Development of coinage metal nanoclusters as antimicrobials to combat bacterial infections

Dan Li, Beena Kumari, Jessa Marie Makabenta, Bailong Tao, Kun Qian, Xifan Mei and Vincent M. Rotello

J. Mater. Chem. B, 2020, 8, 9466
DOI: 10.1039/D0TB00549E

Radiolabelling of nanomaterials for medical imaging and therapy

Juan Pellico, Peter J. Gawne and Rafael T. M. de Rosales

Chem. Soc. Rev., 2021, 50, 3355
DOI: 10.1039/D0CS00384K

177Lu-labeled carbon nanospheres: a new entry in the field of targeted radionanomedicine

Drishty Satpati, Ashis Satpati, Yugandhara Pamale, Chandan Kumar, Rohit Sharma, Haladhar Deb Sarma and Sharmila Banerjee

RSC Adv., 2016, 6, 50761
DOI: 10.1039/C5RA25502C

Optimal size and PEG coating of gold nanoparticles for prolonged blood circulation: a statistical analysis of published data

Dmitry Nevozhay, Ronald Rauch, Zhongya Wang and Konstantin V. Sokolov

Nanoscale Adv., 2025, 7, 722
DOI: 10.1039/D4NA00782D

Biodistribution studies of ultrasmall silicon nanoparticles and carbon dots in experimental rats and tumor mice

Nadia Licciardello, Sebastian Hunoldt, Ralf Bergmann, Garima Singh, Constantin Mamat, Angélique Faramus, John L. Z. Ddungu, Simone Silvestrini, Michele Maggini, Luisa De Cola and Holger Stephan

Nanoscale, 2018, 10, 9880
DOI: 10.1039/C8NR01063C

Peptide and protein modified metal clusters for cancer diagnostics

Dongdong Su, Liang Gao, Fuping Gao, Xiangchun Zhang and Xueyun Gao

Chem. Sci., 2020, 11, 5614
DOI: 10.1039/D0SC01201G

CC Chemokine Receptor 2-Targeting Copper Nanoparticles for Positron Emission Tomography-Guided Delivery of Gemcitabine for Pancreatic Ductal Adenocarcinoma

Xiaohui Zhang, Lisa Detering, Deborah Sultan, Hannah Luehmann, Lin Li, Gyu Seong Heo, Xiuli Zhang, Lanlan Lou, Patrick M. Grierson, Suellen Greco, Marianna Ruzinova, Richard Laforest, Farrokh Dehdashti, Kian-Huat Lim and Yongjian Liu

ACS Nano, 2021, 15, 1186
DOI: 10.1021/acsnano.0c08185

Generation-6 hydroxyl PAMAM dendrimers improve CNS penetration from intravenous administration in a large animal brain injury model

Fan Zhang, J. Trent Magruder, Yi-An Lin, Todd C. Crawford, Joshua C. Grimm, Christopher M. Sciortino, Mary Ann Wilson, Mary E. Blue, Sujatha Kannan, Michael V. Johnston, William A. Baumgartner and Rangaramanujam M. Kannan

Journal of Controlled Release, 2017, 249, 173
DOI: 10.1016/j.jconrel.2017.01.032

64Cu radiolabeled nanomaterials for positron emission tomography (PET) imaging

Xueqian Chen, Wenchao Niu, Zhongying Du, Yong Zhang, Dongdong Su and Xueyun Gao

Chinese Chemical Letters, 2022, 33, 3349
DOI: 10.1016/j.cclet.2022.02.070

64Cu-Doped PdCu@Au Tripods: A Multifunctional Nanomaterial for Positron Emission Tomography and Image-Guided Photothermal Cancer Treatment

Bo Pang, Yongfeng Zhao, Hannah Luehmann, Xuan Yang, Lisa Detering, Meng You, Chao Zhang, Lei Zhang, Zhi-Yuan Li, Qiushi Ren, Yongjian Liu and Younan Xia

ACS Nano, 2016, 10, 3121
DOI: 10.1021/acsnano.5b07968

Bioimaging guided pharmaceutical evaluations of nanomedicines for clinical translations

Ruslan G. Tuguntaev, Abid Hussain, Chenxing Fu, Haoting Chen, Ying Tao, Yan Huang, Lu Liu, Xing-Jie Liang and Weisheng Guo

J Nanobiotechnol, 2022, 20
DOI: 10.1186/s12951-022-01451-4

Chemokine Receptor 2 Targeted Gold Nanocluster Imaging Triple Negative Breast Cancer with Positron Emission Tomography

