Issue 23, 2024

Lanthanide-based nanomaterials for temperature sensing in the near-infrared spectral region: illuminating progress and challenges

Abstract

Being first proposed as a method to overcome limitations associated with conventional contact thermometers, luminescence thermometry has been extensively studied over the past two decades as a sensitive and fast approach to remote and minimally invasive thermal sensing. Herein, lanthanide (Ln)-doped nanoparticles (Ln-NPs) have been identified as particularly promising candidates, given their outstanding optical properties. Known primarily for their upconversion emission, Ln-NPs have also been recognized for their ability to be excited with and emit in the near-infrared (NIR) regions matching the NIR transparency windows. This sparked the emergence of the development of NIR-NIR Ln-NPs for a wide range of temperature-sensing applications. The shift to longer excitation and emission wavelengths resulted in increased efforts being put into developing nanothermometers for biomedical applications, however most research is still preclinical. This mini-review outlines and addresses the challenges that limit the reliability and implementation of luminescent nanothermometers to real-life applications. Through a critical look into the recent developments from the past 4 years, we highlight attempts to overcome some of the limitations associated with excitation wavelength, thermal sensitivity, calibration, as well as light-matter interactions. Strategies range from use of longer excitation wavelengths, brighter emitters through strategic core/multi-shell architectures, exploitation of host phonons, and a shift from double- to single-band ratiometric as well as lifetime-based approaches to innovative methods based on computation and machine learning. To conclude, we offer a perspective on remaining gaps and where efforts should be focused towards more robust nanothermometers allowing a shift to real-life, e.g., in vivo, applications.

Graphical abstract: Lanthanide-based nanomaterials for temperature sensing in the near-infrared spectral region: illuminating progress and challenges

Article information

Article type
Minireview
Submitted
20 1 2024
Accepted
04 4 2024
First published
05 4 2024

Nanoscale, 2024,16, 10975-10993

Lanthanide-based nanomaterials for temperature sensing in the near-infrared spectral region: illuminating progress and challenges

A. Puccini, N. Liu and E. Hemmer, Nanoscale, 2024, 16, 10975 DOI: 10.1039/D4NR00307A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements