Issue 16, 2023

A field guide to flow chemistry for synthetic organic chemists

Abstract

Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By “lifting the veil” on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.

Graphical abstract: A field guide to flow chemistry for synthetic organic chemists

Supplementary files

Article information

Article type
Review Article
Submitted
22 2 2023
Accepted
15 3 2023
First published
15 3 2023
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2023,14, 4230-4247

A field guide to flow chemistry for synthetic organic chemists

L. Capaldo, Z. Wen and T. Noël, Chem. Sci., 2023, 14, 4230 DOI: 10.1039/D3SC00992K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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