Yongfeng Zhao, Meng You, Lisa Detering, Deborah Sultan, Hannah Luehmann and Yongjian Liu

Part & Part Syst Charact, 2021, 38
DOI: 10.1002/ppsc.202000287

Inherently PET/CT Dual Modality Imaging Lipid Nanocapsules for Early Detection of Orthotopic Lung Tumors

Pengju Cai, Dongdong Su, Wenjiang Yang, Zhesheng He, Chunyu Zhang, Hui Liu, Zhibo Liu, Xiangchun Zhang, Liang Gao, Yu Liu, Huaidong Jiang, Fuping Gao and Xueyun Gao

ACS Appl. Bio Mater., 2020, 3, 611
DOI: 10.1021/acsabm.9b00993

Advances in Gold Nanoparticles: Synthesis, Functionalization Strategies, and Theranostic Applications in Cancer

Mansi Damani, Mrunal Jadhav, Rashmi Joshi, Bheeshma Pratap Singh, Munira M. Momin, Raghumani Singh Ningthoujam and Tabassum Khan

Crit Rev Ther Drug Carrier Syst, 2024, 41, 1
DOI: 10.1615/CritRevTherDrugCarrierSyst.2024046712

Clearance Pathways and Tumor Targeting of Imaging Nanoparticles

Mengxiao Yu and Jie Zheng

ACS Nano, 2015, 9, 6655
DOI: 10.1021/acsnano.5b01320

Green Synthesis of Gold Nanoparticles Using Plant Extracts as Beneficial Prospect for Cancer Theranostics

Kaushik Kumar Bharadwaj, Bijuli Rabha, Siddhartha Pati, Tanmay Sarkar, Bhabesh Kumar Choudhury, Arpita Barman, Dorothy Bhattacharjya, Ankit Srivastava, Debabrat Baishya, Hisham Atan Edinur, Zulhisyam Abdul Kari and Noor Haslina Mohd Noor

Molecules, 2021, 26, 6389
DOI: 10.3390/molecules26216389

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

Leila Farzin, Shahab Sheibani, Mohammad Esmaeil Moassesi and Mojtaba Shamsipur

J Biomedical Materials Res, 2019, 107, 251
DOI: 10.1002/jbm.a.36550

Light‐Emitting Agents for Noninvasive Assessment of Kidney Function

Jiaguo Huang and Norbert Gretz

ChemistryOpen, 2017, 6, 456
DOI: 10.1002/open.201700065

Serum Protein Adsorption and Excretion Pathways of Metal Nanoparticles

Rodrigo D Vinluan and Jie Zheng

Nanomedicine (Lond.), 2015, 10, 2781
DOI: 10.2217/nnm.15.97

Ultrasmall noble metal nanoparticles: Breakthroughs and biomedical implications

Xingya Jiang, Bujie Du, Yingyu Huang and Jie Zheng

Nano Today, 2018, 21, 106
DOI: 10.1016/j.nantod.2018.06.006

Gold nanoparticles meet medical radionuclides

Noami Daems, Carine Michiels, Stéphane Lucas, Sarah Baatout and An Aerts

Nuclear Medicine and Biology, 2021, 100-101, 61
DOI: 10.1016/j.nucmedbio.2021.06.001

Facile Synthesis of 64Cu‐Doped Au Nanocages for Positron Emission Tomography Imaging

Miaoxin Yang, Da Huo, Kyle D. Gilroy, Xiaojun Sun, Deborah Sultan, Hannah Luehmann, Lisa Detering, Shunqiang Li, Dong Qin, Yongjian Liu and Younan Xia

ChemNanoMat, 2017, 3, 44
DOI: 10.1002/cnma.201600281

In Vivo Behavior of Ultrasmall Spherical Nucleic Acids

Cassandra E. Callmann, Matthew K. Vasher, Anindita Das, Caroline D. Kusmierz and Chad A. Mirkin

Small, 2023, 19
DOI: 10.1002/smll.202300097

Recent Development of Gold Nanoparticles as Contrast Agents for Cancer Diagnosis

Dong Luo, Xinning Wang, Clemens Burda and James P. Basilion

Cancers, 2021, 13, 1825
DOI: 10.3390/cancers13081825

Radiolabeling of Gold Nanocages for Potential Applications in Tracking, Diagnosis, and Image‐Guided Therapy

