Potential prebiotic activity of Tenebrio molitor insect flour using an optimized in vitro gut microbiota model

Nelson Mota de Carvalho, Francisco Teixeira, Sara Silva, Ana Raquel Madureira and Manuela Estevez Pintado

Food Funct., 2019, 10, 3909
DOI: 10.1039/C8FO01536H

Selenium-containing polysaccharides from Ziyang green tea ameliorate high-fructose diet induced insulin resistance and hepatic oxidative stress in mice

Daoyuan Ren, Yuanyuan Hu, Yiyang Luo and Xingbin Yang

Food Funct., 2015, 6, 3342
DOI: 10.1039/C5FO00557D

In vitro fermentation of mulberry fruit polysaccharides by human fecal inocula and impact on microbiota

Chun Chen, Qiang Huang, Xiong Fu and Rui Hai Liu

Food Funct., 2016, 7, 4637
DOI: 10.1039/C6FO01248E

Mucilage as a functional food hydrocolloid: ongoing and potential applications in prebiotics and nutraceuticals

Iman A. A. Kassem, Tolulope Joshua Ashaolu, Rabab Kamel, Nermeen A. Elkasabgy, Sherif M. Afifi and Mohamed A. Farag

Food Funct., 2021, 12, 4738
DOI: 10.1039/D1FO00438G

Gum odina: an emerging gut modulating approach in colorectal cancer prevention

Debmalya Mitra, Abhishek Basu, Bhaskar Das, Aditya Kr. Jena, Arnab De, Mousumi Das, Sudin Bhattacharya and Amalesh Samanta

RSC Adv., 2017, 7, 29129
DOI: 10.1039/C7RA04077F

Residues from grapevine and wine production as feedstock for a biorefinery

María del Mar Contreras, Juan Miguel Romero-García, Juan Carlos López-Linares, Inmaculada Romero and Eulogio Castro

Food and Bioproducts Processing, 2022, 134, 56
DOI: 10.1016/j.fbp.2022.05.005

Impact of Cashew (Anacardium occidentale L.) by-Product on Composition and Metabolic Activity of Human Colonic Microbiota In Vitro Indicates Prebiotic Properties

Francisca Nayara Dantas Duarte Menezes, Érika Tayse da Cruz Almeida, Arthur Rodrigo da Silva Vieira, Jailane de Souza Aquino, Marcos dos Santos Lima, Marciane Magnani and Evandro Leite de Souza

Curr Microbiol, 2021, 78, 2264
DOI: 10.1007/s00284-021-02502-z

Impact of the source of fermentable carbohydrate on SCFA production by human gut microbiota in vitro - a systematic scoping review and secondary analysis

Hannah C. Harris, Douglas J. Morrison and Christine A. Edwards

Critical Reviews in Food Science and Nutrition, 2021, 61, 3892
DOI: 10.1080/10408398.2020.1809991

Therapeutic effects of Aloe spp. in traditional and modern medicine: A review

Maryam Akaberi, Zahra Sobhani, Behjat Javadi, Amirhossein Sahebkar and Seyed Ahmad Emami

Biomedicine & Pharmacotherapy, 2016, 84, 759
DOI: 10.1016/j.biopha.2016.09.096

Acemannan and Fructans from Aloe vera (Aloe barbadensis Miller) Plants as Novel Prebiotics

Maria Paz Quezada, Carlos Salinas, Martin Gotteland and Liliana Cardemil

J. Agric. Food Chem., 2017, 65, 10029
DOI: 10.1021/acs.jafc.7b04100

In vitro fecal fermentation properties of polysaccharides from Tremella fuciformis and related modulation effects on gut microbiota

Ding-Tao Wu, Ling-Yan An, Wen Liu, Yi-Chen Hu, Sheng-Peng Wang and Liang Zou

Food Research International, 2022, 156, 111185
DOI: 10.1016/j.foodres.2022.111185

Study on fecal fermentation characteristics of aloe polysaccharides in vitro and their predictive modeling

Chang Liu, Peng Du, Yuliang Cheng, Yahui Guo, Bin Hu, Weirong Yao, Xuan Zhu and He Qian

Carbohydrate Polymers, 2021, 256, 117571
DOI: 10.1016/j.carbpol.2020.117571

Ingredients from integral valorization of Isabel grape to formulate goat yogurt with stimulatory effects on probiotics and beneficial impacts on human colonic microbiota in vitro

