Issue 41, 2019

Advances in portable electrospinning devices for in situ delivery of personalized wound care

Abstract

Electrospinning and electrospun fibrous assemblies have attracted interest in a variety of biomedical fields including woundcare, tissue engineering and drug delivery, due to the large surface-area-to-volume ratio and high porosity of nanofibrous webs. Normally, wound dressings are manufactured well before the point of care, and then packaged and distributed for use at a later stage. More recently, in situ electrospinning of fibers directly onto wound sites has been proposed as a route to personalized wound dressing manufacture, tailored to the needs of individual patients. Practically, in situ deposition of nanofibers on to a wound could be envisaged using a portable or hand-held electrospinning device that is safe and easy to operate. This review focuses on recent advances in portable electrospinning technology and potential applications in woundcare and regenerative medicine. The main research challenges and future trends are also considered.

Graphical abstract: Advances in portable electrospinning devices for in situ delivery of personalized wound care

Article information

Article type
Minireview
Submitted
02 4 2019
Accepted
09 5 2019
First published
09 5 2019

Nanoscale, 2019,11, 19166-19178

Advances in portable electrospinning devices for in situ delivery of personalized wound care

X. Yan, M. Yu, S. Ramakrishna, S. J. Russell and Y. Long, Nanoscale, 2019, 11, 19166 DOI: 10.1039/C9NR02802A

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