A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity

Dik-Lung Ma, Lihua Lu, Sheng Lin, Bingyong He and Chung-Hang Leung

J. Mater. Chem. B, 2015, 3, 348
DOI: 10.1039/C4TB01569J

A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione

Ka-Ho Leung, Hong-Zhang He, Victor Pui-Yan Ma, Daniel Shiu-Hin Chan, Chung-Hang Leung and Dik-Lung Ma

Chem. Commun., 2013, 49, 771
DOI: 10.1039/C2CC37710A

A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ions based on the exonuclease III-mediated digestion of C–Ag+–C DNA

Modi Wang, Ka-Ho Leung, Sheng Lin, Daniel Shiu-Hin Chan, Chung-Hang Leung and Dik-Lung Ma

J. Mater. Chem. B, 2014, 2, 6467
DOI: 10.1039/C4TB01140F

Unravelling the binding affinity and selectivity of molybdenum(ii) phenanthroline complexes with DNA G-quadruplexes by using linear-scaling DFT studies. The important role of ancillary ligands

Iker Ortiz de Luzuriaga, Ángel Sánchez-González, Wojciech Synoradzki, Xabier Lopez and Adrià Gil

Phys. Chem. Chem. Phys., 2022, 24, 25918
DOI: 10.1039/D2CP02241A

Advancing environmental safety and public health: a comprehensive review of luminescent probes for radioactive element detection

Yang Pei, Lei Fang, Jiaqi Zhang, Zixun Wang, Linhao Zheng, Yuxuan Zhang, Jiayuan Zhu, Ziyu Wang, Chi Zhang and Jian-Bin Pan

Analyst, 2025, 150, 4252
DOI: 10.1039/D5AN00683J

Recent developments of nanoenzyme-based colorimetric sensors for heavy metal detection and the interaction mechanism

Zhengquan Yan, Hua Yuan, Qi Zhao, Lin Xing, Xiaoyu Zheng, Weiguo Wang, Yulei Zhao, Yang Yu, Lei Hu and Wenli Yao

Analyst, 2020, 145, 3173
DOI: 10.1039/D0AN00339E

A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

Ka-Ho Leung, Hong-Zhang He, Victor Pui-Yan Ma, Hui Yang, Daniel Shiu-Hin Chan, Chung-Hang Leung and Dik-Lung Ma

RSC Adv., 2013, 3, 1656
DOI: 10.1039/C2RA21996D

Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe

Ka-Ho Leung, Hong-Zhang He, Victor Pui-Yan Ma, Hai-Jing Zhong, Daniel Shiu-Hin Chan, Jun Zhou, Jean-Louis Mergny, Chung-Hang Leung and Dik-Lung Ma

Chem. Commun., 2013, 49, 5630
DOI: 10.1039/c3cc41129j

Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems

Jiangtao Ren, Tianshu Wang, Erkang Wang and Jin Wang

Analyst, 2015, 140, 2556
DOI: 10.1039/C4AN02282C

A label-free fluorescent peptide probe for sensitive and selective determination of copper and sulfide ions in aqueous systems

Yadan Zhang, Yunhui Cai, Yonghui He, Qinlu Lin, Jiali Ren, Dongsheng Cao and Lin Zhang

RSC Adv., 2021, 11, 7426
DOI: 10.1039/D0RA08788B

Label-free luminescent oligonucleotide-based probes

Dik-Lung Ma, Hong-Zhang He, Ka-Ho Leung, Hai-Jing Zhong, Daniel Shiu-Hin Chan and Chung-Hang Leung

Chem. Soc. Rev., 2013, 42, 3427
DOI: 10.1039/c2cs35472a

A G-quadruplex-based platform for the detection of Hg2+ ions using a luminescent iridium(iii) complex

Sheng Lin, Bingyong He, Daniel Shiu-Hin Chan, Philip Wai Hong Chan, Chung-Hang Leung and Dik-Lung Ma

