Flavans with cytotoxic activity from the stem and root bark of Daphne giraldii

Qian Sun, Fei-Fei Li, Di Wang, Jie Wu, Guo-Dong Yao, Xue Li, Ling-Zhi Li, Qing-Bo Liu, Xiao-Xiao Huang and Shao-Jiang Song

RSC Adv., 2016, 6, 55919
DOI: 10.1039/C6RA08537G

Isolation of cytotoxic daphnane-type and tigliane-type diterpenoids from Daphne genkwa using MetGem software

Si-Hui Mi, Zhi-Kang Duan, Yu-Jue Wang, Shu-Hui Dong, Peng Zhao, Guo-Dong Yao, Qing-Bo Liu, Bin Lin, Shao-Jiang Song and Xiao-Xiao Huang

New J. Chem., 2023, 47, 1517
DOI: 10.1039/D2NJ05276H

Natural Products Research in China From 2015 to 2016

Haishan Liu, Guoliang Zhu, Yaqin Fan, Yuqi Du, Mengmeng Lan, Yibo Xu and Weiming Zhu

Front. Chem., 2018, 6
DOI: 10.3389/fchem.2018.00045

Phytochemistry and Pharmacological Activities of the Diterpenoids from the Genus Daphne

Yi-Wen Nie, Yuan Li, Lan Luo, Chun-Yan Zhang, Wei Fan, Wei-Ying Gu, Kou-Rong Shi, Xiao-Xiang Zhai and Jian-Yong Zhu

Molecules, 2021, 26, 6598
DOI: 10.3390/molecules26216598

Guided isolation of daphnane-type diterpenes from Daphne genkwa by molecular network strategies

Si-Hui Mi, Peng Zhao, Qian Li, Hao Zhang, Rui Guo, Yu-Yang Liu, Bin Lin, Guo-Dong Yao, Shao-Jiang Song and Xiao-Xiao Huang

Phytochemistry, 2022, 198, 113144
DOI: 10.1016/j.phytochem.2022.113144

Assignment of the stereostructures of sesquiterpenoids from the roots of Daphne genkwa via quantum chemical calculations

Jie Wang, Qiang Ren, Yang-Yang Zhang, Rui Guo, Bin Lin, Xiao-Xiao Huang and Shao-Jiang Song

Fitoterapia, 2019, 138, 104352
DOI: 10.1016/j.fitote.2019.104352

Daphnane Diterpenoids from Daphne genkwa Inhibit PI3K/Akt/mTOR Signaling and Induce Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells

Rong-Rong Pan, Chun-Yan Zhang, Yuan Li, Bing-Bing Zhang, Liang Zhao, Ying Ye, Ya-Nan Song, Miao Zhang, Hong-Yun Tie, Hong Zhang and Jian-Yong Zhu

J. Nat. Prod., 2020, 83, 1238
DOI: 10.1021/acs.jnatprod.0c00003

Neogenkwanine I from the flower buds of Daphne genkwa with its stereostructure confirmation using quantum calculation profiles and antitumor evaluation

Xue-Wen Hou, Shuang Han, Ying-Ying Zhang, Hai-Bi Su, Pin-Yi Gao, Ling-Zhi Li and Shao-Jiang Song

Natural Product Research, 2020, 34, 405
DOI: 10.1080/14786419.2018.1536133

Sesquiterpenes and lignans from the flower buds of Daphne genkwa and their nitric oxide inhibitory activities

Chun-Yang Zhang, Lan Luo, Jing Xia, Ya-Nan Song, Li-Jun Zhang, Miao Zhang, Khalid Rahman, Yin Ye, Hong Zhang and Jian-Yong Zhu

Natural Product Research, 2018, 32, 2893
DOI: 10.1080/14786419.2017.1389937

Daphnane-Type Diterpenes from Stelleropsis tianschanica and Their Antitumor Activity

Xiaoyan He, Xiatiguli Abulizi, Xiaowan Li, Guoxu Ma, Zhaocui Sun, Hongyan Wei, Xudong Xu, Leiling Shi and Jing Zhang

Molecules, 2022, 27, 5701
DOI: 10.3390/molecules27175701

Target isolation of cytotoxic diterpenoid esters and orthoesters from Daphne tangutica maxim based on molecular networking

