Understanding titanium-catalysed radical–radical reactions: a DFT study unravels the complex kinetics of ketone–nitrile couplings

Jan Streuff, Daniel Himmel and Sara L. Younas

Dalton Trans., 2018, 47, 5072
DOI: 10.1039/C8DT00643A

Titanium catalysis for the synthesis of fine chemicals – development and trends

Manfred Manßen and Laurel L. Schafer

Chem. Soc. Rev., 2020, 49, 6947
DOI: 10.1039/D0CS00229A

Deoxygenative phosphonation of ketones by titanium

Yuquan Wang, Kai Yin, Xiaobo Pang and Xing-Zhong Shu

Chem. Sci., 2026
DOI: 10.1039/D5SC09520D

Titanium-catalyzed radical-type deuteriodeboronation of arylboronates

Zhihui Wang, Biao Ma, Haocong Li, Yiru Wang and Zhanyu Li

Org. Biomol. Chem., 2025, 23, 6710
DOI: 10.1039/D5OB00837A

ChemInform Abstract: Direct Conjugate Alkylation of α,β‐Unsaturated Carbonyls by TiIII‐Catalyzed Reductive Umpolung of Simple Activated Alkenes.

Plamen Bichovski, Thomas M. Haas, Manfred Keller and Jan Streuff

ChemInform, 2016, 47
DOI: 10.1002/chin.201644023

Titanium Catalyzed the Cross‐Coupling of Nitriles and Alkyl Halides for the Synthesis of Ketones

Fanxiang Zeng, Biao Ma, Yiru Wang, Haocong Li, Minghui Zhang and Zhanyu Li

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.202500222

Titanocene Complexes Applied in Organic Transformations

Mingming Yang, Deying Leng, Zhenhua Wang, Xiu Wang and Ziwei Gao

Catalysts, 2025, 15, 779
DOI: 10.3390/catal15080779

Shining Light on TiIV Complexes: Exceptional Tools for Metallaphotoredox Catalysis

Andrea Fermi, Andrea Gualandi, Giacomo Bergamini and Pier Giorgio Cozzi

Eur J Org Chem, 2020, 2020, 6955
DOI: 10.1002/ejoc.202000966

On Water: Diastereoselective Synthesis of Functionalized 3‐Nitrodihydroquinolin‐4(1H)‐ones Under Catalyst‐Free Conditions

Amalorpavadoss Antony Peter Raj and Thanasekaran Ponpandian

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400748

One-Pot Regio- and Diastereoselective Gold-Catalyzed Propargylation of in Situ Activated Chromones and Consecutive Cyclization

Julio Álvarez-Valle, Sergio Fernández, Cecilia Merino-Robledillo, Ignacio Funes-Ardoiz, Diego Sampedro and Javier Santamaría

Org. Lett., 2024, 26, 10487
DOI: 10.1021/acs.orglett.4c03812

Titanium-Mediated Organic Electrosynthesis

Julius Kuzmin, Cristiana Margarita, Guillermo Ahumada, Mainak Mitra and Helena Lundberg

ACS Catal., 2025, 15, 13377
DOI: 10.1021/acscatal.5c03780

An Efficient Synthesis of Heterogeneous and Hard Bound TiIV‐MCM‐41 Catalyzed Mannich Bases and π‐Conjugated Imines

Shenbagapushpam Muthumanickam, Muthukumar Thennila, Paneerselvam Yuvaraj, Kanthapalam Arun Prasath Lingam and Kodirajan Selvakumar

ChemistrySelect, 2021, 6, 14071
DOI: 10.1002/slct.202103547

Titanocene catalysts with modifiable C-symmetric chiral ligands

Stefan Wiesler, Sara L. Younas, Daniel Kratzert and Jan Streuff

Journal of Organometallic Chemistry, 2020, 919, 121327
DOI: 10.1016/j.jorganchem.2020.121327

An Electrochemical Study of Bis(cyclopentadienyl)titanium(IV) Dichloride in the Presence of Magnesium Ions, Amides or Alkynes

Abdou K. D. Dimé, Yvan Six and Olivier Buriez

Russ J Electrochem, 2021, 57, 85
DOI: 10.1134/S1023193521010031

Exploring Dinuclear Titanium Complexes in Titanium(III) Catalysis

Michael A. Unkrig‐Bau, Sara L. Leijendekker and Jan Streuff

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202401337

Modern applications of low-valent early transition metals in synthesis and catalysis

Evan P. Beaumier, Adam J. Pearce, Xin Yi See and Ian A. Tonks

Nat Rev Chem, 2018, 3, 15
DOI: 10.1038/s41570-018-0059-x

Novel stereoselective 1,2-rearrangement of Swaminathan ketone derivatives bearing a 7-membered ring under solvolysis conditions

Kohei Inomata and Sanami Narita

Tetrahedron Letters, 2020, 61, 151542
DOI: 10.1016/j.tetlet.2019.151542

The Proven Versatility of Cp2TiCl

Antonio Rosales Martínez, Laura Pozo Morales, Emilio Díaz Ojeda, María Castro Rodríguez and Ignacio Rodríguez-García

J. Org. Chem., 2021, 86, 1311
DOI: 10.1021/acs.joc.0c01233

One Pot Synthesis of γ‐Benzopyranones via Iron‐Catalyzed Aerobic Oxidation and Subsequent 4‐Dimethylaminopyridine Catalyzed 6‐endo Cyclization

Di Zhai, Lingzhu Chen, Minqiang Jia and Shengming Ma

Adv Synth Catal, 2018, 360, 153
DOI: 10.1002/adsc.201700993

Recent Advances in Titanium Radical Redox Catalysis

Terry McCallum, Xiangyu Wu and Song Lin

J. Org. Chem., 2019, 84, 14369
DOI: 10.1021/acs.joc.9b02465

Cp2TiCl: An Ideal Reagent for Green Chemistry?

María Castro Rodríguez, Ignacio Rodríguez García, Roman Nicolay Rodríguez Maecker, Laura Pozo Morales, J. Enrique Oltra and Antonio Rosales Martínez

Org. Process Res. Dev., 2017, 21, 911
DOI: 10.1021/acs.oprd.7b00098

Construction of multifunctional heterocycles bearing aza-quaternary carbons by titanocene-catalyzed umpolung reactions

Jiang-Tao Cheng, Xiao Zheng and Pei-Qiang Huang

Tetrahedron, 2019, 75, 1612
DOI: 10.1016/j.tet.2018.11.067

Titanocene dichloride: A new green reagent in organic chemistry

Antonio Rosales Martínez, María Castro Rodríguez, Ignacio Rodríguez-García, Laura Pozo Morales and Roman Nicolay Rodríguez Maecker

Chinese Journal of Catalysis, 2017, 38, 1659
DOI: 10.1016/S1872-2067(17)62894-8

Development of an Efficient Synthesis of rac‐3‐Demethoxyerythratidinone via a Titanium(III) Catalyzed Imine‐Nitrile Coupling

Hieu‐Trinh Luu and Jan Streuff

Eur J Org Chem, 2019, 2019, 139
DOI: 10.1002/ejoc.201801479

A Titanium‐Catalyzed Reductive α‐Desulfonylation

Christoph Kern, Jan Selau and Jan Streuff

Chemistry A European J, 2021, 27, 6178
DOI: 10.1002/chem.202005400

Development, Scope, and Applications of Titanium(III)‐Catalyzed Cyclizations to Aminated N‐Heterocycles

Leonardus H. Leijendekker, Jens Weweler, Tobias M. Leuther, Daniel Kratzert and Jan Streuff

Chemistry A European J, 2019, 25, 3382
DOI: 10.1002/chem.201805909

Reductive Umpolung and Defunctionalization Reactions through Higher-Order Titanium(III) Catalysis

Jan Streuff

Synlett, 2023, 34, 314
DOI: 10.1055/s-0042-1751391

Tetrasubstituted Chromanone Synthesis by a Tandem Oxa‐Michael/Michael Addition Reaction of 2‐Hydroxyacetophenones and Alkynyl Nitriles

Chandresh Kumari, Narendra Prasad Sahoo, Madan Kumar and Avijit Goswami

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202401061

Intermolecular Reductive Couplings of Arylidene Malonates via Lewis Acid/Photoredox Cooperative Catalysis

Benjamin R. McDonald and Karl A. Scheidt

Org. Lett., 2018, 20, 6877
DOI: 10.1021/acs.orglett.8b02893

Alternative Chiral Preparations of a Swaminathan Ketone via Asymmetric Aldol Reactions Mediated by Chiral Amines Bearing a Pyrrolidine

Kohei Inomata, Yuichi Akahane and Arisa Miura

HETEROCYCLES, 2020, 100, 12
DOI: 10.3987/COM-19-14124