Applications of luminescent inorganic and organometallic transition metal complexes as biomolecular and cellular probes

Kenneth Kam-Wing Lo, Alex Wing-Tat Choi and Wendell Ho-Tin Law

Dalton Trans., 2012, 41, 6021
DOI: 10.1039/c2dt11892k

Synthesis and anticancer mechanisms of four novel platinum(ii) 4′-substituted-2,2′:6′,2′′-terpyridine complexes

Chun-Jie Liang, Run-Chun Wu, Xiao-Qiong Huang, Qi-Pin Qin, Hong Liang and Ming-Xiong Tan

Dalton Trans., 2024, 53, 2143
DOI: 10.1039/D3DT03197G

4,5-Substituted C^C* cyclometalated thiazol-2-ylidene platinum(ii) complexes – synthesis and photophysical properties

Hendrik Leopold and Thomas Strassner

Dalton Trans., 2017, 46, 7800
DOI: 10.1039/C7DT00828G

Luminescent bioactive NHC–metal complexes to bring light into cells

Catherine Hemmert and Heinz Gornitzka

Dalton Trans., 2016, 45, 440
DOI: 10.1039/C5DT03904E

A highly efficient and selective antitumor agent based on a glucoconjugated carbene platinum(ii) complex

Alfonso Annunziata, Maria Elena Cucciolito, Roberto Esposito, Paola Imbimbo, Ganna Petruk, Giarita Ferraro, Valerio Pinto, Angela Tuzi, Daria Maria Monti, Antonello Merlino and Francesco Ruffo

Dalton Trans., 2019, 48, 7794
DOI: 10.1039/C9DT01614G

Temperature dependence of photophysical properties of a dinuclear C^N-cyclometalated Pt(ii) complex with an intimate Pt–Pt contact. Zero-field splitting and sub-state decay rates of the lowest triplet

Joseph C. Deaton, Arnab Chakraborty, Rafal Czerwieniec, Hartmut Yersin and Felix N. Castellano

Phys. Chem. Chem. Phys., 2018, 20, 25096
DOI: 10.1039/C8CP05213A

Luminous block copolymer–quantum dots hybrids formed by cooperative assembly in a selective solvent

Xiaobo Nie and Wei Jiang

RSC Adv., 2014, 4, 19613
DOI: 10.1039/c4ra02175d

Iridium(iii)-based minor groove binding complexes as DNA photocleavage agents

Stephen O. Aderinto, Torsten John, Abdulmujeeb Onawole, Raphael Peter Galleh and Jim A. Thomas

Dalton Trans., 2024, 53, 7282
DOI: 10.1039/D4DT00171K

Bimetallic platinum(ii) complexes with bridging di-NHC and N^C^C ligands: synthesis and photophysical properties

Mariano Paredes, Dionisio Poveda, Pablo González-Herrero and Ángela Vivancos

Dalton Trans., 2025, 54, 15745
DOI: 10.1039/D5DT01761K

Synthesis, characterization, DNA binding and cleavage, BSA interaction and anticancer activity of dinuclear zinc complexes

Chun-Yan Gao, Xin Qiao, Zhong-Ying Ma, Zhi-Gang Wang, Jing Lu, Jin-Lei Tian, Jing-Yuan Xu and Shi-Ping Yan

Dalton Trans., 2012, 41, 12220
DOI: 10.1039/c2dt31306e

Micelle-to-vesicle morphological transition via light-induced rapid hydrophilic arm detachment from a star polymer

Jin-Zhi Du, Hong-Yan Long, You-Yong Yuan, Meng-Meng Song, Liang Chen, Hong Bi and Jun Wang

Chem. Commun., 2012, 48, 1257
DOI: 10.1039/C2CC16363B

Synthesis, characterization and biological activity of new cyclometallated platinum(iv) iodido complexes

Emma Bauer, Xavier Domingo, Cristina Balcells, Ibrahim H. Polat, Margarita Crespo, Josefina Quirante, Josefa Badía, Laura Baldomà, Mercè Font-Bardia and Marta Cascante

Dalton Trans., 2017, 46, 14973
DOI: 10.1039/C7DT03448B

Post-functionalization of platinum–NHC complexes by oxime ligation for ligand targeted therapy

Etienne Borré, Georges Dahm, Gilles Guichard and Stéphane Bellemin-Laponnaz

New J. Chem., 2016, 40, 3164
DOI: 10.1039/C5NJ03104D

Cycloplatinated(ii) complexes bearing 1,1′-bis(diphenylphosphino)ferrocene ligand: biological evaluation and molecular docking studies

Masood Fereidoonnezhad, Hamid R. Shahsavari, Sedigheh Abedanzadeh, Behnoosh Behchenari, Mojdeh Hossein-Abadi, Zahra Faghih and M. Hassan Beyzavi

New J. Chem., 2018, 42, 2385
DOI: 10.1039/C7NJ04183G

Visual self-assembly and stimuli-responsive materials based on recent phosphorescent platinum(ii) complexes

Baoning Li, Zhenjie Liang, Huijie Yan and Yongguang Li

Mol. Syst. Des. Eng., 2020, 5, 1578
DOI: 10.1039/D0ME00113A

Antimicrobial efficacy of a hemilabile Pt(ii)–NHC compound against drug-resistant S. aureus and Enterococcus

