Issue 41, 2023

Single-atom nanozymes: classification, regulation strategy, and safety concerns

Abstract

Nanozymes, nanomaterials possessing enzymatic activity, have been studied extensively by researchers. However, their complex composition, low density of active sites, and inadequate substrate selectivity have hindered the maturation and widespread acceptance of nanozymes. Single-atom nanozymes (SAzymes) with atomically dispersed active sites are leading the field of catalysis due to their exceptional performance. The maximum utilization rate of atoms, low cost, well-defined coordination structure, and active sites are the most prominent advantages of SAzymes that researchers favor. This review systematically categorizes SAzymes based on their support type and describes their specific applications. Additionally, we discuss regulation strategies for SAzyme activity and provide a comprehensive summary of biosafety challenges associated with these enzymes.

Graphical abstract: Single-atom nanozymes: classification, regulation strategy, and safety concerns

Article information

Article type
Review Article
Submitted
21 7 2023
Accepted
08 9 2023
First published
11 9 2023

J. Mater. Chem. B, 2023,11, 9840-9866

Single-atom nanozymes: classification, regulation strategy, and safety concerns

J. Han, Y. Gu, C. Yang, L. Meng, R. Ding, Y. Wang, K. Shi and H. Yao, J. Mater. Chem. B, 2023, 11, 9840 DOI: 10.1039/D3TB01644G

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