A selenium-containing ruthenium complex as a cancer radiosensitizer, rational design and the important role of ROS-mediated signalling

Zhiqin Deng, Lianling Yu, Wenqiang Cao, Wenjie Zheng and Tianfeng Chen

Chem. Commun., 2015, 51, 2637
DOI: 10.1039/C4CC07926D

Differential effects of amino acid surface decoration on the anticancer efficacy of selenium nanoparticles

Yanxian Feng, Jianyu Su, Zhennan Zhao, Wenjie Zheng, Hualian Wu, Yibo Zhang and Tianfeng Chen

Dalton Trans., 2014, 43, 1854
DOI: 10.1039/C3DT52468J

Zinc(ii) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells

Shenggui Liu, Wenqiang Cao, Lianling Yu, Wenjie Zheng, Linlin Li, Cundong Fan and Tianfeng Chen

Dalton Trans., 2013, 42, 5932
DOI: 10.1039/c3dt33077j

Phycocyanin-based nanocarrier as a new nanoplatform for efficient overcoming of cancer drug resistance

Yanyu Huang, Lizhen He, Zhenhuan Song, Leung Chan, Jintao He, Wei Huang, Binwei Zhou and Tianfeng Chen

J. Mater. Chem. B, 2017, 5, 3300
DOI: 10.1039/C7TB00287D

Zn(ii), Cd(ii) and Hg(ii) saccharinate complexes with 2,6-bis(2-benzimidazolyl)pyridine as promising anticancer agents in breast and lung cancer cell linesviaROS-induced apoptosis

Ceyda Icsel, Veysel T. Yilmaz, Seyma Aydinlik and Muhittin Aygun

Dalton Trans., 2020, 49, 7842
DOI: 10.1039/D0DT01535K

A Ru(ii)-arene-ferrocene complex with promising antibacterial activity

Stephen Mensah, Joseph D. Rosenthal, Mamta Dagar, Tyson Brown, Jonathan J. Mills, Christopher G. Hamaker, Gregory M. Ferrence and Michael I. Webb

Dalton Trans., 2022, 51, 17609
DOI: 10.1039/D2DT02696A

Selenadiazole derivatives as theranostic agents for simultaneous cancer chemo-/radiotherapy by targeting thioredoxin reductase

Lizhen He, Shengbin Ji, Haoqiang Lai and Tianfeng Chen

J. Mater. Chem. B, 2015, 3, 8383
DOI: 10.1039/C5TB01501D

Metallomics insights into the programmed cell death induced by metal-based anticancer compounds

Cai-Ping Tan, Yi-Ying Lu, Liang-Nian Ji and Zong-Wan Mao

Metallomics, 2014, 6, 978
DOI: 10.1039/c3mt00225j

Antiangiogenic ruthenium(ii) benzimidazole complexes, structure-based activation of distinct signaling pathways

Haoqiang Lai, Zhennan Zhao, Linlin Li, Wenjie Zheng and Tianfeng Chen

Metallomics, 2015, 7, 439
DOI: 10.1039/C4MT00312H

Interaction of metal complexes with nucleic acids

A. Łęczkowska and R. Vilar

Annu. Rep. Prog. Chem., Sect. A: Inorg. Chem., 2013, 109, 299
DOI: 10.1039/c3ic90029k

Molecular targets and anticancer activity of quinoline–chalcone hybrids: literature review

Mamdouh F. A. Mohamed and Gamal El-Din A. Abuo-Rahma

RSC Adv., 2020, 10, 31139
DOI: 10.1039/D0RA05594H

Nucleolin-targeted selenium nanocomposites with enhanced theranostic efficacy to antagonize glioblastoma

Lizhen He, Lilan Zeng, Xiaoxuan Mai, Changzheng Shi, Liangping Luo and Tianfeng Chen

J. Mater. Chem. B, 2017, 5, 3024
DOI: 10.1039/C6TB03365B

Influence of substituents on DNA and protein binding of cyclometalated Ir(iii) complexes and anticancer activity

Sujay Mukhopadhyay, Roop Shikha Singh, Rajendra Prasad Paitandi, Gunjan Sharma, Biplob Koch and Daya Shankar Pandey

Dalton Trans., 2017, 46, 8572
DOI: 10.1039/C7DT01015J

Functionalization and cancer-targeting design of ruthenium complexes for precise cancer therapy

Jinggong Liu, Haoqiang Lai, Zushuang Xiong, Bolai Chen and Tianfeng Chen

Chem. Commun., 2019, 55, 9904
DOI: 10.1039/C9CC04098F

Unconventional DNA-relevant π-stacked hydrogen bonded arrays involving supramolecular guest benzoate dimers and cooperative anion–π/π–π/π–anion contacts in coordination compounds of Co(ii) and Zn(ii) phenanthroline: experimental and theoretical studies