Mandeep Kaur, Ritesh Thakare, Arindom Bhattacherya, Prem Anand Murugan, Grace Kaul, Manjulika Shukla, Alok Kr. Singh, Saravanan Matheshwaran, Sidharth Chopra and Jitendra K. Bera

Dalton Trans., 2023, 52, 1876
DOI: 10.1039/D2DT03365H

Luminescent organoplatinum(ii) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity

Taotao Zou, Chun-Nam Lok, Yi Man Eva Fung and Chi-Ming Che

Chem. Commun., 2013, 49, 5423
DOI: 10.1039/c3cc40953h

Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: cellular characterization and mitochondria-specific localization

Zhengqing Guo, Wah-Leung Tong and Michael C. W. Chan

Chem. Commun., 2014, 50, 1711
DOI: 10.1039/c3cc47150k

Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(ii) complexes

Jia Liu, Raymond Wai-Yin Sun, Chung-Hang Leung, Chun-Nam Lok and Chi-Ming Che

Chem. Commun., 2012, 48, 230
DOI: 10.1039/C1CC15317J

Luminescent platinum(ii) complexes with self-assembly and anti-cancer properties: hydrogel, pH dependent emission color and sustained-release properties under physiological conditions

Johnson Lui-Lui Tsai, Taotao Zou, Jia Liu, Tianfeng Chen, Anna On-Yee Chan, Chen Yang, Chun-Nam Lok and Chi-Ming Che

Chem. Sci., 2015, 6, 3823
DOI: 10.1039/C4SC03635B

Seeded growth of two-dimensional dendritic gold nanostructures

Ming Pan, Hang Sun, Jun Wei Lim, Saidur Rahman Bakaul, Yi Zeng, Shuangxi Xing, Tom Wu, Qingyu Yan and Hongyu Chen

Chem. Commun., 2012, 48, 1440
DOI: 10.1039/C1CC14721H

Significant differences in the biological activity of mononuclear Cu(ii) and Ni(ii) complexes with the polyquinolinyl ligand

Jun-Ling Li, Lin Jiang, Bi-Wei Wang, Jin-Lei Tian, Wen Gu, Xin Liu and Shi-Ping Yan

New J. Chem., 2015, 39, 529
DOI: 10.1039/C4NJ00876F

Luminescent ruffled iridium(iii) porphyrin complexes containing N-heterocyclic carbene ligands: structures, spectroscopies and potent antitumor activities under dark and light irradiation conditions

Tsz-Lung Lam, Ka-Chung Tong, Chen Yang, Wai-Lun Kwong, Xiangguo Guan, Ming-De Li, Vanessa Kar-Yan Lo, Sharon Lai-Fung Chan, David Lee Phillips, Chun-Nam Lok and Chi-Ming Che

Chem. Sci., 2019, 10, 293
DOI: 10.1039/C8SC02920B

Transition metal substituted sandwich-type polyoxometalates with a strong metal–C (imidazole) bond as anticancer agents

Hongxia Zhao, Li Tao, Fengmin Zhang, Ying Zhang, Yanqing Liu, Hongjie Xu, Guowang Diao and Lubin Ni

Chem. Commun., 2019, 55, 1096
DOI: 10.1039/C8CC07884J

Stable luminescent iridium(iii) complexes with bis(N-heterocyclic carbene) ligands: photo-stability, excited state properties, visible-light-driven radical cyclization and CO2 reduction, and cellular imaging

Chen Yang, Faisal Mehmood, Tsz Lung Lam, Sharon Lai-Fung Chan, Yuan Wu, Chi-Shun Yeung, Xiangguo Guan, Kai Li, Clive Yik-Sham Chung, Cong-Ying Zhou, Taotao Zou and Chi-Ming Che

Chem. Sci., 2016, 7, 3123
DOI: 10.1039/C5SC04458H

Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs

Wukun Liu and Ronald Gust

Chem. Soc. Rev., 2013, 42, 755
DOI: 10.1039/C2CS35314H

Antitumor activity of tridentate pincer and related metal complexes

Shulei Wu, Zaoduan Wu, Qianyi Ge, Xing Zheng and Zehua Yang

Org. Biomol. Chem., 2021, 19, 5254
DOI: 10.1039/D1OB00577D

N-Heterocyclic carbene metal complexes in medicinal chemistry

Luciano Oehninger, Riccardo Rubbiani and Ingo Ott

Dalton Trans., 2013, 42, 3269
DOI: 10.1039/C2DT32617E

Scope of organometallic compounds based on transition metal-arene systems as anticancer agents: starting from the classical paradigm to targeting multiple strategies

Mehvash Zaki, Suboot Hairat and Elham S. Aazam

RSC Adv., 2019, 9, 3239
DOI: 10.1039/C8RA07926A

Platinum(iv) N-heterocyclic carbene complexes: their synthesis, characterisation and cytotoxic activity

M. Bouché, G. Dahm, M. Wantz, S. Fournel, T. Achard and S. Bellemin-Laponnaz

Dalton Trans., 2016, 45, 11362
DOI: 10.1039/C6DT01846G

Luminescent metal complexes of d6, d8 and d10 transition metal centres

Vivian Wing-Wah Yam and Keith Man-Chung Wong

Chem. Commun., 2011, 47, 11579
DOI: 10.1039/c1cc13767k

When self-assembly meets biology: luminescent platinum complexes for imaging applications

Matteo Mauro, Alessandro Aliprandi, Dedy Septiadi, Nermin Seda Kehr and Luisa De Cola

Chem. Soc. Rev., 2014, 43, 4144
DOI: 10.1039/C3CS60453E

Metallomics insights into the programmed cell death induced by metal-based anticancer compounds

Cai-Ping Tan, Yi-Ying Lu, Liang-Nian Ji and Zong-Wan Mao

Metallomics, 2014, 6, 978
DOI: 10.1039/c3mt00225j

Heteroleptic platinum(ii) NHC complexes with a C^C* cyclometalated ligand – synthesis, structure and photophysics

Alexander Tronnier, Ute Heinemeyer, Stefan Metz, Gerhard Wagenblast, Ingo Muenster and Thomas Strassner

J. Mater. Chem. C, 2015, 3, 1680
DOI: 10.1039/C4TC02575J

Luminescent pentafluorophenyl-cycloplatinated complexes: synthesis, characterization, photophysics, cytotoxicity and cellular imaging

J. R. Berenguer, J. G. Pichel, N. Giménez, E. Lalinde, M. T. Moreno and S. Piñeiro-Hermida

Dalton Trans., 2015, 44, 18839
DOI: 10.1039/C5DT02721G

Luminescent cyclometallated platinum(ii) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents

Yang Zhang, Qun Luo, Wei Zheng, Zhaoying Wang, Yu Lin, Erlong Zhang, Shuang Lü, Junfeng Xiang, Yao Zhao and Fuyi Wang

Inorg. Chem. Front., 2018, 5, 413
DOI: 10.1039/C7QI00346C

Antitumor properties and mechanisms of mitochondria-targeted Ag(i) and Au(i) complexes containing N-heterocyclic carbenes derived from cyclophanes

Yi Li, Gao-Feng Liu, Cai-Ping Tan, Liang-Nian Ji and Zong-Wan Mao

Metallomics, 2014, 6, 1460
DOI: 10.1039/C4MT00046C

Luminescent cyclometalated platinum(ii) complexes with acyclic diaminocarbene ligands: structural, photophysical and biological properties

Mónica Martínez-Junquera, Elena Lalinde, M. Teresa Moreno, Elvira Alfaro-Arnedo, Icíar P. López, Ignacio M. Larráyoz and José G. Pichel

Dalton Trans., 2021, 50, 4539
DOI: 10.1039/D1DT00480H

A comprehensive review on the photocatalytic activity of polythiophene-based nanocomposites against degradation of organic pollutants

Jannatun Zia, Fizzah Fatima and Ufana Riaz

Catal. Sci. Technol., 2021, 11, 6630
DOI: 10.1039/D1CY01129D

Anticancer cyclometalated complexes of platinum group metals and gold

Natalia Cutillas, Gorakh S. Yellol, Concepción de Haro, Consuelo Vicente, Venancio Rodríguez and José Ruiz

Coordination Chemistry Reviews, 2013, 257, 2784
DOI: 10.1016/j.ccr.2013.03.024

Luminescent PtII Complexes of Tridentate Cyclometalating 2,5‐Bis(aryl)‐pyridine Ligands

Maren Krause, Dimitrios Kourkoulos, Darío González‐Abradelo, Klaus Meerholz, Cristian A. Strassert and Axel Klein

Eur J Inorg Chem, 2017, 2017, 5215
DOI: 10.1002/ejic.201700792

Conducting polymer-noble metal nanoparticle hybrids: Synthesis mechanism application

Jie Han, Minggui Wang, Yimin Hu, Chuanqiang Zhou and Rong Guo

Progress in Polymer Science, 2017, 70, 52
DOI: 10.1016/j.progpolymsci.2017.04.002

Palladium complexes of bidentate pyridine N‐heterocyclic carbenes: Optical resolution, antimicrobial and cytotoxicity studies

Kar Bee Choo, Wee Li Mah, Sui Mae Lee, Wai Leng Lee and Yuen Lin Cheow

Applied Organom Chemis, 2018, 32
DOI: 10.1002/aoc.4377

Bis-N-heterocyclic carbene silver(I) and palladium(II) complexes: Efficient antiproliferative agents against breast cancer cells

Rosenani A. Haque, Noorhafizah Hasanudin, Mouayed A. Hussein, Safa A. Ahamed and Muhammad Adnan Iqbal

Inorganic and Nano-Metal Chemistry, 2017, 47, 131
DOI: 10.1080/15533174.2016.1157816

Bioaktive lumineszierende Übergangsmetallkomplexe für biomedizinische Anwendungen

Dik‐Lung Ma, Hong‐Zhang He, Ka‐Ho Leung, Daniel Shiu‐Hin Chan and Chung‐Hang Leung

Angewandte Chemie, 2013, 125, 7820
DOI: 10.1002/ange.201208414

PlatinER: A Highly Potent Anticancer Platinum(II) Complex that Induces Endoplasmic Reticulum Stress Driven Immunogenic Cell Death