Francyeli Araújo Silva, Rita de Cássia Ramos do Egypto Queiroga, Evandro Leite de Souza, Glenise Bierhalz Voss, Maria Manuela Estevez Pintado and Margarida Angélica da Silva Vasconcelos

Food Science and Human Wellness, 2023, 12, 1331
DOI: 10.1016/j.fshw.2022.10.034

In vitro Fermentation of Polysaccharides from Aloe vera and the Evaluation of Antioxidant Activity and Production of Short Chain Fatty Acids

Antonio Tornero-Martínez, Rubén Cruz-Ortiz, María Eugenia Jaramillo-Flores, Perla Osorio-Díaz, Sandra Victoria Ávila-Reyes, Guadalupe Monserrat Alvarado-Jasso and Rosalva Mora-Escobedo

Molecules, 2019, 24, 3605
DOI: 10.3390/molecules24193605

Randomized clinical trial: Effects of Aloe barbadensis Mill. extract on symptoms, fecal microbiota and fecal metabolite profiles in patients with irritable bowel syndrome

Bani Ahluwalia, Maria K. Magnusson, Lena Böhn, Stine Störsrud, Fredrik Larsson, Otto Savolainen, Alastair Ross, Magnus Simrén and Lena Öhman

Neurogastroenterology Motil, 2020, 32
DOI: 10.1111/nmo.13860

Manufacture and evaluation of xylooligosaccharides from corn stover as emerging prebiotic candidates for human health

Cristian-Teodor Buruiana, Belén Gómez, Camelia Vizireanu and Gil Garrote

LWT, 2017, 77, 449
DOI: 10.1016/j.lwt.2016.11.083

Anti-hypertensive and cardioprotective activities of traditional Chinese medicine-derived polysaccharides: A review

Miaotian Xie, Weili Tao, Fengjia Wu, Kunlin Wu, Xiujie Huang, Gensong Ling, Chuanyi Zhao, Qian Lv, Qiongjin Wang, Xianhuan Zhou, Ying Chen, Qin Yuan and Yicun Chen

International Journal of Biological Macromolecules, 2021, 185, 917
DOI: 10.1016/j.ijbiomac.2021.07.008

Unraveling the role of medicinal plants and Gut microbiota in colon cancer: Towards microbiota- based strategies for prevention and treatment

Arumugam Vignesh, Thomas Cheeran Amal, Subramaniam Selvakumar and Krishnan Vasanth

Health Sciences Review, 2023, 9, 100115
DOI: 10.1016/j.hsr.2023.100115

In vitro fermentability of a broad range of natural ingredients by fecal microbiota from lean and obese individuals: potential health benefits

Andreu Gual-Grau, Maria Guirro, Anna Crescenti, Noemí Boqué and Lluís Arola

International Journal of Food Sciences and Nutrition, 2022, 73, 195
DOI: 10.1080/09637486.2021.1954144

Bioactivity and Bioaccessibility of Bioactive Compounds in Gastrointestinal Digestion of Tomato Bagasse Extracts

Marta Coelho, Carla Oliveira, Ezequiel R. Coscueta, João Fernandes, Ricardo N. Pereira, José A. Teixeira, António Sebastião Rodrigues and Manuela E. Pintado

Foods, 2022, 11, 1064
DOI: 10.3390/foods11071064

Anthraquinones and Aloe Vera Extracts as Potential Modulators of Inflammaging Mechanisms: A Translational Approach from Autoimmune to Onco-Hematological Diseases

Raffaele Cordiano, Santino Caserta, Paola Lucia Minciullo, Alessandro Allegra and Sebastiano Gangemi

Molecules, 2025, 30, 1251
DOI: 10.3390/molecules30061251

Regulating Effects of Three Polysaccharides on Gut Microbiota in Felines and Canines: Insights from In Vitro Digestion, Fecal Fermentation, and Lactic Acid Bacterial Fermentation

Huasong Bai, Tong Liu, Hengyan Wang, Yunliang Li and Zhanzhong Wang

J. Agric. Food Chem., 2025, 73, 9618
DOI: 10.1021/acs.jafc.4c12847

Evaluation of Prebiotic and Antimicrobial Properties of Natural Extracts

Ms. Naina Bhanjer, Ms. Prachi Bhatia and Dr. Sejal Rathod

IJSRST, 2021, 390
DOI: 10.32628/IJSRST218556

Reciprocal interaction between gut microbiota and aloe-emodin results in altered microbiome composition and metabolism of aloe-emodin

