Issue 11, 2024

Non-destructive real-time monitoring and investigation of the self-assembly process using fluorescent probes

Abstract

Self-assembly has been considered as a strategy to construct superstructures with specific functions, which has been widely used in many different fields, such as bionics, catalysis, and pharmacology. A detailed and in-depth analysis of the self-assembly mechanism is beneficial for directionally and accurately regulating the self-assembly process of substances. Fluorescent probes exhibit unique advantages of sensitivity, non-destructiveness, and real-time self-assembly tracking, compared with traditional methods. In this work, the design principle of fluorescent probes with different functions and their applications for the detection of thermodynamic and kinetic parameters during the self-assembly process were systematically reviewed. Their efficiency, limitations and advantages are also discussed. Furthermore, the promising perspectives of fluorescent probes for investigating the self-assembly process are also discussed and suggested.

Graphical abstract: Non-destructive real-time monitoring and investigation of the self-assembly process using fluorescent probes

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Article information

Article type
Review Article
Submitted
05 12 2023
Accepted
22 1 2024
First published
17 2 2024
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY-NC license

Chem. Sci., 2024,15, 3800-3830

Non-destructive real-time monitoring and investigation of the self-assembly process using fluorescent probes

X. Ji, N. Wang, J. Wang, T. Wang, X. Huang and H. Hao, Chem. Sci., 2024, 15, 3800 DOI: 10.1039/D3SC06527H

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