Issue 14, 2016

An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

Abstract

A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells.

Graphical abstract: An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

Supplementary files

Article information

Article type
Paper
Submitted
11 10 2015
Accepted
19 11 2015
First published
19 11 2015

J. Mater. Chem. C, 2016,4, 2909-2914

Author version available

An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols

L. Cui, Y. Baek, S. Lee, N. Kwon and J. Yoon, J. Mater. Chem. C, 2016, 4, 2909 DOI: 10.1039/C5TC03272E

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