Issue 49, 2024

Aminoarylation of alkynes using diarylanilines

Abstract

Intermolecular aminoarylation of alkynes is described, via addition of diarylanilines to alkynes and Smiles–Truce rearrangement. The transformation manipulates the C–N bond of anilines directly, with no requirement for organometallic reagents or transition metal catalysis. The enaminoate products are versatile building blocks for different classes of heterocycles.

Graphical abstract: Aminoarylation of alkynes using diarylanilines

Supplementary files

Article information

Article type
Communication
Submitted
24 4 2024
Accepted
21 5 2024
First published
22 5 2024
This article is Open Access
Creative Commons BY license

Chem. Commun., 2024,60, 6296-6299

Aminoarylation of alkynes using diarylanilines

Z. Liu and M. F. Greaney, Chem. Commun., 2024, 60, 6296 DOI: 10.1039/D4CC01935K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements