Health effects of air pollutant mixtures (volatile organic compounds, particulate matter, sulfur and nitrogen oxides) – a review of the literature

Emese Fazakas, Iulia A. Neamtiu and Eugen S. Gurzau

Reviews on Environmental Health, 2024, 39, 459
DOI: 10.1515/reveh-2022-0252

The emerging roles of particulate matter-changed non-coding RNAs in the pathogenesis of Alzheimer's disease: A comprehensive in silico analysis and review

Hui-Xian Zeng, Shuang-Jian Qin, John Andersson, Shen-Pan Li, Qing-Guo Zeng, Jia-Hui Li, Qi-Zhen Wu, Wen-Jie Meng, Anna Oudin, Katja M. Kanninen, Pasi Jalava, Guang-Hui Dong and Xiao-Wen Zeng

Environmental Pollution, 2025, 366, 125440
DOI: 10.1016/j.envpol.2024.125440

A review of the possible associations between ambient PM2.5 exposures and the development of Alzheimer's disease

Yikai Shou, Yilu Huang, Xiaozheng Zhu, Cuiqing Liu, Yu Hu and Huanhuan Wang

Ecotoxicology and Environmental Safety, 2019, 174, 344
DOI: 10.1016/j.ecoenv.2019.02.086

Air pollution: an emerging risk factor for autism spectrum disorder

Shashank Kumar Ojha and Haitham Amal

Brain Medicine, 2024, 1, 31
DOI: 10.61373/bm024e.0115

Associations between long-term air pollution exposure and the development of amyotrophic lateral sclerosis: A matched case-control study

Daniel Saucier, Mathieu Bélanger, Zikuan Liu, Eric Lavigne and Colleen O'Connell

Environmental Research, 2025, 284, 122232
DOI: 10.1016/j.envres.2025.122232

Rescue of degenerating neurons and cells by stem cell released molecules: using a physiological renormalization strategy

Greg Maguire, Lee Paler, Linda Green, Rosa Mella, Maria Valcarcel and Patricia Villace

Physiol Rep, 2019, 7, e14072
DOI: 10.14814/phy2.14072

Impact of air pollution and occupational inhalation exposures on neurodegenerative disorders: An epigenetic perspective

Paola Monti, Elia Biganzoli and Valentina Bollati

iScience, 2025, 28, 112825
DOI: 10.1016/j.isci.2025.112825

The impact of polar fraction of the fine particulate matter on redox responses in different rat tissues

Joaquim de Paula Ribeiro, Ana Cristina Kalb, Sabrina de Bastos Maya, Adriana Gioda, Pablo Elias Martinez, José Maria Monserrat, Braulio D. Jiménez-Vélez and Carolina Rosa Gioda

Environ Sci Pollut Res, 2019, 26, 32476
DOI: 10.1007/s11356-019-06452-9

Mortality and morbidity due to exposure to ambient air PM10 in Zahedan city, Iran: The AirQ model approach

Mostafa Leili, Farshad Bahrami Asl, Reza Jamshidi and Ali Dehdar

Urban Climate, 2023, 49, 101493
DOI: 10.1016/j.uclim.2023.101493

Long-term exposure to air pollution and mortality in Scotland: A register-based individual-level longitudinal study

Mary Abed Al Ahad, Urška Demšar, Frank Sullivan and Hill Kulu

Environmental Research, 2023, 238, 117223
DOI: 10.1016/j.envres.2023.117223

Towards a more effective REACH legislation in protecting human health

Lode Godderis, Evi De Ryck, Willy Baeyens, Lieve Geerts, Griet Jacobs, Phillippe Maesen, Birgit Mertens, Guy Schroyen, Frank Van Belleghem, Jeroen Vanoirbeek and Nicolas Van Larebeke

Toxicological Sciences, 2024, 199, 194
DOI: 10.1093/toxsci/kfae025

Different components of air pollutants and neurological disorders

Chunlia Fu, Daibing Kuang, He Zhang, Jinxin Ren and Jialong Chen

Front. Public Health, 2022, 10
DOI: 10.3389/fpubh.2022.959921

Long-term evaluation of a low-cost air sensor network for monitoring indoor and outdoor air quality at the community scale

