Issue 27, 2024

Light-activated g-C3N4 photoelectrodes with a selective molecular sieve for in vivo quantification of oxygen levels in the living mouse brain

Abstract

A novel micro-photoelectrode with a selective molecular sieve was created for in vivo monitoring of O2 levels in the mouse brain. An ITO optical fiber modified by graphitized carbon nitride (g-C3N4) in situ was employed as the light activated substrate to provide rich photo-induced electrons for the catalytic reduction of O2. Meanwhile, the porous hybrid layer composed of zeolitic imidazolate framework-8 and polysulfone was constructed over the g-C3N4 surface as the molecular sieve to synergically enhance the selectivity of O2 detections. By advantage of this useful tool, the real time variation of the O2 level was successfully determined in the mouse brain upon ischemia.

Graphical abstract: Light-activated g-C3N4 photoelectrodes with a selective molecular sieve for in vivo quantification of oxygen levels in the living mouse brain

Supplementary files

Article information

Article type
Communication
Submitted
17 1 2024
Accepted
26 2 2024
First published
02 3 2024

Chem. Commun., 2024,60, 3685-3688

Light-activated g-C3N4 photoelectrodes with a selective molecular sieve for in vivo quantification of oxygen levels in the living mouse brain

Y. Da, Q. Sun, L. Zhang and Y. Tian, Chem. Commun., 2024, 60, 3685 DOI: 10.1039/D4CC00246F

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