Max Jing Rui Tham, Maria V. Babak and Wee Han Ang

Angew Chem Int Ed, 2020, 59, 19070
DOI: 10.1002/anie.202008604

Luminescent cyclometalated platinum compounds with N, P, and O^O ligands: Density‐functional theory studies and analysis of the anticancer potential

Jorge Leal, Gema Durá, Félix A. Jalón, Elisenda Zafon, Anna Massaguer, José Vicente Cuevas, Lucia Santos, Ana M. Rodríguez and Blanca R. Manzano

Applied Organom Chemis, 2023, 37
DOI: 10.1002/aoc.6983

Synthesis, Structure, and Reactivity of Dicarbene Dipalladium Complexes

Yunfei Li, Longguang Yang, Qian Chen, Changsheng Cao, Pei Guan, Guangsheng Pang and Yanhui Shi

Zeitschrift anorg allge chemie, 2013, 639, 575
DOI: 10.1002/zaac.201200425

Anticancer Gold(III) Porphyrins Target Mitochondrial Chaperone Hsp60

Di Hu, Yungen Liu, Yau‐Tsz Lai, Ka‐Chung Tong, Yi‐Man Fung, Chun‐Nam Lok and Chi‐Ming Che

Angew Chem Int Ed, 2016, 55, 1387
DOI: 10.1002/anie.201509612

(Acetylacetonato-κ2O,O′)[1-(4-bromophenyl-κC2)-3-methylimidazol-2-ylidene-κC2]platinum(II)

Mario Tenne, Yvonne Unger and Thomas Strassner

Acta Crystallogr C Cryst Struct Commun, 2012, 68, m203
DOI: 10.1107/S0108270112027783

Organometallic Compounds: An Opportunity for Chemical Biology?

Malay Patra and Gilles Gasser

ChemBioChem, 2012, 13, 1232
DOI: 10.1002/cbic.201200159

Caffeine derived platinum(II) N-heterocyclic carbene complexes with multiple anti-cancer activities

Jing-Jing Zhang, Chi-Ming Che and Ingo Ott

Journal of Organometallic Chemistry, 2015, 782, 37
DOI: 10.1016/j.jorganchem.2014.10.041

Recent development of transition metal complexes with in vivo antitumor activity

Jia-Xin Liang, Hai-Jing Zhong, Guanjun Yang, Kasipandi Vellaisamy, Dik-Lung Ma and Chung-Hang Leung

Journal of Inorganic Biochemistry, 2017, 177, 276
DOI: 10.1016/j.jinorgbio.2017.06.002

Recent developments of metal N-heterocyclic carbenes as anticancer agents

Sainath Babaji Aher, Prashant Narayan Muskawar, K. Thenmozhi and Pundlik Rambhau Bhagat

European Journal of Medicinal Chemistry, 2014, 81, 408
DOI: 10.1016/j.ejmech.2014.05.036

A Highly Stretchable and Autonomous Self‐Healing Polymer Based on Combination of Pt···Pt and π–π Interactions

Jin‐Feng Mei, Xiao‐Yong Jia, Jian‐Cheng Lai, Yang Sun, Cheng‐Hui Li, Jun‐Hua Wu, Yi Cao, Xiao‐Zeng You and Zhenan Bao

Macromol. Rapid Commun., 2016, 37, 1667
DOI: 10.1002/marc.201600428

Pincer‐Type Pt(II)‐NHC Antibody‐Drug Conjugate for HER‐2‐Targeted Chemoimmunotherapy

Tao Huang, Wan‐Qiong Huang, Gui‐Feng Huang, Xiao‐Long Wei, Yong‐Liang Huang, Tao Liu, Yungen Liu, Wen‐Xiu Ni and Chi‐Ming Che

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202403449

Metal/N‐Heterocyclic Carbene Complexes: Opportunities for the Development of Anticancer Metallodrugs

Federico Cisnetti and Arnaud Gautier

Angew Chem Int Ed, 2013, 52, 11976
DOI: 10.1002/anie.201306682

Pincer‐Type Platinum(II) Complexes Containing N‐Heterocyclic Carbene (NHC) Ligand: Structures, Photophysical and Anion‐Binding Properties, and Anticancer Activities

Kai Li, Taotao Zou, Yong Chen, Xiangguo Guan and Chi‐Ming Che

Chemistry A European J, 2015, 21, 7441
DOI: 10.1002/chem.201406453

Platinum (II) N‐heterocyclic carbene complexes: Synthesis, characterization and cytotoxic properties

Emine Özge Karaca, Osman Çiftçi, İlknur Özdemir, Gül Yakali, Muhittin Aygün, Nevin Gürbüz and İsmail Özdemir

Applied Organom Chemis, 2019, 33
DOI: 10.1002/aoc.4851

1,2,4-triazole-derived N-heterocyclic carbene complexes of platinum(II) as catalysts for hydroamination reactions and active anticancer agents

Van Ha Nguyen, Hung Huy Nguyen and Huy Hoang Do

Inorganic Chemistry Communications, 2020, 121, 108173
DOI: 10.1016/j.inoche.2020.108173

Hexanuclear Zn(II) and Mononuclear Cu(II) Complexes containing imino phenol ligands: Exploitation of their Catalytic and Biological Perspectives