Ruhi Walia, Saumya Ray Chaudhuri and Priyankar Dey

Food Bioscience, 2025, 70, 107061
DOI: 10.1016/j.fbio.2025.107061

The Renaissance of Plant Mucilage in Health Promotion and Industrial Applications: A Review

Katarzyna Dybka-Stępień, Anna Otlewska, Patrycja Góźdź and Małgorzata Piotrowska

Nutrients, 2021, 13, 3354
DOI: 10.3390/nu13103354

Randomized double blind crossover trial of Aloe vera , Cnidoscolus chayamansa and placebo for reducing hyperglycemia in women with early metabolic syndrome

Lilia Cárdenas-Ibarra, Jesús Z. Villarreal-Pérez, J. Carlos Lira-Castillo and Aram Nava-Alemán

Clinical Nutrition Experimental, 2017, 14, 1
DOI: 10.1016/j.yclnex.2017.05.003

Efficacy of a Synbiotic Containing Lactobacillus paracasei DKGF1 and Opuntia humifusa in Elderly Patients with Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

Joo Hyun Oh, Yeon Sil Jang, Danbee Kang, Hong Seog Kim, Eui-Joong Kim, So-Young Park, Cheol-Hyun Kim, Yang Won Min and Dong Kyung Chang

Gut and Liver, 2023, 17, 100
DOI: 10.5009/gnl210478

Chinese patent medicine shouhui tongbian capsule attenuated loperamide-induced constipation through modulating the gut microbiota in rat

Qian Lin, Man Liu, Famous Erhunmwunsee, Bing Li, Yanfang Mou, Sen Wang, Guimin Zhang and Jun Tian

Journal of Ethnopharmacology, 2022, 298, 115575
DOI: 10.1016/j.jep.2022.115575

Advances in the in vitro digestion and fermentation of polysaccharides

Yuxi Guo, Xuefeng Chen, Pin Gong, Fuxin Chen, Dandan Cui and Mengrao Wang

Int J of Food Sci Tech, 2021, 56, 4970
DOI: 10.1111/ijfs.15308

An in vitro fermentation study on the effects of Dendrobium officinale polysaccharides on human intestinal microbiota from fecal microbiota transplantation donors

Yousi Fu, Junnan Zhang, Kainan Chen, Chuanxing Xiao, Lina Fan, Bangzhou Zhang, Jianlin Ren and Baishan Fang

Journal of Functional Foods, 2019, 53, 44
DOI: 10.1016/j.jff.2018.12.005

Unveiling the potential of linseed mucilage, its health benefits, and applications in food packaging

Monika Chand, Rajni Chopra, Binanshu Talwar, Snigdha Homroy, Priyanka Kumari Singh, Aishwarya Dhiman and Abdul Wahid Payyunni

Front. Nutr., 2024, 11
DOI: 10.3389/fnut.2024.1334247

Carbohydrate‐Rich Fraction of Aloe vera (L.) Burm.f. Extract Mitigates Bone Loss and Improves Metabolic Disturbance in Estrogen‐Deficient Rats

Panan Suntornsaratoon, Wajathip Bulanawichit, Wikanda Chimlek, Wanwipa Saeten, Waraporn Sorndech, Wiriyaporn Sumsakul, Suchinda Malaivijitnond, Vitoon Saengsirisuwan, Nateetip Krishnamra and Narattaphol Charoenphandhu

Pharmacology Res & Perspec, 2025, 13
DOI: 10.1002/prp2.70148

Pharmacological Update Properties of Aloe Vera and its Major Active Constituents

Marta Sánchez, Elena González-Burgos, Irene Iglesias and M. Pilar Gómez-Serranillos

Molecules, 2020, 25, 1324
DOI: 10.3390/molecules25061324

Development and Morphological/Microstructural Characterization of a Novel Synergic Synbiotic Co‐Encapsulated Lactobacillus spp. Consortium and Kale Powder

Monica Villanueva‐Castañeda, Mayra Antunez‐Mojica, Daniel Tapia‐Maruri, Ollin Celeste Martínez Ramírez, Raúl Dávila Delgado and América Ivette Barrera‐Molina