Rachel E. Connolly, Qiao Yu, Zemin Wang, Yu-Han Chen, Jonathan Z. Liu, Ashley Collier-Oxandale, Vasileios Papapostolou, Andrea Polidori and Yifang Zhu

Science of The Total Environment, 2022, 807, 150797
DOI: 10.1016/j.scitotenv.2021.150797

Air pollution is associated with faster cognitive decline in Alzheimer's disease

Young‐gun Lee, Seon‐Jin Yoon, So Hoon Yoon, Sung Woo Kang, Seun Jeon, Minseok Kim, Dong Ah Shin, Chung Mo Nam and Byoung Seok Ye

Ann Clin Transl Neurol, 2023, 10, 964
DOI: 10.1002/acn3.51779

Aerosol pollution, including eroded soils, intensifies cloud growth, precipitation, and soil erosion: A review

Marco Casazza, Massimiliano Lega, Gengyuan Liu, Sergio Ulgiati and Theodore A. Endreny

Journal of Cleaner Production, 2018, 189, 135
DOI: 10.1016/j.jclepro.2018.04.004

From Inhalation to Neurodegeneration: Air Pollution as a Modifiable Risk Factor for Alzheimer’s Disease

Jordi Olloquequi, Roberto Díaz-Peña, Ester Verdaguer, Miren Ettcheto, Carme Auladell and Antoni Camins

IJMS, 2024, 25, 6928
DOI: 10.3390/ijms25136928

Household fuel use, social engagement, and cognitive decline in older Chinese adults: a prospective cohort study based on CHARLS

Afei Qin, Meiqi Wang, Yanqin Chen, Zhenzhen Fu and Long Sun

BMC Geriatr, 2026, 26
DOI: 10.1186/s12877-025-06963-w

Air pollutant mixtures associated with decomposing Sargassum in the Caribbean: Sources, exposure, and potential interactive health effects (Review)

Gary Lutin, Patrick Portecop, Jonathan Florentin, Rémi Neviere, Eric Villenave, Dabor Resiere and Sylvie Bercion

Environmental Pollution, 2026, 398, 128100
DOI: 10.1016/j.envpol.2026.128100

Neurotoxicity of the air-borne particles: From molecular events to human diseases

Fang Liu, Chunyan Liu, Yin Liu, Jiahui Wang, Yibing Wang and Bing Yan

Journal of Hazardous Materials, 2023, 457, 131827
DOI: 10.1016/j.jhazmat.2023.131827

Association between air pollutants with calcaneus ultrasound T-score change in a large Taiwanese population follow-up study

Wei-Yu Su, Da-Wei Wu, Szu-Chia Chen, Chih-Hsing Hung and Chao-Hung Kuo

Environ Sci Pollut Res, 2023, 30, 72607
DOI: 10.1007/s11356-023-27368-5

Air Pollution-Induced Neurotoxicity: The Relationship Between Air Pollution, Epigenetic Changes, and Neurological Disorders

Sebastian Kalenik, Agnieszka Zaczek and Aleksandra Rodacka

IJMS, 2025, 26, 3402
DOI: 10.3390/ijms26073402

Building a Network of Adverse Outcome Pathways (AOPs) Incorporating the Tau-Driven AOP Toward Memory Loss (AOP429)

Maria Tsamou and Erwin L. Roggen

Journal of Alzheimer's Disease Reports, 2022, 6, 271
DOI: 10.3233/ADR-220015

Recent progress in excited-state intramolecular proton transfer-based ratiometry fluorescence probes for environmental detection and monitoring

Savikriti Saini, Selva Kumar Ramasamy and S.K. Ashok Kumar

Trends in Environmental Analytical Chemistry, 2025, 48, e00279
DOI: 10.1016/j.teac.2025.e00279

The association between prenatal exposure to mixed air pollutants and birth defects risk: a population-based study in Tangshan, China

