Intramolecular nitrone dipolar cycloadditions: control of regioselectivity and synthesis of naturally-occurring spirocyclic alkaloids

Alastair J. Hodges, Joseph P. Adams, Andrew D. Bond, Andrew B. Holmes, Neil J. Press, Stephen D. Roughley, John H. Ryan, Simon Saubern, Catherine J. Smith, Michael D. Turnbull and Annabella F. Newton

Org. Biomol. Chem., 2012, 10, 8963
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Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines: dual stereocontrol with nearly perfect diastereoselectivity

Yi-Shuang Zhao, Qiang Liu, Ping Tian, Jing-Chao Tao and Guo-Qiang Lin

Org. Biomol. Chem., 2015, 13, 4174
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Thirty-five years of synthetic studies directed towards the histrionicotoxin family of alkaloids

Alex Sinclair and Robert A. Stockman

Nat. Prod. Rep., 2007, 24, 298
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On the use of anomeric hydroxylamines in the reverse-Cope cyclisation

Nigel P. Bainbridge, Angela C. Currie, Nicholas J. Cooper, James C. Muir, David W. Knight and Jonathan M. Walton

Tetrahedron Letters, 2007, 48, 7782
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The enantioselective synthesis of poison-frog alkaloids (−)-203A, (−)-209B, (−)-231C, (−)-233D, and (−)-235B″

Naoki Toyooka, Zhou Dejun, Hideo Nemoto, H. Martin Garraffo, Thomas F. Spande and John W. Daly

Tetrahedron Letters, 2006, 47, 577
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A Gram‐Scale Batch and Flow Total Synthesis of Perhydrohistrionicotoxin

Malte Brasholz, James M. Macdonald, Simon Saubern, John H. Ryan and Andrew B. Holmes

Chemistry A European J, 2010, 16, 11471
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Tuning the Regioselectivity of Gold-Catalyzed Internal Nitroalkyne Redox: A Cycloisomerization and [3 + 2]-Cycloaddition Cascade for the Construction of spiro-Pseudoindoxyl Skeleton

Chepuri V. Suneel Kumar and Chepuri V. Ramana

Org. Lett., 2014, 16, 4766
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Total Synthesis of (−)-Histrionicotoxin 285A and (−)-Perhydrohistrionicotoxin

James M. Macdonald, Helen T. Horsley, John H. Ryan, Simon Saubern and Andrew B. Holmes

Org. Lett., 2008, 10, 4227
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A Concise Total Synthesis of dl-Histrionicotoxin

Maheswaran S. Karatholuvhu, Alex Sinclair, Annabella F. Newton, Marie-Lyne Alcaraz, Robert A. Stockman and Philip L. Fuchs

J. Am. Chem. Soc., 2006, 128, 12656
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Electrophilic [N—F]+ catalysed asymmetric allylation of (E)‐N,1‐diphenylmethanimine

Poonam Sharma and Rakesh K. Sharma

Chirality, 2019, 31, 91
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2‐Iodoxybenzoic Acid—A Simple Oxidant with a Dazzling Array of Potential Applications

Alexander Duschek and Stefan F. Kirsch

Angew Chem Int Ed, 2011, 50, 1524
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First enantioselective synthesis of (+)-quinolizidine : determination of the absolute stereochemistry

Naoki Toyooka and Hideo Nemoto

Tetrahedron Letters, 2003, 44, 569
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Flow synthesis of tricyclic spiropiperidines as building blocks for the histrionicotoxin family of alkaloids

Malte Brasholz, Brian A. Johnson, James M. Macdonald, Anastasios Polyzos, John Tsanaktsidis, Simon Saubern, Andrew B. Holmes and John H. Ryan

Tetrahedron, 2010, 66, 6445
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Total Synthesis of the Antipode of Alkaloid 205 B

Naoki Toyooka, Ayako Fukutome, Hiroyuki Shinoda and Hideo Nemoto

Angewandte Chemie, 2003, 115, 3938
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Recent approaches to the construction of 1-azaspiro[4.5]decanes and related 1-azaspirocycles

Gregory Dake

Tetrahedron, 2006, 62, 3467
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Synthesis of Alkaloid Analogues from α‐Amino Acids by One‐Pot Radical Decarboxylation/Alkylation

Alicia Boto, Yolanda De León, Juan Antonio Gallardo and Rosendo Hernández

Eur J Org Chem, 2005, 2005, 3461
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Domino Grignard Addition/Cope–House Reaction for the Synthesis of Polyhydroxylated 3-Methylindolizidines Analogous to Castanospermine

Thomas Lulli, Filippo Dei, Macarena Martínez-Bailén, Camilla Matassini, Cristina Faggi, Francesca Cardona and Andrea Goti

Org. Lett., 2025, 27, 10098
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Intermolecular Cope-Type Hydroamination of Alkenes and Alkynes using Hydroxylamines

Joseph Moran, Serge I. Gorelsky, Elena Dimitrijevic, Marie-Eve Lebrun, Anne-Catherine Bédard, Catherine Séguin and André M. Beauchemin

J. Am. Chem. Soc., 2008, 130, 17893
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Total Synthesis of the Antipode of Alkaloid 205 B

Naoki Toyooka, Ayako Fukutome, Hiroyuki Shinoda and Hideo Nemoto

Angew Chem Int Ed, 2003, 42, 3808
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Total Synthesis of Paxdaphnine A and Daphlongamine B via an Aza-Prins Cyclization Strategy

Lu Ren, Zhaohong Lu, Dimin Wu, Mingchen Ma and Ang Li

J. Am. Chem. Soc., 2025, 147, 27137
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The Total Synthesis of Alkaloids (‐)‐Histrionicotoxin 259A (IIIc), 285C (IIIb) and 285E (IIIa).

Catherine J. Smith, Andrew B. Holmes and Neil J. Press

ChemInform, 2002, 33, 210
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Transition metals in organic synthesis: highlights for the year 2002

Björn C.G. Söderberg

Coordination Chemistry Reviews, 2004, 248, 1085
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2‐Iodoxybenzoesäure – ein einfaches Oxidationsmittel mit einer Vielfalt an Anwendungsmöglichkeiten

Alexander Duschek and Stefan F. Kirsch

Angewandte Chemie, 2011, 123, 1562
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The reverse Cope cyclisation: a classical reaction goes backwards

Nicholas J. Cooper and David W. Knight

Tetrahedron, 2004, 60, 243
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Entropy versus tether strain effects on rates of intramolecular 1,3-dipolar cycloadditions of N-alkenylnitrones

Elizabeth H. Krenske, K.N. Houk, Andrew B. Holmes and John Thompson

Tetrahedron Letters, 2011, 52, 2181
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Causation in a Cascade: The Origins of Selectivities in Intramolecular Nitrone Cycloadditions

Elizabeth H. Krenske, Sesil Agopcan, Viktorya Aviyente, K. N. Houk, Brian A. Johnson and Andrew B. Holmes

J. Am. Chem. Soc., 2012, 134, 12010
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Titanium carbenoid reagents for converting carbonyl groups into alkenes

Richard C. Hartley, Jianfeng Li, Calver A. Main and Gordon J. McKiernan

Tetrahedron, 2007, 63, 4825
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Advances in the Total Synthesis of Pharmacologically Important Fused Indolizidine Alkaloids: Securinine, Gephyrotoxin and Lepadiformine

Afiqah A.A. Ali, Agustono Wibowo, Nor H.M. Rosli, Jhi B. Foo, Mohd F. Mohammat and Jason S.E. Loo

COS, 2025, 22, 288
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