Manjit K. Bhattacharyya, Utpal Saha, Debajit Dutta, Antonio Frontera, Akalesh K. Verma, Pranay Sharma and Amal Das

New J. Chem., 2020, 44, 4504
DOI: 10.1039/C9NJ05727G

Highly stable selenadiazole derivatives induce bladder cancer cell apoptosis and inhibit cell migration and invasion through the activation of ROS-mediated signaling pathways

Yahui Yang, Shulin Deng, Qinsong Zeng, Weilie Hu and Tianfeng Chen

Dalton Trans., 2016, 45, 18465
DOI: 10.1039/C6DT02045C

Selenadiazole derivatives antagonize hyperglycemia-induced drug resistance in breast cancer cells by activation of AMPK pathways

Jianfu Zhao, Delong Zeng, Yuedan Liu, Yi Luo, Shengbin Ji, Xiaoling Li and Tianfeng Chen

Metallomics, 2017, 9, 535
DOI: 10.1039/C7MT00001D

Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling

Zhennan Zhao, Zuandi Luo, Qiong Wu, Wenjie Zheng, Yanxian Feng and Tianfeng Chen

Dalton Trans., 2014, 43, 17017
DOI: 10.1039/C4DT01392A

DNA Binding and Anti-Cancer Activity of Redox-Active Heteroleptic Piano-Stool Ru(II), Rh(III), and Ir(III) Complexes Containing 4-(2-Methoxypyridyl)phenyldipyrromethene

Rakesh Kumar Gupta, Rampal Pandey, Gunjan Sharma, Ritika Prasad, Biplob Koch, Saripella Srikrishna, Pei-Zhou Li, Qiang Xu and Daya Shankar Pandey

Inorg. Chem., 2013, 52, 3687
DOI: 10.1021/ic302196v

Synthesis, characterization, and antitumor properties of ruthenium(II) anthraquinone complexes

Jin-Quan Wang, Zi-Zhuo Zhao, Hua-Ben Bo and Qi-Zhu Chen

Journal of Coordination Chemistry, 2016, 69, 177
DOI: 10.1080/00958972.2015.1120291

Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes

Sujay Mukhopadhyay, Rakesh Kumar Gupta, Rajendra Prasad Paitandi, Nishant Kumar Rana, Gunjan Sharma, Biplob Koch, Love Karan Rana, Maninder Singh Hundal and Daya Shankar Pandey

Organometallics, 2015, 34, 4491
DOI: 10.1021/acs.organomet.5b00475

Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats

Carlos Eduardo Alves de Souza, Helen de Morais Alves de Souza, Maria Carolina Stipp, Claudia Rita Corso, Claudia Martins Galindo, Carolina Riverin Cardoso, Rosangela Locatelli Dittrich, Edneia Amancio de Souza Ramos, Giseli Klassen, Rose Maria Carlos, Sílvia Maria Suter Correia Cadena and Alexandra Acco

Free Radical Biology and Medicine, 2017, 110, 228
DOI: 10.1016/j.freeradbiomed.2017.06.011

Metal-Based Anticancer Complexes and p53: How Much Do We Know?

Samah Mutasim Alfadul, Egor M. Matnurov, Alexander E. Varakutin and Maria V. Babak

Cancers, 2023, 15, 2834
DOI: 10.3390/cancers15102834

Two Half-Sandwiched Ruthenium (II) Compounds Containing 5-Fluorouracil Derivatives: Synthesis and Study of DNA Intercalation

Zhao-Jun Li, Yong Hou, Da-An Qin, Zhi-Min Jin, Mao-Lin Hu and Heidar-Ali Tajmir-Riahi

PLoS ONE, 2015, 10, e0120211
DOI: 10.1371/journal.pone.0120211

Functionalized Selenium Nanosystem as Radiation Sensitizer of 125I Seeds for Precise Cancer Therapy

Yahui Yang, Qiang Xie, Zhennan Zhao, Lizhen He, Leung Chan, Yingxiang Liu, Yongle Chen, Mingjun Bai, Tao Pan, Yanni Qu, Long Ling and Tianfeng Chen

ACS Appl. Mater. Interfaces, 2017, 9, 25857
DOI: 10.1021/acsami.7b07167

Antiproliferative evaluation and supramolecular association involving electrostatically enhanced π-π interaction in isostructural coordination solids of Mn(II), Co(II) and Zn(II) chlorobenzoates: Experimental and theoretical studies

Swah Mohd. Nashre-ul-Islam, Debajit Dutta, Akalesh K. Verma, Hiren Nath, Antonio Frontera, Pranay Sharma and Manjit K. Bhattacharyya

Inorganica Chimica Acta, 2019, 498, 119161
DOI: 10.1016/j.ica.2019.119161

Synthesis, characterization, and anticancer activity of ruthenium(II)-β-carboline complex