Jichuan Qiu, Yongjian Liu and Younan Xia

Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202002031

Gold nanoparticles for cancer theranostics — A brief update

Ning Zhao, Yongxu Pan, Zhen Cheng and Hongguang Liu

J. Innov. Opt. Health Sci., 2016, 09, 1630004
DOI: 10.1142/S1793545816300044

Innate Immune Invisible Ultrasmall Gold Nanoparticles—Framework for Synthesis and Evaluation

Geyunjian Harry Zhu, Mohammad Azharuddin, Rakibul Islam, Hassan Rahmoune, Suryyani Deb, Upasona Kanji, Jyotirmoy Das, Johannes Osterrieth, Parminder Aulakh, Hashi Ibrahim-Hashi, Raghav Manchanda, Per H. Nilsson, Tom Eirik Mollnes, Maitreyee Bhattacharyya, Mohammad M. Islam, Jorma Hinkula, Nigel K. H. Slater and Hirak K. Patra

ACS Appl. Mater. Interfaces, 2021, 13, 23410
DOI: 10.1021/acsami.1c02834

Nanoparticles as Theranostic Vehicles in Experimental and Clinical Applications—Focus on Prostate and Breast Cancer

Jörgen Elgqvist

IJMS, 2017, 18, 1102
DOI: 10.3390/ijms18051102

Polymeric Nanostructures for Imaging and Therapy

Mahmoud Elsabahy, Gyu Seong Heo, Soon-Mi Lim, Guorong Sun and Karen L. Wooley

Chem. Rev., 2015, 115, 10967
DOI: 10.1021/acs.chemrev.5b00135

Makine Öğrenmesi ile Hedefe Yönelik Nanoterapötiklerin Üretim Parametrelerinin Optimizasyonu

Naim KARASEKRETER, Şeyda GÜNDÜZ, Sadık KAĞA and Süleyman YAMAN

European Journal of Science and Technology, 2022
DOI: 10.31590/ejosat.1084311

Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics

Shreya Goel, Christopher G. England, Feng Chen and Weibo Cai

Advanced Drug Delivery Reviews, 2017, 113, 157
DOI: 10.1016/j.addr.2016.08.001

Liposomal delivery of CRISPR/Cas9

Shuai Zhen and Xu Li

Cancer Gene Ther, 2020, 27, 515
DOI: 10.1038/s41417-019-0141-7

Advances of gold nanoclusters for bioimaging

Cheng Zhang, Xiaobing Gao, Wenrui Chen, Meng He, Yao Yu, Guanbin Gao and Taolei Sun

iScience, 2022, 25, 105022
DOI: 10.1016/j.isci.2022.105022

Underlying mechanisms of gold nanoalloys stabilization

Lucas B. Pena, Lucas R. Da Silva, Juarez L. F. Da Silva and Breno R. L. Galvão

The Journal of Chemical Physics, 2023, 159
DOI: 10.1063/5.0180906

In situ radiochemical doping of functionalized inorganic nanoplatforms for theranostic applications: a paradigm shift in nanooncology

Sanchita Ghosh, Yutong Liang, Weibo Cai and Rubel Chakravarty

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03472-1

Gold Nanomaterials at Work in Biomedicine

Xuan Yang, Miaoxin Yang, Bo Pang, Madeline Vara and Younan Xia

Chem. Rev., 2015, 115, 10410
DOI: 10.1021/acs.chemrev.5b00193

Noninvasive Imaging of CCR2+ Cells in Ischemia-Reperfusion Injury After Lung Transplantation

Y. Liu, W. Li, H.P. Luehmann, Y. Zhao, L. Detering, D.H. Sultan, H.-M. Hsiao, A.S. Krupnick, A.E. Gelman, C. Combadiere, R.J. Gropler, S.L. Brody and D. Kreisel

American Journal of Transplantation, 2016, 16, 3016
DOI: 10.1111/ajt.13907

Nanomedicine for Cancer Diagnosis and therapy: advancement, Success and structure–activity Relationship

Ketki Bhise, Samaresh Sau, Hashem Alsaab, Sushil Kumar Kashaw, Rakesh Kumar Tekade and Arun K Iyer

Ther. Deliv., 2017, 8, 1003
DOI: 10.4155/tde-2017-0062

Boron agents for neutron capture therapy

Kuan Hu, Zhimin Yang, Lingling Zhang, Lin Xie, Lu Wang, Hao Xu, Lee Josephson, Steven H. Liang and Ming-Rong Zhang

