yan Cao, Yanan Wang and Zheliang Yuan

J. Org. Chem., 2023, 88, 3883
DOI: 10.1021/acs.joc.3c00144

Ruthenium(II)-Catalyzed α-Fluoroalkenylation of Oxime Ethers with gem-Difluorostyrenes via C–H Activation and C–F Cleavage

Lili Zhang, Kezuan Deng, Gaorong Wu, Jinyue Yang, Shibiao Tang, Xiaopan Fu, Chengcai Xia and Yafei Ji

J. Org. Chem., 2020, 85, 12670
DOI: 10.1021/acs.joc.0c01842

Progress in Visible-Light Catalyzed C—F Bond Functionalization ofgem-Difluoroalkenes

Zhiqing Li, Xiaoyang Qiu, Jiang Lou and Qiang Wang

Chinese Journal of Organic Chemistry, 2021, 41, 4192
DOI: 10.6023/cjoc202106013

Rh(III)-Catalyzed Chemoselective C–H Alkenylation and [5 + 1] Annulation with Gem-Difluoromethylene Enabled by the Distinctive Fluorine Effect

Jian Yang, Wendi Shi, Weijie Chen, Hui Gao, Zhi Zhou and Wei Yi

J. Org. Chem., 2021, 86, 9711
DOI: 10.1021/acs.joc.1c01012

Synthesis of Indenopyrazole Frameworks via Cascade C–H Functionalization/[3 + 2] Dipolar Cycloaddition/Aromatization Rearrangement Reactions

Min Wu, Ruiqi Wang, Fangyuan Chen, Weijie Chen, Zhi Zhou and Wei Yi

Org. Lett., 2020, 22, 7152
DOI: 10.1021/acs.orglett.0c02506

Detrifluoroacetylation Reaction of Trifluoromethyl‐β‐diketones: Facile Method for the Synthesis of Succinimide Derivatives and 1,4‐Diketones

Li‐Hua Wang and Jing Zhao

Eur J Org Chem, 2018, 2018, 4345
DOI: 10.1002/ejoc.201800680

Metal‐Free Access to (E/Z)‐α‐Fluorovinyl Phosphorus Compounds from gem‐Difluorostyrenes

Yingyuan Peng, Xiaofei Zhang, Xueyu Qi, Qian He, Bin Zhang, Jian Hao and Chunhao Yang

Eur J Org Chem, 2019, 2019, 1170
DOI: 10.1002/ejoc.201801602

Fluoro‐Hydroxylation of gem‐Difluoroalkenes: Synthesis of 18O‐labeled α‐CF3 Alcohols

Jingyu Hu, Yide Yang, Zhengzhao Lou, Chuanfa Ni and Jinbo Hu

Chin. J. Chem., 2018, 36, 1202
DOI: 10.1002/cjoc.201800426

Cp*RhIII‐Catalyzed Sterically Controlled C(sp3)−H Selective Mono‐ and Diarylation of 8‐Methylquinolines with Organoborons**

Rakesh Kumar, Diksha Parmar, Shiv Shankar Gupta, Devesh Chandra, Ankit Kumar Dhiman and Upendra Sharma

Chemistry A European J, 2020, 26, 4396
DOI: 10.1002/chem.201905591

Transition Metal‐Catalyzed C−H Activation/Functionalization of 8‐Methylquinolines

Fatemeh Doraghi, Mohammad Mahdi Aghanour Ashtiani, Mahmoud Ameli, Bagher Larijani and Mohammad Mahdavi

The Chemical Record, 2024, 24
DOI: 10.1002/tcr.202400116

Übergangsmetallvermittelte und ‐katalysierte C‐F‐Bindungsaktivierung durch Fluoreliminierung

Takeshi Fujita, Kohei Fuchibe and Junji Ichikawa

Angewandte Chemie, 2019, 131, 396
DOI: 10.1002/ange.201805292

Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of gem-Difluoroalkenes

Douglas L. Orsi, Justin T. Douglas, Jacob P. Sorrentino and Ryan A. Altman

J. Org. Chem., 2020, 85, 10451
DOI: 10.1021/acs.joc.0c00415

Design and Synthesis of TY‐Phos and Application in Palladium‐Catalyzed Enantioselective Fluoroarylation ofgem‐Difluoroalkenes

Tao‐Yan Lin, Zhangjin Pan, Youshao Tu, Shuai Zhu, Hai‐Hong Wu, Yu Liu, Zhiming Li and Junliang Zhang