Yu Chen, Meng-Ying Qin, Jing-Heng Wu, Lei Wang, Hui Chao, Liang-Nian Ji and An-Long Xu

European Journal of Medicinal Chemistry, 2013, 70, 120
DOI: 10.1016/j.ejmech.2013.09.051

Rational Design of Ruthenium Complexes Containing 2,6‐Bis(benzimidazolyl)pyridine Derivatives with Radiosensitization Activity by Enhancing p53 Activation

Zhiqin Deng, Lianling Yu, Wenqiang Cao, Wenjie Zheng and Tianfeng Chen

ChemMedChem, 2015, 10, 991
DOI: 10.1002/cmdc.201500127

Local DNA microviscosity converts ruthenium polypyridyl complexes to ultrasensitive photosensitizers

Prashant Kumar, Falguni Chandra, Paltan Laha, Kavyashree P., Srikanta Patra and Apurba Lal Koner

Journal of Molecular Liquids, 2021, 344, 117788
DOI: 10.1016/j.molliq.2021.117788

A simple 2,6-bis(2-benzimidazole)pyridyl incorporated optical probe affording selective ratiometric targeting of biologically and environmentally significant Zn2+ under buffer condition

Sabir H. Mashraqui, Mukesh Chandiramani, Sushil Ghorpade, Jyoti Upathayay, Rupesh Mestri and Aniket Chilekar

J Incl Phenom Macrocycl Chem, 2016, 84, 129
DOI: 10.1007/s10847-015-0590-z

Synthesis, characterization and anticancer activity in vitro and in vivo evaluation of an iridium (III) polypyridyl complex

Qiao-Yan Yi, Dan Wan, Bing Tang, Yang-Jie Wang, Wen-Yao Zhang, Fan Du, Miao He and Yun-Jun Liu

European Journal of Medicinal Chemistry, 2018, 145, 338
DOI: 10.1016/j.ejmech.2017.11.091

Cellular localization of iron(II) polypyridyl complexes determines their anticancer action mechanisms

Jingjing Chen, Zuandi Luo, Zhennan Zhao, Lina Xie, Wenjie Zheng and Tianfeng Chen

Biomaterials, 2015, 71, 168
DOI: 10.1016/j.biomaterials.2015.08.031

Iron(II)−Polypyridyl Complexes Inhibit the Growth of Glioblastoma Tumor and Enhance TRAIL‐Induced Cell Apoptosis

Hao Lin, Yifan Wang, Haoqiang Lai, Xiaoling Li and Tianfeng Chen

Chemistry An Asian Journal, 2018, 13, 2730
DOI: 10.1002/asia.201800862

Cytoxicity and Apoptotic Mechanism of Ruthenium(II) Amino Acid Complexes in Sarcoma-180 Tumor Cells

Aliny Pereira Lima, Flávia Castro Pereira, Marcio Aurelio Pinheiro Almeida, Francyelli Mariana Santos Mello, Wanessa Carvalho Pires, Thallita Monteiro Pinto, Flávia Karina Delella, Sérgio Luis Felisbino, Virtudes Moreno, Alzir Azevedo Batista, Elisângela de Paula Silveira-Lacerda and Arun Rishi

PLoS ONE, 2014, 9, e105865
DOI: 10.1371/journal.pone.0105865

Synthesis and characterization of chiral ruthenium(II) complexes Λ/Δ-[Ru(bpy)2(H2iip)](ClO4)2 as stabilizers of c-myc G-quadruplex DNA

Zhao Zhang, Wenjie Mei, Xiaohui Wu, Xicheng Wang, Baoguo Wang and Sidong Chen

Journal of Coordination Chemistry, 2015, 68, 1465
DOI: 10.1080/00958972.2015.1014352

The potential anti-proliferative effect of β-sitosterol on human mast cell line-1 cells

Na-Ra Han, Hyung-Min Kim and Hyun-Ja Jeong

Can. J. Physiol. Pharmacol., 2015, 93, 979
DOI: 10.1139/cjpp-2015-0166

New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway

Kang Chen, Bi-zhu Chu, Feng Liu, Bin Li, Chun-mei Gao, Lu-lu Li, Qin-sheng Sun, Zhi-fa Shen and Yu-yang Jiang

Acta Pharmacol Sin, 2015, 36, 1074
DOI: 10.1038/aps.2015.44

A ruthenium(II) β-carboline complex induced p53-mediated apoptosis in cancer cells

Yu Chen, Meng-Ying Qin, Lei Wang, Hui Chao, Liang-Nian Ji and An-Long Xu

Biochimie, 2013, 95, 2050
DOI: 10.1016/j.biochi.2013.07.016

Green tea polyphenols induce cell death in breast cancer MCF-7 cells through induction of cell cycle arrest and mitochondrial-mediated apoptosis