Food Science & Nutrition, 2025, 13
DOI: 10.1002/fsn3.71314

Understanding the impact of chia seed mucilage on human gut microbiota by using the dynamic gastrointestinal model simgi®

Alba Tamargo, Carolina Cueva, Laura Laguna, M.Victoria Moreno-Arribas and Loreto A. Muñoz

Journal of Functional Foods, 2018, 50, 104
DOI: 10.1016/j.jff.2018.09.028

An Assessment of the Glyconutrient Ambrotose™ on Immunity, Gut Health, and Safety in Men and Women: A Placebo-Controlled, Double-Blind, Randomized Clinical Trial

Richard J. Bloomer, Matthew Butawan, Marie van der Merwe and Faith H. Keating

Nutrients, 2020, 12, 1751
DOI: 10.3390/nu12061751

Aloe Barbadensis Miller (Aloe Vera)

Sukhdeep Kaur and Kiran Bains

International Journal for Vitamin and Nutrition Research, 2024, 94, 308
DOI: 10.1024/0300-9831/a000797

Structural characterization and prebiotic potential of an acidic polysaccharide from Imperial Chrysanthemum

Chun-Yu Liu, Jie Meng, Jing-Yi Qiu, Xue-Qing Geng, Hui-Qing Sun and Zhen-Yuan Zhu

Natural Product Research, 2022, 36, 586
DOI: 10.1080/14786419.2020.1795657

Gut microbiota in phytopharmacology: A comprehensive overview of concepts, reciprocal interactions, biotransformations and mode of actions

Priyankar Dey

Pharmacological Research, 2019, 147, 104367
DOI: 10.1016/j.phrs.2019.104367

Functional improvement of synbiotic yogurt enriched with Lacticaseibacillus rhamnosus and aloe vera gel using the response surface method

Sadia Ahmed, Asia Noor, Muhammad Tariq and Arsalan Zaidi

Food Prod Process and Nutr, 2023, 5
DOI: 10.1186/s43014-023-00153-0

Aloe vera―An Extensive Review Focused on Recent Studies

Alessia Catalano, Jessica Ceramella, Domenico Iacopetta, Maria Marra, Filomena Conforti, Francesca R. Lupi, Domenico Gabriele, Fernanda Borges and Maria Stefania Sinicropi

Foods, 2024, 13, 2155
DOI: 10.3390/foods13132155

Aloe barbadensis Mill. extract improves symptoms in IBS patients with diarrhoea: post hoc analysis of two randomized double-blind controlled studies

Bani Ahluwalia, Maria K. Magnusson, Lena Böhn, Stine Störsrud, Fredrik Larsson, Lena Öhman and Magnus Simrén

Therap Adv Gastroenterol, 2021, 14
DOI: 10.1177/17562848211048133

In vitro fermentation of κ-carrageenan oligosaccharides by human gut microbiota and its inflammatory effect on HT29 cells

Yujiao Sun, Xiangyi Cui, Mengmeng Duan, Chunqing Ai, Shuang Song and Xuefeng Chen

Journal of Functional Foods, 2019, 59, 80
DOI: 10.1016/j.jff.2019.05.036

Food supplements and diet as treatment options in irritable bowel syndrome

Eirini Dimidi and Kevin Whelan

Neurogastroenterology Motil, 2020, 32
DOI: 10.1111/nmo.13951

In vitro digestion by saliva, simulated gastric and small intestinal juices and fermentation by human fecal microbiota of sulfated polysaccharides from Gracilaria rubra

Tong Di, Guijie Chen, Yi Sun, Shiyi Ou, Xiaoxiong Zeng and Hong Ye

Journal of Functional Foods, 2018, 40, 18
DOI: 10.1016/j.jff.2017.10.040

Aloe Vera Inhibits Protein Fibrillation: Mechanistic Biophysical Evaluation

Anu Jain and Nand Kishore

Langmuir, 2025, 41, 29688
DOI: 10.1021/acs.langmuir.5c03925

Aloe Vera Polysaccharides as Therapeutic Agents: Benefits Versus Side Effects in Biomedical Applications

Consuela Elena Matei, Anita Ioana Visan and Rodica Cristescu

Polysaccharides, 2025, 6, 36
DOI: 10.3390/polysaccharides6020036

Food carbohydrates in the gut: structural diversity, microbial utilization, and analytical strategies