Min Guo, Yuelin Li, Haishuang Li, Yuxia Yang and Hongzhen Zhang

Front. Public Health, 2026, 14
DOI: 10.3389/fpubh.2026.1791132

PM2.5-induced lung injury in rats: Identification of differential circRNAs and analysis of circRNA–miRNA–mRNA regulatory networks

Yunna Jia, Xiqing Zhang, Cuizhu Zhao, Zhenhua Ma, Xiaohui Du, Meng Liu, Qiannan Li, Ye Wang, Xiaojun Liang, Xiuyun Jiang and Yunhang Gao

Ecotoxicology and Environmental Safety, 2026, 309, 119733
DOI: 10.1016/j.ecoenv.2026.119733

Epigenetic Regulation in Exposome-Induced Tumorigenesis: Emerging Roles of ncRNAs

Miguel Ángel Olmedo-Suárez, Ivonne Ramírez-Díaz, Andrea Pérez-González, Alejandro Molina-Herrera, Miguel Ángel Coral-García, Sagrario Lobato, Pouya Sarvari, Guillermo Barreto and Karla Rubio

Biomolecules, 2022, 12, 513
DOI: 10.3390/biom12040513

Air Pollution Reduces the Individuals’ Life Satisfaction Through Health Impairment

Mary Abed Al Ahad

Applied Research Quality Life, 2024, 19, 1049
DOI: 10.1007/s11482-024-10273-5

EV-miRNA associated with environmental air pollution exposures in the MADRES cohort

Helen Bermudez Foley, Sandrah P Eckel, Tingyu Yang, Mario Vigil, Xinci Chen, Carmen Marsit, Shohreh F Farzan, Theresa M Bastain, Rima Habre and Carrie V Breton

Environmental Epigenetics, 2024, 10
DOI: 10.1093/eep/dvae019

Systems chemo-biology analysis of DNA damage response and cell cycle effects induced by coal exposure

Jose F. Torres-Ávila, Lyda Espitia-Pérez, Diego Bonatto, Fernanda Rabaioli da Silva, Iuri Marques de Oliveira, Luís F.O. Silva, Dione Silva Corrêa, Johnny Ferraz Dias, Juliana da Silva and João Antonio Pêgas Henriques

Genet. Mol. Biol., 2020, 43
DOI: 10.1590/1678-4685-gmb-2019-0134

Combined effects of nanoparticles and other environmental contaminants on human health - an issue often overlooked

Valérie Forest

NanoImpact, 2021, 23, 100344
DOI: 10.1016/j.impact.2021.100344

Air Pollution Is Associated with Poor Cognitive Function in Taiwanese Adults

Meng-Chieh Chen, Chen-Feng Wang, Bo-Cheng Lai, Sun-Wung Hsieh, Szu-Chia Chen, Chih-Hsing Hung and Chao-Hung Kuo

IJERPH, 2021, 18, 316
DOI: 10.3390/ijerph18010316

Urbanization, air pollution, and water pollution: Identification of potential environmental risk factors associated with amyotrophic lateral sclerosis using systematic reviews

Daniel Saucier, Pierre Philippe Wilson Registe, Mathieu Bélanger and Colleen O'Connell

Front. Neurol., 2023, 14
DOI: 10.3389/fneur.2023.1108383

Neurodevelopmental toxicity induced by PM2.5 Exposure and its possible role in Neurodegenerative and mental disorders

Xin-qi Liu, Jia Huang, Chao Song, Tian-liang Zhang, Yong-ping Liu and Li Yu

Hum Exp Toxicol, 2023, 42
DOI: 10.1177/09603271231191436

The Yin-Yang of sulfur dioxide: Effect on cognitive function

Prakashkumar Dobariya, Joshua Smith and Swati S. More

Neurotherapeutics, 2025, 22, e00633
DOI: 10.1016/j.neurot.2025.e00633

Particulate matter 2.5 accelerates aging: Exploring cellular senescence and age-related diseases

Sheng-nan Wang, Yan-chuan Shi, Shu Lin and He-fan He

Ecotoxicology and Environmental Safety, 2024, 284, 116920
DOI: 10.1016/j.ecoenv.2024.116920

