Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 mitigate alcoholic steatosis in mice by inhibiting LPS-mediated NF-κB activation through restoration of the disturbed gut microbiota

Won-Gyeong Kim, Hye In Kim, Eun Kyung Kwon, Myung Joo Han and Dong-Hyun Kim

Food Funct., 2018, 9, 4255
DOI: 10.1039/C8FO00252E

Pathogenesis, Early Diagnosis, and Therapeutic Management of Alcoholic Liver Disease

Ling-Zu Kong, Nisansala Chandimali, Ying-Hao Han, Dong-Ho Lee, Ji-Su Kim, Sun-Uk Kim, Tae-Don Kim, Dong Kee Jeong, Hu-Nan Sun, Dong Sun Lee and Taeho Kwon

IJMS, 2019, 20, 2712
DOI: 10.3390/ijms20112712

Fish Oil Reduces Hepatic Injury by Maintaining Normal Intestinal Permeability and Microbiota in Chronic Ethanol-Fed Rats

Jiun-Rong Chen, Ya-Ling Chen, Hsiang-Chi Peng, Yu-An Lu, Hsiao-Li Chuang, Hsiao-Yun Chang, Hsiao-Yun Wang, Yu-Ju Su and Suh-Ching Yang

Gastroenterology Research and Practice, 2016, 2016, 1
DOI: 10.1155/2016/4694726

The current state of research for psychobiotics use in the management of psychiatric disorders–A systematic literature review

Octavian Vasiliu

Front. Psychiatry, 2023, 14
DOI: 10.3389/fpsyt.2023.1074736

Advances in the Study of Selenium‐Enriched Probiotics: From the Inorganic Se into Se Nanoparticles

Dan Xiao, Tong Li, Xin Huang, Kongdi Zhu, Zimeng Li, Yulan Dong, Lianshun Wang and Jiaqiang Huang

Molecular Nutrition Food Res, 2023, 67
DOI: 10.1002/mnfr.202300432

Alcohol or Gut Microbiota: Who Is the Guilty?

Marica Meroni, Miriam Longo and Paola Dongiovanni

IJMS, 2019, 20, 4568
DOI: 10.3390/ijms20184568

Ameliorative effects of atractylodin on intestinal inflammation and co-occurring dysmotility in both constipation and diarrhea prominent rats

Changchun Yu, Yongjian Xiong, Dapeng Chen, Yanli Li, Bin Xu, Yuan Lin, Zeyao Tang, Chunling Jiang and Li Wang

Korean J Physiol Pharmacol, 2017, 21, 1
DOI: 10.4196/kjpp.2017.21.1.1

Impacts of fish oil on the gut microbiota of rats with alcoholic liver damage

Ya-Ling Chen, Hitoshi Shirakawa, Nien-Shan Lu, Hsiang-Chi Peng, Qian Xiao and Suh-Ching Yang

The Journal of Nutritional Biochemistry, 2020, 86, 108491
DOI: 10.1016/j.jnutbio.2020.108491

Lactobacillus spp. reduces ethanol‑induced liver oxidative stress and inflammation in a mouse model of alcoholic steatohepatitis

Pei-Shan Hsieh, Ching-Wei Chen, Yi-Wei Kuo and Hsieh-Hsun Ho

Exp Ther Med, 2021, 21
DOI: 10.3892/etm.2021.9619

Targeting gut microbiota in liver disease: A pharmacological approach for hepatic encephalopathy and beyond

Andres Manuel Vargas-Beltran, Stuart Javier Mialma-Omana and Diego Omar Vivanco-Tellez

World J Gastrointest Pharmacol Ther, 2025, 16
DOI: 10.4292/wjgpt.v16.i4.110271

Prebiotic, Probiotic, and Synbiotic Consumption Alter Behavioral Variables and Intestinal Permeability and Microbiota in BTBR Mice