HyunJi Lee, JaeHui Song, Bokyung Lee, Jaeho Cha and Hyeyoung Lee

Food Sci Biotechnol, 2024, 33, 2123
DOI: 10.1007/s10068-024-01648-3

Modulation of the Gut Microbiota by Tomato Flours Obtained after Conventional and Ohmic Heating Extraction and Its Prebiotic Properties

Marta C. Coelho, Célia Costa, Dalila Roupar, Sara Silva, A. Sebastião Rodrigues, José A. Teixeira and Manuela E. Pintado

Foods, 2023, 12, 1920
DOI: 10.3390/foods12091920

Vine shoots as new source for the manufacture of prebiotic oligosaccharides

Izaskun Dávila, Beatriz Gullón, José Luis Alonso, Jalel Labidi and Patricia Gullón

Carbohydrate Polymers, 2019, 207, 34
DOI: 10.1016/j.carbpol.2018.11.065

In Vitro Digestion and Gut Microbiota Fermentation of the Anticancer Marine Drug BG136: Stability and Biotransformation Investigation

Xintong Li, Shuying Xu, Baiyuan Chen, Pengcheng Gao, Youjing Lv, Qingsen Shang, Guangli Yu and Guoyun Li

Marine Drugs, 2025, 23, 156
DOI: 10.3390/md23040156

Bioaccessibility, changes in the antioxidant potential and colonic fermentation of date pits and apple bagasse flours obtained from co-products during simulated in vitro gastrointestinal digestion

Beatriz Gullon, Manuela E. Pintado, Xavier Barber, Juana Fernández-López, José A. Pérez-Álvarez and Manuel Viuda-Martos

Food Research International, 2015, 78, 169
DOI: 10.1016/j.foodres.2015.10.021

Aloe vera and its byproducts as sources of valuable bioactive compounds: Extraction, biological activities, and applications in various food industries

Emmanuel Ofosu Mensah, Parise Adadi, Richard Vincent Asase, Opoku Kelvin, Fatemeh Jalil Mozhdehi, Isaac Amoah and Dominic Agyei

PharmaNutrition, 2025, 31, 100436
DOI: 10.1016/j.phanu.2025.100436

Functional fractions of Astragalus polysaccharides as a potential prebiotic to alleviate ulcerative colitis

Zeqi Huo, Junxiang Li, Xiaofeng Li, Han Xiao, Yang Lin, Yuchan Ma, Jiaru Li, Hui Yang and Chunjiang Zhang

International Journal of Biological Macromolecules, 2024, 271, 132580
DOI: 10.1016/j.ijbiomac.2024.132580

The role of gut microbiota in disease management: Ayurvedic perspectives on metabolic diseases and health

Bhawana Jangra, Shreyanshi Kulshreshtha, Alok Goyal and Sanjay M. Jachak

Phytomedicine Plus, 2025, 5, 100731
DOI: 10.1016/j.phyplu.2025.100731

Cottage cheese enriched with lactobacilli encapsulated in alginate–chitosan microparticles forestalls perishability and augments probiotic activity

Sadia Ahmed, Tariq Muhammad and Arsalan Zaidi

J. Food Process. Preserv., 2021, 45
DOI: 10.1111/jfpp.15473

Xylooligosaccharides from steam-exploded barley straw: Structural features and assessment of bifidogenic properties

Cristina Álvarez, Alberto González, José Luis Alonso, Felicia Sáez, María José Negro and Beatriz Gullón

Food and Bioproducts Processing, 2020, 124, 131
DOI: 10.1016/j.fbp.2020.08.014

Aloe vera at the frontier of glycobiology and integrative medicine: Health implications of an ancient plant

Peter Pressman, Roger Clemens and A Wallace Hayes

SAGE Open Medicine, 2019, 7
DOI: 10.1177/2050312119875921

Modulation of Pro-inflammatory and Anti-inflammatory Cytokines in the Fat by an Aloe Gel-based Formula, QDMC, Is Correlated with Altered Gut Microbiota

Jinho An, Heetae Lee, Sungwon Lee, Youngcheon Song, Jiyeon Kim, Il Ho Park, Hyunseok Kong and Kyungjae Kim

Immune Netw, 2021, 21
DOI: 10.4110/in.2021.21.e15