Shyam Sundar Mondal, Manosree Chatterjee, Ranjay K. Tiwari, J.N. Behera, Nripen Chanda, Sourav Biswas and Tanmoy Kumar Saha

Applied Organom Chemis, 2019, 33
DOI: 10.1002/aoc.5011

Active Electrochemical Plasmonic Switching on Polyaniline‐Coated Gold Nanocrystals

Wenzheng Lu, Nina Jiang and Jianfang Wang

Advanced Materials, 2017, 29
DOI: 10.1002/adma.201604862

Inhibition of telomerase activity and SK-OV-3/DDP cell apoptosis by rhodium(III) and iron(III) complexes with 4′-(3-thiophenecarboxaldehyde)-2,2′:6′,2″-terpyridine

Qing-Min Wei, Zhen-Feng Wang, Qi-Pin Qin, Shu-Long Wang, Ming-Xiong Tan, Bi-Qun Zou, Peng-Fei Yao and Hong Liang

Inorganic Chemistry Communications, 2019, 102, 180
DOI: 10.1016/j.inoche.2019.02.030

Preparation of platinum(II) complexes with naphthalene imide derivatives and exploration of their in vitro cytotoxic activities

Guo-Bao Huang, Shan Chen, Qi-Pin Qin, Jin-Rong Luo, Ming-Xiong Tan, Zhen-Feng Wang, Bi-Qun Zou and Hong Liang

Inorganic Chemistry Communications, 2019, 104, 124
DOI: 10.1016/j.inoche.2019.04.004

Cytotoxicity of cyclometalated platinum complexes based on tridentate NCN and CNN-coordinating ligands: Remarkable coordination dependence

Dileep A.K. Vezzu, Qun Lu, Yan-Hua Chen and Shouquan Huo

Journal of Inorganic Biochemistry, 2014, 134, 49
DOI: 10.1016/j.jinorgbio.2014.01.021

Monosaccharide Linked Schiff Base Metal Complexes of Cu(II), Zn(II) and Mn(II): Exploring the Antiproliferative Activity and Cell Death Mechanism

Shyam Sundar Mondal, Namita Jaiswal, Rajat Kumar Tripathy, Partha Sarathi Bera, Nripen Chanda, J. N. Behera, Subhas Ghosal and Tanmoy Kumar Saha

ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202200060

Anticancer Gold(III) Porphyrins Target Mitochondrial Chaperone Hsp60

Di Hu, Yungen Liu, Yau‐Tsz Lai, Ka‐Chung Tong, Yi‐Man Fung, Chun‐Nam Lok and Chi‐Ming Che

Angewandte Chemie, 2016, 128, 1409
DOI: 10.1002/ange.201509612

Structure-activity relationships for highly potent half-sandwich organoiridium(III) anticancer complexes with C^N-chelated ligands

Yuliang Yang, Lihua Guo, Xingxing Ge, Shaopeng Shi, Yuteng Gong, Zhishan Xu, Xiaofeng Zheng and Zhe Liu

Journal of Inorganic Biochemistry, 2019, 191, 1
DOI: 10.1016/j.jinorgbio.2018.11.007

Cyclometalated Gold(III) Complexes Containing N‐Heterocyclic Carbene Ligands Engage Multiple Anti‐Cancer Molecular Targets

Sin Ki Fung, Taotao Zou, Bei Cao, Pui‐Yan Lee, Yi Man Eva Fung, Di Hu, Chun‐Nam Lok and Chi‐Ming Che

Angewandte Chemie, 2017, 129, 3950
DOI: 10.1002/ange.201612583

Synthesis, Structural Characterization and Anti‐Proliferative Activity of (κ1‐C)‐ and (κ2‐C,S)‐PtII Complexes Bearing Thioether‐Functionalized N‐Heterocyclic Carbenes

Julien Egly, Mathilde Bouché, Weighang Chen, Aline Maisse‐François, Thierry Achard and Stéphane Bellemin‐Laponnaz

Eur J Inorg Chem, 2018, 2018, 159
DOI: 10.1002/ejic.201701183

Engineering Supramolecular Assemblies via Metal–Metal Interactions for Biological Applications

Maomao He, Xuequan Zhou, Yuanyuan He, Jiangli Fan, Xiaojun Peng, Jong Seung Kim and Wen Sun

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202516383

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N‐Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

Taotao Zou, Ching Tung Lum, Chun‐Nam Lok, Wai‐Pong To, Kam‐Hung Low and Chi‐Ming Che

Angew Chem Int Ed, 2014, 53, 5810
DOI: 10.1002/anie.201400142

Induced Coiling Action: Exploring the Intrinsic Defects in Five-Fold Twinned Silver Nanowires

Liangfang Zhu, Xiaoshuang Shen, Zhiyuan Zeng, Hong Wang, Hua Zhang and Hongyu Chen

ACS Nano, 2012, 6, 6033
DOI: 10.1021/nn301096n

Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA

Sin Ki Fung, Taotao Zou, Bei Cao, Tianfeng Chen, Wai-Pong To, Chen Yang, Chun-Nam Lok and Chi-Ming Che

Nat Commun, 2016, 7
DOI: 10.1038/ncomms10655

Self-activated DNA cleavage of a water-soluble mononuclear Cu(II) complex with polyquinolinyl ligand