RSC Adv., 2014, 4, 54826
DOI: 10.1039/C4RA11240G

Metalloenzyme-mimic innate G-quadruplex DNAzymes using directly coordinated metal ions as active centers

Yali Yu, Qingqing Zhang, Heng Gao, Chenxiao Yan, Xiong Zheng, Tong Yang, Xiaoshun Zhou and Yong Shao

Dalton Trans., 2020, 49, 13160
DOI: 10.1039/D0DT02871A

Design and characterization of a 2-(2’-hydroxyphenyl)benzimidazole-based Sr2+-selective fluorescent probe in organic and micellar solution systems†

Kazuhiro Akutsu-Suyama, Seiji Mori and Takayasu Hanashima

Photochem Photobiol Sci, 2019, 18, 2531
DOI: 10.1039/c9pp00275h

A novel chemosensor for sensitive and facile detection of strontium ions based on ion-imprinted hydrogels modified with guanosine derivatives

Yu-Qiong Liu, Xiao-Jie Ju, Xing-Long Zhou, Xiao-Ting Mu, Xiao-Yu Tian, Lu Zhang, Zhuang Liu, Wei Wang, Rui Xie and Liang-Yin Chu

Journal of Hazardous Materials, 2022, 421, 126801
DOI: 10.1016/j.jhazmat.2021.126801

An oligonucleotide-based switch-on luminescent probe for the detection of kanamycin in aqueous solution

Ka-Ho Leung, Hong-Zhang He, Daniel Shiu-Hin Chan, Wai-Chung Fu, Chung-Hang Leung and Dik-Lung Ma

Sensors and Actuators B: Chemical, 2013, 177, 487
DOI: 10.1016/j.snb.2012.11.053

Ultrasensitive optical detection of strontium ions by specific nanosensor with ultrahigh binding affinity

Xinfeng Du, Hua Xie, Tianyi Qin, Yihui Yuan and Ning Wang

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-50895-9

Ultrasensitive and highly selective detection of strontium ions

Lijuan Feng, Hui Wang, Tingting Liu, Tiantian Feng, Meng Cao, Jiacheng Zhang, Tao Liu, Zhanhu Guo, Costas Galiotis, Yihui Yuan and Ning Wang

Nat Sustain, 2023, 6, 789
DOI: 10.1038/s41893-023-01095-8

Group 9 Organometallic Compounds for Therapeutic and Bioanalytical Applications

Dik-Lung Ma, Daniel Shiu-Hin Chan and Chung-Hang Leung

Acc. Chem. Res., 2014, 47, 3614
DOI: 10.1021/ar500310z

Label-free Detection of Zn2+ Based on G-quadruplex

Yahui Guo, Yan Sun, Xiaoqiang Shen, Kunchi Zhang, Jiming Hu and Renjun Pei

ANAL. SCI., 2015, 31, 1041
DOI: 10.2116/analsci.31.1041

Nanoparticle intervention for heavy metal detection: A review

Priya Shrivastava, V.K Jain and Suman Nagpal

Environmental Nanotechnology, Monitoring & Management, 2022, 17, 100667
DOI: 10.1016/j.enmm.2022.100667

Recent Developments in G-Quadruplex Probes

Dik-Lung Ma, Zhihong Zhang, Modi Wang, Lihua Lu, Hai-Jing Zhong and Chung-Hang Leung

Chemistry & Biology, 2015, 22, 812
DOI: 10.1016/j.chembiol.2015.06.016

Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches

Eric Largy, Adrien Marchand, Samir Amrane, Valérie Gabelica and Jean-Louis Mergny

J. Am. Chem. Soc., 2016, 138, 2780
DOI: 10.1021/jacs.5b13130

Luminescent and colorimetric strategies for the label-free DNA-based detection of enzyme activity

C.-H. Leung, H.-J. Zhong, L. Lu, D. S.-H. Chan and D.-L. Ma

Briefings in Functional Genomics, 2013, 12, 525
DOI: 10.1093/bfgp/elt004

A Label-Free Luminescent Switch-On Assay for ATP Using a G-Quadruplex-Selective Iridium(III) Complex