Jodi E. Nettleton, Teja Klancic, Alana Schick, Ashley C. Choo, Ning Cheng, Jane Shearer, Stephanie L. Borgland, Jong M. Rho and Raylene A. Reimer

Microorganisms, 2021, 9, 1833
DOI: 10.3390/microorganisms9091833

Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats

Yi-Wen Chien, Hsiang-Chi Peng, Ya-Ling Chen, Man-Hui Pai, Hsiao-Yun Wang, Hsiao-Li Chuang and Suh-Ching Yang

Mediators of Inflammation, 2017, 2017, 1
DOI: 10.1155/2017/5801768

Wheat embryo globulin protects against acute alcohol-induced liver injury in mice

Canrui Yang, Ai-Mei Liao, Yixiang Cui, Guanghai Yu, Yinchen Hou, Long Pan, Wenjing Chen, Shuainan Zheng, Xiaoxiao Li, Jiarui Ma, Jiangying He and Jihong Huang

Food and Chemical Toxicology, 2021, 153, 112240
DOI: 10.1016/j.fct.2021.112240

Overview of the Importance of Biotics in Gut Barrier Integrity

Aleksandra Maria Kocot, Elżbieta Jarocka-Cyrta and Natalia Drabińska

IJMS, 2022, 23, 2896
DOI: 10.3390/ijms23052896

Hepatoenteric Protective Effect of Melanin from Inonotus hispidus on Acute Alcoholic Liver Injury in Mice

Yuan Yuan, Fuquan Wu, Fengpei Zhang, Xiaomin Li, Xiaoping Wu and Junsheng Fu

Molecular Nutrition Food Res, 2023, 67
DOI: 10.1002/mnfr.202200562

Idiosyncratic Drug-Induced Liver Injury: Is Drug-Cytokine Interaction the Linchpin?

Robert A. Roth, Ashley R. Maiuri and Patricia E. Ganey

The Journal of Pharmacology and Experimental Therapeutics, 2017, 360, 368
DOI: 10.1124/jpet.116.237578

Protective Effect of Enterococcus faecium and Its Extracellular Vesicles Against Ethanol-Induced Intestinal Injury

Meiying Luo, Suqian Li, Junhang Sun, Limin Wei, Xin Feng, Huihua Zhang and Qien Qi

Foodborne Pathogens and Disease, 2024
DOI: 10.1089/fpd.2024.0061

Effects of inulin-type fructans, galacto-oligosaccharides and related synbiotics on inflammatory markers in adult patients with overweight or obesity: A systematic review

Ricardo Fernandes, Vinicius A. do Rosario, Michel C. Mocellin, Marilyn G.F. Kuntz and Erasmo B.S.M. Trindade

Clinical Nutrition, 2017, 36, 1197
DOI: 10.1016/j.clnu.2016.10.003

Bacillus coagulans–Pectin Synbiotic Modulates Gut Microbiota Composition and Attenuates Ethanol-Induced Alcoholic Liver Disease in Mice

Zhenzhen Liu, Tong Liu, Yurong Fan and Ziyang Jiang

Microorganisms, 2025, 13, 1986
DOI: 10.3390/microorganisms13091986

Do gut microbiome‐targeted therapies improve liver function in cirrhotic patients? A systematic review and meta‐analysis

Honglin Jiang, Ning Xu, Wei Zhang, Hongjian Wei, Yue Chen, Qingwu Jiang and Yibiao Zhou

J of Gastro and Hepatol, 2023, 38, 1900
DOI: 10.1111/jgh.16329

Effect of procyanidins on lipid metabolism and inflammation in rats exposed to alcohol and iron

Amara Lobo, Ying Liu, Yuqing Song, Song Liu, Rui Zhang, Hui Liang and Hui Xin

Heliyon, 2020, 6, e04847
DOI: 10.1016/j.heliyon.2020.e04847

Does chronic inflammation cause acute inflammation to spiral into hyper‐inflammation in a manner modulated by diet and the gut microbiome, in severe Covid‐19?