Jun-Ling Li, Lin Jiang, Si-Tong Li, Jin-Lei Tian, Wen Gu, Xin Liu and Shi-Ping Yan

Journal of Coordination Chemistry, 2014, 67, 3598
DOI: 10.1080/00958972.2014.973867

Dinuclear Gold(I) Pyrrolidinedithiocarbamato Complex: Cytotoxic and Antimigratory Activities on Cancer Cells and the Use of Metal–Organic Framework

Raymond Wai‐Yin Sun, Ming Zhang, Dan Li, Zhi‐Feng Zhang, Hong Cai, Mian Li, Yue‐Jiao Xian, Seik Weng Ng and Alice Sze‐Tsai Wong

Chemistry A European J, 2015, 21, 18534
DOI: 10.1002/chem.201503656

Dinuclear cyclometallated platinum(III) complexes. Relationship between molecular structure and crystal packing

Antonio Rodríguez, Ma José Romero, Alberto Fernández, Margarita López-Torres, Digna Vázquez-García, Leticia Naya, José M. Vila and Jesús J. Fernández

Polyhedron, 2014, 67, 160
DOI: 10.1016/j.poly.2013.08.060

Facile synthesis of morphology- and size-controllable polythiophene/gold composites in aqueous medium

Quanhui Guo, Shuangshuang Zou, Juan Li, Dongfeng Li, Hexian Jiao and Jiahua Shi

J Nanopart Res, 2014, 16
DOI: 10.1007/s11051-014-2702-x

Complexes of platinum(II/IV) with 2-phenylpyridine derivatives as a new class of promising anti-cancer agents

Ming-Xiong Tan, Zhen-Feng Wang, Qi-Pin Qin, Xiao-Ling Huang, Bi-Qun Zou and Hong Liang

Inorganic Chemistry Communications, 2019, 108, 107510
DOI: 10.1016/j.inoche.2019.107510

Investigation on Optical and Biological Properties of 2‐(4‐Dimethylaminophenyl)benzothiazole Based Cycloplatinated Complexes

Rebeca Lara, Gonzalo Millán, M. Teresa Moreno, Elena Lalinde, Elvira Alfaro‐Arnedo, Icíar P. López, Ignacio M. Larráyoz and José G. Pichel

Chemistry A European J, 2021, 27, 15757
DOI: 10.1002/chem.202102737

Exploiting Core–Shell Synergy for Nanosynthesis and Mechanistic Investigation

Hong Wang, Liyong Chen, Yuhua Feng and Hongyu Chen

Acc. Chem. Res., 2013, 46, 1636
DOI: 10.1021/ar400020j

Changing the Emission Properties of Phosphorescent C^C*‐Cyclometalated Thiazol‐2‐ylidene Platinum(II) Complexes by Variation of the β‐Diketonate Ligands

Hendrik Leopold, Ute Heinemeyer, Gerhard Wagenblast, Ingo Münster and Thomas Strassner

Chemistry A European J, 2017, 23, 1118
DOI: 10.1002/chem.201604456

Benzothiazole‐Based Cycloplatinated Chromophores: Synthetic, Optical, and Biological Studies

Elena Lalinde, Rebeca Lara, Icíar P. López, M. Teresa Moreno, Elvira Alfaro‐Arnedo, José G. Pichel and Sergio Piñeiro‐Hermida

Chemistry A European J, 2018, 24, 2440
DOI: 10.1002/chem.201705267

Selective Formation of cis‐N‐Heterocyclic Carbene‐PtII‐Pnictogen Complexes and in vitro Evaluation of Their Cytotoxic Activities toward Cancer Cells

Mathilde Bouché, Georges Dahm, Aline Maisse‐François, Thierry Achard and Stéphane Bellemin‐Laponnaz

Eur J Inorg Chem, 2016, 2016, 2828
DOI: 10.1002/ejic.201600296

Light-emitting anticancer Pt-cyclometalated phenanthroimidazole complexes

Somayee Heydari, Hashem Shahroosvand, Abbas Bahari and Sebastiano Bellani

Journal of Inorganic Biochemistry, 2026, 275, 113121
DOI: 10.1016/j.jinorgbio.2025.113121

Cyclometalated Gold(III) Complexes Containing N‐Heterocyclic Carbene Ligands Engage Multiple Anti‐Cancer Molecular Targets

Sin Ki Fung, Taotao Zou, Bei Cao, Pui‐Yan Lee, Yi Man Eva Fung, Di Hu, Chun‐Nam Lok and Chi‐Ming Che

Angew Chem Int Ed, 2017, 56, 3892
DOI: 10.1002/anie.201612583

PlatinER: A Highly Potent Anticancer Platinum(II) Complex that Induces Endoplasmic Reticulum Stress Driven Immunogenic Cell Death

Max Jing Rui Tham, Maria V. Babak and Wee Han Ang

Angewandte Chemie, 2020, 132, 19232
DOI: 10.1002/ange.202008604

Bio-relevant cobalt(II) complexes with compartmental polyquinoline ligand: Synthesis, crystal structures and biological activities

Jun-Ling Li, Lin Jiang, Bi-Wei Wang, Jin-Lei Tian, Wen Gu, Xin Liu and Shi-Ping Yan

