The cholesterol-lowering agent mevinolin 1 has been degraded to the enone 4 which had previously been synthesized and converted into mevinolin1, compactin 2 and 3-ethylconipactin3.
D. L. J. Clive and C. Zhang, J. Chem. Soc., Chem. Commun., 1993, 647 DOI: 10.1039/C39930000647
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