Ka-Ho Leung, Lihua Lu, Modi Wang, Tsun-Yin Mak, Daniel Shiu-Hin Chan, Fung-Kit Tang, Chung-Hang Leung, Hiu-Yee Kwan, Zhiling Yu, Dik-Lung Ma and Andrew C. Marr

PLoS ONE, 2013, 8, e77021
DOI: 10.1371/journal.pone.0077021

A G-triplex-based label-free fluorescence switching platform for the specific recognition of chromium species

Qiusha Li, Shuzhen Peng, Yun Chang, Mujing Yang, Dandan Wang, Xiaoshun Zhou and Yong Shao

Journal of Photochemistry and Photobiology A: Chemistry, 2022, 432, 114071
DOI: 10.1016/j.jphotochem.2022.114071

Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe

Hong-Zhang He, Ka-Ho Leung, Hui Yang, Daniel Shiu-Hin Chan, Chung-Hang Leung, Jun Zhou, Anne Bourdoncle, Jean-Louis Mergny and Dik-Lung Ma

Biosensors and Bioelectronics, 2013, 41, 871
DOI: 10.1016/j.bios.2012.08.060

Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes

Helena Guiset Miserachs, Daniela Donghi, Richard Börner, Silke Johannsen and Roland K. O. Sigel

J Biol Inorg Chem, 2016, 21, 975
DOI: 10.1007/s00775-016-1393-4

Polarity inversion sensitized G-quadruplex metal sensors with K+ tolerance

Ting Ye, Heng Gao, Qingqing Zhang, Chenxiao Yan, Yali Yu, Yifan Fei, Longlong Gao, Xiaoshun Zhou and Yong Shao

Biosensors and Bioelectronics, 2019, 145, 111703
DOI: 10.1016/j.bios.2019.111703

Human telomeric G-quadruplex DNA enabled preferential recognition of copper (II) and Iron (III) ions sensed by a red emissive probe

Pankaj Ombase, Rajesh Kumar Patidar, Lachhman Singh, Jaya Baranwal, Nidhi Srivastava and Nihar Ranjan

Tetrahedron Letters, 2022, 111, 154181
DOI: 10.1016/j.tetlet.2022.154181

Design, synthesis, and selective sensing of Sr2+ ions using fluorescent aryl acetamide sensors with computational and biological investigations

A. Subhasri, S. Balachandran, M. Chandrakanth, S. Sowmiya, S. Vasugi, Sandhanasamy Devanesan and Mohamad S AlSalhi

Journal of Molecular Structure, 2025, 1333, 141739
DOI: 10.1016/j.molstruc.2025.141739

Fluorescent Probes for Monitoring Toxic Elements from the Nuclear Industry: A Review

Clovis Poulin-Ponnelle, Denis Boudreau and Dominic Larivière

Sensors, 2025, 25, 5835
DOI: 10.3390/s25185835

A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3′–5′ proofreading activity

Ka-Ho Leung, Hong-Zhang He, Hai-Jing Zhong, Lihua Lu, Daniel Shiu-Hin Chan, Dik-Lung Ma and Chung-Hang Leung

Methods, 2013, 64, 224
DOI: 10.1016/j.ymeth.2013.05.017

A highly selective fluorescent sensor for Ca2+ and Sr2+ based on diarylethene with a furan-carbohydrazide unit

Hongling Liu, Shiqiang Cui, Fu Shi and Shouzhi Pu

Tetrahedron, 2019, 75, 3772
DOI: 10.1016/j.tet.2019.05.056

A Ruthenium(II) Complex Supported by Trithiacyclononane and Aromatic Diimine Ligand as Luminescent Switch-On Probe for Biomolecule Detection and Protein Staining

Chun-Yuen Wong, Lai-Hon Chung, Sheng Lin, Daniel Shiu-Hin Chan, Chung-Hang Leung and Dik-Lung Ma

Sci Rep, 2014, 4
DOI: 10.1038/srep07136

Development of an Iridium(III) Complex as a G-Quadruplex Probe and Its Application for the G-Quadruplex-Based Luminescent Detection of Picomolar Insulin