Journal of Inorganic Biochemistry, 2015, 145, 19
DOI: 10.1016/j.jinorgbio.2014.11.003

NATURALLY EFFICIENT EMITTERS: LUMINESCENT ORGANOMETALLIC COMPLEXES DERIVED FROM NATURAL PRODUCTS

WEN-HUA ZHANG and DAVID J. YOUNG

J. Mol. Eng. Mater., 2013, 01, 1330003
DOI: 10.1142/S2251237313300039

Luminescent Palladacycles Containing a Pyrene Chromophor; Synthesis, Biological and Computational Studies of the Interaction with DNA and BSA

Kazem Karami, Azar Ramezanpour, Mostafa Zakariazadeh, Azar Shahpiri, Mahshid Kharaziha and Akram Kazeminasab

ChemistrySelect, 2019, 4, 5126
DOI: 10.1002/slct.201900707

A 19F‐Labeled Probe for the Chiral Discrimination of Thiols and Thioethers

Jiajin Weng, Guangxing Gu, Wei Zhang, Qi Jia, Yining Sun, Jian Wu and Yanchuan Zhao

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202505700

Approaches towards understanding the mechanism-of-action of metallodrugs

Xiaolin Xiong, Liu-Yi Liu, Zong-Wan Mao and Taotao Zou

Coordination Chemistry Reviews, 2022, 453, 214311
DOI: 10.1016/j.ccr.2021.214311

Engineering Supramolecular Assemblies via Metal–Metal Interactions for Biological Applications

Maomao He, Xuequan Zhou, Yuanyuan He, Jiangli Fan, Xiaojun Peng, Jong Seung Kim and Wen Sun

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202516383

Applications of five-membered ring products of cyclometalation reactions as anticancer agents

Iwao Omae

Coordination Chemistry Reviews, 2014, 280, 84
DOI: 10.1016/j.ccr.2014.07.019

Hirshfeld and DFT analysis of the N-heterocyclic carbene proligand methylenebis(N-butylimidazolium) as the acetonitrile-solvated diiodide salt

Andrea Cebollada, Alba Vellé and Pablo J. Sanz Miguel

Acta Crystallogr C Struct Chem, 2016, 72, 456
DOI: 10.1107/S2053229616006781

Synthesis, structure and density functional theory calculations of a novel photoluminescent trisarylborane–bismuth(III) complex

Hazem Amarne, Wissam Helal and Suning Wang

Luminescence, 2019, 34, 731
DOI: 10.1002/bio.3667

N‐Heterocyclic Carbene Platinum Complexes: A Big Step Forward for Effective Antitumor Compounds

Stéphane Bellemin‐Laponnaz

Eur J Inorg Chem, 2020, 2020, 10
DOI: 10.1002/ejic.201900960

Applications of cyclometalation reaction five-membered ring products

Iwao Omae

Journal of Organometallic Chemistry, 2018, 869, 88
DOI: 10.1016/j.jorganchem.2018.05.015

Luminescent Cycloplatinated Complexes with Biologically Relevant Phosphine Ligands: Optical and Cytotoxic Properties

Gonzalo Millán, Nora Giménez, Rebeca Lara, Jesús R. Berenguer, M. Teresa Moreno, Elena Lalinde, Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida and José G. Pichel

Inorg. Chem., 2019, 58, 1657
DOI: 10.1021/acs.inorgchem.8b03211

Exploring Nitrogen Ligand Diversity in trans‐N‐Heterocyclic Carbene–Amine Platinum Complexes : Synthesis, Characterization, and Application to Fluorescence

Edith Chardon, Georges Dahm, Gilles Guichard and Stéphane Bellemin‐Laponnaz

Chemistry An Asian Journal, 2013, 8, 1232
DOI: 10.1002/asia.201201148

Synthesis, structural characterization and in vitro anti-cancer activity of functionalized N-heterocyclic carbene platinum and palladium complexes

Georges Dahm, Corinne Bailly, Lydia Karmazin and Stéphane Bellemin-Laponnaz

Journal of Organometallic Chemistry, 2015, 794, 115
DOI: 10.1016/j.jorganchem.2015.07.003

Luminescent Platinum(II) Complexes with a Tridentate Caffeine‐Based NHC‐Pincer Ligand: Synthesis, Electrochemistry and Photophysics

Oliver Bysewski, Niklas Klosterhalfen, Rose Jordan, Lukas Kletsch, Andreas Winter, Axel Klein, Benjamin Dietzek‐Ivanšić and Ulrich S. Schubert

Eur J Inorg Chem, 2024, 27
DOI: 10.1002/ejic.202300620

Influence of Ligand and Nuclearity on the Cytotoxicity of Cyclometallated C^N^C Platinum(II) Complexes

Angélique Kergreis, Rianne M. Lord and Sarah J. Pike

Chemistry A European J, 2020, 26, 14938
DOI: 10.1002/chem.202002517

Novel 2-(2,5-methoxy-phenyl) imidazo [4,5-f]-[1, 10] phenanthrolin platinum(II) complex display high anticancer activity via dysfunction of mitochondrial signaling pathway

Yi-Dong Bin, Yan Yang, Xu-Jian Luo and Hua-Xin Zhang

Inorganic Chemistry Communications, 2019, 101, 99
DOI: 10.1016/j.inoche.2019.01.017

