Issue 11, 2024

Recent advances in methods for live-cell RNA imaging

Abstract

As one of the most fundamental building blocks of life, RNA plays critical roles in diverse biological processes, from X chromosome inactivation, genome stability maintenance, to embryo development. Being able to visualize the localization and dynamics of RNA can provide critical insights into these fundamental processes. In this review, we provide an overview of current methods for live-cell RNA imaging with a focus on methods for visualizing RNA in living mammalian cells with single-molecule resolution.

Graphical abstract: Recent advances in methods for live-cell RNA imaging

Article information

Article type
Minireview
Submitted
10 1 2024
Accepted
21 2 2024
First published
21 2 2024

Nanoscale, 2024,16, 5537-5545

Recent advances in methods for live-cell RNA imaging

T. G. Pham and J. Wu, Nanoscale, 2024, 16, 5537 DOI: 10.1039/D4NR00129J

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