Rui Guo, Qian Li, Si-Hui Mi, Shu-He Jia, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang, Yu-Yang Liu and Shao-Jiang Song

Phytochemistry, 2022, 203, 113358
DOI: 10.1016/j.phytochem.2022.113358

Identification and insights into the uncommon configuration of novel histone lysine acetyltransferase PCAF and methyltransferase GLP inhibitors from Wikstroemia chamaedaphne by molecular docking, and in vitro assessment

Xuefen Hou, Tongtong Yu, Choe hyok chol, Jingkai An, Lin Zhang, Meijia Sun, Jasmin Mecinović, Pinyi Gao and Lingzhi Li

International Journal of Biological Macromolecules, 2025, 304, 140601
DOI: 10.1016/j.ijbiomac.2025.140601

Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery

Kouharu Otsuki and Wei Li

J Nat Med, 2023, 77, 625
DOI: 10.1007/s11418-023-01713-x

Daphnane-type diterpenes from genus Daphne and their anti-tumor activity

Zi-lin Hou, Guo-dong Yao and Shao-jiang Song

Chinese Herbal Medicines, 2021, 13, 145
DOI: 10.1016/j.chmed.2020.09.006

Genkwadane F—I, New Daphnane‐type Diterpenes from the Flower Buds of Daphne genkwa Sieb.et Zucc. Exhibit Anti‐tumor Activities via Inducing Apoptosis

Xuewen Hou, Jingjie Chen, Xuefen Hou, Pinyi Gao, Jinlin Wang, Shaojiang Song and Lingzhi Li

Chin. J. Chem., 2020, 38, 1600
DOI: 10.1002/cjoc.202000187

Chiral Separation of Cytotoxic Flavan Derivatives from Daphne giraldii

Fei-Fei Li, Qian Sun, Di Wang, Sen Liu, Bin Lin, Chun-Ting Liu, Ling-Zhi Li, Xiao-Xiao Huang and Shao-Jiang Song

J. Nat. Prod., 2016, 79, 2236
DOI: 10.1021/acs.jnatprod.6b00305

Vulgarisins B–D, three novel diterpenoids with a rare skeleton isolated from Prunella vulgaris Linn

Hua-Yong Lou, Lian Jin, Tao Huang, Dao-Ping Wang, Guang-Yi Liang and Wei-Dong Pan

Tetrahedron Letters, 2017, 58, 401
DOI: 10.1016/j.tetlet.2016.12.029

New daphnane diterpenoidal 1,3,4-oxdiazole derivatives as potential anti-hepatoma agents: Synthesis, biological evaluation and molecular modeling studies

Xinyi Wang, Yujue Wang, Zijian Liu, Hongwei Zhao, Guo-Dong Yao, Qingbo Liu and Shao-Jiang Song

Bioorganic Chemistry, 2024, 145, 107208
DOI: 10.1016/j.bioorg.2024.107208

Daphne genkwa: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine

Yue Hu, Rongrong Pan, Yi Wang, Minghua Ma, Ying Peng, Weiqing Fan, Ruoxi Zhang, Hua Nian and Jianyong Zhu

Fitoterapia, 2024, 177, 106089
DOI: 10.1016/j.fitote.2024.106089

Chemical constituents from the flower buds of Daphne genkwa (Thymelaeaceae)

Xuefen Hou, Xuewen Hou and Lingzhi Li

Biochemical Systematics and Ecology, 2020, 91, 104055
DOI: 10.1016/j.bse.2020.104055

Bioactive daphnane diterpenes from the flower buds of Daphne genkwa (Thymelaeaceae)

Qingsong Zhu, Hongbin Duan, Lijun Yang, Wei Luo, Tingting Diao, Jiaojiao Hua, Zexia Wang, Qiong Chen, Xinrong Qiao, Jingyi Li and Nailiang Zhu

Natural Product Research, 2025, 39, 6727
DOI: 10.1080/14786419.2024.2385700

Diterpenes from buds of Wikstroemia chamaedaphne showing anti-hepatitis B virus activities

Shi-Fei Li, Ying-Ying Jiao, Zhi-Qiang Zhang, Jian-Bin Chao, Jie Jia, Xun-Long Shi and Li-Wei Zhang