Angewandte Chemie, 2020, 132, 23157
DOI: 10.1002/ange.202008262

Chemistry of gem-Difluorovinyl Sulfonates

Cai Zhang

MROC, 2023, 20, 842
DOI: 10.2174/1570193X19666220929114415

Recent Advances in Transition Metal‐Catalyzed Functionalization of gem‐Difluoroalkenes

Suvajit Koley and Ryan A. Altman

Israel Journal of Chemistry, 2020, 60, 313
DOI: 10.1002/ijch.201900173

Rhodium‐Catalyzed Defluorinative Vinylation of gem‐Difluoroalkenes for the Synthesis of 2‐Fluoro‐1,3‐dienes

Shengjin Song, Huan Liu, Lu Wang, Chuan Zhu, Teck‐Peng Loh and Chao Feng

Chin. J. Chem., 2019, 37, 1036
DOI: 10.1002/cjoc.201900197

C(sp3)−H Bond Functionalization of 8‐Methylquinolines

Diksha Parmar, Rohit Kumar and Upendra Sharma

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202401266

Rhodium(III) Catalyzed C(sp3)—H Functionalization

Gaoxu Han, Hongtao Xu and Wei Hou

Chinese Journal of Organic Chemistry, 2022, 42, 391
DOI: 10.6023/cjoc202108012

Rhodium‐Catalyzed C(sp3)–H Arylation of 8‐Methylquinolines with Arylsilanes

Lin Li, Haidong Liu, Yupeng Qian, Guohong Shen, Yun Shi, Jiajie Du and Haiqing Luo

Chin. J. Chem., 2024, 42, 2627
DOI: 10.1002/cjoc.202400429

Stereodivergent Palladium-Catalyzed C–F Bond Functionalization of gem-Difluoroalkenes

Yanhui Wang and Gavin Chit Tsui

Org. Lett., 2024, 26, 5822
DOI: 10.1021/acs.orglett.4c02112

Visible Light‐Mediated Trifluoromethylation of Fluorinated Alkenes via C−F Bond Cleavage

Liu‐Hai Wu, Jun‐Kee Cheng, Liang Shen, Zhi‐Liang Shen and Teck‐Peng Loh

Adv Synth Catal, 2018, 360, 3894
DOI: 10.1002/adsc.201800740

Recent Advances in Alkenyl sp2 C–H and C–F Bond Functionalizations: Scope, Mechanism, and Applications

Ming-Zhu Lu, Jeffrey Goh, Manikantha Maraswami, Zhenhua Jia, Jie-Sheng Tian and Teck-Peng Loh

Chem. Rev., 2022, 122, 17479
DOI: 10.1021/acs.chemrev.2c00032

Rh(III)‐Catalyzed Regioselective Acetylation of sp2 C−H Bond Starting from Paraformaldehyde

Ting Wan, Sidong Du, Chao Pi, Yong Wang, Rongbin Li, Yangjie Wu and Xiuling Cui

ChemCatChem, 2019, 11, 3791
DOI: 10.1002/cctc.201801512

Palladium-Catalyzed Synthesis of Quinolinyl Lactones via Double C(sp3)–H Functionalization

Dinesh G. Thakur, Mahesh A. Sonawane, Raj N. Patel and Subhash Chandra Ghosh

Org. Lett., 2025
DOI: 10.1021/acs.orglett.5c03411

gem‐Difluoromethylene Alkyne‐Enabled Diverse C−H Functionalization and Application to the on‐DNA Synthesis of Difluorinated Isocoumarins

Hui Gao, Shuang Lin, Shuning Zhang, Weijie Chen, Xiawen Liu, Guang Yang, Richard A. Lerner, Hongtao Xu, Zhi Zhou and Wei Yi

Angew Chem Int Ed, 2021, 60, 1959
DOI: 10.1002/anie.202013052

Synthesis of Alkylated Monofluoroalkenes via Fe-Catalyzed Defluorinative Cross-Coupling of Donor Alkenes with gem-Difluoroalkenes

Ling Yang, Wei-Wei Ji, E Lin, Ji-Lin Li, Wen-Xin Fan, Qingjiang Li and Honggen Wang

Org. Lett., 2018, 20, 1924
DOI: 10.1021/acs.orglett.8b00471

Switchable, Reagent-Controlled C(sp3)-H Selective Iodination and Acetoxylation of 8-Methylquinolines

Ming-Lu Zhang, Xing-Long Zhang, Rui-Li Guo, Meng-Yue Wang, Bao-Yin Zhao, Jin-Hui Yang, Qiong Jia and Yong-Qiang Wang

J. Org. Chem., 2022, 87, 5730
DOI: 10.1021/acs.joc.2c00076