A novel route to synthesis polythiophene with great yield and high electrical conductivity without post doping process

David Thanasamy, Dominic Jesuraj, Satheesh Kumar Konda kannan and Vanaja Avadhanam

Polymer, 2019, 175, 32
DOI: 10.1016/j.polymer.2019.03.042

A 19F‐Labeled Probe for the Chiral Discrimination of Thiols and Thioethers

Jiajin Weng, Guangxing Gu, Wei Zhang, Qi Jia, Yining Sun, Jian Wu and Yanchuan Zhao

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202505700

Controlled accommodation of metal nanostructures within the matrices of polymer architectures through solution-based synthetic strategies

Haiqing Li, Johnson V. John, Seong Jin Byeon, Min Seon Heo, Jun Hak Sung, Kwang-Ho Kim and Il Kim

Progress in Polymer Science, 2014, 39, 1878
DOI: 10.1016/j.progpolymsci.2014.07.005

Cyclometalated Palladium(II) N‐Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression

Tommy Tsz‐Him Fong, Chun‐Nam Lok, Clive Yik‐Sham Chung, Yi‐Man Eva Fung, Pui‐Keong Chow, Pui‐Ki Wan and Chi‐Ming Che

Angewandte Chemie, 2016, 128, 12114
DOI: 10.1002/ange.201602814

Metallkomplexe mit N‐heterocyclischen Carbenliganden: Entwicklungsmöglichkeiten für metallhaltige Krebsmedikamente

Federico Cisnetti and Arnaud Gautier

Angewandte Chemie, 2013, 125, 12194
DOI: 10.1002/ange.201306682

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N‐Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

Taotao Zou, Ching Tung Lum, Chun‐Nam Lok, Wai‐Pong To, Kam‐Hung Low and Chi‐Ming Che

Angewandte Chemie, 2014, 126, 5920
DOI: 10.1002/ange.201400142

Overoxidation of Intrinsically Conducting Polymers

Rudolf Holze

Polymers, 2022, 14, 1584
DOI: 10.3390/polym14081584

Catalytic Dehydration of Fructose into 5‐Hydroxymethylfurfural by a DMSO‐like Polymeric Solid Organocatalyst

Xiawei Guo, Jinqiang Tang, Bo Xiang, Liangfang Zhu, Huaqing Yang and Changwei Hu

ChemCatChem, 2017, 9, 3218
DOI: 10.1002/cctc.201700136

Preparation of polymeric vesicles through ultrasonic treatment of poly(styrene‐block‐2‐vinylpyridine) micelles under alkaline conditions

Jinhao Liu, Lianlian Song, Xiaokai Zhang and Xue Li

J Polym Sci B Polym Phys, 2014, 52, 953
DOI: 10.1002/polb.23514

Measuring the Unusually Slow Ionic Diffusion in Polyaniline via Study of Yolk-Shell Nanostructures

Hang Sun, Xiaoshuang Shen, Lin Yao, Shuangxi Xing, Hong Wang, Yuhua Feng and Hongyu Chen

J. Am. Chem. Soc., 2012, 134, 11243
DOI: 10.1021/ja3036674

Bioactive Luminescent Transition‐Metal Complexes for Biomedical Applications

Dik‐Lung Ma, Hong‐Zhang He, Ka‐Ho Leung, Daniel Shiu‐Hin Chan and Chung‐Hang Leung

Angew Chem Int Ed, 2013, 52, 7666
DOI: 10.1002/anie.201208414

Platinum(II) and Gold(III) Allenylidene Complexes: Phosphorescence, Self‐Assembled Nanostructures and Cytotoxicity

Xin‐Shan Xiao, Wai‐Lun Kwong, Xiangguo Guan, Chen Yang, Wei Lu and Chi‐Ming Che

Chemistry A European J, 2013, 19, 9457
DOI: 10.1002/chem.201301481

Photofunctional Platinum Complexes Featuring N‐heterocyclic Carbene‐Based Pincer Ligands

Wan‐Jung Lin, Abbas Raja Naziruddin, Yu‐Hsuan Chen, Bian‐Jian Sun, A. Hsiu Hwa Chang, Wen‐Jwu Wang and Wen‐Shu Hwang

Chemistry An Asian Journal, 2015, 10, 728
DOI: 10.1002/asia.201403306

Rational design of platinum(II) complexes with orthogonally oriented triazolyl ligand with emission enhancement characteristics for cancer chemotherapy in vivo

Yeye Ai, Zherui Zhang, Yuexuan Fei, Ruirong Ye, Angela Sin-Yee Law, Zong-Wan Mao, Junqiu Liu, Yongguang Li and Vivian Wing-Wah Yam

Sci. China Chem., 2023, 66, 2878
DOI: 10.1007/s11426-023-1702-x

Cyclometalated Palladium(II) N‐Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression

Tommy Tsz‐Him Fong, Chun‐Nam Lok, Clive Yik‐Sham Chung, Yi‐Man Eva Fung, Pui‐Keong Chow, Pui‐Ki Wan and Chi‐Ming Che

Angew Chem Int Ed, 2016, 55, 11935
DOI: 10.1002/anie.201602814