Phytochemistry, 2018, 151, 17
DOI: 10.1016/j.phytochem.2018.01.021

Anti-HIV Tigliane-Type Diterpenoids from the Aerial Parts of Wikstroemia lichiangensis

Di Zhou, Kouharu Otsuki, Mi Zhang, Gang Chen, Zi-Song Bai, Haotian Yu, Takashi Kikuchi, Li Huang, Chin-Ho Chen, Wei Li and Ning Li

J. Nat. Prod., 2022, 85, 1658
DOI: 10.1021/acs.jnatprod.1c01195

Anti-HIV diterpenoids from Daphne pseudomezereum

Kouharu Otsuki, Chihiro Hosoya, Riko Takamiya, Mayu Kimura, Takashi Kikuchi, Li Huang, Chin-Ho Chen and Wei Li

Phytochemistry, 2025, 232, 114366
DOI: 10.1016/j.phytochem.2024.114366

Natural promising daphnane diterpenoids: An integrated review of their sources, structural classification, biological activities, and synthesis

Kang Ding, Xuege Pan, Weifeng Yin, Lin Li, Hongjin Bai, Maoli Bai, Jiekun Xu, Jun He and Weiku Zhang

Phytochemistry, 2025, 233, 114376
DOI: 10.1016/j.phytochem.2024.114376

Tigliane-and daphnane-type diterpenoids from the buds of Daphne genkwa with their cytotoxic activities

Ying Chen, Cai-Lin Zhao, Wei Dong, Fei-Fan Song, Li-Na Guo, Hong-Lian Zhang, Lv Zhen, Li Li, Jin Ye and Bo Song

Natural Product Research, 2023, 37, 3163
DOI: 10.1080/14786419.2022.2147168

A comprehensive review of topoisomerase inhibitors as anticancer agents in the past decade

Xiaoxia Liang, Qiang Wu, Shangxian Luan, Zhongqiong Yin, Changliang He, Lizi Yin, Yuanfeng Zou, Zhixiang Yuan, Lixia Li, Xu Song, Min He, Cheng Lv and Wei Zhang

European Journal of Medicinal Chemistry, 2019, 171, 129
DOI: 10.1016/j.ejmech.2019.03.034

Antiviral Compounds from Codiaeum peltatum Targeted by a Multi-informative Molecular Networks Approach

Florent Olivon, Simon Remy, Gwendal Grelier, Cécile Apel, Cécilia Eydoux, Jean-Claude Guillemot, Johan Neyts, Leen Delang, David Touboul, Fanny Roussi and Marc Litaudon

J. Nat. Prod., 2019, 82, 330
DOI: 10.1021/acs.jnatprod.8b00800

ChemInform Abstract: Neogenkwanines A—H: Daphnane‐Type Diterpenes Containing 4,7 or 4,6‐Ether Groups from the Flower Bud of Daphne genkwa.

Ling‐Zhi Li, Shao‐Jiang Song, Pin‐Yi Gao, Fei‐Fei Li, Li‐Hui Wang, Qing‐Bo Liu, Xiao‐Xiao Huang, Dan‐Qi Li and Yu Sun

ChemInform, 2015, 46
DOI: 10.1002/chin.201524220

Daphnane Diterpenoids from Daphne retusa with Antiadipogenic Activity: Concurrent Suppression of Lipid Biosynthesis and Enhancement of Metabolic Pathways

Xiu-Qing Song, Yue Guo, Xin Wang, Qin-Qin Song and Yao-Yue Fan

J. Nat. Prod., 2025, 88, 1514
DOI: 10.1021/acs.jnatprod.5c00390

Modular total syntheses of thymifodioic/incanic acids

Sergio J. Álvarez-Méndez, J. Roberto Saad, Carlos E. Tonn, Víctor S. Martín and Celina García

Arabian Journal of Chemistry, 2019, 12, 3764
DOI: 10.1016/j.arabjc.2016.01.008

Isolation, Structural Elucidation, and Anti-HIV Activity of Daphnane Diterpenoids from Daphne odora

Kouharu Otsuki, Wei Li, Kasumi Miura, Yoshihisa Asada, Li Huang, Chin-Ho Chen, Kuo-Hsiung Lee and Kazuo Koike

J. Nat. Prod., 2020, 83, 3270
DOI: 10.1021/acs.jnatprod.0c00540