Physical Exercise in the Context of Air Pollution: An Emerging Research Topic

Yanwei You, Dizhi Wang, Jianxiu Liu, Yuquan Chen, Xindong Ma and Wenkai Li

Front. Physiol., 2022, 13
DOI: 10.3389/fphys.2022.784705

The highly selective and sensitive fluorescent detection of SO2 based on an emissive quinoline derivative probe

Jie Yang, Qing Huang, Hui Yuan, Ling Song, Xing-yu Chen, Ping Shang and Xuan-feng Jiang

Dyes and Pigments, 2023, 214, 111209
DOI: 10.1016/j.dyepig.2023.111209

Overview of PM2.5 and health outcomes: Focusing on components, sources, and pollutant mixture co-exposure

Nan Nan, Zhipeng Yan, Yaru Zhang, Rui Chen, Guohua Qin and Nan Sang

Chemosphere, 2023, 323, 138181
DOI: 10.1016/j.chemosphere.2023.138181

Long-term exposure to multiple air pollutants and risk of Parkinson’s disease: a population-based multipollutant model study

Szu-Ju Chen, Shih-Chun Pan, Chih-Da Wu, Hsun Li, Yue Leon Guo and Chin-Hsien Lin

J Neurol Neurosurg Psychiatry, 2025, 96, 757
DOI: 10.1136/jnnp-2024-334825

Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms

Anushi Shukla, Neha Bunkar, Rajat Kumar, Arpit Bhargava, Rajnarayan Tiwari, Koel Chaudhury, Irina Y. Goryacheva and Pradyumna K. Mishra

Science of The Total Environment, 2019, 656, 760
DOI: 10.1016/j.scitotenv.2018.11.381

The impact of the synergistic effect of SO2 and PM2.5/PM10 on obstructive lung disease in subtropical Taiwan

Te-Yu Chen, Szu-Chia Chen, Chih-Wen Wang, Hung-Pin Tu, Pei-Shih Chen, Stephen Chu-Sung Hu, Chiu-Hui Li, Da-Wei Wu, Chih-Hsing Hung and Chao-Hung Kuo

Front. Public Health, 2023, 11
DOI: 10.3389/fpubh.2023.1229820

The enigma of mitochondrial epigenetic alterations in air pollution-induced neurodegenerative diseases

Sayanti Acharyya, Sruthy Hari Kumar, Apoorva Chouksey, Nikita Soni, Nazim Nazeer and Pradyumna Kumar Mishra

NeuroToxicology, 2024, 105, 158
DOI: 10.1016/j.neuro.2024.10.002

Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer’s disease in the 3xTgAD mouse model

Denise Herr, Katrina Jew, Candace Wong, Andrea Kennell, Robert Gelein, David Chalupa, Alexandria Raab, Günter Oberdörster, John Olschowka, M. Kerry O’Banion and Alison Elder

NeuroToxicology, 2021, 84, 172
DOI: 10.1016/j.neuro.2021.03.010

Review: Woodsmoke and emerging issues

Oyemwenosa N. Avenbuan and Judith T. Zelikoff

Current Opinion in Toxicology, 2020, 22, 12
DOI: 10.1016/j.cotox.2020.02.008

Nature Versus Nurture: Does Proteostasis Imbalance Underlie the Genetic, Environmental, and Age-Related Risk Factors for Alzheimer’s Disease?

Elise Kikis

Healthcare, 2017, 5, 46
DOI: 10.3390/healthcare5030046

PM2.5 Is a Toxic Mixture: Not Just a Matter of Concentration

Sarawut Sangkham

Chem. Res. Toxicol., 2026, 39, 249
DOI: 10.1021/acs.chemrestox.5c00455

Long-term exposure to PM2.5 exacerbates dopaminergic neuronal loss through CpG hypermethylation induced down-regulation of PINK1 and DJ-1 genes

Xiangnan Du, Longfei Guan, Chen Chen, Xuemei Wang and Xiaokun Geng