Coordination Chemistry Reviews, 2020, 405, 213139
DOI: 10.1016/j.ccr.2019.213139

Efficacy of 15 nm Gold Nanoparticles for Image-Guided Gliosarcoma Radiotherapy

Elette Engels, Michael Lerch, Stéphanie Corde and Moeava Tehei

JNT, 2023, 4, 480
DOI: 10.3390/jnt4040021

Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation

Gyu Seong Heo, Yongfeng Zhao, Deborah Sultan, Xiaohui Zhang, Lisa Detering, Hannah P. Luehmann, Xiangyu Zhang, Richen Li, Ankur Choksi, Savannah Sharp, Sidney Levingston, Tina Primeau, David E. Reichert, Guorong Sun, Babak Razani, Shunqiang Li, Katherine N. Weilbaecher, Farrokh Dehdashti, Karen L. Wooley and Yongjian Liu

ACS Appl. Mater. Interfaces, 2019, 11, 19669
DOI: 10.1021/acsami.8b22752

Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance

Chuanqi Peng, Yingyu Huang and Jie Zheng

Journal of Controlled Release, 2020, 322, 64
DOI: 10.1016/j.jconrel.2020.03.020

Ultrasmall-in-Nano: Why Size Matters

Ryan D. Mellor and Ijeoma F. Uchegbu

Nanomaterials, 2022, 12, 2476
DOI: 10.3390/nano12142476

Gold nanoclusters: An ultrasmall platform for multifaceted applications

Sonia, Komal, Shrikant Kukreti and Mahima Kaushik

Talanta, 2021, 234, 122623
DOI: 10.1016/j.talanta.2021.122623

Gold Nanoparticles Doped with 199Au Atoms and Their Use for Targeted Cancer Imaging by SPECT

Yongfeng Zhao, Bo Pang, Hannah Luehmann, Lisa Detering, Xuan Yang, Deborah Sultan, Scott Harpstrite, Vijay Sharma, Cathy S. Cutler, Younan Xia and Yongjian Liu

Adv Healthcare Materials, 2016, 5, 928
DOI: 10.1002/adhm.201500992

Gold Nanoclusters Doped with64Cu for CXCR4 Positron Emission Tomography Imaging of Breast Cancer and Metastasis

Yongfeng Zhao, Lisa Detering, Deborah Sultan, Matthew L Cooper, Meng You, Sangho Cho, Stephanie L. Meier, Hannah Luehmann, Guorong Sun, Michael Rettig, Farrokh Dehdashti, Karen L. Wooley, John F. DiPersio and Yongjian Liu

ACS Nano, 2016, 10, 5959
DOI: 10.1021/acsnano.6b01326

Cation Exchange Protocols to Radiolabel Aqueous Stabilized ZnS, ZnSe, and CuFeS2 Nanocrystals with 64Cu for Dual Radio‐ and Photo‐Thermal Therapy

Tommaso Avellini, Nisarg Soni, Niccolò Silvestri, Sergio Fiorito, Francesco De Donato, Claudia De Mei, Martin Walther, Marco Cassani, Sandeep Ghosh, Liberato Manna, Holger Stephan and Teresa Pellegrino

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.202002362

Multimodal radiolabeled gold nanoparticle molecular probes: synthesis, imaging, and applications

Qinyue Gao and Fei Chen

J Radioanal Nucl Chem, 2023, 332, 1625
DOI: 10.1007/s10967-023-08895-4

Towards clinically translatable in vivo nanodiagnostics

Seung-min Park, Amin Aalipour, Ophir Vermesh, Jung Ho Yu and Sanjiv S. Gambhir

Nat Rev Mater, 2017, 2
DOI: 10.1038/natrevmats.2017.14

Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications

Kristof Zarschler, Louise Rocks, Nadia Licciardello, Luca Boselli, Ester Polo, Karina Pombo Garcia, Luisa De Cola, Holger Stephan and Kenneth A. Dawson

Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12, 1663
DOI: 10.1016/j.nano.2016.02.019

Focused Ultrasound Enabled Trans‐Blood Brain Barrier Delivery of Gold Nanoclusters: Effect of Surface Charges and Quantification Using Positron Emission Tomography

Deborah Sultan, Dezhuang Ye, Gyu Seong Heo, Xiaohui Zhang, Hannah Luehmann, Yimei Yue, Lisa Detering, Sergey Komarov, Sara Taylor, Yuan‐Chuan Tai, Joshua B. Rubin, Hong Chen and Yongjian Liu