Manni Luthra‐Guptasarma and Purnananda Guptasarma

BioEssays, 2021, 43
DOI: 10.1002/bies.202000211

Gut microbiota-modulating agents in alcoholic liver disease: Links between host metabolism and gut microbiota

Jang Han Jung, Sung-Eun Kim, Ki Tae Suk and Dong Joon Kim

Front. Med., 2022, 9
DOI: 10.3389/fmed.2022.913842

Synbiotic effects of β-glucans from cauliflower mushroom and Lactobacillus fermentum on metabolic changes and gut microbiome in estrogen-deficient rats

Seong-Yeop Jeong, Suna Kang, Cao Shi Hua, Zhang Ting and Sunmin Park

Genes Nutr, 2017, 12
DOI: 10.1186/s12263-017-0585-z

The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation in Rats with Ethanol-Induced Liver Damage

Qian Xiao, Yi-Hsiu Chen, Satwika Arya Pratama, Ya-Ling Chen, Hitoshi Shirakawa, Hsiang-Chi Peng and Suh-Ching Yang

Nutrients, 2021, 13, 2788
DOI: 10.3390/nu13082788

Are Probiotics Effective in Targeting Alcoholic Liver Diseases?

Meegun Hong, Dae Hee Han, Jitaek Hong, Dong Joon Kim and Ki Tae Suk

Probiotics & Antimicro. Prot., 2019, 11, 335
DOI: 10.1007/s12602-018-9419-6

Alcohol, microbiome, and their effect on psychiatric disorders

Thomas Hillemacher, Oliver Bachmann, Kai G. Kahl and Helge Frieling

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2018, 85, 105
DOI: 10.1016/j.pnpbp.2018.04.015

Microbial treatment of alcoholic liver disease: A systematic review and meta-analysis

Qinjian Wang, Jiangmin Shi, Min Zhao, Gaoyi Ruan, Zebin Dai, Yilang Xue, Dibang Shi, Changlong Xu, Ouyue Yu, Fangyan Wang and Zhanxiong Xue

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.1054265

Lactobacillus acidophilus and vitamin C attenuate ethanol‑induced intestinal and liver injury in mice

Xing Lu and Fengmei Wang

Exp Ther Med, 2021, 22
DOI: 10.3892/etm.2021.10438

Multifaceted role of synbiotics as nutraceuticals, therapeutics and carrier for drug delivery

Rubiya Khursheed, Monica Gulati, Sheetu Wadhwa, Sukriti Vishwas, Deep Shikha Sharma, Leander Corrie, Aftab Alam, Sulaiman Mohammed Alnasser, Faris F. Aba Alkhayl, Zeenat Parveen, Srinivas Nammi, Dinesh Kumar Chellappan, Gaurav Gupta, Flavia Zacconi, Amie Steel, Jon Adams, Niraj Kumar Jha, Kamal Dua and Sachin Kumar Singh

Chemico-Biological Interactions, 2022, 368, 110223
DOI: 10.1016/j.cbi.2022.110223

Fish oil up-regulates hepatic autophagy in rats with chronic ethanol consumption

Nien-Shan Lu, Wan-Chun Chiu, Ya-Ling Chen, Hsiang-Chi Peng, Hitoshi Shirakawa and Suh-Ching Yang

The Journal of Nutritional Biochemistry, 2020, 77, 108314
DOI: 10.1016/j.jnutbio.2019.108314

Protective effect of Djulis ( Chenopodium formosanum ) and its bioactive compounds against carbon tetrachloride-induced liver injury, in vivo

Chin-Chen Chu, Shih-Ying Chen, Charng-Cherng Chyau, Zi-Han Fu, Ching-Chih Liu and Pin-Der Duh

Journal of Functional Foods, 2016, 26, 585
DOI: 10.1016/j.jff.2016.08.025

Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease

Xin Chi, Calvin Q. Pan, Shunai Liu, Danying Cheng, Ziwen Cao, Huichun Xing and Alessandro Granito