Shu-min Liu, Shi-yi Ou and Hui-hua Huang

J. Zhejiang Univ. Sci. B, 2017, 18, 89
DOI: 10.1631/jzus.B1600022

DNA condensation by copper(II) complexes and their anti-proliferative effect on cancerous and normal fibroblast cells

Subramaniyam Rajalakshmi, Manikantan Syamala Kiran and Balachandran Unni Nair

European Journal of Medicinal Chemistry, 2014, 80, 393
DOI: 10.1016/j.ejmech.2014.04.064

Inhibition of islet amyloid polypeptide fibril formation by selenium-containing phycocyanin and prevention of beta cell apoptosis

Xiaoling Li, Lijuan Ma, Wenjie Zheng and Tianfeng Chen

Biomaterials, 2014, 35, 8596
DOI: 10.1016/j.biomaterials.2014.06.056

Energetically significant antiparallel π-stacking contacts in Co(II), Ni(II) and Cu(II) coordination compounds of pyridine-2,6-dicarboxylates: Antiproliferative evaluation and theoretical studies

Manjit K. Bhattacharyya, Debajit Dutta, Swah Mohd. Nashre-ul-Islam, Antonio Frontera, Pranay Sharma, Akalesh K. Verma and Amal Das

Inorganica Chimica Acta, 2020, 501, 119233
DOI: 10.1016/j.ica.2019.119233

Ruthenium(II) complexes: DNA-binding, cytotoxicity, apoptosis, cellular localization, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential and western blot analysis

Wei Li, Guang-Bin Jiang, Jun-Hua Yao, Xiu-Zhen Wang, Ji Wang, Bing-Jie Han, Yang-Yin Xie, Gan-Jian Lin, Hong-Liang Huang and Yun-Jun Liu

Journal of Photochemistry and Photobiology B: Biology, 2014, 140, 94
DOI: 10.1016/j.jphotobiol.2014.07.011

Antiproliferative evaluation and supramolecular association in Mn(II) and Zn(II) bipyridine complexes: Combined experimental and theoretical studies

Manjit K. Bhattacharyya, Anshuman Gogoi, Sanjib Chetry, Debajit Dutta, Akalesh K. Verma, Bipul Sarma, Antonio Franconetti and Antonio Frontera

Journal of Inorganic Biochemistry, 2019, 200, 110803
DOI: 10.1016/j.jinorgbio.2019.110803

DNA/Protein Binding, Molecular Docking, and in Vitro Anticancer Activity of Some Thioether-Dipyrrinato Complexes

Rakesh Kumar Gupta, Gunjan Sharma, Rampal Pandey, Amit Kumar, Biplob Koch, Pei-Zhou Li, Qiang Xu and Daya Shankar Pandey

Inorg. Chem., 2013, 52, 13984
DOI: 10.1021/ic401662d

Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling

Antonio Rescifina, Chiara Zagni, Maria Giulia Varrica, Venerando Pistarà and Antonino Corsaro

European Journal of Medicinal Chemistry, 2014, 74, 95
DOI: 10.1016/j.ejmech.2013.11.029

Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling

Cundong Fan, Wenjie Zheng, Xiaoyan Fu, Xiaoling Li, Yum-Shing Wong and Tianfeng Chen

Oncotarget, 2014, 5, 2853
DOI: 10.18632/oncotarget.1854

Ruthenium complexes with phenylterpyridine derivatives target cell membrane and trigger death receptors-mediated apoptosis in cancer cells

Zhiqin Deng, Pan Gao, Lianling Yu, Bin Ma, Yuanyuan You, Leung Chan, Chaoming Mei and Tianfeng Chen

Biomaterials, 2017, 129, 111
DOI: 10.1016/j.biomaterials.2017.03.017

pH dependent spectrophotometric study, cytotoxicity and antimicrobial activity of mononuclear ruthenium(II) polypyridine complexes

F. Catharine Priya and D. Suresh Kumar

Materials Today: Proceedings, 2023
DOI: 10.1016/j.matpr.2023.03.361

Benzimidazole ligands with allyl, propargyl or allene groups, DNA binding properties, and molecular docking studies

Enes Turgut, Ozge Gungor, Hilal Kirpik, Ayşegül Kose, Seyit Ali Gungor and Muhammet Kose

Applied Organom Chemis, 2021, 35
DOI: 10.1002/aoc.6323

Aquation Is a Crucial Activation Step for Anticancer Action of Ruthenium(II) Polypyridyl Complexes to Trigger Cancer Cell Apoptosis

Meng Li, Lanhai Lai, Zhennan Zhao and Tianfeng Chen

Chemistry An Asian Journal, 2016, 11, 310
DOI: 10.1002/asia.201501048