Small, 2018, 14
DOI: 10.1002/smll.201703115

Probing the biological obstacles of nanomedicine with gold nanoparticles

Bin Li and Lucas A. Lane

WIREs Nanomed Nanobiotechnol, 2019, 11
DOI: 10.1002/wnan.1542

Nanoparticles and Radioisotopes: A Long Story in a Nutshell

Giulia Poletto, Laura Evangelista, Francesca Venturini, Fabiana Gramegna, Flavio Seno, Stefano Moro, Roberto Vettor, Nicola Realdon and Diego Cecchin

Pharmaceutics, 2022, 14, 2024
DOI: 10.3390/pharmaceutics14102024

Mouse Positron Emission Tomography Study of the Biodistribution of Gold Nanoparticles with Different Surface Coatings Using Embedded Copper-64

Anders F. Frellsen, Anders E. Hansen, Rasmus I. Jølck, Paul J. Kempen, Gregory W. Severin, Palle H. Rasmussen, Andreas Kjær, Andreas T. I. Jensen and Thomas L. Andresen

ACS Nano, 2016, 10, 9887
DOI: 10.1021/acsnano.6b03144

Radiolabeled theranostics: magnetic and gold nanoparticles

Saeideh Same, Ayuob Aghanejad, Sattar Akbari Nakhjavani, Jaleh Barar and Yadollah Omidi

Bioimpacts, 2016, 6, 169
DOI: 10.15171/bi.2016.23

Multiscale Bioresponses of Metal Nanoclusters

Yujia Shi, Zhennan Wu, Manlin Qi, Chengyu Liu, Weinan Dong, Wenyue Sun, Xue Wang, Feng Jiang, Yuan Zhong, Di Nan, Yu Zhang, Chunyan Li, Lin Wang and Xue Bai

Advanced Materials, 2024, 36
DOI: 10.1002/adma.202310529

Therapeutic Pretargeting with Gold Nanoparticles as Drug Candidates for Boron Neutron Capture Therapy

Irene V. J. Feiner, Krishna R. Pulagam, Vanessa Gómez‐Vallejo, Kepa Zamacola, Zuriñe Baz, María M. Caffarel, Charles H. Lawrie, Ane Ruiz‐de‐Angulo, Mónica Carril and Jordi Llop

Part & Part Syst Charact, 2020, 37
DOI: 10.1002/ppsc.202000200

A multi-functional polymeric carrier for simultaneous positron emission tomography imaging and combination therapy

Jingjing Sun, Lingyi Sun, Jianchun Li, Jieni Xu, Zhuoya Wan, Zubin Ouyang, Lei Liang, Song Li and Dexing Zeng

Acta Biomaterialia, 2018, 75, 312
DOI: 10.1016/j.actbio.2018.06.010

Focused ultrasound combined with microbubble-mediated intranasal delivery of gold nanoclusters to the brain

Dezhuang Ye, Xiaohui Zhang, Yimei Yue, Ramesh Raliya, Pratim Biswas, Sara Taylor, Yuan-chuan Tai, Joshua B. Rubin, Yongjian Liu and Hong Chen

Journal of Controlled Release, 2018, 286, 145
DOI: 10.1016/j.jconrel.2018.07.020

Core–shell structured gold nanoparticles as carrier for 166Dy/166Ho in vivo generator

Runze Wang, Bernard Ponsard, Hubert Wolterbeek and Antonia Denkova

EJNMMI radiopharm. chem., 2022, 7
DOI: 10.1186/s41181-022-00170-3

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

Jianxian Ge, Qianyi Zhang, Jianfeng Zeng, Zi Gu and Mingyuan Gao

Biomaterials, 2020, 228, 119553
DOI: 10.1016/j.biomaterials.2019.119553

Gold nanoparticles in combinatorial cancer therapy strategies

Jaber Beik, Maziar Khateri, Zohreh Khosravi, S. Kamran Kamrava, Siavash Kooranifar, Habib Ghaznavi and Ali Shakeri-Zadeh

Coordination Chemistry Reviews, 2019, 387, 299
DOI: 10.1016/j.ccr.2019.02.025

Metal Nanoclusters for Cancer Imaging and Treatment

Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie and Xun Yuan

Adv Funct Materials, 2025
DOI: 10.1002/adfm.202507924