Canadian Journal of Gastroenterology and Hepatology, 2020, 2020, 1
DOI: 10.1155/2020/6629196

Heme oxygenase-1 alleviates alcoholic liver steatosis: histopathological study

Sarawoot Palipoch, Phanit Koomhin, Chuchard Punsawad, Prasit Na-Ek, Apsorn Sattayakhom and Prasit Suwannalert

J Toxicol Pathol, 2016, 29, 7
DOI: 10.1293/tox.2015-0035

Protective Effect of Aplysin Supplementation on Intestinal Permeability and Microbiota in Rats Treated with Ethanol and Iron

Yan Ma, Ruiying Li, Ying Liu, Man Liu and Hui Liang

Nutrients, 2018, 10, 681
DOI: 10.3390/nu10060681

Targeted Approaches for In Situ Gut Microbiome Manipulation

Hui Ling Lee, Haosheng Shen, In Young Hwang, Hua Ling, Wen Shan Yew, Yung Seng Lee and Matthew Wook Chang

Genes, 2018, 9, 351
DOI: 10.3390/genes9070351

Nutritional and microbiota-based therapeutic interventions for alcohol-associated liver disease: From pathogenesis to therapeutic insights

Shagun Rangra, Dhwani Rana, Arvee Prajapati, Derajram Benival, Pradeep Dwivedi and Amit Mandoli

Life Sciences, 2024, 352, 122852
DOI: 10.1016/j.lfs.2024.122852

Precision medicine in alcoholic and nonalcoholic fatty liver disease via modulating the gut microbiota

Sena Bluemel, Brandon Williams, Rob Knight and Bernd Schnabl

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016, 311, G1018
DOI: 10.1152/ajpgi.00245.2016

Effects of Fish Oil on Lipid Metabolism and Its Molecular Biological Regulators in Chronic Ethanol-Fed Rats

Hsiao-Yun Wang, Hsiang-Chi Peng, Yi-Wen Chien, Ya-Ling Chen, Nien-Shan Lu and Suh-Ching Yang

Nutrients, 2018, 10, 802
DOI: 10.3390/nu10070802

Sex-Specific Effects of Synbiotic Exposure in Mice on Addictive-Like Behavioral Alterations Induced by Chronic Alcohol Intake Are Associated With Changes in Specific Gut Bacterial Taxa and Brain Tryptophan Metabolism

Nieves Pizarro, Elk Kossatz, Pedro González, Alba Gamero, Emma Veza, Cristina Fernández, Toni Gabaldón, Rafael de la Torre and Patricia Robledo

Front. Nutr., 2021, 8
DOI: 10.3389/fnut.2021.750333

Effects of synbiotic supplementation on microbiota-derived protein-bound uremic toxins, systemic inflammation, and biochemical parameters in patients on hemodialysis: A double-blind, placebo-controlled, randomized clinical trial

Soheila Mirzaeian, Sahar Saraf-Bank, Mohammad Hassan Entezari, Azita Hekmatdoost, Awat Feizi and Abdolamir Atapour

Nutrition, 2020, 73, 110713
DOI: 10.1016/j.nut.2019.110713

Synbiotics Alleviate Hepatic Damage, Intestinal Injury and Muscular Beclin-1 Elevation in Rats after Chronic Ethanol Administration

Yi-Hsiu Chen, Wan-Chun Chiu, Qian Xiao, Ya-Ling Chen, Hitoshi Shirakawa and Suh-Ching Yang

IJMS, 2021, 22, 12547
DOI: 10.3390/ijms222212547

Diet-Regulating Microbiota and Host Immune System in Liver Disease

Jung A Eom, Goo Hyun Kwon, Na Yeon Kim, Eun Ju Park, Sung Min Won, Jin Ju Jeong, Ganesan Raja, Haripriya Gupta, Yoseph Asmelash Gebru, Satyapriya Sharma, Ye Rin Choi, Hyeong Seop Kim, Sang Jun Yoon, Ji Ye Hyun, Min Kyo Jeong, Hee Jin Park, Byeong Hyun Min, Mi Ran Choi, Dong Joon Kim and Ki Tae Suk