Modi Wang, Wanhe Wang, Tian-Shu Kang, Chung-Hang Leung and Dik-Lung Ma

Anal. Chem., 2016, 88, 981
DOI: 10.1021/acs.analchem.5b04064

Application of a DNA-based luminescence switch-on method for the detection of mercury(II) ions in water samples from Hong Kong

Hong-Zhang He, Ka-Ho Leung, Wai-Chung Fu, Daniel Shiu-Hin Chan, Chung-Hang Leung and Dik-Lung Ma

Environ. Res. Lett., 2012, 7, 044032
DOI: 10.1088/1748-9326/7/4/044032

MOF-based probes for total content detection of Ca2+/Sr2+----Regulating detection performance indicators of probes via "paramagnetic/diamagnetic heterometallic probes" strategy

Pei-Pei Zhang, Bo-Lun Zhang, Wen-Jing Shi, Jun Chen, Wen-Tao Song, Jian-Jun Zhang, Shuqin Liu and Jun Ni

Sensors and Actuators B: Chemical, 2024, 413, 135888
DOI: 10.1016/j.snb.2024.135888

A tutorial review for employing enzymes for the construction of G-quadruplex-based sensing platforms

Dik-Lung Ma, Wanhe Wang, Zhifeng Mao, Chao Yang, Xiu-Ping Chen, Jin-Jian Lu, Quan-Bin Han and Chung-Hang Leung

Analytica Chimica Acta, 2016, 913, 41
DOI: 10.1016/j.aca.2016.01.043

Metal Sensing by DNA

Wenhu Zhou, Runjhun Saran and Juewen Liu

Chem. Rev., 2017, 117, 8272
DOI: 10.1021/acs.chemrev.7b00063

G-Quadruplexes as Sensing Probes

Branislav Ruttkay-Nedecky, Jiri Kudr, Lukas Nejdl, Darina Maskova, Rene Kizek and Vojtech Adam

Molecules, 2013, 18, 14760
DOI: 10.3390/molecules181214760

Unraveling the Possibilities: Recent Progress in DNA Biosensing

Meng Yu, Tingli He, Qianqian Wang and Cheng Cui

Biosensors, 2023, 13, 889
DOI: 10.3390/bios13090889

2′‐5′‐Isomerically Linked Thrombin‐Binding Aptamer (isoTBA) Forms a Stable Unimolecular Parallel G‐Quadruplex in the Presence of Sr2+ Ions

Atish A. Wagh and Moneesha Fernandes

ChemistrySelect, 2019, 4, 10668
DOI: 10.1002/slct.201902005

Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy

Ana Zamora, Gloria Vigueras, Venancio Rodríguez, M. Dolores Santana and José Ruiz

Coordination Chemistry Reviews, 2018, 360, 34
DOI: 10.1016/j.ccr.2018.01.010

A Highly Selective and Non-Reaction Based Chemosensor for the Detection of Hg2+ Ions Using a Luminescent Iridium(III) Complex

Daniel Shiu-Hin Chan, Wai-Chung Fu, Modi Wang, Li-Juan Liu, Chung-Hang Leung, Dik-Lung Ma and Andrew C. Marr

PLoS ONE, 2013, 8, e60114
DOI: 10.1371/journal.pone.0060114

G-quadruplexes for luminescent sensing and logic gates

H.-Z. He, D. S.-H. Chan, C.-H. Leung and D.-L. Ma

Nucleic Acids Research, 2013, 41, 4345
DOI: 10.1093/nar/gkt108

Ruthenium(II) and Iridium(III) Complexes as Tested Materials for New Anticancer Agents

Joanna Masternak, Agnieszka Gilewska, Barbara Barszcz, Iwona Łakomska, Katarzyna Kazimierczuk, Jerzy Sitkowski, Joanna Wietrzyk, Anna Kamecka and Magdalena Milczarek

Materials, 2020, 13, 3491
DOI: 10.3390/ma13163491