Issue 12, 2024

Applications of self-assembled peptide hydrogels in anti-tumor therapy

Abstract

Peptides are a class of active substances composed of a variety of amino acids with special physiological functions. The rational design of peptide sequences at the molecular level enables their folding into diverse secondary structures. This property has garnered significant attention in the biomedical sphere owing to their favorable biocompatibility, adaptable mechanical traits, and exceptional loading capabilities. Concurrently with advancements in modern medicine, the diagnosis and treatment of tumors have increasingly embraced targeted and personalized approaches. This review explores recent applications of self-assembled peptides derived from natural amino acids in chemical therapy, immunotherapy, and other adjunctive treatments. We highlighted the utilization of peptide hydrogels as delivery systems for chemotherapeutic drugs and other bioactive molecules and then discussed the challenges and prospects for their future application.

Graphical abstract: Applications of self-assembled peptide hydrogels in anti-tumor therapy

Article information

Article type
Review Article
Submitted
29 2 2024
Accepted
29 4 2024
First published
30 4 2024
This article is Open Access
Creative Commons BY-NC license

Nanoscale Adv., 2024,6, 2993-3008

Applications of self-assembled peptide hydrogels in anti-tumor therapy

Y. Hua and Y. Shen, Nanoscale Adv., 2024, 6, 2993 DOI: 10.1039/D4NA00172A

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