IJMS, 2021, 22, 6326
DOI: 10.3390/ijms22126326

Association between circulating inflammatory molecules and alcoholic liver disease in men

Bao-Ge Qu, Weimin Bi, Yi-Guo Jia, Yuan-Xun Liu, Hui Wang, Ji-Liang Su, Li-Li Liu, Zhong-Dong Wang, Ya-Fei Wang, Xing-Hai Han, Jin-Dun Pan, Guang-Ying Ren and Wen-Juan Hu

Cell Stress and Chaperones, 2016, 21, 865
DOI: 10.1007/s12192-016-0711-7

Pathogenesis of Alcohol-Associated Liver Disease

Natalia A. Osna, Karuna Rasineni, Murali Ganesan, Terrence M. Donohue and Kusum K. Kharbanda

Journal of Clinical and Experimental Hepatology, 2022, 12, 1492
DOI: 10.1016/j.jceh.2022.05.004

Fermented Lentinus edodes extract containing α-glucan ameliorates concanavalin A-induced autoimmune hepatitis in mice

Xin Hu, Dan Cheng, Yingxia Zhang, Po Li, Xiaoping Wu and Junsheng Fu

Food Science and Human Wellness, 2024, 13, 2102
DOI: 10.26599/FSHW.2022.9250175

A New Perspective on Fish Oil: The Prevention of Alcoholic Liver Disease

Suh-Ching Yang

J. Oleo Sci., 2021, 70, 1531
DOI: 10.5650/jos.ess21216

Hepatoprotection by Traditional Essence of Ginseng against Carbon Tetrachloride—Induced Liver Damage

Yi-Ju Hsu, Chao-Yun Wang, Mon-Chien Lee and Chi-Chang Huang

Nutrients, 2020, 12, 3214
DOI: 10.3390/nu12103214

Probiotics, prebiotics, and synbiotics in nonalcoholic fatty liver disease and alcohol-associated liver disease

Benedikt Kaufmann, Nick Seyfried, Daniel Hartmann and Phillipp Hartmann

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2023, 325, G42
DOI: 10.1152/ajpgi.00017.2023

Alcoholic Liver Disease in the Asian–Pacific Region with High Prevalence of Chronic Viral Hepatitis

Sien-Sing Yang

Journal of Medical Ultrasound, 2016, 24, 93
DOI: 10.1016/j.jmu.2016.08.010

The Preliminary Results for Evaluating Cocoa Butter’s Hepatoprotective Effects against Lipid Accumulation and Inflammation in Adult Male Rats Chronically Fed Ethanol

Hsiao-Yun Chang, Jiun-Rong Chen, Yi-Hsiu Chen, Qian Xiao, Ya-Ling Chen and Suh-Ching Yang

Bioengineering, 2022, 9, 526
DOI: 10.3390/bioengineering9100526

Effects of fish oil on insulin resistance in the brains of rats with alcoholic liver damage

Zi-Yu Liu, Qian Xiao, Yi-Hsiu Chen, Hitoshi Shirakawa, Jing-Huei Lai, Yung-Hsiao Chiang and Suh-Ching Yang

Journal of Functional Foods, 2024, 120, 106369
DOI: 10.1016/j.jff.2024.106369

Drug gastrointestinal absorption in rat: Strain and gender differences

Davinia Oltra-Noguera, Victor Mangas-Sanjuan, Isabel González-Álvarez, Sarin Colon-Useche, Marta González-Álvarez and Marival Bermejo

European Journal of Pharmaceutical Sciences, 2015, 78, 198
DOI: 10.1016/j.ejps.2015.07.021

Diet, food components and the intestinal barrier

J. P. Gleeson

Nutrition Bulletin, 2017, 42, 123
DOI: 10.1111/nbu.12260